-
1
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI: Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature (1990) 346(6284):561-564.
-
(1990)
Nature
, vol.346
, Issue.6284
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
3
-
-
0037661996
-
Role of endogenous cannabinoids in synaptic signaling
-
Freund T, Katona I, Piomelli D: Role of endogenous cannabinoids in synaptic signaling. Physiol Rev (2003) 83(3):1017-1066.
-
(2003)
Physiol. Rev.
, vol.83
, Issue.3
, pp. 1017-1066
-
-
Freund, T.1
Katona, I.2
Piomelli, D.3
-
4
-
-
0242268553
-
The molecular logic of endocannabinoid signalling
-
Piomelli D: The molecular logic of endocannabinoid signalling. Nat Rev Neurosci (2003) 4(11):873-884.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, Issue.11
, pp. 873-884
-
-
Piomelli, D.1
-
5
-
-
0037207080
-
The quest for a vascular endothelial cannabinold receptor
-
Kunos G, Batkai S, Offertaler L, Mo F, Liu J, Karcher J, Harvey-White J: The quest for a vascular endothelial cannabinold receptor. Chem Phys Lipids (2002) 121(1-2):45-56.
-
(2002)
Chem. Phys. Lipids
, vol.121
, Issue.1-2
, pp. 45-56
-
-
Kunos, G.1
Batkai, S.2
Offertaler, L.3
Mo, F.4
Liu, J.5
Karcher, J.6
Harvey-White, J.7
-
7
-
-
0028129936
-
SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
-
Rinaldi-Carmona M, Barth F, Heaulme M, Shire D, Calandra B, Congy C, Martinez S, Maruani J, Neliat G, Caput D, Ferrara P et al: SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett (1994) 350(2-3):240-244.
-
(1994)
FEBS Lett.
, vol.350
, Issue.2-3
, pp. 240-244
-
-
Rinaldi-Carmona, M.1
Barth, F.2
Heaulme, M.3
Shire, D.4
Calandra, B.5
Congy, C.6
Martinez, S.7
Maruani, J.8
Neliat, G.9
Caput, D.10
Ferrara, P.11
-
8
-
-
0032517566
-
Adverse effects of cannabis
-
Hall W, Solowij N: Adverse effects of cannabis. Lancet (1998) 352(9140):1611-1616.
-
(1998)
Lancet
, vol.352
, Issue.9140
, pp. 1611-1616
-
-
Hall, W.1
Solowij, N.2
-
9
-
-
0032914945
-
2 function
-
2 function. Neuroscience (1999) 91(2):607-620.
-
(1999)
Neuroscience
, vol.91
, Issue.2
, pp. 607-620
-
-
Alonso, R.1
Voutsinos, B.2
Fournier, M.3
Labie, C.4
Steinberg, R.5
Souilhac, J.6
Le Fur, G.7
Soubrié, P.8
-
10
-
-
0033362973
-
Dopamine activation of endogenous cannabinoid signaling in dorsal striatum
-
Giuffrida A, Parsons LH, Kerr TM, Rodríguez de Fonseca F, Navarro M, Piomelli D: Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. Nat Neurosci (1999) 2(4):358-363.
-
(1999)
Nat. Neurosci.
, vol.2
, Issue.4
, pp. 358-363
-
-
Giuffrida, A.1
Parsons, L.H.2
Kerr, T.M.3
Rodríguez de Fonseca, F.4
Navarro, M.5
Piomelli, D.6
-
11
-
-
0037221846
-
Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in rat
-
Martin RS, Secchi RL, Lemaire M, Bonhaus DW, Hedley LR, Lowe DA: Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in rat. Psychopharmacology (2003) 165(2):128-135.
-
(2003)
Psychopharmacology
, vol.165
, Issue.2
, pp. 128-135
-
-
Martin, R.S.1
Secchi, R.L.2
Lemaire, M.3
Bonhaus, D.W.4
Hedley, L.R.5
Lowe, D.A.6
-
12
-
-
2942538034
-
Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder
-
Meltzer H, Arvanitis L, Bauer D, Rein W: Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder. Am J Psychiatry (2004) 161(6):975-984.
