Expression of APP in transgenic mice: A comparison of neuron-specific promoters

Neurobiology of Aging

Volumn 17, Issue 2, 1996, Pages 183-190

  Andrä, Kerstin ^a   Abramowski, Dorothee ^a   Duke, Mairead ^a   Probst, Alphonse ^c   Wiederhold, Karl Heinz ^a   Bürki, Kurt ^a   Goedert, Michel ^b   Sommer, Bernd ^a   Staufenbiel, Matthias ^a  

^a Preclinical Research   (Switzerland)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c NONE

Author keywords

Alzheimer's disease; Promoter comparison; Transgenic mice; Amyloid precursor protein

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE;

EID: 0029951776     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-4580(95)02066-7     Document Type: Article

References (51)

1. Abramowski, D.; Staufenbiel, M. Identification of the 5-hydroxytryptamine 2C receptor as a 60 kDa N-glycosylated protein in choroid plexus and hippocampus. J. Neurochem. 65:782-790; 1995.
2. Beaudet, L.; Charron, G.; Houle, D.; Tretjakoff, I.; Peterson, A.; Julien, J. P. Intragenic regulatory elements contribute to transcriptional control of the neurofilament light gene. Gene 116:205-214; 1992.
3. Beaudet, L.; Cote, F.; Houle, D.; Julien, J. P. Different posttranslational controls for the human neurofilament light and heavy genes in transgenic mice. Mol. Brain Res. 18:23-31; 1993.
4. Boehm, T.; Greenberg, J. M.; Buluwela, L.; Lavenir, I.: Foster, A.; Rabbitts, T. H. An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs. EMBO J. 9:857-868; 1990.
5. Bowes, M. P.; Masliah, E.; Otero, D. A. C.; Zivin, J. A.; Saitoh, T. Reduction of neuronal damage by a peptide segment of the amyloid/A4 protein precursor in a rabbit spinal cord ischemia model. Exp. Neurol. 129:112-119; 1994.
6. Cai, X.-D.; Golde, T. E.; Younkin, S. G. Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science 259:514-516; 1993.
7. Catoretti, G.; Pilleri, S.; Paravicini, C.; Becker, M.; Poggi, S.; Bifulco, C.; Key, G.; D'Amato, L.; Sabatini, E.; Feudale, E.; Reynolds, F.; Gredes, J.; Rile, F. Antigen unmasking on formalin-fixed paraffin-embedded tissue sections. J. Pathol. 171:83-98; 1993.
8. Chartier-Harlin, M.-C.: Crawford, F.; Houlden, H.; Warren, A.; Hughes, D.; Fidani, L.; Goate, A.; Rossor, M.; Roques, P.; Hardy, J.; Mullan, M. Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene. Nature 353:844-846; 1991.
9. Chomczynski, P.; Sacchi, N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159; 1987.
10. Citron, M.; Oltersdorf, T.; Haass, C.; McConlogue, L.; Hung, A. Y.; Seubert, P.; Vigo-Pelfrey, C.; Lieberburg, I.; Selkoe, D. J. Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production. Nature 360:672-674; 1992.
11. Gallyas F. Silver staining of Alzheimer's neurofibrillary changes by means of physical development. Acta Morphol. Acad. Sci. Hung. 19: 1-8; 1971.
12. Games, D.; Adams, D.; Alessandrini, R.; Barbour, R.; Berthelette, P.; Blackwell, C.; Carr, T.; Clemens, J.; Donaldson, T.; Gillespie, F.; Guido, T.; Hagopian, S.; Johnson-Wood, K.; Khan, K.; Lee, M.; Leibowitz, P.; Lieberburg, I.; Little, S.; Masliah, E.; McConlogue, L.; Montoya-Zavala, M.; Mucke, L.; Paganini, L.; Penniman, E.; Power, M.; Schenk, D.; Seubert, P.; Snyder, B.; Soriano, F.; Tan, H.; Vitale, J.; Wadsworth, S.; Wolozin, B.; Zhao, J. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373:523-528; 1995.
13. Goate, A.; Chartier-Harlin, M.-C.; Mullan, M.; Brown, J.; Crawford, F.; Fidani, L.; Giuffra, L.; Haynes, A.; Irving, N.; James, L.; Mant, R.; Newton, P., Rooke, K.; Roques, P.; Talbot, C.; Periak-Vance, M.; Roses, A.; Williamson, R.; Rossor, M.; Qwen, M.; Hardy, J. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349:704-706; 1991.
