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Volumn 30, Issue 2, 2011, Pages 129-146

Macrophages in uveal melanoma and in experimental ocular tumor models: Friends or foes?

Author keywords

Immune privilege; Inflammation; Macrophage; Ocular oncology; Uveal melanoma; Vascular endothelial growth factor

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; CD163 ANTIGEN; CD68 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CYCLOOXYGENASE 2 INHIBITOR; GAMMA INTERFERON; GELATINASE B; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PLACENTAL GROWTH FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; VASCULOTROPIN A;

EID: 79551644530     PISSN: 13509462     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.preteyeres.2010.11.004     Document Type: Review
Times cited : (64)

References (177)
  • 1
    • 11344256945 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in uveal melanoma is independent of 6p21-region copy number
    • Abdel-Rahman M.H., Craig E.L., Davidorf F.H., Eng C. Expression of vascular endothelial growth factor in uveal melanoma is independent of 6p21-region copy number. Clin. Cancer Res. 2005, 11:73-78.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 73-78
    • Abdel-Rahman, M.H.1    Craig, E.L.2    Davidorf, F.H.3    Eng, C.4
  • 2
    • 41149164902 scopus 로고    scopus 로고
    • The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance
    • Allavena P., Sica A., Garlanda C., Mantovani A. The yin-yang of tumor-associated macrophages in neoplastic progression and immune surveillance. Immunol. Rev. 2008, 222:155-161.
    • (2008) Immunol. Rev. , vol.222 , pp. 155-161
    • Allavena, P.1    Sica, A.2    Garlanda, C.3    Mantovani, A.4
  • 3
    • 33748353004 scopus 로고    scopus 로고
    • Macrophages inhibit neovascularisation in a murine model of age-related macular degeneration
    • Apte R.S., Richter J., Herndon J., Ferguson T.A. Macrophages inhibit neovascularisation in a murine model of age-related macular degeneration. PLoS Med. 2006, 3:e310-e320.
    • (2006) PLoS Med. , vol.3
    • Apte, R.S.1    Richter, J.2    Herndon, J.3    Ferguson, T.A.4
  • 4
    • 0030890616 scopus 로고    scopus 로고
    • Aging is associated with reduced deposition of specific extracellular matrix components, an upregulation of angiogenesis, and an altered inflammatory response in a murine incisional wound healing model
    • Ashcroft G.S., Horan M.A., Ferguson M.W.J. Aging is associated with reduced deposition of specific extracellular matrix components, an upregulation of angiogenesis, and an altered inflammatory response in a murine incisional wound healing model. J. Invest. Dermatol. 1997, 108:430-437.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 430-437
    • Ashcroft, G.S.1    Horan, M.A.2    Ferguson, M.W.J.3
  • 5
    • 67349216128 scopus 로고    scopus 로고
    • Effectiveness of treatments for metastatic uveal melanoma
    • Augsburger J.J., Correa Z.M., Shaikh A.H. Effectiveness of treatments for metastatic uveal melanoma. Am. J. Ophthalmol. 2009, 148:119-127.
    • (2009) Am. J. Ophthalmol. , vol.148 , pp. 119-127
    • Augsburger, J.J.1    Correa, Z.M.2    Shaikh, A.H.3
  • 6
    • 0029867554 scopus 로고    scopus 로고
    • Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
    • Barleon B., Sozzani S., Zhou D., Weich H.A., Mantovani A., Marme D. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996, 87:3336-3343.
    • (1996) Blood , vol.87 , pp. 3336-3343
    • Barleon, B.1    Sozzani, S.2    Zhou, D.3    Weich, H.A.4    Mantovani, A.5    Marme, D.6
  • 8
    • 0027407109 scopus 로고
    • Endothelial-leukocyte adhesion molecules
    • Bevilacqua M.P. Endothelial-leukocyte adhesion molecules. Annu. Rev. Immunol. 1993, 11:767-804.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 767-804
    • Bevilacqua, M.P.1
  • 12
    • 34249323028 scopus 로고    scopus 로고
    • MHC Class II-transduced tumor cells originating in the immune-privileged eye prime and boost CD4+ T lymphocytes that cross-react with primary and metastatic uveal melanoma cells
    • Bosch J.J., Thompson J.A., Srivastava M.K., Iheagwara U.K., Murray T.G., Lotem M., Ksander B.R., Ostrand-Rosenberg S. MHC Class II-transduced tumor cells originating in the immune-privileged eye prime and boost CD4+ T lymphocytes that cross-react with primary and metastatic uveal melanoma cells. Cancer Res. 2007, 67:4499-4506.
    • (2007) Cancer Res. , vol.67 , pp. 4499-4506
    • Bosch, J.J.1    Thompson, J.A.2    Srivastava, M.K.3    Iheagwara, U.K.4    Murray, T.G.5    Lotem, M.6    Ksander, B.R.7    Ostrand-Rosenberg, S.8
  • 15
    • 0036221217 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is elevated in ocular fluids of eyes harbouring uveal melanoma: identification of a potential therapeutic window
    • Boyd S.R., Tan D., Bruce C., Gittos A., Neale M.H., Hungerford J.L., Charnock-Jones S., Cree I.A. Vascular endothelial growth factor is elevated in ocular fluids of eyes harbouring uveal melanoma: identification of a potential therapeutic window. Br. J. Ophthalmol. 2002, 86:448-452.
    • (2002) Br. J. Ophthalmol. , vol.86 , pp. 448-452
    • Boyd, S.R.1    Tan, D.2    Bruce, C.3    Gittos, A.4    Neale, M.H.5    Hungerford, J.L.6    Charnock-Jones, S.7    Cree, I.A.8
  • 20
    • 28944437419 scopus 로고    scopus 로고
    • Development of metastatic disease after enrolment in the COMS trials for treatment of choroidal melanoma
    • COMS
    • COMS Development of metastatic disease after enrolment in the COMS trials for treatment of choroidal melanoma. Arch. Ophthalmol. 2005, 123:1639-1643.
    • (2005) Arch. Ophthalmol. , vol.123 , pp. 1639-1643
  • 21
    • 33644862258 scopus 로고    scopus 로고
    • Ocular versus extraocular neovascularisation: mirror images or vague resemblances
    • Campochiaro P.A. Ocular versus extraocular neovascularisation: mirror images or vague resemblances. Invest. Ophthalmol. Vis. Sci. 2006, 47:462-474.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 462-474
    • Campochiaro, P.A.1
  • 23
    • 43649109034 scopus 로고    scopus 로고
    • Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis
    • Chang S.-H., Worley L.A., Onken M.O., Harbour J.W. Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis. Melanoma Res. 2008, 18:191-200.