-
(2004)
Am. J. Psychiatry
, vol.161
, Issue.6
, pp. 975-984
-
-
Meltzer, H.1
Arvanitis, L.2
Bauer, D.3
Rein, W.4
-
13
-
-
0032541111
-
Appetite suppression and weight loss after the cannabinoid antagonist SR141716
-
Colombo G, Agabio R, Diaz G, Lobina C, Reali R, Gessa GL: Appetite suppression and weight loss after the cannabinoid antagonist SR141716. Life Sci (1998) 63(8):PL113-PL117.
-
(1998)
Life Sci.
, vol.63
, Issue.8
-
-
Colombo, G.1
Agabio, R.2
Diaz, G.3
Lobina, C.4
Reali, R.5
Gessa, G.L.6
-
14
-
-
0031902759
-
1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset
-
1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset. Behav Pharmacol (1998) 9(2):179-181.
-
(1998)
Behav. Pharmacol.
, vol.9
, Issue.2
, pp. 179-181
-
-
Simiand, J.1
Keane, M.2
Keane, P.E.3
Soubrié, P.4
-
15
-
-
0035848818
-
Leptin-regulated endocannabinoids are involved in maintaining food intake
-
Di Marzo V, Golparaju SK, Wang L, Liu J, Batkai S, Jarai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, Kunos G: Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature (2001) 410(6830):822-825.
-
(2001)
Nature
, vol.410
, Issue.6830
, pp. 822-825
-
-
Di Marzo, V.1
Golparaju, S.K.2
Wang, L.3
Liu, J.4
Batkai, S.5
Jarai, Z.6
Fezza, F.7
Miura, G.I.8
Palmiter, R.D.9
Sugiura, T.10
Kunos, G.11
-
16
-
-
21344441597
-
Drugs in Development. sanofi-aventis has released more positive data for Acomplia
-
www.diabetes in control.com, USA November 16
-
Drugs in Development. sanofi-aventis has released more positive data for Acomplia: www. diabetes in control.com, USA (2004): November 16. http://www.diabetesincontrol.com/modules.php?name=News&file= article&sid=2238
-
(2004)
-
-
-
18
-
-
33947267195
-
1 selective cannabinoid antagonist AM281: A potential human SPECT ligand
-
1 selective cannabinoid antagonist AM281: A potential human SPECT ligand. AAPS Pharmsci (1999) 1(2):E4.
-
(1999)
AAPS Pharmsci.
, vol.1
, Issue.2
-
-
Lan, R.1
Gatley, J.2
Lu, Q.3
Fan, P.4
Fernando, S.R.5
Volkow, N.D.6
Pertwee, R.7
Makriyannis, A.8
-
19
-
-
9144260517
-
1 cannabinold receptor antagonists
-
1 cannabinold receptor antagonists. J Med Chem (2004) 47(3):627-643.
-
(2004)
J. Med. Chem.
, vol.47
, Issue.3
, pp. 627-643
-
-
Lange, J.1
Coolen, H.K.2
van Stuivenberg, H.H.3
Dijksman, J.A.4
Herremans, A.H.5
Ronken, E.6
Keizer, H.G.7
Tipker, K.8
McCreary, A.C.9
Veerman, W.10
Wals, H.C.11
-
20
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG: Central nervous system control of food intake. Nature (2000) 404(6778):661-671.
-
(2000)
Nature
, vol.404
, Issue.6778
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
21
-
-
14344259844
-
1 receptor antagonists as promising new medications for drug dependence
-
1 receptor antagonists as promising new medications for drug dependence. J Pharmacol Exp Ther (2005) 312(3):875-883.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.312
, Issue.3
, pp. 875-883
-
-
Le Foll, B.1
Goldberg, S.R.2
-
22
-
-
85047690626
-
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
Cota D, Marsicano G, Tschop M, Grubler Y, Flachskamm C, Schubert M, Auer D, Yassouridis A, Thone-Reineke C, Ortmann S, Tomassoni F et al: The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest (2003) 112(3):423-431.
-
(2003)
J. Clin. Invest.
, vol.112
, Issue.3
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschop, M.3
Grubler, Y.4
Flachskamm, C.5
Schubert, M.6
Auer, D.7
Yassouridis, A.8
Thone-Reineke, C.9
Ortmann, S.10
Tomassoni, F.11
-
24
-
-
0036849961
-
1 cannabinoid receptor-dependent modulation of feeding
-
1 cannabinoid receptor-dependent modulation of feeding. J Neurosci (2002) 22(21):9612-9617.
-
(2002)
J. Neurosci.
, vol.22
, Issue.21
, pp. 9612-9617
-
-
Gomez, R.1
Navarro, M.2
Ferrer, B.3
Trigo, J.M.4
Bilbao, A.5
Del Arco, I.6
Cipitelli, A.7
Nava, F.8
Piomelli, D.9
Rodriguez de Fonseca, F.10
-
26
-
-
13544253295
-
Calls for caution as obesity drug stirs up a whirlwind of hopes
-
December 5
-
Kolata G: Calls for caution as obesity drug stirs up a whirlwind of hopes. New York Times December 5 (2004):1.
-
(2004)
New York Times
, pp. 1
-
-
Kolata, G.1
-
27
-
-
0030609879
-
1 cannabinoid receptor antagonist SR141716A induces anxiety-like responses in the rat
-
1 cannabinoid receptor antagonist SR141716A induces anxiety-like responses in the rat. Neuroreport (1997) 8(2):491-496.
-
(1997)
Neuroreport
, vol.8
, Issue.2
, pp. 491-496
-
-
Navarro, M.1
Hernandez, E.2
Munoz, R.M.3
del Arco, I.4
Villanua, M.A.5
Carrera, M.R.6
Rodriguez de Fonseca, F.7
-
29
-
-
0032722267
-
1 cannabinoid receptor antagonist, potentiates the locomotor stimulant effects of amphetamine and apomorphine
-
1 cannabinoid receptor antagonist, potentiates the locomotor stimulant effects of amphetamine and apomorphine. Behav Pharmacol (1999) 10(4):429-432.
-
(1999)
Behav. Pharmacol.
, vol.10
, Issue.4
, pp. 429-432
-
-
Masserano, J.M.1
Karoum, F.2
Wyatt, R.J.3
-
30
-
-
0031773354
-
Cardiovascular actions of cannabinoids and their generation during shock
-
Wagner JA, Varga K, Kunos G: Cardiovascular actions of cannabinoids and their generation during shock. J Mol Med (1998) 76(12):824-836.
-
(1998)
J. Mol. Med.
, vol.76
, Issue.12
, pp. 824-836
-
-
Wagner, J.A.1
Varga, K.2
Kunos, G.3
-
31
-
-
20844454912
-
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
-
Batkai S, Pacher P, Osei-Hyiaman D, Radaeva S, Liu J, Harvey-White J, Offertaler L, Mackie K, Rudd MA, Bukoski RD, Kunos G: Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation (2004) 110(14):1996-2002.
-
(2004)
Circulation
, vol.110
, Issue.14
, pp. 1996-2002
-
-
Batkai, S.1
Pacher, P.2
Osei-Hyiaman, D.3
Radaeva, S.4
Liu, J.5
Harvey-White, J.6
Offertaler, L.7
Mackie, K.8
Rudd, M.A.9
Bukoski, R.D.10
Kunos, G.11
-
33
-
-
0037334206
-
Cannabis use for chronic non-cancer pain: Results of a prospective survey
-
Ware M, Doyle CR, Woods R, Lynch ME, Clark AJ: Cannabis use for chronic non-cancer pain: Results of a prospective survey. Pain (2003) 102(1-2):211-216.
-
(2003)
Pain
, vol.102
, Issue.1-2
, pp. 211-216
-
-
Ware, M.1
Doyle, C.R.2
Woods, R.3
Lynch, M.E.4
Clark, A.J.5
-
34
-
-
4043096916
-
Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial
-
Svendsen K, Jensen TS, Bach FW: Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial. Br Med J (2004) 329(7460):253.
-
(2004)
Br. Med. J.
, vol.329
, Issue.7460
, pp. 253
-
-
Svendsen, K.1
Jensen, T.S.2
Bach, F.W.3
-
35
-
-
1542284124
-
Are oral cannabinoids safe and effective in refractory neuropathic pain?
-
Attal N, Brasseur L, Guirimand D, Clermond-Gnamien S, Atlami S, Bouhassira D: Are oral cannabinoids safe and effective in refractory neuropathic pain? Eur J Pain (2004) 8(2):173-177.
-
(2004)
Eur. J. Pain
, vol.8
, Issue.2
, pp. 173-177
-
-
Attal, N.1
Brasseur, L.2
Guirimand, D.3
Clermond-Gnamien, S.4
Atlami, S.5
Bouhassira, D.6
-
36
-
-
0032537734
-
Control of pain initiation by endogenous cannabinoids
-
Calignano A, La Rana G, Giuffrida A, Piomelli D: Control of pain initiation by endogenous cannabinoids. Nature (1998) 394(6690):277-281.
-
(1998)
Nature
, vol.394
, Issue.6690
, pp. 277-281
-
-
Calignano, A.1
La Rana, G.2
Giuffrida, A.3
Piomelli, D.4
-
38
-
-
0037773461
-
The neuronal distribution of cannabinold receptor type 1 in the trigeminal ganglion of the rat
-
Price TJ, Helesic G, Parghi D, Hargreaves KM, Flores CM: The neuronal distribution of cannabinold receptor type 1 in the trigeminal ganglion of the rat. Neuroscience (2003) 120(1):155-162.
-
(2003)
Neuroscience
, vol.120
, Issue.1
, pp. 155-162
-
-
Price, T.J.1
Helesic, G.2
Parghi, D.3
Hargreaves, K.M.4
Flores, C.M.5
-
39
-
-
0038182182
-
Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridization and immunohistochemistry
-
Bridges D, Rice AS, Egertova M, Elphick MR, Winter J, Michael GJ: Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridization and immunohistochemistry. Neuroscience (2003) 119(3):803-812.
-
(2003)
Neuroscience
, vol.119
, Issue.3
, pp. 803-812
-
-
Bridges, D.1
Rice, A.S.2
Egertova, M.3
Elphick, M.R.4
Winter, J.5
Michael, G.J.6
-
40
-
-
1642276200
-
Dissecting out mechanisms responsible for peripheral neuropathic pain: Implications for diagnosis and therapy
-
Woolf C: Dissecting out mechanisms responsible for peripheral neuropathic pain: Implications for diagnosis and therapy. Life Sci (2004) 74(21):2605-2610.
-
(2004)
Life Sci.
, vol.74
, Issue.21
, pp. 2605-2610
-
-
Woolf, C.1
-
42
-
-
0032587227
-
9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: A peripheral cannabinoid action
-
9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: A peripheral cannabinoid action. Psychopharmacology (1999) 143(3):322-326.
-
(1999)
Psychopharmacology
, vol.143
, Issue.3
, pp. 322-326
-
-
Ko, M.C.1
Woods, J.H.2
-
43
-
-
0344405669
-
Cannabinoid agonists attenuate capsaicin-induced responses in human skin
-
Rukwied R, Watkinson A, McGlone F, Dvorak M: Cannabinoid agonists attenuate capsaicin-induced responses in human skin. Pain (2003) 102(3):283-288.
-
(2003)
Pain
, vol.102
, Issue.3
, pp. 283-288
-
-
Rukwied, R.1
Watkinson, A.2
McGlone, F.3
Dvorak, M.4
-
44
-
-
3042701554
-
Ajulemic acid: A novel cannabinoid produces analgesia without a "high"
-
Burstein SH, Karst M, Schneider U, Zurier RB: Ajulemic acid: A novel cannabinoid produces analgesia without a "high". Life Sci (2004) 75(12):1513-1522.
-
(2004)
Life Sci.
, vol.75
, Issue.12
, pp. 1513-1522
-
-
Burstein, S.H.1
Karst, M.2
Schneider, U.3
Zurier, R.B.4
-
45
-
-
0030756533
-
Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclase
-
Rhee MH, Vogel Z, Barg J, Bayewitch M, Levy R, Hanus L, Breuer A, Mechoulam R: Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclase. J Med Chem (1997) 40(20):3228-3233.
-
(1997)
J. Med. Chem.
, vol.40
, Issue.20
, pp. 3228-3233
-
-
Rhee, M.H.1
Vogel, Z.2
Barg, J.3
Bayewitch, M.4
Levy, R.5
Hanus, L.6
Breuer, A.7
Mechoulam, R.8
-
46
-
-
21344466205
-
Comparison of ajulemic acid and WIN-55,212-2 in models of neuropathic, inflammatory and acute pain
-
Abs 173.5
-
Gottshall S, Harrison J, Pearson M, Turchin P, Chaffer S, Whitehead J, Hachicha M, Walker K, Pomonis JD: Comparison of ajulemic acid and WIN-55,212-2 in models of neuropathic, inflammatory and acute pain. Abs Soc Neuroscience (2004) 34:Abs 173.5.
-
(2004)
Abs. Soc. Neuroscience
, vol.34
-
-
Gottshall, S.1
Harrison, J.2
Pearson, M.3
Turchin, P.4
Chaffer, S.5
Whitehead, J.6
Hachicha, M.7
Walker, K.8
Pomonis, J.D.9
-
47
-
-
0141593561
-
Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: A randomized controlled trial
-
Karst M, Salim K, Burstein S, Conrad I, Hoy L, Schneider U: Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: A randomized controlled trial. J Am Med Assoc (2003) 290(13):1757-1762.
-
(2003)
J. Am. Med. Assoc.
, vol.290
, Issue.13
, pp. 1757-1762
-
-
Karst, M.1
Salim, K.2
Burstein, S.3
Conrad, I.4
Hoy, L.5
Schneider, U.6
-
48
-
-
21344438058
-
Product pipeline
-
Indevus Pharmaceuticals Inc: Company Web Site www.indevus.com
-
Indevus Pharmaceuticals Inc: Product pipeline. Company Web Site (2005) www.indevus.com
-
(2005)
-
-
-
49
-
-
21344441823
-
Novartis R&D Day 2002: An innovative pipeline keeping the momentum
-
Company Presentation October 17
-
Novartis AG: Novartis R&D Day 2002: An innovative pipeline keeping the momentum. Company Presentation (2002): October 17.
-
(2002)
-
-
Novartis, A.G.1
-
50
-
-
21344451756
-
Clinical pipeline
-
Kadmus Pharmaceuticals Inc: Company Web Site
-
Kadmus Pharmaceuticals Inc: Clinical pipeline. Company Web Site (2004). http://www.kadmuspharma.com/pipeline.asp
-
(2004)
-
-
-
51
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S, Thomas KL, Abu-Shaar M: Molecular characterization of a peripheral receptor for cannabinoids. Nature (1993) 365(6441):61-65.
-
(1993)
Nature
, vol.365
, Issue.6441
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
52
-
-
0041836218
-
2 cannabinold receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS
-
2 cannabinold receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS. Proc Natl Acad Sci USA (2003) 100(18):10529-10533.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, Issue.18
, pp. 10529-10533
-
-
Ibrahim, M.1
Deng, H.2
Zvonolk, A.3
Cockayne, D.A.4
Kwan, J.5
Mata, H.P.6
Vanderah, T.W.7
Lai, J.8
Porreca, F.9
Makriyannis, A.10
Malan Jr., T.P.11
-
54
-
-
0038521050
-
2 receptors supresses spinal fos protein expression and pain behavior in a rat model of inflammation
-
2 receptors supresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience (2003) 119(3):747-757.
-
(2003)
Neuroscience
, vol.119
, Issue.3
, pp. 747-757
-
-
Nackley, A.G.1
Makriyannis, A.2
Hohmann, A.G.3
-
56
-
-
20144388149
-
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy
-
Valenzano K, Tafesse L, Lee G, Harrison JE, Boulet JM, Gottshall SL, Mark L, Pearson MS, Miller W, Shan S, Rabadi L et al: Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy. Neuropharmacology (2005) 48(5):658-672.
-
(2005)
Neuropharmacology
, vol.48
, Issue.5
, pp. 658-672
-
-
Valenzano, K.1
Tafesse, L.2
Lee, G.3
Harrison, J.E.4
Boulet, J.M.5
Gottshall, S.L.6
Mark, L.7
Pearson, M.S.8
Miller, W.9
Shan, S.10
Rabadi, L.11
-
57
-
-
12944263838
-
2, a peripheral cannabinoid receptor
-
2, a peripheral cannabinoid receptor. Proc Natl Acad Sci USA (1999) 96(25):14228-14233.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, Issue.25
, pp. 14228-14233
-
-
Hanus, L.1
Breuer, A.2
Tchilibon, S.3
Shiloah, S.4
Goldenberg, D.5
Horowitz, M.6
Pertwee, R.G.7
Mechoulam, R.8
Fride, E.9
-
58
-
-
21344448283
-
Pharmos Corporation; fact sheet January 2002
-
Company Brochure Pharmos Corp: January
-
Pharmos Corp: Pharmos Corporation; fact sheet January 2002. Company Brochure (2002): January.
-
(2002)
-
-
-
59
-
-
0030865871
-
Functional role of high-affinity anandamide transport, as revealed by selective inhibition
-
Beltramo M, Stella N, Calignano A, Lin SY, Makriyannis A, Piomelli D: Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science (1997) 277(5329):1094-1097.
-
(1997)
Science
, vol.277
, Issue.5329
, pp. 1094-1097
-
-
Beltramo, M.1
Stella, N.2
Calignano, A.3
Lin, S.Y.4
Makriyannis, A.5
Piomelli, D.6
-
60
-
-
2942525207
-
Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172
-
Fegley D, Kathuria S, Mercier R, Li C, Goutopoulos A, Makriyannis A, Piomelli D: Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. Proc Natl Acad Sci USA (2004) 101(23):8756-8761.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.23
, pp. 8756-8761
-
-
Fegley, D.1
Kathuria, S.2
Mercier, R.3
Li, C.4
Goutopoulos, A.5
Makriyannis, A.6
Piomelli, D.7
-
61
-
-
21344433571
-
A novel, potent, selective, non-endocannabinoid related inhibitor of anandamide inactivation demonstrates robust analgesic effects in an in vivo pain model
-
Abs 273.11
-
Porter A, Li J, Love PL, Shannon HE, Li DL, Phebus LA, Gleason SD, Witkin JM, Simmons RM, Iyengar S, Nomikos GG: A novel, potent, selective, non-endocannabinoid related inhibitor of anandamide inactivation demonstrates robust analgesic effects in an in vivo pain model. Abs Soc Neuroscience (2004) 34:Abs 273.11.
-
(2004)
Abs. Soc. Neuroscience
, vol.34
-
-
Porter, A.1
Li, J.2
Love, P.L.3
Shannon, H.E.4
Li, D.L.5
Phebus, L.A.6
Gleason, S.D.7
Witkin, J.M.8
Simmons, R.M.9
Iyengar, S.10
Nomikos, G.G.11
-
62
-
-
0042572380
-
Fatty acid amide hydrolase: An emerging therapeutic target in the endocannabinoid system
-
Cravatt BF, Lichtman AH: Fatty acid amide hydrolase: An emerging therapeutic target in the endocannabinoid system. Curr Opin Chem Biol (2003) 7(4):469-475.
-
(2003)
Curr. Opin. Chem. Biol.
, vol.7
, Issue.4
, pp. 469-475
-
-
Cravatt, B.F.1
Lichtman, A.H.2
-
63
-
-
0036678094
-
Brain monoglyceride lipase participating in endocannabinoid inactivation
-
Dinh TP, Carpenter D, Leslie FM, Freund TF, Katona I, Sensi SL, Kathuria S, Piomelli D: Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci USA (2002) 99(16):10819-10824.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.16
, pp. 10819-10824
-
-
Dinh, T.P.1
Carpenter, D.2
Leslie, F.M.3
Freund, T.F.4
Katona, I.5
Sensi, S.L.6
Kathuria, S.7
Piomelli, D.8
-
64
-
-
6944247598
-
RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol
-
Dinh T, Kathuria S, Piomelli D: RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol. Mol Pharmacol (2004) 66(5):1260-1264.
-
(2004)
Mol. Pharmacol.
, vol.66
, Issue.5
, pp. 1260-1264
-
-
Dinh, T.1
Kathuria, S.2
Piomelli, D.3
-
65
-
-
3242751838
-
Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala
-
Gulyas AI, Cravatt BF, Bracey MH, Dinh TP, Piomelli D, Boscia F, Freund TF: Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala. Eur J Neurosci (2004) 20(2):441-458.
-
(2004)
Eur. J. Neurosci.
, vol.20
, Issue.2
, pp. 441-458
-
-
Gulyas, A.I.1
Cravatt, B.F.2
Bracey, M.H.3
Dinh, T.P.4
Piomelli, D.5
Boscia, F.6
Freund, T.F.7
-
66
-
-
0035979244
-
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
-
Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Gjang DK, Martin BR, Lichtman AH: Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc Natl Acad Sci USA (2001) 98(16):9371-9376.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.16
, pp. 9371-9376
-
-
Cravatt, B.F.1
Demarest, K.2
Patricelli, M.P.3
Bracey, M.H.4
Gjang, D.K.5
Martin, B.R.6
Lichtman, A.H.7
-
67
-
-
0032716177
-
Pain modulation by release of the endogenous cannabinoid anandamide
-
Walker JM, Huang SM, Strangman NM, Tsou K, Sanudo-Pena MC: Pain modulation by release of the endogenous cannabinoid anandamide. Proc Natl Acad Sci USA (1999) 96(21):12198-12203.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, Issue.21
, pp. 12198-12203
-
-
Walker, J.M.1
Huang, S.M.2
Strangman, N.M.3
Tsou, K.4
Sanudo-Pena, M.C.5
-
68
-
-
0036682222
-
The endogenous cannabinoid system controls extinction of aversive memories
-
Marsicano G, Wotjak CT, Azad SC, Bisogno T, Rammes G, Cascio MG, Hermann H, Tang J, Hofmann C, Zieglgansberger W, Di Marzo V, Lutz B: The endogenous cannabinoid system controls extinction of aversive memories. Nature (2002) 418(6897):530-534.
-
(2002)
Nature
, vol.418
, Issue.6897
, pp. 530-534
-
-
Marsicano, G.1
Wotjak, C.T.2
Azad, S.C.3
Bisogno, T.4
Rammes, G.5
Cascio, M.G.6
Hermann, H.7
Tang, J.8
Hofmann, C.9
Zieglgansberger, W.10
Di Marzo, V.11
Lutz, B.12
-
69
-
-
12944277105
-
Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide
-
Boger DL, Sato H, Lerner AE, Hedrick MP, Fecik RA, Miyauchi H, Wilkie GD, Austin BJ, Patricelli MP, Cravatt BF: Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide. Proc Natl Acad Sci USA (2000) 97(10):5044-5049.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, Issue.10
, pp. 5044-5049
-
-
Boger, D.L.1
Sato, H.2
Lerner, A.E.3
Hedrick, M.P.4
Fecik, R.A.5
Miyauchi, H.6
Wilkie, G.D.7
Austin, B.J.8
Patricelli, M.P.9
Cravatt, B.F.10
-
70
-
-
4644354869
-
Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity
-
Lichtman A, Leung D, Shelton CC, Saghatelian A, Hardouin C, Boger DL, Cravatt BF: Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: Evidence for an unprecedented combination of potency and selectivity. J Pharmacol Exp Ther (2004) 311(2):441-448.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.311
, Issue.2
, pp. 441-448
-
-
Lichtman, A.1
Leung, D.2
Shelton, C.C.3
Saghatelian, A.4
Hardouin, C.5
Boger, D.L.6
Cravatt, B.F.7
-
71
-
-
0037234363
-
Modulation of anxiety through blockade of anandamide hydrolysis
-
Kathuria S, Gaetani S, Fegley D, Valino F, Duranti A, Tontini A, Mor M, Tarzia G, La Rana G, Calignano A, Giustino A et al: Modulation of anxiety through blockade of anandamide hydrolysis. Nat Med (2003) 9(1):76-81.
-
(2003)
Nat. Med.
, vol.9
, Issue.1
, pp. 76-81
-
-
Kathuria, S.1
Gaetani, S.2
Fegley, D.3
Valino, F.4
Duranti, A.5
Tontini, A.6
Mor, M.7
Tarzia, G.8
La Rana, G.9
Calignano, A.10
Giustino, A.11
-
72
-
-
12444260741
-
Design, synthesis and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors
-
Tarzia G, Duranti A, Tontini A, Piersanti G, Mor M, Rivara S, Plazzi PV, Park C, Kathuria S, Piomelli D: Design, synthesis and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors. J Med Chem (2003) 46(12):2352-2360.
-
(2003)
J. Med. Chem.
, vol.46
, Issue.12
, pp. 2352-2360
-
-
Tarzia, G.1
Duranti, A.2
Tontini, A.3
Piersanti, G.4
Mor, M.5
Rivara, S.6
Plazzi, P.V.7
Park, C.8
Kathuria, S.9
Piomelli, D.10
-
73
-
-
4744354729
-
Cyclohexylcarbamic acid 3′- or 4′-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: Synthesis, quantitative structure-activity relationships and molecular modeling studies
-
Mor M, Rivara S, Lodola A, Plazzi PV, Tarzia G, Duranti A, Tonfini A, Piersanti G, Kathuria S, Piomelli D: Cyclohexylcarbamic acid 3′- or 4′-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: Synthesis, quantitative structure-activity relationships and molecular modeling studies. J Med Chem (2004) 47(9):4998-5008.
-
(2004)
J. Med. Chem.
, vol.47
, Issue.9
, pp. 4998-5008
-
-
Mor, M.1
Rivara, S.2
Lodola, A.3
Plazzi, P.V.4
Tarzia, G.5
Duranti, A.6
Tonfini, A.7
Piersanti, G.8
Kathuria, S.9
Piomelli, D.10
-
74
-
-
0041423730
-
Interneuron diversity series: Rhythm and mood in perisomatic inhibition
-
Freund T: Interneuron diversity series: Rhythm and mood in perisomatic inhibition. Trends Neurosci (2003) 26(a):489-495.
-
(2003)
Trends Neurosci.
, vol.26 a
, pp. 489-495
-
-
Freund, T.1
|