CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through bim-mediated intrinsic apoptosis

PLoS ONE

Volumn 5, Issue 9, 2010, Pages 1-12

  Drury, Luke J ^a   Wendt, Michael K ^a,b   Dwinell, Michael B ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; CASPASE; CASPASE 9; CRYSTAL VIOLET; CYTOCHROME C; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; PERTUSSIS TOXIN; POLYMACON; PROPIDIUM IODIDE; PROTEIN BCL 2; PROTEIN MCL 1; STROMAL CELL DERIVED FACTOR 1; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; MEMBRANE PROTEIN; ONCOPROTEIN;

ANOIKIS; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL ADHESION; CELL STRAIN HCT116; CELL STRAIN HT29; COLORECTAL CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; FOCAL ADHESION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; LIVER TUMOR; METASTASIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STAINING; TUMOR GROWTH; ANIMAL; COLORECTAL TUMOR; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MOUSE; MOUSE MUTANT; PATHOPHYSIOLOGY; PROTEIN TRANSPORT; TUMOR CELL LINE;

ANIMALS; ANOIKIS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL ADHESION; CELL LINE, TUMOR; CHEMOKINE CXCL12; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, SCID; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION;

EID: 77958506768     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012895     Document Type: Article

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