    • (2008) Melanoma Res. , vol.18 , pp. 191-200
    • Chang, S.-H.1    Worley, L.A.2    Onken, M.O.3    Harbour, J.W.4
  • 24
    • 35449004025 scopus 로고    scopus 로고
    • Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion
    • Chen P.W., Mellon J.K., Mayhew E., Wang S., He Y.G., Hogan N., Niederkorn J.Y. Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion. Exp. Eye Res. 2007, 85:617-625.
    • (2007) Exp. Eye Res. , vol.85 , pp. 617-625
    • Chen, P.W.1    Mellon, J.K.2    Mayhew, E.3    Wang, S.4    He, Y.G.5    Hogan, N.6    Niederkorn, J.Y.7
  • 25
    • 0035004299 scopus 로고    scopus 로고
    • Lack of lamphangiogenesis despite coexpression of VEGF-C and its receptor Flt-4 in uveal melanoma
    • Clarijs R., Schalkwijk L., Ruiter D.L., De Waal R.M. Lack of lamphangiogenesis despite coexpression of VEGF-C and its receptor Flt-4 in uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2001, 42:1422-1428.
    • (2001) Invest. Ophthalmol. Vis. Sci. , vol.42 , pp. 1422-1428
    • Clarijs, R.1    Schalkwijk, L.2    Ruiter, D.L.3    De Waal, R.M.4
  • 26
    • 0037406874 scopus 로고    scopus 로고
    • EMAP-II expression is associated with macrophage accumulation in primary uveal melanoma
    • Clarijs R., Schalkwijk L., Ruiter D.J., de Waal R.M.W. EMAP-II expression is associated with macrophage accumulation in primary uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2003, 44:1801-1806.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 1801-1806
    • Clarijs, R.1    Schalkwijk, L.2    Ruiter, D.J.3    de Waal, R.M.W.4
  • 28
    • 53149093203 scopus 로고    scopus 로고
    • Routes of extraocular extension of uveal melanoma: risk factors and influence on survival probability
    • Coupland S.E., Campbell I., Damato B. Routes of extraocular extension of uveal melanoma: risk factors and influence on survival probability. Ophthalmology 2008, 115:1778-1785.
    • (2008) Ophthalmology , vol.115 , pp. 1778-1785
    • Coupland, S.E.1    Campbell, I.2    Damato, B.3
  • 30
    • 54449091663 scopus 로고    scopus 로고
    • Interleukin-10 promotes pathological angiogenesis by regulating macrophage response to hypoxia during development
    • Dace D.S., Khan A.A., Kelly J., Apte R.S. Interleukin-10 promotes pathological angiogenesis by regulating macrophage response to hypoxia during development. PLoS ONE 2008, 3(10):e3381.
    • (2008) PLoS ONE , vol.3 , Issue.10
    • Dace, D.S.1    Khan, A.A.2    Kelly, J.3    Apte, R.S.4
  • 31
    • 38649095597 scopus 로고    scopus 로고
    • CD4+ T cell-dependent tumor rejection in an immune-privileged environment requires macrophages
    • Dace D.S., Chen P.W., Niederkorn J.Y. CD4+ T cell-dependent tumor rejection in an immune-privileged environment requires macrophages. Immunology 2008, 123:367-377.
    • (2008) Immunology , vol.123 , pp. 367-377
    • Dace, D.S.1    Chen, P.W.2    Niederkorn, J.Y.3
  • 32
    • 1842395125 scopus 로고
    • Immunology and immunotherapy of malignant uveal melanomas
    • Appleton/Century/Crofts, New York, G.A. Peyman, D.J. Apple, D.R. Sanders (Eds.)
    • Davidorf F.H., Lang J.R. Immunology and immunotherapy of malignant uveal melanomas. Intraocular Tumors 1977, 119-133. Appleton/Century/Crofts, New York. G.A. Peyman, D.J. Apple, D.R. Sanders (Eds.).
    • (1977) Intraocular Tumors , pp. 119-133
    • Davidorf, F.H.1    Lang, J.R.2
  • 33
  • 35
    • 0025159229 scopus 로고
    • Lymphocytic infiltration in uveal malignant melanoma
    • De la Cruz P.O., Specht C.S., McLean I.W. Lymphocytic infiltration in uveal malignant melanoma. Cancer 1990, 65:112-115.
    • (1990) Cancer , vol.65 , pp. 112-115
    • De la Cruz, P.O.1    Specht, C.S.2    McLean, I.W.3
  • 36
    • 0030782158 scopus 로고    scopus 로고
    • Macrophages induce apoptosis in normal cells in vivo
    • Diez-Roux G., Lang R.A. Macrophages induce apoptosis in normal cells in vivo. Development 1997, 124:3633-3638.
    • (1997) Development , vol.124 , pp. 3633-3638
    • Diez-Roux, G.1    Lang, R.A.2
  • 37
    • 59849104241 scopus 로고    scopus 로고
    • Molecular pathology of age-related macular degeneration
    • Ding X., Patel M., Chan C.-C. Molecular pathology of age-related macular degeneration. Prog. Retin. Eye Res. 2009, 28:1-18.
    • (2009) Prog. Retin. Eye Res. , vol.28 , pp. 1-18
    • Ding, X.1    Patel, M.2    Chan, C.-C.3
  • 38
    • 1642344452 scopus 로고    scopus 로고
    • Activation of tumor-specific CD4+ T lymphocytes by major histocompatibility class II tumor cell vaccines: a novel cell-based immunotherapy
    • Dissanayake S.K., Thompson J.A., Bosch J.A., Clements V.K., Chen P.W., Ksander B.R., Ostrand-Rosenberg S. Activation of tumor-specific CD4+ T lymphocytes by major histocompatibility class II tumor cell vaccines: a novel cell-based immunotherapy. Cancer Res. 2004, 64:1867-1874.
    • (2004) Cancer Res. , vol.64 , pp. 1867-1874
    • Dissanayake, S.K.1    Thompson, J.A.2    Bosch, J.A.3    Clements, V.K.4    Chen, P.W.5    Ksander, B.R.6    Ostrand-Rosenberg, S.7
  • 39
    • 0036705906 scopus 로고    scopus 로고
    • HLA-I-Antigenexpression korreliert mit dem histologischen Zelltyp Uvealer Melanome
    • Dithmar S., Crowder J., Jager M.J., Vigniswaran N., Grossniklau H.E. HLA-I-Antigenexpression korreliert mit dem histologischen Zelltyp Uvealer Melanome. Ophthalmologe 2002, 99:625-628.
