-
1
-
-
39049104489
-
Cannabinoids for cancer treatment: Progress and promise
-
Sarfaraz, S.; Adhami, V.M.; Syed, D.N.; Afaq F.; Mukhtar, H. Cannabinoids for cancer treatment: progress and promise. Cancer Res. 2008, 68, 339-342.
-
(2008)
Cancer Res
, vol.68
, pp. 339-342
-
-
Sarfaraz, S.1
Adhami, V.M.2
Syed, D.N.3
Afaq, F.4
Mukhtar, H.5
-
2
-
-
33745013193
-
Cannabinoids and cancer: Pros and cons of an antitumour strategy
-
Bifulco, M.; Laezza, C.; Pisanti, S.; Gazzerro, P. Cannabinoids and cancer: pros and cons of an antitumour strategy. Br. J. Pharmacol. 2006, 148, 123-135.
-
(2006)
Br. J. Pharmacol.
, vol.148
, pp. 123-135
-
-
Bifulco, M.1
Laezza, C.2
Pisanti, S.3
Gazzerro, P.4
-
3
-
-
0025954862
-
Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study
-
Herkenham, M.; Lynn, A.B.; Johnson, M.R.; Melvin, L.S.; de Costa, B.R.; Rice, K.C. Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J. Neurosci. 1991, 11, 563-583.
-
(1991)
J. Neurosci.
, vol.11
, pp. 563-583
-
-
Herkenham, M.1
Lynn, A.B.2
Johnson, M.R.3
Melvin, L.S.4
de Costa, B.R.5
Rice, K.C.6
-
4
-
-
33645517680
-
Endogenous cannabinoids in the brain and peripheral tissues: Regulation of their levels and control of food intake
-
Matias, I.; Bisogno, T.; Di Marzo, V. Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. Int. J. Obes. 2006, 30 (Suppl. 1), S7-S12.
-
(2006)
Int. J. Obes.
, vol.30
, Issue.SUPPL. 1
-
-
Matias, I.1
Bisogno, T.2
di Marzo, V.3
-
5
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro, S.; Thomas K.L.; Abu-Shaar, M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993, 365, 61-65.
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
6
-
-
33645106816
-
CB2 receptor-mediated antihyperalgesia: Possible direct involvement of neural mechanisms
-
Beltramo, M.; Bernardini, N.; Bertorelli, R.; Campanella, M.; Nicolussi, E.; Fredduzzi, S.; Reggiani, A. CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms. Eur. J. Neurosci. 2006, 23, 1530-1538.
-
(2006)
Eur. J. Neurosci.
, vol.23
, pp. 1530-1538
-
-
Beltramo, M.1
Bernardini, N.2
Bertorelli, R.3
Campanella, M.4
Nicolussi, E.5
Fredduzzi, S.6
Reggiani, A.7
-
7
-
-
53549090175
-
Ultrastructural localization of neuronal brain CB2 cannabinoid receptors
-
Brusco, A.; Tagliaferro, P.A.; Saez, T.; Onaivi, E.S. Ultrastructural localization of neuronal brain CB2 cannabinoid receptors. Ann. N. Y. Acad. Sci. 2008, 1139, 450-457.
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1139
, pp. 450-457
-
-
Brusco, A.1
Tagliaferro, P.A.2
Saez, T.3
Onaivi, E.S.4
-
8
-
-
32844465920
-
Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain
-
Gong, J.P.; Onaivi, E.S.; Ishiguro, H.; Liu, Q.R.; Tagliaferro, P.A.; Brusco, A.; Uhl, G.R. Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Res. 2006 3, 10-23.
-
(2006)
Brain Res
, vol.3
, pp. 10-23
-
-
Gong, J.P.1
Onaivi, E.S.2
Ishiguro, H.3
Liu, Q.R.4
Tagliaferro, P.A.5
Brusco, A.6
Uhl, G.R.7
-
9
-
-
0035218154
-
Actions of cannabinoid receptor ligands on rat cultured sensory neurones: Implications for antinociception
-
Ross, R.A.; Coutts, A.A.; McFarlane, S.M.; Anavi-Goffer, S.; Irving, A.J.; Pertwee, R.G.; MacEwan, D.J.; Scott, R.H. Actions of cannabinoid receptor ligands on rat cultured sensory neurones: implications for antinociception. Neuropharmacology 2001, 40, 221-232.
