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Volumn 713, Issue , 2011, Pages 89-103

Genome-Wide Association Studies

Author keywords

Association; Epidemiology; Genetics; Genome wide; Statistics

Indexed keywords

CONTROLLED STUDY; EFFECT SIZE; GENETIC MARKER; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING; QUALITY CONTROL; ALGORITHM; ARTICLE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; METHODOLOGY; POPULATION GENETICS; REPRODUCIBILITY; SAMPLE SIZE;

EID: 79952600660     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60327-416-6_7     Document Type: Chapter
Times cited : (4)

References (41)
  • 1
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273(5281): 1516–1517.
    • (1996) Science , vol.273 , Issue.5281 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 2
    • 0029805706 scopus 로고    scopus 로고
    • The new genomics: Global views of biology
    • Lander ES (1996) The new genomics: global views of biology. Science 274(5287): 536–539.
    • (1996) Science , vol.274 , Issue.5287 , pp. 536-539
    • Lander, E.S.1
  • 3
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • International HapMap Consortium (2003) The International HapMap Project. Nature 426: 789–796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 4
    • 34249996115 scopus 로고    scopus 로고
    • A common allele on chromosome 9 associated with coronary heart disease
    • McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R et al (2007) A common allele on chromosome 9 associated with coronary heart disease. Science 316(5830): 1488–1491.
    • (2007) Science , vol.316 , Issue.5830 , pp. 1488-1491
    • McPherson, R.1    Pertsemlidis, A.2    Kavaslar, N.3    Stewart, A.4    Roberts, R.5
  • 5
    • 34250010480 scopus 로고    scopus 로고
    • A common variant on chromosome 9p21 affects the risk of myocardial infarction
    • Helgadottir A, Thorleifsson G, Manolescu A, Gretarsdottir S, Blondal T et al (2007) A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 316(5830): 1491–1493.
    • (2007) Science , vol.316 , Issue.5830 , pp. 1491-1493
    • Helgadottir, A.1    Thorleifsson, G.2    Manolescu, A.3    Gretarsdottir, S.4    Blondal, T.5
  • 6
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661–678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 8
    • 34047274599 scopus 로고    scopus 로고
    • A genome-wide genotyping study in patients with ischaemic stroke: Initial analysis and data release
    • Matarin M, Brown WM, Scholz S, Simon-Sanchez J, Fung HC et al (2007) A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release. Lancet Neurol 6(5): 414–420.
    • (2007) Lancet Neurol , vol.6 , Issue.5 , pp. 414-420
    • Matarin, M.1    Brown, W.M.2    Scholz, S.3    Simon-Sanchez, J.4    Fung, H.C.5
  • 9
    • 34250001297 scopus 로고    scopus 로고
    • A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
    • Hunter DJ, Kraft P, Jacobs KB, Cox DG, Yeager M et al (2007) A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet 39(7): 870–874.
    • (2007) Nat Genet , vol.39 , Issue.7 , pp. 870-874
    • Hunter, D.J.1    Kraft, P.2    Jacobs, K.B.3    Cox, D.G.4    Yeager, M.5
  • 10
    • 34250002140 scopus 로고    scopus 로고
    • Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer
    • Stacey SN, Manolescu A, Sulem P, Rafnar T, Gudmundsson J et al (2007) Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 39(7): 865–869.
    • (2007) Nat Genet , vol.39 , Issue.7 , pp. 865-869
    • Stacey, S.N.1    Manolescu, A.2    Sulem, P.3    Rafnar, T.4    Gudmundsson, J.5
  • 11
    • 34250006413 scopus 로고    scopus 로고
    • Genome-wide association study identifies novel breast cancer susceptibility loci
    • Easton DF, Pooley KA, Dunning AM, Pharoah PDP, Thompson D et al (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447: 1087–1093.
    • (2007) Nature , vol.447 , pp. 1087-1093
    • Easton, D.F.1    Pooley, K.A.2    Dunning, A.M.3    Pharoah, P.D.P.4    Thompson, D.5
  • 12
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel risk loci for type 2 diabetes
    • Sladek R, Rocheleau G, Rung J, Dina C, Shen L et al (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 445(7130): 881–885.
    • (2007) Nature , vol.445 , Issue.7130 , pp. 881-885
    • Sladek, R.1    Rocheleau, G.2    Rung, J.3    Dina, C.4    Shen, L.5
  • 13
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI et al (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316(5829): 1331–1336.
    • (2007) Science , vol.316 , Issue.5829 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3    Burtt, N.P.4    de Bakker, P.I.5
  • 14
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316(5829): 1336–1341.
    • (2007) Science , vol.316 , Issue.5829 , pp. 1336-1341
    • Zeggini, E.1    Weedon, M.N.2    Lindgren, C.M.3    Frayling, T.M.4    Elliott, K.S.5
  • 15
    • 34249885875 scopus 로고    scopus 로고
    • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
    • Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y et al (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316(5829): 1341–1345.
    • (2007) Science , vol.316 , Issue.5829 , pp. 1341-1345
    • Scott, L.J.1    Mohlke, K.L.2    Bonnycastle, L.L.3    Willer, C.J.4    Li, Y.5
  • 16
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316(5826): 889–894.
    • (2007) Science , vol.316 , Issue.5826 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3    Zeggini, E.4    Freathy, R.M.5
  • 18
    • 34547755055 scopus 로고    scopus 로고
    • Type 2 diabetes whole-genome association study in four populations: The DiaGen consortium
    • Salonen JT, Uimari P, Aalto JM, Pirskanen M, Kaikkonen J et al (2007) Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Am J Hum Genet 81(2): 338–345.
    • (2007) Am J Hum Genet , vol.81 , Issue.2 , pp. 338-345
    • Salonen, J.T.1    Uimari, P.2    Aalto, J.M.3    Pirskanen, M.4    Kaikkonen, J.5
  • 19
    • 0344033602 scopus 로고    scopus 로고
    • Detecting disease associations due to linkage disequilibrium using haplotype tags: A class of tests and the determinants of statistical power
    • Chapman JM, Cooper JD, Todd JA, Clayton DG (2003) Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power. Hum Hered 56: 18–31.
    • (2003) Hum Hered , vol.56 , pp. 18-31
    • Chapman, J.M.1    Cooper, J.D.2    Todd, J.A.3    Clayton, D.G.4
  • 20
    • 40149111451 scopus 로고    scopus 로고
    • What can genome-wide association studies tell us about the genetics of common disease?
    • Iles MM (2008) What can genome-wide association studies tell us about the genetics of common disease? PLoS Genet 4(2): e33.
    • (2008) Plos Genet , vol.4 , Issue.2 , pp. e33
    • Iles, M.M.1
  • 24
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin B, Roeder K (1999) Genomic control for association studies. Biometrics 55: 997–1004.
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 25
    • 0035528921 scopus 로고    scopus 로고
    • Genomic control: A new approach to genetic-based association studies
    • Devlin B, Roeder K (2001) Genomic control: a new approach to genetic-based association studies. Theor Pop Biol 60: 155–166.
    • (2001) Theor Pop Biol , vol.60 , pp. 155-166
    • Devlin, B.1    Roeder, K.2
  • 26
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38(8): 904–909.
    • (2006) Nat Genet , vol.38 , Issue.8 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 28
    • 0035121797 scopus 로고    scopus 로고
    • Accounting for unmeasured population structure in case-control studies of genetic association using a novel latent-class model
    • Satten G, Flanders WD, Yang O (2001) Accounting for unmeasured population structure in case-control studies of genetic association using a novel latent-class model. Am J Hum Genet 68: 466–477.
    • (2001) Am J Hum Genet , vol.68 , pp. 466-477
    • Satten, G.1    Flanders, W.D.2    Yang, O.3
  • 29
    • 42649093791 scopus 로고    scopus 로고
    • Interpreting principal component analyses of spatial population genetic variation
    • Novembre J, Stephens M (2008) Interpreting principal component analyses of spatial population genetic variation. Nat Genet 40(5): 646–649.
    • (2008) Nat Genet , vol.40 , Issue.5 , pp. 646-649
    • Novembre, J.1    Stephens, M.2
  • 32
    • 58949086544 scopus 로고    scopus 로고
    • Comparison of association methods for dense marker data
    • Bacanu S-A, Nelson MR, Ehm MG (2008) Comparison of association methods for dense marker data. Genet Epidem 32: 791–799.
    • (2008) Genet Epidem , vol.32 , pp. 791-799
    • Bacanu, S.-A.1    Nelson, M.R.2    Ehm, M.G.3
  • 33
    • 25444453244 scopus 로고    scopus 로고
    • Screening large-scale association study data: Exploiting interactions using random forests
    • Lunetta KL, Hayward BL, Segal J, Van Eerdewegh P (2004) Screening large-scale association study data: exploiting interactions using random forests. BMC Genet 5: 32.
    • (2004) BMC Genet , vol.5 , pp. 32
    • Lunetta, K.L.1    Hayward, B.L.2    Segal, J.3    van Eerdewegh, P.4
  • 35
    • 34247563453 scopus 로고    scopus 로고
    • Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24
    • Gudmundsson J, Sulem P, Manolescu A, Amundadottir LT, Gudbjartsson D et al (2007) Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet 39: 631–637.
    • (2007) Nat Genet , vol.39 , pp. 631-637
    • Gudmundsson, J.1    Sulem, P.2    Manolescu, A.3    Amundadottir, L.T.4    Gudbjartsson, D.5
  • 36
    • 34548299105 scopus 로고    scopus 로고
    • Risk alleles for multiple sclerosis identified by a genomewide study
    • International Multiple Sclerosis Genetics Consortium (2007) Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 357(9): 851–862.
    • (2007) N Engl J Med , vol.357 , Issue.9 , pp. 851-862
  • 38
    • 34147119077 scopus 로고    scopus 로고
    • Overcoming the winner’s curse: Estimating penetrance parameters from case-control data
    • Zöllner S, Pritchard JK (2007) Overcoming the winner’s curse: estimating penetrance parameters from case-control data. Am J Hum Genet 80(4): 605–615.
    • (2007) Am J Hum Genet , vol.80 , Issue.4 , pp. 605-615
    • Zöllner, S.1    Pritchard, J.K.2
  • 39
    • 34247386214 scopus 로고    scopus 로고
    • Upward bias in odds ratio estimates from genome-wide association studies
    • Garner C (2007) Upward bias in odds ratio estimates from genome-wide association studies. Genet Epidemiol 31: 288–295.
    • (2007) Genet Epidemiol , vol.31 , pp. 288-295
    • Garner, C.1
  • 40
    • 34249997024 scopus 로고    scopus 로고
    • Replicating genotype-phenotype associations
    • NCI-NHGRI Working Group on Replication in Association Studies (2007) Replicating genotype-phenotype associations. Nature 447: 655–660.
    • (2007) Nature , vol.447 , pp. 655-660
  • 41
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies via imputation of genotypes
    • Marchini J, Howie B, Myers S, McVean G, Donnelly P (2007) A new multipoint method for genome-wide association studies via imputation of genotypes. Nat Genet 39: 906–913.
    • (2007) Nat Genet , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.