    • (2002) Ophthalmologe , vol.99 , pp. 625-628
    • Dithmar, S.1    Crowder, J.2    Jager, M.J.3    Vigniswaran, N.4    Grossniklau, H.E.5
  • 41
    • 77951239640 scopus 로고    scopus 로고
    • Characterizing the involvement of the nuclear factor/kappa B (NFkB) transcription Factor in uveal melanoma
    • Dror R., Lederman M., Umezawa K., Barak V., Pe'er J., Chowers I. Characterizing the involvement of the nuclear factor/kappa B (NFkB) transcription Factor in uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2010, 51:1811-1816.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 1811-1816
    • Dror, R.1    Lederman, M.2    Umezawa, K.3    Barak, V.4    Pe'er, J.5    Chowers, I.6
  • 43
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M., Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2002, 2:161-174.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 44
    • 53749101548 scopus 로고    scopus 로고
    • Triamcinolone acetonide and anecortave acetate do not stimulate uveal melanoma cell growth
    • El Filali M., Homminga I., Maat W., Van der Velden P.A., Jager M.J. Triamcinolone acetonide and anecortave acetate do not stimulate uveal melanoma cell growth. Mol. Vis. 2008, 14:1752-1759.
    • (2008) Mol. Vis. , vol.14 , pp. 1752-1759
    • El Filali, M.1    Homminga, I.2    Maat, W.3    Van der Velden, P.A.4    Jager, M.J.5
  • 46
    • 0034969317 scopus 로고    scopus 로고
    • MMP-9 is predominantly expressed in epithelioid and not spindle cell uveal melanoma
    • El-Shabrawi Y., Ardjomand N., Radner H., Ardjomand N. MMP-9 is predominantly expressed in epithelioid and not spindle cell uveal melanoma. J. Pathol. 2001, 194:201-206.
    • (2001) J. Pathol. , vol.194 , pp. 201-206
    • El-Shabrawi, Y.1    Ardjomand, N.2    Radner, H.3    Ardjomand, N.4
  • 50
    • 49049092624 scopus 로고    scopus 로고
    • In vivo visualization of dendritic cells, macrophages, and microglial cells responding to laser-induced damage in the fundus of the eye
    • Eter N., Engel D.R., Meyer L., Helb H.-M., Roth F., Maurer J., Holz F.G., Kurts C. In vivo visualization of dendritic cells, macrophages, and microglial cells responding to laser-induced damage in the fundus of the eye. Invest. Ophthalmol. Vis. Sci. 2008, 49:3649-3658.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 3649-3658
    • Eter, N.1    Engel, D.R.2    Meyer, L.3    Helb, H.-M.4    Roth, F.5    Maurer, J.6    Holz, F.G.7    Kurts, C.8
  • 54
    • 10244279184 scopus 로고    scopus 로고
    • Mechanisms and functional significance of tumor-induced dendritic cell defects
    • Gabrilovich D. Mechanisms and functional significance of tumor-induced dendritic cell defects. Nat. Rev. Immunol. 2004, 4:941-952.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 941-952
    • Gabrilovich, D.1
  • 55
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich D.I., Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 2009, 9:162-174.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 58
    • 44849098983 scopus 로고    scopus 로고
    • Modulation of the tumor cell phenotype by IFN gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes
    • Hallermalm K., Seki K., De Geer A., Motyka B., Bleackley R.C., Jager M.J., Frohlich C.J., Levitsky V., Levitskaya J. Modulation of the tumor cell phenotype by IFN gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes. J. Immunol. 2008, 180:3766-3774.
    • (2008) J. Immunol. , vol.180 , pp. 3766-3774
    • Hallermalm, K.1    Seki, K.2    De Geer, A.3    Motyka, B.4    Bleackley, R.C.5    Jager, M.J.6    Frohlich, C.J.7    Levitsky, V.8    Levitskaya, J.9
  • 59
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86:353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 60
    • 0031936155 scopus 로고    scopus 로고
    • Biologic determinants of uveal melanoma metastatic phenotype: role of intermediate filaments as predictive markers
    • Hendrix M.J., Seftor E.A., Seftor R.E., Gardner L.M., Boldt H.G., Meyer M., Pe'er J., Folberg R. Biologic determinants of uveal melanoma metastatic phenotype: role of intermediate filaments as predictive markers. Lab. Invest. 1998, 78:153-163.
    • (1998) Lab. Invest. , vol.78 , pp. 153-163
    • Hendrix, M.J.1    Seftor, E.A.2    Seftor, R.E.3    Gardner, L.M.4    Boldt, H.G.5    Meyer, M.6    Pe'er, J.7    Folberg, R.8
  • 61
    • 0038143145 scopus 로고    scopus 로고
    • Vasculogenic mimicry and tumor-cell plasticity: lessons from melanoma
    • Hendrix M.J., Seftor E.A., Hess A.R., Seftor R.E. Vasculogenic mimicry and tumor-cell plasticity: lessons from melanoma. Nat. Rev. Cancer 2003, 3:411-421.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 411-421
    • Hendrix, M.J.1    Seftor, E.A.2    Hess, A.R.3    Seftor, R.E.4
  • 62
    • 0034044418 scopus 로고    scopus 로고
    • Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo
    • Hofmann U.B., Westphal J.R., van Kraats A.A., Ruiter D.J., Van Muijen G.N. Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivo. Int. J. Cancer 2000, 87:12-19.
    • (2000) Int. J. Cancer , vol.87 , pp. 12-19
    • Hofmann, U.B.1    Westphal, J.R.2    van Kraats, A.A.3    Ruiter, D.J.4    Van Muijen, G.N.5
  • 63
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren L., O'Reilly M.S., Folkman J. Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat. Med. 1995, 1:149-153.
    • (1995) Nat. Med. , vol.1 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.S.2    Folkman, J.3
  • 64
    • 65549143169 scopus 로고    scopus 로고
    • Potential role of macrophages in experimental keratomycosis
    • Hu J., Wang Y., Xie L. Potential role of macrophages in experimental keratomycosis. Invest. Ophthalmol. Vis. Sci. 2009, 50:2087-2094.
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 2087-2094
    • Hu, J.1    Wang, Y.2    Xie, L.3
  • 65
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD15+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang B., Pan P.Y., Li Q., Sato A.I., Levy D.E., Bromberg J., Divino C.M., Chen S.H. Gr-1+CD15+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 2006, 66:1123-1131.
    • (2006) Cancer Res. , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.H.8
  • 67
    • 0032719554 scopus 로고    scopus 로고
    • Expression of angiogenic and immunosuppressive factors by uveal melanoma cell lines
    • IJland S.A., Jager M.J., Heijdra B.M., Westphal J.R., Peek R. Expression of angiogenic and immunosuppressive factors by uveal melanoma cell lines. Melanoma Res. 1999, 9:445-450.
    • (1999) Melanoma Res. , vol.9 , pp. 445-450
    • Ijland, S.A.1    Jager, M.J.2    Heijdra, B.M.3    Westphal, J.R.4    Peek, R.5
  • 68
    • 34447534336 scopus 로고    scopus 로고
    • Expression of collagenase-1 (MMP-1) promotes melanoma growth through the generation of active transforming growth factor-beta
    • Iida J., McCarthy J.B. Expression of collagenase-1 (MMP-1) promotes melanoma growth through the generation of active transforming growth factor-beta. Melanoma Res. 2007, 17:205-213.
    • (2007) Melanoma Res. , vol.17 , pp. 205-213
    • Iida, J.1    McCarthy, J.B.2
  • 70
    • 38549129761 scopus 로고    scopus 로고
    • Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation
    • Itaya M., Sakurai E., Nozaki M., Yamada K., Yamasaki S., Asai K., Ogura Y. Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation. Invest. Ophthalmol. Vis. Sci. 2007, 48:5677-5683.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 5677-5683
    • Itaya, M.1    Sakurai, E.2    Nozaki, M.3    Yamada, K.4    Yamasaki, S.5    Asai, K.6    Ogura, Y.7
  • 71
    • 33749338443 scopus 로고    scopus 로고
    • Angiogenesis in uveal melanoma
    • Jager M.J. Angiogenesis in uveal melanoma. Ophthalmic Res. 2006, 38:248-250.
    • (2006) Ophthalmic Res. , vol.38 , pp. 248-250
    • Jager, M.J.1
  • 72
    • 36048938341 scopus 로고    scopus 로고
    • Macrophages feel their age in macular degeneration
    • Jager M.J., Klaver C.C.W. Macrophages feel their age in macular degeneration. J. Clin. Invest. 2007, 117:3182-3184.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3182-3184
    • Jager, M.J.1    Klaver, C.C.W.2
  • 73
    • 0022655176 scopus 로고
    • Correspondence of the monocyte antigen HMA-1 to the non-HLA antigen 9a
    • Jager M.J., Claas F.H.J., Witvliet M., van Rood J.J. Correspondence of the monocyte antigen HMA-1 to the non-HLA antigen 9a. Immunogenetics 1986, 23:71-77.
    • (1986) Immunogenetics , vol.23 , pp. 71-77
    • Jager, M.J.1    Claas, F.H.J.2    Witvliet, M.3    van Rood, J.J.4
  • 75
    • 0036597825 scopus 로고    scopus 로고
    • HLA expression in uveal melanoma: there is no rule without some exception
    • Jager M.J., Hurks H.M., Levitskaya J., Kiessling R. HLA expression in uveal melanoma: there is no rule without some exception. Hum. Immunol. 2002, 63:444-451.
    • (2002) Hum. Immunol. , vol.63 , pp. 444-451
    • Jager, M.J.1    Hurks, H.M.2    Levitskaya, J.3    Kiessling, R.4
  • 77
    • 36048953291 scopus 로고    scopus 로고
    • Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice
    • Kelly J., Khan A.A., Yin J., Ferguson Th.A., Apte R.S. Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice. J. Clin. Invest. 2007, 117:3421-3426.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3421-3426
    • Kelly, J.1    Khan, A.A.2    Yin, J.3    Ferguson, T.4    Apte, R.S.5
  • 78
    • 56549105942 scopus 로고    scopus 로고
    • Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations
    • Kerr E.C., Raveney B.J., Copland D.A., Dick A.D., Nicholson L.B. Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations. J. Autoimmun. 2008, 31:354-361.
    • (2008) J. Autoimmun. , vol.31 , pp. 354-361
    • Kerr, E.C.1    Raveney, B.J.2    Copland, D.A.3    Dick, A.D.4    Nicholson, L.B.5
  • 80
    • 0023177782 scopus 로고
    • Destructive and non-destructive patterns of immune rejection of syngeneic intraocular tumors
    • Knisely T.L., Luckenbach M.W., Fischer B.J., Niederkorn J.Y. Destructive and non-destructive patterns of immune rejection of syngeneic intraocular tumors. J. Immunol. 1987, 138:4515-4523.
    • (1987) J. Immunol. , vol.138 , pp. 4515-4523
    • Knisely, T.L.1    Luckenbach, M.W.2    Fischer, B.J.3    Niederkorn, J.Y.4
  • 82
    • 0033104736 scopus 로고    scopus 로고
    • Macrophage control of Herpes Simplex virus type 1 replication in the peripheral nervous system
    • Kodukula P., Liu T., van Rooijen N., Jager M.J., Hendricks R.L. Macrophage control of Herpes Simplex virus type 1 replication in the peripheral nervous system. J. Immunol. 1999, 162:2895-2905.
    • (1999) J. Immunol. , vol.162 , pp. 2895-2905
    • Kodukula, P.1    Liu, T.2    van Rooijen, N.3    Jager, M.J.4    Hendricks, R.L.5
  • 83
    • 0142200859 scopus 로고    scopus 로고
    • Very long-term prognosis of patients with malignant uveal melanoma
    • Kujala E., Mäkitie T., Kivelä T. Very long-term prognosis of patients with malignant uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2003, 44:4651-4659.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 4651-4659
    • Kujala, E.1    Mäkitie, T.2    Kivelä, T.3
  • 84
    • 0042591427 scopus 로고    scopus 로고
    • All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination
    • Kusmartsev S., Cheng F., Yu B., Nefedova Y., Sotomayor E., Lush R., Gabrilovich D. All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination. Cancer Res. 2003, 63:4441-4449.
    • (2003) Cancer Res. , vol.63 , pp. 4441-4449
    • Kusmartsev, S.1    Cheng, F.2    Yu, B.3    Nefedova, Y.4    Sotomayor, E.5    Lush, R.6    Gabrilovich, D.7
  • 85
    • 0030296155 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) in retinoblastoma but not in posterior uveal melanoma
    • Kvanta A., Steen B., Seregard S. Expression of vascular endothelial growth factor (VEGF) in retinoblastoma but not in posterior uveal melanoma. Exp. Eye Res. 1996, 63:511-518.
    • (1996) Exp. Eye Res. , vol.63 , pp. 511-518
    • Kvanta, A.1    Steen, B.2    Seregard, S.3
  • 86
    • 44649108198 scopus 로고    scopus 로고
    • Expression and distribution of MMP's and TIMP's in human uveal melanoma
    • Lai K., Conway R.M., Crouch R., Jager M.J., Madigan M.C. Expression and distribution of MMP's and TIMP's in human uveal melanoma. Exp. Eye Res. 2008, 86:936-941.
    • (2008) Exp. Eye Res. , vol.86 , pp. 936-941
    • Lai, K.1    Conway, R.M.2    Crouch, R.3    Jager, M.J.4    Madigan, M.C.5
  • 88
    • 0027225992 scopus 로고
    • Macrophages are required for cell death and tissue remodelling in the developing mouse eye
    • Lang R.A., Bishop M.J. Macrophages are required for cell death and tissue remodelling in the developing mouse eye. Cell 1993, 74:453-462.
    • (1993) Cell , vol.74 , pp. 453-462
    • Lang, R.A.1    Bishop, M.J.2
  • 89
    • 7244238190 scopus 로고    scopus 로고
    • CD163: a specific marker of macrophages in paraffin-embedded tissue samples
    • Lau S.K., Chu P.G., Weiss L.M. CD163: a specific marker of macrophages in paraffin-embedded tissue samples. Am. J. Clin. Pathol. 2004, 122:794-801.
    • (2004) Am. J. Clin. Pathol. , vol.122 , pp. 794-801
    • Lau, S.K.1    Chu, P.G.2    Weiss, L.M.3
  • 90
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek R.D., Lewis C.E., Whitehouse R., Greenall M., Clarke J., Harris A.L. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res. 1996, 56:4625-4629.
    • (1996) Cancer Res. , vol.56 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 91
    • 40649091877 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors on uveal melanoma cells and their metastases
    • Li H., Alizadeh H., Niederkorn J.Y. Differential expression of chemokine receptors on uveal melanoma cells and their metastases. Invest. Ophthalmol. Vis. Sci. 2008, 49:636-643.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 636-643
    • Li, H.1    Alizadeh, H.2    Niederkorn, J.Y.3
  • 92
    • 73349084970 scopus 로고    scopus 로고
    • Inhibition of chemokine receptor expression on uveal melanomas by CXCR4 siRNA and its effect on uveal melanoma liver metastases
    • Li H., Yang W., Chen P.W., Alizadeh H., Niederkorn J.Y. Inhibition of chemokine receptor expression on uveal melanomas by CXCR4 siRNA and its effect on uveal melanoma liver metastases. Invest. Ophthalmol. Vis. Sci. 2009, 50:5522-5528.
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 5522-5528
    • Li, H.1    Yang, W.2    Chen, P.W.3    Alizadeh, H.4    Niederkorn, J.Y.5
  • 94
    • 65549133424 scopus 로고    scopus 로고
    • A phase 1 study of granulocyte macrophage colony-stimulating factor (Sargramostim) and escalating doses of thalidomide in patients with high-risk malignant melanoma
    • Lutzky J., Weber R., Nunez Y., Gillett M., Spitler L. A phase 1 study of granulocyte macrophage colony-stimulating factor (Sargramostim) and escalating doses of thalidomide in patients with high-risk malignant melanoma. J. Immunother. 2009, 32:79-85.
    • (2009) J. Immunother. , vol.32 , pp. 79-85
    • Lutzky, J.1    Weber, R.2    Nunez, Y.3    Gillett, M.4    Spitler, L.5
  • 101
    • 0344631585 scopus 로고    scopus 로고
    • Microvascular density in predicting survival of patients with choroidal and ciliary body melanoma
    • Mäkitie T., Summanen P., Tarkkanen A., Kivelä T. Microvascular density in predicting survival of patients with choroidal and ciliary body melanoma. Invest. Ophthalmol. Vis. Sci. 1999, 40:2471-2480.
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40 , pp. 2471-2480
    • Mäkitie, T.1    Summanen, P.2    Tarkkanen, A.3    Kivelä, T.4
  • 102
    • 0034994770 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages (CD68(+) cells) and prognosis in malignant uveal melanoma
    • Mäkitie T., Summanen P., Tarkkanen A., Kivelä T. Tumor-infiltrating macrophages (CD68(+) cells) and prognosis in malignant uveal melanoma. Invest. Ophthalmol. Vis. Sci. 2001, 42:1414-1421.
    • (2001) Invest. Ophthalmol. Vis. Sci. , vol.42 , pp. 1414-1421
    • Mäkitie, T.1    Summanen, P.2    Tarkkanen, A.3    Kivelä, T.4
  • 103
    • 0034798394 scopus 로고    scopus 로고
    • Ezrin as a prognostic indicator and its relationship to tumor characteristics in uveal malignant melanoma
    • Mäkitie T., Carpen O., Vaheri A., Kivelä T. Ezrin as a prognostic indicator and its relationship to tumor characteristics in uveal malignant melanoma. Invest. Ophthalmol. Vis. Sci. 2001, 42:2442-2449.
    • (2001) Invest. Ophthalmol. Vis. Sci. , vol.42 , pp. 2442-2449
    • Mäkitie, T.1    Carpen, O.2    Vaheri, A.3    Kivelä, T.4
  • 104
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A., Sozzani S., Locati M., Allavena P., Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 2002, 23:549-555.
    • (2002) Trends Immunol. , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 106
    • 41149119143 scopus 로고    scopus 로고
    • Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells
    • Marigo I., Dolcetti L., Serafini P., Zonovello P., Bronte V. Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells. Immunol. Rev. 2008, 222:162-179.
    • (2008) Immunol. Rev. , vol.222 , pp. 162-179
    • Marigo, I.1    Dolcetti, L.2    Serafini, P.3    Zonovello, P.4    Bronte, V.5
  • 108
    • 0038560947 scopus 로고    scopus 로고
    • Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro- and anti-inflammatory cytokines in BALB/c mice
    • McClellan S.A., Huang X., Barrett R.P., van Rooijen N., Hazlett L.D. Macrophages restrict Pseudomonas aeruginosa growth, regulate polymorphonuclear neutrophil influx, and balance pro- and anti-inflammatory cytokines in BALB/c mice. J. Immunol. 2003, 170:5219-5227.
    • (2003) J. Immunol. , vol.170 , pp. 5219-5227
    • McClellan, S.A.1    Huang, X.2    Barrett, R.P.3    van Rooijen, N.4    Hazlett, L.D.5
  • 109
    • 33746214824 scopus 로고    scopus 로고
    • Accumulation of immunosuppressive CD11b+ myeloid cells correlates with the failure to prevent tumor growth in the anterior chamber of the eye
    • McKenna K.C., Kapp J.A. Accumulation of immunosuppressive CD11b+ myeloid cells correlates with the failure to prevent tumor growth in the anterior chamber of the eye. J. Immunol. 2006, 177:1599-1608.
    • (2006) J. Immunol. , vol.177 , pp. 1599-1608
    • McKenna, K.C.1    Kapp, J.A.2
  • 111
    • 0020049093 scopus 로고
    • Uveal melanoma: location, size, cell type, and enucleation as risk factors in metastasis
    • McLean I.W., Foster W.D., Zimmerman L.E. Uveal melanoma: location, size, cell type, and enucleation as risk factors in metastasis. Hum. Pathol. 1982, 13:123-132.
    • (1982) Hum. Pathol. , vol.13 , pp. 123-132
    • McLean, I.W.1    Foster, W.D.2    Zimmerman, L.E.3
  • 112
    • 0032955311 scopus 로고    scopus 로고
    • Dendritic cells and macrophages in the uveal tract of the normal mouse eye
    • McMenamin P.G. Dendritic cells and macrophages in the uveal tract of the normal mouse eye. Br. J. Ophthalmol. 1999, 83:598-604.
    • (1999) Br. J. Ophthalmol. , vol.83 , pp. 598-604
    • McMenamin, P.G.1
  • 114
    • 0033838925 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by Intercellular Adhesion Molecule-1 (ICAM-1)
    • Miyamoto K., Khosrof S., Bursell S.-E., Moromizato Y., Aiello L.P., Ogura Y., Adamis A.P. Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by Intercellular Adhesion Molecule-1 (ICAM-1). Am. J. Pathol. 2000, 156:1733-1739.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1733-1739
    • Miyamoto, K.1    Khosrof, S.2    Bursell, S.-E.3    Moromizato, Y.4    Aiello, L.P.5    Ogura, Y.6    Adamis, A.P.7
  • 115
    • 0036227431 scopus 로고    scopus 로고
    • Role of monocytes and macrophages in adult angiogenesis: a light at the tunnel's end
    • Moldovan N.I. Role of monocytes and macrophages in adult angiogenesis: a light at the tunnel's end. J. Hematother. Stem Cell Res. 2002, 11:179-194.
    • (2002) J. Hematother. Stem Cell Res. , vol.11 , pp. 179-194
    • Moldovan, N.I.1
  • 116
    • 0030293855 scopus 로고    scopus 로고
    • Prognostic parameters in uveal melanoma: a review
    • Mooy C.M., De Jong P.T. Prognostic parameters in uveal melanoma: a review. Surv. Ophthalmol. 1996, 41:215-228.
    • (1996) Surv. Ophthalmol. , vol.41 , pp. 215-228
    • Mooy, C.M.1    De Jong, P.T.2
  • 118
    • 3242808841 scopus 로고    scopus 로고
    • A critical appraisal of the prognostic and predictive factors for uveal malignant melanoma
    • Mudhar H.S., Parsons M.A., Sisley K., Rundle P., Singh A., Rennie I.G. A critical appraisal of the prognostic and predictive factors for uveal malignant melanoma. Histopathology 2004, 45:1-12.
    • (2004) Histopathology , vol.45 , pp. 1-12
    • Mudhar, H.S.1    Parsons, M.A.2    Sisley, K.3    Rundle, P.4    Singh, A.5    Rennie, I.G.6
  • 120
    • 17744387919 scopus 로고    scopus 로고
    • Expression of CD163 (haemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted tot the monocyte/macrophage lineage
    • Nguyen T.T., Schwartz E.J., West R.B., Warnke R.A., Arber D.A., Natkunam Y. Expression of CD163 (haemoglobin scavenger receptor) in normal tissues, lymphomas, carcinomas, and sarcomas is largely restricted tot the monocyte/macrophage lineage. Am. J. Surg. Pathol. 2005, 29:617-624.
    • (2005) Am. J. Surg. Pathol. , vol.29 , pp. 617-624
    • Nguyen, T.T.1    Schwartz, E.J.2    West, R.B.3    Warnke, R.A.4    Arber, D.A.5    Natkunam, Y.6
  • 121
    • 67651183589 scopus 로고    scopus 로고
    • Immune escape mechanisms of intraocular tumors
    • Niederkorn J.Y. Immune escape mechanisms of intraocular tumors. Prog. Retin. Eye Res. 2009, 28:329-347.
    • (2009) Prog. Retin. Eye Res. , vol.28 , pp. 329-347
    • Niederkorn, J.Y.1
  • 122
    • 5644251671 scopus 로고    scopus 로고
    • Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death
    • Onken M.D., Worley L.A., Ehlers J.P., Harbour J.W. Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Res. 2004, 64:7205-7209.
    • (2004) Cancer Res. , vol.64 , pp. 7205-7209
    • Onken, M.D.1    Worley, L.A.2    Ehlers, J.P.3    Harbour, J.W.4
  • 123
    • 26844520916 scopus 로고    scopus 로고
    • Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas
    • Onken M.D., Lin A.Y., Worley L.A., Folberg R., Harbour J.W. Association between microarray gene expression signature and extravascular matrix patterns in primary uveal melanomas. Am. J. Ophthalmol. 2005, 140:748-749.
    • (2005) Am. J. Ophthalmol. , vol.140 , pp. 748-749
    • Onken, M.D.1    Lin, A.Y.2    Worley, L.A.3    Folberg, R.4    Harbour, J.W.5
  • 124
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • Ostrand-Rosenberg S., Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J. Immunol. 2009, 182:4499-4506.
    • (2009) J. Immunol. , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 125
    • 33645738383 scopus 로고    scopus 로고
    • Towards third generation matrix metalloproteinase inhibitors for cancer therapy
    • Overall C.M., Kleifeld O. Towards third generation matrix metalloproteinase inhibitors for cancer therapy. Br. J. Cancer 2006, 94:941-946.
    • (2006) Br. J. Cancer , vol.94 , pp. 941-946
    • Overall, C.M.1    Kleifeld, O.2
  • 126
    • 0029018364 scopus 로고
    • Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases
    • Pe'er J., Shweiki D., Itin A., Hemo I., Gnessin H., Keshet E. Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases. Lab. Invest. 1995, 72:638-645.
    • (1995) Lab. Invest. , vol.72 , pp. 638-645
    • Pe'er, J.1    Shweiki, D.2    Itin, A.3    Hemo, I.4    Gnessin, H.5    Keshet, E.6
  • 128
    • 34447522630 scopus 로고    scopus 로고
    • Dendritic cell-mediated immunosuppression in malignant melanoma
    • Polak M.E., Borthwick N.J., Jager M.J., Cree I.A. Dendritic cell-mediated immunosuppression in malignant melanoma. Cancer Ther. 2003, 1:393-405.
    • (2003) Cancer Ther. , vol.1 , pp. 393-405
    • Polak, M.E.1    Borthwick, N.J.2    Jager, M.J.3    Cree, I.A.4
  • 130
    • 63149088164 scopus 로고    scopus 로고
    • Trophic macrophages in development and disease
    • Pollard J.W. Trophic macrophages in development and disease. Nat. Rev. Immunol. 2009, 9:259-270.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 259-270
    • Pollard, J.W.1
  • 131
    • 0018292115 scopus 로고
    • Vessels of intraocular malignant melanomas
    • Radnot M., Antal M. Vessels of intraocular malignant melanomas. Am. J. Ophthalmol. 1979, 88:472-478.
    • (1979) Am. J. Ophthalmol. , vol.88 , pp. 472-478
    • Radnot, M.1    Antal, M.2
  • 132
    • 37349082926 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their inhibitors in vascular remodelling and vascular disease
    • Raffetto J.D., Khalil R.A. Matrix metalloproteinases and their inhibitors in vascular remodelling and vascular disease. Biochem. Pharmacol. 2007, 75:346-359.
    • (2007) Biochem. Pharmacol. , vol.75 , pp. 346-359
    • Raffetto, J.D.1    Khalil, R.A.2
  • 133
    • 0034661868 scopus 로고    scopus 로고
    • Human uveal melanoma cells produce macrophage migration-inhibitory factor to prevent lysis by NK cells
    • Repp A.C., Mayhew E.S., Apte S., Niederkorn J.Y. Human uveal melanoma cells produce macrophage migration-inhibitory factor to prevent lysis by NK cells. J. Immunol. 2000, 165:710-715.
    • (2000) J. Immunol. , vol.165 , pp. 710-715
    • Repp, A.C.1    Mayhew, E.S.2    Apte, S.3    Niederkorn, J.Y.4
  • 134
    • 35248814227 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor-A, matrix metalloproteinase-9, and extravascular matrix patterns and their correlations with clinicopathologic parameters in posterior uveal melanomas
    • Sahin A., Kiratli H., Soylemezoglu F., Tezel G.G., Bilgic S., Saracbasi O. Expression of vascular endothelial growth factor-A, matrix metalloproteinase-9, and extravascular matrix patterns and their correlations with clinicopathologic parameters in posterior uveal melanomas. Jpn. J. Ophthalmol. 2007, 51:325-331.
    • (2007) Jpn. J. Ophthalmol. , vol.51 , pp. 325-331
    • Sahin, A.1    Kiratli, H.2    Soylemezoglu, F.3    Tezel, G.G.4    Bilgic, S.5    Saracbasi, O.6
  • 135
    • 0035889886 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide
    • Saio M., Radoja S., Marino M., Frey A.B. Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide. J. Immunol. 2001, 167:5583-5593.
    • (2001) J. Immunol. , vol.167 , pp. 5583-5593
    • Saio, M.1    Radoja, S.2    Marino, M.3    Frey, A.B.4
  • 138
  • 140
    • 0021053975 scopus 로고
    • A prognostic factor study of disease-free interval and survival following enucleation of uveal melanoma
    • Seddon J.M., Albert D.M., Lavin P.T., Robinson N. A prognostic factor study of disease-free interval and survival following enucleation of uveal melanoma. Arch. Ophthalmol. 1983, 101:1894-1899.
    • (1983) Arch. Ophthalmol. , vol.101 , pp. 1894-1899
    • Seddon, J.M.1    Albert, D.M.2    Lavin, P.T.3    Robinson, N.4
  • 141
    • 0035417897 scopus 로고    scopus 로고
    • Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma
    • Seftor R.E., Seftor E.A., Koshikawa N., Meltzer P.S., Gardner L.M., Bilban M., Stetler-Stevenson W.G., Quaranta V., Hendrix M.J. Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma. Cancer Res. 2001, 61:6322-6327.
    • (2001) Cancer Res. , vol.61 , pp. 6322-6327
    • Seftor, R.E.1    Seftor, E.A.2    Koshikawa, N.3    Meltzer, P.S.4    Gardner, L.M.5    Bilban, M.6    Stetler-Stevenson, W.G.7    Quaranta, V.8    Hendrix, M.J.9
  • 142
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: pathophysiology and therapeutics
    • Semenza G.L. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 2002, 8(4 Suppl.):S62-S67.
    • (2002) Trends Mol. Med. , vol.8 , Issue.4 SUPPL.
    • Semenza, G.L.1
  • 143
    • 0033921038 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in uveal melanoma and its correlation with metastasis
    • Sheidow T.G., Hooper P.L., Crukley C., Young J., Heathcote J.G. Expression of vascular endothelial growth factor in uveal melanoma and its correlation with metastasis. Br. J. Ophthalmol. 2000, 84:750-756.
    • (2000) Br. J. Ophthalmol. , vol.84 , pp. 750-756
    • Sheidow, T.G.1    Hooper, P.L.2    Crukley, C.3    Young, J.4    Heathcote, J.G.5
  • 144
    • 47749155653 scopus 로고    scopus 로고
    • Cancer-related inflammation: the macrophage connection
    • Sica A., Allavena P., Mantovani A. Cancer-related inflammation: the macrophage connection. Cancer Lett. 2008, 264:204-215.
    • (2008) Cancer Lett. , vol.264 , pp. 204-215
    • Sica, A.1    Allavena, P.2    Mantovani, A.3
  • 147
    • 0037542842 scopus 로고    scopus 로고
    • Incidence of uveal melanoma in the United States: 1973-1997
    • Singh A.D., Topham A. Incidence of uveal melanoma in the United States: 1973-1997. Ophthalmology 2003, 110:956-961.
    • (2003) Ophthalmology , vol.110 , pp. 956-961
    • Singh, A.D.1    Topham, A.2
  • 148
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • Sinha P., Clements V.K., Bunt S.K., Albelda S.M., Ostrand-Rosenberg S. Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J. Immunol. 2007, 179:977-983.
    • (2007) J. Immunol. , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 150
    • 0034472617 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor invasion and metastasis
    • Stamenkovic I. Matrix metalloproteinases in tumor invasion and metastasis. Semin. Cancer Biol. 2000, 10:415-433.
    • (2000) Semin. Cancer Biol. , vol.10 , pp. 415-433
    • Stamenkovic, I.1
  • 151
    • 0031785376 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and its receptors is regulated in eyes with intra-ocular tumors
    • Stitt A.W., Simpson D.A., Boocock C., Gardiner T.A., Murphy G.M., Archer D.B. Expression of vascular endothelial growth factor (VEGF) and its receptors is regulated in eyes with intra-ocular tumors. J. Pathol. 1998, 186:306-312.
    • (1998) J. Pathol. , vol.186 , pp. 306-312
    • Stitt, A.W.1    Simpson, D.A.2    Boocock, C.3    Gardiner, T.A.4    Murphy, G.M.5    Archer, D.B.6
  • 153
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectivity eliminates splenic Gr1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances anti-tumor immune activity
    • Suzuki E., Kapoor V., Jassar A.S., Kaiser L.R., Albelda S.M. Gemcitabine selectivity eliminates splenic Gr1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances anti-tumor immune activity. Clin. Cancer Res. 2005, 11:6713-6721.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 154
    • 36148960830 scopus 로고    scopus 로고
    • Inflammatory cell infiltration of tumors: Jekyll or Hyde
    • Talmadge J.E., Donkor M., Scholar E. Inflammatory cell infiltration of tumors: Jekyll or Hyde. Cancer Metastasis Rev. 2007, 26:373-400.
    • (2007) Cancer Metastasis Rev. , vol.26 , pp. 373-400
    • Talmadge, J.E.1    Donkor, M.2    Scholar, E.3
  • 155
    • 0242551508 scopus 로고    scopus 로고
    • Metchnikoff and the phagocytosis theory
    • Tauber A.I. Metchnikoff and the phagocytosis theory. Nat. Rev. Mol. Cell Biol. 2003, 4:897-901.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 897-901
    • Tauber, A.I.1
  • 156
    • 0347988288 scopus 로고    scopus 로고
    • Microcirculation and tumor-infiltrating macrophages in choroidal and ciliary body melanoma and corresponding metastases
    • Toivonen P., Mäkitie T., Kujala E., Kivelä T. Microcirculation and tumor-infiltrating macrophages in choroidal and ciliary body melanoma and corresponding metastases. Invest. Ophthalmol. Vis. Sci. 2004, 45:1-6.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 1-6
    • Toivonen, P.1    Mäkitie, T.2    Kujala, E.3    Kivelä, T.4
  • 157
    • 0034650795 scopus 로고    scopus 로고
    • Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalfa and IL-1a
    • Torisu H., Ono M., Kiryu H., Furue M., Ohmoto Y., Nakayama J., Nishioka Y., Sone S., Kuwano M. Macrophage infiltration correlates with tumor stage and angiogenesis in human malignant melanoma: possible involvement of TNFalfa and IL-1a. Int. J. Cancer 2000, 85:182-188.
    • (2000) Int. J. Cancer , vol.85 , pp. 182-188
    • Torisu, H.1    Ono, M.2    Kiryu, H.3    Furue, M.4    Ohmoto, Y.5    Nakayama, J.6    Nishioka, Y.7    Sone, S.8    Kuwano, M.9
  • 161
    • 0028111256 scopus 로고
    • Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications
    • Van Rooijen N., Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J. Immunol. Methods 1994, 174:83-93.
    • (1994) J. Immunol. Methods , vol.174 , pp. 83-93
    • Van Rooijen, N.1    Sanders, A.2
  • 162
    • 0029885195 scopus 로고    scopus 로고
    • Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine
    • Van Rooijen N., Sanders A., van den Berg T.K. Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine. J. Immunol. Methods 1996, 193:93-99.
    • (1996) J. Immunol. Methods , vol.193 , pp. 93-99
    • Van Rooijen, N.1    Sanders, A.2    van den Berg, T.K.3
  • 166
    • 78650648668 scopus 로고    scopus 로고
    • CTL induction of tumoricidal nitric oxide production by intratumoral macrophages is critical for tumor elimination
    • Vicetti Miguel R.D., Cherpes T.L., Watson L.J., McKenna K.C. CTL induction of tumoricidal nitric oxide production by intratumoral macrophages is critical for tumor elimination. J. Immunol. 2010, 185:6706-6718. 10.4049/jimmunol.0903411.
    • (2010) J. Immunol. , vol.185 , pp. 6706-6718
    • Vicetti Miguel, R.D.1    Cherpes, T.L.2    Watson, L.J.3    McKenna, K.C.4
  • 167
    • 33750066023 scopus 로고    scopus 로고
    • Involvement of HIF-1 in invasion of Mum2B uveal melanoma cells
    • Victor N., Ivy A., Jiang B.-H., Agani F.H. Involvement of HIF-1 in invasion of Mum2B uveal melanoma cells. Clin. Exp. Metastasis 2006, 23:87-96.
    • (2006) Clin. Exp. Metastasis , vol.23 , pp. 87-96
    • Victor, N.1    Ivy, A.2    Jiang, B.-H.3    Agani, F.H.4
  • 168
    • 0028879632 scopus 로고
    • Blood-ocular barrier breakdown in eyes with ocular melanoma. A potential role for vascular endothelial growth factor/permeability factor
    • Vinores S.A., Kuchle M., Mahlow J., et al. Blood-ocular barrier breakdown in eyes with ocular melanoma. A potential role for vascular endothelial growth factor/permeability factor. Am. J. Pathol. 1995, 147:1289-1297.
    • (1995) Am. J. Pathol. , vol.147 , pp. 1289-1297
    • Vinores, S.A.1    Kuchle, M.2    Mahlow, J.3
  • 169
    • 0020674421 scopus 로고
    • Prognostic role of morphological characteristics of the immune response in uveal melanoblastomas of various types
    • Vit V.V. Prognostic role of morphological characteristics of the immune response in uveal melanoblastomas of various types. