Binding Site Identification and Structure Determination of ProteinLigand Complexes by NMR: A Semiautomated Approach

Methods in Enzymology

Volumn 493, Issue , 2011, Pages 241-275

  Ziarek, Joshua J ^a   Peterson, Francis C ^a   Lytle, Betsy L ^a   Volkman, Brian F ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; LIGAND; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; AUTOMATION; BINDING AFFINITY; BINDING SITE; COVALENT BOND; CRYSTALLIZATION; DISSOCIATION CONSTANT; DRUG RESEARCH; EPITOPE MAPPING; HETERONUCLEAR NUCLEAR MAGNETIC RESONANCE; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR LIBRARY; MOLECULAR MODEL; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY; STRUCTURE ANALYSIS; TRANSVERSE RELAXATION OPTIMIZED SPECTROSCOPY;

EID: 79952366609     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-381274-2.00010-8     Document Type: Chapter

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