14. Gordon, W. J.; Ghesa, G. P.; Nishimura, H.; Rettig, W. J.; Maccari, J. E.; Endo, T.; Seravalli, E.; Seki, T.; Silver, J. Regulation of Thy-1 gene expression in transgenic mice. Cell 50:445-452; 1987.
15. Higgins, L. S.; Rodems, J. M.; Catalano, R.; Quon, D.; Cordell, B. Early Alzheimer's disease-like histopathology increases in frequency with age in mice transgenic for β-APP751. Proc. Natl. Acad. Sci. USA 92:4402-4406; 1994.
16. Hogan, B.; Constantini, F.; Lacy, E.; Manipulating the mouse embryo. A laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press: 1986.
17. Jin, L. W.; Ninomiya, H.; Roch, J. M.; Schubert, D.; Masliah, E.; Otero, D. A.; Saitoh, T. Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension. J. Neurosci. 14:5461-5470; 1994.
18. Julien, J. P.; Tretjakoff, I.; Beaudet, L.; Peterson, A. Expression and assembly of a human neurofilament protein in transgenic mice provide a novel neuronal marking system. Genes Dev. 1:1085-1095; 1987.
19. Kitaguchi, N.; Takahashi, Y.; Tokushima, Y.; Shiojiri, S.; Ito, H. Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 331:530-532; 1988.
20. Kim, K. S.; Wen, G. Y.; Bancher, C.; Chen, C. M. J.; Sapienza, V. J.; Hong H.: Wisniewski, H. M. Detection and quantitation of amyloid β-peptide with 2 monoclonal antibodies. Neurosci. Res. Commun. 7:113-122; 1990.
21. Kozak, M. At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. J. Mol. Biol. 196:947-950; 1987.
22. Lorenzo, A.; Yankner, B. A.; Beta amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc. Natl. Acad. Sci. USA 91:12243-12247; 1994.
23. Ma, J.; Yee, A.; Brewer, B. H.; Das, S.; Potter, H. Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 372:92-94; 1994.
24. Mattson, M. P.; Cheng, B.; Culwell, A. R.; Esch, F. S.; Lieberburg, I.; Rydel, R. E. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein. Neuron 10:243-254; 1993.
25. Milward, E. A.; Papadopoulos, R.; Fuller, S. J.; Moir, R. D.; Small, D.; Beyreuther, K.; Masters, C. L. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron 9:129-137; 1992.
26. Mucke, L.; Masliah, E.; Johnson, W. B.; Ruppe, M. D.; Alford, M.; Rockenstein, E. M.; Forss-Petter, S.; Pietropaolo, M.; Mallory, M.; Abraham, C. R. Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice. Brain Res. 666:151-167; 1994.
27. Mullan, M.; Crawford, F.; Axelman, K.; Houlden, H.; Lilius, L.; Winblad, B.; Lannfelt, L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid. Nat. Genet. 1:345-347: 1992.
28. Murrell, J.; Farlow, M.; Ghetti, B.; Benson, M. D. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science 254:97-99; 1991.
29. Ninomiya, H.; Roch, J. M.; Jin, C. W.; Saitoh, T. Secreted form of amyloid betaA4 protein precursor (APP) binds to two distinct APP binding sites on rat B103 neuron like cells through two different domains, but only one site is involved in neuritotropic activity. J. Neurochem. 63:495-500: 1994.
30. Palacios, G.; Palacios, J. M.; Mengod, G.; Frey, P. β-amyloid precursor protein localization in the Golgi apparatus in neurons and oligodendrocytes. An immunocytochemical, structural and ultrastructural study in normal and axotomized neurons. Mol. Brain Res. 15:195-206; 1992.
31. Palmert, M. R.; Podlisny, M. B.; Witker, D. S.; Oltersdorf, T.; Younkin, L. H.; Selkoe, D. J.; Younkin, S. G. The β-amyloid protein precursor of Alzheimer's disease has soluble derivatives found in human brain and cerebrospinal fluid. Proc. Natl. Acad. Sci. USA 86: 6338-6342; 1989.
32. Ponte, P.; Gonzalez-deWhitt, P.; Schilling, J.; Miller, J.; Hsu, D.; Greenberg, B.; Davis, K.; Wallace, W.; Lieberburg, I.; Fuller, F.; Cordell, B. A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature 331:525-527; 1988.
33. Quon, D.; Wang, Y.; Catalano, R.; Scardina, J. M.; Murakami, K.; Cordell, B. Formation of β-amyloid protein deposits in brains of transgenic mice. Nature 352:239-241; 1991.
34. Roch, J. M.; Masliah, E.; Roch-Levecq, A. C.; Sundsmo, M. P.; Otero, D. A.; Veinbergs, I.; Saitoh, T. Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor. Proc. Natl. Acad. Sci. USA 91: 7450-7454; 1994.
35. Sakimura, K.; Kushiya, E.; Takahashi, Y.; Suzuki, Y. The structure and expression of the neuron-specific enolase gene. Gene 60:103-113; 1987.
36. Sambrook, J.; Fritsch, E. F.; Maniatis, T. Molecular cloning: A laboratory manual. Cold Spring Harbor. NY: Cold Spring Harbor Laboratory Press: 1989.
37. de Sauvage, F.; Kruys, V.; Marinx, O.; Huez, G.; Octave, J. N. Alternative polyadenylation of the amyloid protein precursor mRNA regulates translation. EMBO J. 11:3099-3103; 1992.
38. Schwarzman, A. L.; Gregori, L.; Vitek, M. P.; Lyubski, S.; Strittmatter, W. J.; Enghilde, J. J.; Bhasin, R.; Silverman, J.; Weisgraber, K. H.; Coyle, P. K.; Zagorsky, M. G.; Talalbus, J.; Eisenberg, M.; Saunders, A. M.; Roses, A. D.; Goldgaber, D. Transthyretin sequesters amyloid β protein and prevents amyloid formation. Proc. Natl. Acad. Sci. USA 91:8368-8372: 1994.
39. Seki, T.; Spurr, N.; Obata, F.; Covert, S.; Goodfellow, P.; Silver, J. The human Thy-1 gene: Structure and chromosomal location. Proc. Natl. Acad. Sci. USA 82:6657-6661; 1985.
40. Sidman, R. L.; Angevine, J. B.; Taher Pierce, E. Atlas of the mouse brain and spinal cord. Cambridge. MA: Harvard University Press; 1971.
41. Small, D. H.; Nurcombe. V.; Reed, G.; Clarris, H.; Moir, R.; Beyreuther, K.; Masters, C. L. A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth. J. Neurosci. 14:2117-2127; 1994.
42. Smith-Swintosky, V. L.; Pettigrew, L. C.; Craddock, S. D.; Culwell, A. R.; Rydel, R. E.; Mattson, M. P. Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury. J. Neurochem. 63:781-784; 1994.
43. Snow, A. D.; Sekiguchi, R.; Nochlin, D.; Fraser, P.; Kimata, K.; Mitzutani, A.; Arai, M.; Schreier, W. A.; Morgan, D. G. An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistance of fibrillar Aβ-amyloid in rat brain. Neuron 12:219-234; 1994.
44. Sola, C.; Mengod, G.; Probst, A.; Palacios, J. M. Differential regional and cellular distribution of beta-amyloid precursor protein messenger RNAs containing and lacking the Kunitz protease inhibitor domain in the brain of human, rat and mouse. Neuroscience 53:267-295; 1993.
45. Staufenbiel, M.; Lazarides, L.; Ankyrin is fatty acid acylated in erythrocytes. Proc. Natl. Acad. Sci. USA 83:318-322; 1986.
46. Suzuki, N.; Cheung, T. T.; Cai, X.-D.; Odaka, A.; Otvos Jr., L.; Eckman, C.; Golde, T. E.; Younkin, S. G. An increased percentage of long amyloid β protein secreted by familial amyloid β protein precursor (βAPP717) mutants. Science 264:1336-1340; 1994.
47. Tooze, J. Molecular biology of tumor viruses. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1980.
48. Wasco, W.; Bupp, K.; Magendantz, M.; Gusella, J. F.; Tanzi, R. E.; Solomon, F. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer's disease-associated amyloid β protein precursor. Proc. Natl. Acad. Sci. USA 89:10758-10762; 1992.
49. Weidemann, A.; König, G.; Bunke, D.; Fischer, P.; Salbaum, J. M.; Masters, C. L.; Beyreuther, K. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57:115-126; 1989.
50. Yamamoto, K.; Miyoshi, T.; Yae, T.; Kawashima, K.; Araki, H.; Hanada, K.; Otero, D. A.; Roch, J. M.; Saitoh, T. The survival of rat cerebral cortical neurons in the presence of trophic APP peptides. J. Neurobiol. 25:585-594; 1994.
51. Zaidi, S. H.; Malter, J. S. Amyloid precursor protein mRNA stability is controlled by a 29-base element in the 3′-untranslated region. J. Biol. Chem. 269:24007-24013; 1994.