-
(2001)
Neuropharmacology
, vol.40
, pp. 221-232
-
-
Ross, R.A.1
Coutts, A.A.2
McFarlane, S.M.3
Anavi-Goffer, S.4
Irving, A.J.5
Pertwee, R.G.6
Macewan, D.J.7
Scott, R.H.8
-
10
-
-
26844504226
-
Identification and functional characterization of brainstem cannabinoid CB2 receptors
-
Van Sickle, M.D.; Duncan, M.; Kingsley, P.J.; Mouihate, A.; Urbani, P.; Mackie, K.; Stella, N.; Makriyannis, A.; Piomelli, D.; Davison, J.S.; Marnett, L.J.; Di Marzo, V.; Pittman, Q.J.; Patel, K.D.; Sharkey, K.A. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 2005, 14, 329-332.
-
(2005)
Science
, vol.14
, pp. 329-332
-
-
van Sickle, M.D.1
Duncan, M.2
Kingsley, P.J.3
Mouihate, A.4
Urbani, P.5
Mackie, K.6
Stella, N.7
Makriyannis, A.8
Piomelli, D.9
Davison, J.S.10
Marnett, L.J.11
di Marzo, V.12
Pittman, Q.J.13
Patel, K.D.14
Sharkey, K.A.15
-
11
-
-
24044458606
-
Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons
-
Wotherspoon, G.; Fox, A.; McIntyre, P.; Colley, S.; Bevan, S.; Winter, J. Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons. Neuroscience 2005, 135, 235-245.
-
(2005)
Neuroscience
, vol.135
, pp. 235-245
-
-
Wotherspoon, G.1
Fox, A.2
McIntyre, P.3
Colley, S.4
Bevan, S.5
Winter, J.6
-
12
-
-
75849131456
-
Signal transduction via cannabinoid receptors
-
Dalton, G.D; Bass, C.E.; Van Horn, C.G.; Howlett, A.C.; Signal transduction via cannabinoid receptors. CNS Neurol. Disord. Drug Targets 2009, 8, 422-431.
-
(2009)
CNS Neurol. Disord. Drug Targets
, vol.8
, pp. 422-431
-
-
Dalton, G.D.1
Bass, C.E.2
van Horn, C.G.3
Howlett, A.C.4
-
13
-
-
21344432777
-
The endocannabinoid system: A drug discovery perspective
-
Piomelli, D. The endocannabinoid system: a drug discovery perspective. Curr. Opin. Investig. Drugs 2005, 6, 672-679.
-
(2005)
Curr. Opin. Investig. Drugs
, vol.6
, pp. 672-679
-
-
Piomelli, D.1
-
14
-
-
44849141696
-
Enzymatic pathways that regulate endocannabinoid signalling in the nervous system
-
Ahn, K.; McKinney, M.K.; Cravatt, B.F. Enzymatic pathways that regulate endocannabinoid signalling in the nervous system. Chem. Rev. 2008, 108, 1687-1707.
-
(2008)
Chem. Rev.
, vol.108
, pp. 1687-1707
-
-
Ahn, K.1
McKinney, M.K.2
Cravatt, B.F.3
-
15
-
-
10744229235
-
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain
-
Bisogno, T.; Howell, F.; Williams, G.; Minassi, A.; Cascio, M.G., Ligresti, A.; Matias, I., Schiano-Moriello, A.; Paul, P.; Williams, E.J.; Gangadharan, U.; Hobbs, C.; Di Marzo, V.; Doherty, P. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J. Cell Biol. 2003, 163, 463-468.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 463-468
-
-
Bisogno, T.1
Howell, F.2
Williams, G.3
Minassi, A.4
Cascio, M.G.5
Ligresti, A.6
Matias, I.7
Schiano-Moriello, A.8
Paul, P.9
Williams, E.J.10
Gangadharan, U.11
Hobbs, C.12
di Marzo, V.13
Doherty, P.14
-
16
-
-
0037661996
-
Role of endogenous cannabinoids in synaptic signaling
-
Freund, T.F.; Katona, I.; Piomelli, D. Role of endogenous cannabinoids in synaptic signaling. Physiol. Rev. 2003, 83, 1017-1066.
-
(2003)
Physiol. Rev.
, vol.83
, pp. 1017-1066
-
-
Freund, T.F.1
Katona, I.2
Piomelli, D.3
-
17
-
-
0033998951
-
Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol
-
Hillard, C.J. Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostaglandins Other. Lipid. Mediat. 2000, 61, 3-18.
-
(2000)
Prostaglandins Other. Lipid. Mediat.
, vol.61
, pp. 3-18
-
-
Hillard, C.J.1
-
18
-
-
68149165608
-
Treatment options for recurrent glioblastoma: Pitfalls and future trends
-
Franceschi, E.; Tosoni, A.; Bartolini, S.; Mazzocchi, V.; Fioravanti, A.; Brandes, A.A. Treatment options for recurrent glioblastoma: pitfalls and future trends. Expert Rev. Anticancer Ther. 2009, 5, 613-619.
-
(2009)
Expert Rev. Anticancer Ther.
, vol.5
, pp. 613-619
-
-
Franceschi, E.1
Tosoni, A.2
Bartolini, S.3
Mazzocchi, V.4
Fioravanti, A.5
Brandes, A.A.6
-
19
-
-
37449010247
-
Inhibition of angiogenesis and invasion in malignant gliomas
-
Chi A, Norden AD, Wen PY. Inhibition of angiogenesis and invasion in malignant gliomas. Expert Rev. Anticancer Ther. 2007, 7, 1537-1560.
-
(2007)
Expert Rev. Anticancer Ther.
, vol.7
, pp. 1537-1560
-
-
Chi, A.1
Norden, A.D.2
Wen, P.Y.3
-
20
-
-
34250803209
-
Molecularly targeted therapy for malignant glioma
-
Sathornsumetee, S.; Reardon, D.; Desjardins, A.; Quinn, J.A.; Vredenburgh, J.J.; Rich, J.N. Molecularly targeted therapy for malignant glioma. Cancer 2007, 110, 13-24.
-
(2007)
Cancer
, vol.110
, pp. 13-24
-
-
Sathornsumetee, S.1
Reardon, D.2
Desjardins, A.3
Quinn, J.A.4
Vredenburgh, J.J.5
Rich, J.N.6
-
21
-
-
23944445606
-
Neural stem cells and the origin of gliomas
-
Sanai, N.; Alvarez-Buylla, A.; Berger, M.S. Neural stem cells and the origin of gliomas. N. Engl. J. Med. 2005, 353, 811-822.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 811-822
-
-
Sanai, N.1
Alvarez-Buylla, A.2
Berger, M.S.3
-
22
-
-
32544460228
-
Novel immunotherapeutic approaches to glioma
-
Yamanaka, R. Novel immunotherapeutic approaches to glioma. Curr. Opin. Mol. Ther. 2006, 8, 46-51.
-
(2006)
Curr. Opin. Mol. Ther.
, vol.8
, pp. 46-51
-
-
Yamanaka, R.1
-
23
-
-
0032566430
-
Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells
-
Sánchez, C.; Galve-Roperh, I.; Canova, C.; Brachet, P.; Guzmán, M. Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells. FEBS Lett. 1998, 436, 6-10.
-
(1998)
FEBS Lett
, vol.436
, pp. 6-10
-
-
Sánchez, C.1
Galve-Roperh, I.2
Canova, C.3
Brachet, P.4
Guzmán, M.5
-
24
-
-
33645763253
-
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells
-
Carracedo, A.; Lorente, M.; Egia, A.; Blázquez, C.; García, S.; Giroux, V.; Malicet, C.; Villuendas, R.; Gironella, M.; González-Feria, L.; Piris, M.A.; Iovanna, J.L.; Guzmán, M.; Velasco, G. The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell 2006, 9, 301-312.
-
(2006)
Cancer Cell
, vol.9
, pp. 301-312
-
-
Carracedo, A.1
Lorente, M.2
Egia, A.3
Blázquez, C.4
García, S.5
Giroux, V.6
Malicet, C.7
Villuendas, R.8
Gironella, M.9
González-Feria, L.10
Piris, M.A.11
Iovanna, J.L.12
Guzmán, M.13
Velasco, G.14
-
25
-
-
33745929641
-
A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme
-
Guzmán, M.; Duarte, M.J.; Blázquez, C.; Ravina, J.; Rosa, M.C. Galve-Roperh, I.; Sánchez, C.; Velasco, G.; González-Feria, L. A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br. J. Cancer 2006, 95, 197-203.
-
(2006)
Br. J. Cancer
, vol.95
, pp. 197-203
-
-
Guzmán, M.1
Duarte, M.J.2
Blázquez, C.3
Ravina, J.4
Rosa, M.C.5
Galve-Roperh, I.6
Sánchez, C.7
Velasco, G.8
González-Feria, L.9
-
26
-
-
17344380844
-
Anti-tumoural action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
-
Galve-Roperh, I.; Sánchez, C.; Cortés, M.L.; Gomez del Pulgar, T.G.; Izquierdo, M.; Guzmán, M. Anti-tumoural action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat. Med. 2000, 6, 313-319.
-
(2000)
Nat. Med.
, vol.6
, pp. 313-319
-
-
Galve-Roperh, I.1
Sánchez, C.2
Cortés, M.L.3
del Gomez Pulgar, T.G.4
Izquierdo, M.5
Guzmán, M.6
-
27
-
-
4644331847
-
Cannabinoid physiology and pharmacology: 30 years of progress
-
Howlett, A.C.; Breivogel, C.S.; Childers, S.R.; Deadwyler, S.A.; Hampson, R.E.; Porrino, L.J. Cannabinoid physiology and pharmacology: 30 years of progress. Neuropharmacology 2004, 47, 345-358.
-
(2004)
Neuropharmacology
, vol.47
, pp. 345-358
-
-
Howlett, A.C.1
Breivogel, C.S.2
Childers, S.R.3
Deadwyler, S.A.4
Hampson, R.E.5
Porrino, L.J.6
-
28
-
-
84884474728
-
Pharmacological actions of cannabinoids
-
Pertwee, R. Pharmacological actions of cannabinoids. Handb. Exp. Pharmacol. 2005, 168, 1-51.
-
(2005)
Handb. Exp. Pharmacol.
, vol.168
, pp. 1-51
-
-
Pertwee, R.1
-
29
-
-
0035422139
-
Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor
-
Sánchez, C.; de Ceballos, M.L.; del Pulgar, T.G.; Rueda, D.; Corbacho, C.; Velasco, G.; Galve-Roperh, I.; Huffman, J.W.; Ramón y Cajal, S.; Guzmán, M. Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor. Cancer Res. 2001, 61, 5784-5789.
-
(2001)
Cancer Res
, vol.61
, pp. 5784-5789
-
-
Sánchez, C.1
de Ceballos, M.L.2
del Pulgar, T.G.3
Rueda, D.4
Corbacho, C.5
Velasco, G.6
Galve-Roperh, I.7
Huffman, J.W.8
-
30
-
-
33846921353
-
Distinctive pattern of cannabinoid receptor type II (CB2) expression in adult and pediatric brain tumours
-
Ellert-Miklaszewska, A.; Grajkowska, W.; Gabrusiewicz, K.; Kaminska, B.; Konarska, L. Distinctive pattern of cannabinoid receptor type II (CB2) expression in adult and pediatric brain tumours. Brain Res. 2007, 1137, 161-169.
-
(2007)
Brain Res
, vol.1137
, pp. 161-169
-
-
Ellert-Miklaszewska, A.1
Grajkowska, W.2
Gabrusiewicz, K.3
Kaminska, B.4
Konarska, L.5
-
31
-
-
38049025796
-
Expression of cannabinoid receptors and neurotrophins in human gliomas
-
Calatozzolo, C.; Salmaggi, A.; Pollo, B.; Sciacca, F.L.; Lorenzetti, M.; Franzini, A.; Boiardi, A.; Brogli, G.; Marras, C. Expression of cannabinoid receptors and neurotrophins in human gliomas. Neurol. Sci. 2007, 28, 304-310.
-
(2007)
Neurol. Sci.
, vol.28
, pp. 304-310
-
-
Calatozzolo, C.1
Salmaggi, A.2
Pollo, B.3
Sciacca, F.L.4
Lorenzetti, M.5
Franzini, A.6
Boiardi, A.7
Brogli, G.8
Marras, C.9
-
32
-
-
67349101287
-
Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans
-
Schley, M.; Ständer, S.; Kerner, J.; Vajkoczy, P.; Schüpfer, G.; Dusch, M.; Schmelz, M.; Konrad, C. Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans. Brain Res. Bull. 2009, 79, 333-337.
-
(2009)
Brain Res. Bull.
, vol.79
, pp. 333-337
-
-
Schley, M.1
Ständer, S.2
Kerner, J.3
Vajkoczy, P.4
Schüpfer, G.5
Dusch, M.6
Schmelz, M.7
Konrad, C.8
-
33
-
-
33747835307
-
Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma
-
Duntsch, C.; Divi, M.K.; Jones, T.; Zhou, Q.; Krishnamurthy, M.; Boehm, P.; Wood, G.; Sills, A.; Moore, B.M. Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. J. Neurooncol. 2006, 77, 143-52.
-
(2006)
J. Neurooncol.
, vol.77
, pp. 143-152
-
-
Duntsch, C.1
Divi, M.K.2
Jones, T.3
Zhou, Q.4
Krishnamurthy, M.5
Boehm, P.6
Wood, G.7
Sills, A.8
Moore, B.M.9
-
34
-
-
44849139287
-
Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs
-
Krishnamurthy, M.; Gurley, S.; Moore, B.M.II. Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs. Bioorg. Med. Chem. 2008, 16, 6489-6500.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 6489-6500
-
-
Krishnamurthy, M.1
Gurley, S.2
Moore, B.M.I.I.3
-
35
-
-
34250323489
-
Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis
-
Aguado, T.; Carracedo, A.; Julien, B.; Velasco, G.; Milman, G.; Mechoulam, R.; Alvarez, L.; Guzmán, M.; Galve-Roperh, I. Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis. J. Biol. Chem. 2007, 282, 6854-6862.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 6854-6862
-
-
Aguado, T.1
Carracedo, A.2
Julien, B.3
Velasco, G.4
Milman, G.5
Mechoulam, R.6
Alvarez, L.7
Guzmán, M.8
Galve-Roperh, I.9
-
36
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
A.C.; Barth, F.; Bonner, T.I.; Cabral, G.; Casellas, P.; Devane, W.A.; Felder, C.C.; Herkenham, M.; Mackie, K.; Martin, B.R.; Mechoulam, R.; Pertwee, R.G. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol. Rev. 2002, 54, 161-202.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 161-202
-
-
-
37
-
-
1342280974
-
Antitumour effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines
-
Massi, P.; Vaccani, A.; Ceruti, S.; Colombo, A.; Abbracchio, M.P.; Parolaro, D. Antitumour effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. J. Pharmacol. Exp. Ther. 2004, 308, 838-845.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 838-845
-
-
Massi, P.1
Vaccani, A.2
Ceruti, S.3
Colombo, A.4
Abbracchio, M.P.5
Parolaro, D.6
-
38
-
-
0034751335
-
Molecular targets for cannabidiol and its synthetic analogues: Effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
-
Bisogno, T.; Hanus, L.; De Petrocellis, L.; Tchilibon, S.; Ponde, D.E.; Brandi, I.; Moriello, A.S.; Davis, J.B.; Mechoulam, R.; Di Marzo, V. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br. J. Pharmacol. 2001, 134, 845-852
-
(2001)
Br. J. Pharmacol.
, vol.134
, pp. 845-852
-
-
Bisogno, T.1
Hanus, L.2
de Petrocellis, L.3
Tchilibon, S.4
Ponde, D.E.5
Brandi, I.6
Moriello, A.S.7
Davis, J.B.8
Mechoulam, R.9
di Marzo, V.10
-
39
-
-
33747624175
-
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
-
Ligresti, A.; Morello, A.S.; Starowicz, K.; Matias, I.; Pisanti, S.; De Petrocellis, L.; Laezza, C.; Portella, G.; Bifulco, M.; Di Marzo, V. Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. J. Pharmacol. Exp. Ther. 2006, 318, 375-387.
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.318
, pp. 375-387
-
-
Ligresti, A.1
Morello, A.S.2
Starowicz, K.3
Matias, I.4
Pisanti, S.5
de Petrocellis, L.6
Laezza, C.7
Portella, G.8
Bifulco, M.9
di Marzo, V.10
-
40
-
-
0034644769
-
Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors
-
Maccarrone, M.; Lorenzon, T.; Bari, M.; Melino, G.; Finazzi-Agrò, A. Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. J. Biol. Chem. 2000, 275, 31938-31945.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31938-31945
-
-
Maccarrone, M.1
Lorenzon, T.2
Bari, M.3
Melino, G.4
Finazzi-Agrò, A.5
-
41
-
-
44249117614
-
Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8
-
De Petrocellis, L.; Vellani, V.; Schiano-Moriello, A.; Marini, P.; Magherini, P.C.; Orlando, P.; Di Marzo, V. Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. J. Pharmacol. Exp. Ther. 2008, 325, 1007-1015.
-
(2008)
J. Pharmacol. Exp. Ther.
, vol.325
, pp. 1007-1015
-
-
de Petrocellis, L.1
Vellani, V.2
Schiano-Moriello, A.3
Marini, P.4
Magherini, P.C.5
Orlando, P.6
di Marzo, V.7
-
42
-
-
73949139182
-
Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival
-
Marcu, J.P.; Christian, R.T.; Lau, D.; Zielinski, A.J.; Horowitz, M.P.; Lee, J.; Pakdel, A.; Allison, J.; Limbad, C.; Moore, D.H.; Yount, G.L.; Desprez, P.Y.; McAllister, S.D. Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival. Mol. Cancer Ther. 2010, 9, 180-189.
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 180-189
-
-
Marcu, J.P.1
Christian, R.T.2
Lau, D.3
Zielinski, A.J.4
Horowitz, M.P.5
Lee, J.6
Pakdel, A.7
Allison, J.8
Limbad, C.9
Moore, D.H.10
Yount, G.L.11
Desprez, P.Y.12
McAllister, S.D.13
-
43
-
-
0035885205
-
Antitumour effects of ajulemic acid (CT3), a synthetic non-psychoactive cannabinoid
-
Recht, L.D.; Salmonsen, R.; Rosetti, R.; Jang, T.; Pipia, G.; Kubiatowski, T.; Karim, P.; Ross, A.H.; Zurier, R.; Litofsky, N.S.; Burstein, S. Antitumour effects of ajulemic acid (CT3), a synthetic non-psychoactive cannabinoid. Biochem. Pharmacol. 2001, 62, 755-763.
-
(2001)
Biochem. Pharmacol.
, vol.62
, pp. 755-763
-
-
Recht, L.D.1
Salmonsen, R.2
Rosetti, R.3
Jang, T.4
Pipia, G.5
Kubiatowski, T.6
Karim, P.7
Ross, A.H.8
Zurier, R.9
Litofsky, N.S.10
Burstein, S.11
-
44
-
-
33748703859
-
The endocannabinoid system as an emerging target of pharmacotherapy
-
Pacher, P.; Bátkai, S.; Kunos, G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol. Rev. 2006, 58, 389-462.
-
(2006)
Pharmacol. Rev.
, vol.58
, pp. 389-462
-
-
Pacher, P.1
Bátkai, S.2
Kunos, G.3
-
45
-
-
67449119913
-
The endocannabinoid system: Its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation
-
Di Marzo, V. The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation. Pharmacol. Res. 2009, 60, 77-84.
-
(2009)
Pharmacol. Res.
, vol.60
, pp. 77-84
-
-
di Marzo, V.1
-
46
-
-
0035200613
-
Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors
-
Jacobsson, S.O.; Wallin, T.; Fowler, C.J. Inhibition of rat C6 glioma cell proliferation by endogenous and synthetic cannabinoids. Relative involvement of cannabinoid and vanilloid receptors. J. Pharmacol. Exp. Ther. 2001, 299, 951-959.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 951-959
-
-
Jacobsson, S.O.1
Wallin, T.2
Fowler, C.J.3
-
47
-
-
0037103724
-
Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells
-
Maccarrone, M.; Pauselli, R.; Di Rienzo, M.; Finazzi-Agrò, A. Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells. Biochem. J. 2002, 366, 137-144.
-
(2002)
Biochem. J.
, vol.366
, pp. 137-144
-
-
Maccarrone, M.1
Pauselli, R.2
di Rienzo, M.3
Finazzi-Agrò, A.4
-
48
-
-
4444310096
-
Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1
-
Contassot, E.; Wilmotte, R.; Tenan, M.; Belkouch, M.C.; Schnüriger, V.; de Tribolet, N.; Burkhardt, K.; Dietrich, P.Y. Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1. J. Neuropathol. Exp. Neurol. 2004, 63, 956-963.
-
(2004)
J. Neuropathol. Exp. Neurol.
, vol.63
, pp. 956-963
-
-
Contassot, E.1
Wilmotte, R.2
Tenan, M.3
Belkouch, M.C.4
Schnüriger, V.5
de Tribolet, N.6
Burkhardt, K.7
Dietrich, P.Y.8
-
49
-
-
33749182829
-
Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations
-
De Lago, E.; Gustafsson, S.B.; Fernández-Ruiz, J.; Nilsson, J.; Jacobsson, S.O.; Fowler, C.J. Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. J. Neurochem. 2006, 99, 677-688.
-
(2006)
J. Neurochem.
, vol.99
, pp. 677-688
-
-
de Lago, E.1
Gustafsson, S.B.2
Fernández-Ruiz, J.3
Nilsson, J.4
Jacobsson, S.O.5
Fowler, C.J.6
-
50
-
-
0035147072
-
Ceramide: A new second messenger of cannabinoid action
-
Guzman, M.; Galve-Roperh, I.; Sanchez, C. Ceramide: a new second messenger of cannabinoid action. Trends Pharmacol. Sci. 2001, 22, 19-22.
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 19-22
-
-
Guzman, M.1
Galve-Roperh, I.2
Sanchez, C.3
-
51
-
-
17344380844
-
Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
-
Galve-Roperh, I.; Sanchez, C.; Cortes, M. L.; Gomez del Pulgar, T., Izquierdo, M.; Guzman, M. Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat. Med. 2000, 6, 313-319.
-
(2000)
Nat. Med.
, vol.6
, pp. 313-319
-
-
Galve-Roperh, I.1
Sanchez, C.2
Cortes, M.L.3
del Gomez Pulgar, T.4
Izquierdo, M.5
Guzman, M.6
-
52
-
-
0033806918
-
The CB1 cannabinoid receptor is coupled to the activation of c-Jun N-terminal kinase
-
Rueda, D.; Galve-Roperh, I.; Haro, A.; Guzman, M. The CB1 cannabinoid receptor is coupled to the activation of c-Jun N-terminal kinase. Mol. Pharmacol. 2000, 58, 814-820.
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 814-820
-
-
Rueda, D.1
Galve-Roperh, I.2
Haro, A.3
Guzman, M.4
-
53
-
-
0035049233
-
Tetrahydrocannabinol-induced apoptosis of cultured cortical neurones is associated with cytochrome c release and caspase-3 activation
-
Campbell, V. A. Tetrahydrocannabinol-induced apoptosis of cultured cortical neurones is associated with cytochrome c release and caspase-3 activation. Neuropharmacology 2001, 40: 702-709.
-
(2001)
Neuropharmacology
, vol.40
, pp. 702-709
-
-
Campbell, V.A.1
-
54
-
-
0032527129
-
Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol
-
Chan, G.C.; Hinds, T.R.; Impey, S.; Storm, D.R. Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol. J. Neurosci. 1998, 18, 5322-5332.
-
(1998)
J. Neurosci.
, vol.18
, pp. 5322-5332
-
-
Chan, G.C.1
Hinds, T.R.2
Impey, S.3
Storm, D.R.4
-
55
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
Salazar, M.; Carracedo, A.; Salanueva, I.J.; Hernández-Tiedra, S.; Lorente, M.; Egia, A.; Vázquez, P.; Blázquez, C.; Torres, S.; García, S.; Nowak, J.; Fimia, G.M.; Piacentini, M.; Cecconi, F.; Pandolfi, P.P.; González-Feria, L.; Iovanna, J.L.; Guzmán, M.; Boya, P.; Velasco, G.; Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J. Clin. Invest. 2009, 119, 1359-1372.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernández-Tiedra, S.4
Lorente, M.5
Egia, A.6
Vázquez, P.7
Blázquez, C.8
Torres, S.9
García, S.10
Nowak, J.11
Fimia, G.M.12
Piacentini, M.13
Cecconi, F.14
Pandolfi, P.P.15
González-Feria, L.16
Iovanna, J.L.17
Guzmán, M.18
Boya, P.19
Velasco, G.20
more..
-
56
-
-
1342280974
-
Antitumour effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines
-
P,; Vaccani, A.; Ceruti, S.; Colombo, A.; Abbracchio, M.P.; Parolaro, D. Antitumour effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines. J. Pharmacol. Exp. Ther. 2004, 308, 838-845.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 838-845
-
-
-
57
-
-
4644226099
-
Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein
-
Ellert-Miklaszewska, A.; Kaminska, B.; Konarska, L. Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein. Cell Signal. 2005, 17, 25-37.
-
(2005)
Cell Signal
, vol.17
, pp. 25-37
-
-
Ellert-Miklaszewska, A.1
Kaminska, B.2
Konarska, L.3
-
58
-
-
0034654660
-
The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt
-
Gomez del Pulgar, T.; Velasco, G.; Guzman, M. The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. Biochem. J. 2000, 347, 369-373.
-
(2000)
Biochem. J.
, vol.347
, pp. 369-373
-
-
Gomez del Pulgar, T.1
Velasco, G.2
Guzman, M.3
-
59
-
-
38449109178
-
5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid
-
Massi, P.; Valenti, M.; Vaccani, A:, Gasperi, V:, Perletti, G.; Marras, E.; Fezza, F.; Maccarrone, M.; Parolaro, D. 5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. J. Neurochem. 2008, 104, 1091-1100.
-
(2008)
J. Neurochem.
, vol.104
, pp. 1091-1100
-
-
Massi, P.1
Valenti, M.2
Vaccani, A.3
Gasperi, V.4
Perletti, G.5
Marras, E.6
Fezza, F.7
Maccarrone, M.8
Parolaro, D.9
-
60
-
-
23444431657
-
Delta9-tetrahydrocannabinol increases C6 glioma cell death produced by oxidative stress
-
Goncharov, I.; Weiner, L.; Vogel, Z. Delta9-tetrahydrocannabinol increases C6 glioma cell death produced by oxidative stress. Neuroscience 2005, 134, 567-574.
-
(2005)
Neuroscience
, vol.134
, pp. 567-574
-
-
Goncharov, I.1
Weiner, L.2
Vogel, Z.3
-
61
-
-
33748492117
-
The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells
-
Massi, P.; Vaccani, A.; Bianchessi, S.; Costa, B.; Macchi, P.; Parolaro, D. The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. Cell Mol. Life Sci. 2006, 63, 2057-2066.
-
(2006)
Cell Mol. Life Sci.
, vol.63
, pp. 2057-2066
-
-
Massi, P.1
Vaccani, A.2
Bianchessi, S.3
Costa, B.4
Macchi, P.5
Parolaro, D.6
-
62
-
-
41149153235
-
A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells
-
Lee, C.Y.; Wey, S.P.; Liao, M.H.; Hsu, W.L.; Wu, H.Y.; Jan, T.R. A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells. Int. Immunopharmacol. 2008, 8, 732-740.
-
(2008)
Int. Immunopharmacol.
, vol.8
, pp. 732-740
-
-
Lee, C.Y.1
Wey, S.P.2
Liao, M.H.3
Hsu, W.L.4
Wu, H.Y.5
Jan, T.R.6
-
63
-
-
67651151234
-
Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism
-
Gustafsson, K.; Sander, B.; Bielawski, J.; Hannun, Y.A.; Flygare, J. Potentiation of cannabinoid-induced cytotoxicity in mantle cell lymphoma through modulation of ceramide metabolism. Mol. Cancer Res. 2009, 7, 1086-1098.
-
(2009)
Mol. Cancer Res.
, vol.7
, pp. 1086-1098
-
-
Gustafsson, K.1
Sander, B.2
Bielawski, J.3
Hannun, Y.A.4
Flygare, J.5
-
64
-
-
0034696960
-
Anandamide induces apoptosis of PC-12 cells: Involvement of superoxide and caspase-3
-
Sarker, K.P.; Obara, S.; Nakata, M.; Kitajima, I.; Maruyama, I. Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. FEBS Lett. 2000, 472, 39-44.
-
(2000)
FEBS Lett
, vol.472
, pp. 39-44
-
-
Sarker, K.P.1
Obara, S.2
Nakata, M.3
Kitajima, I.4
Maruyama, I.5
|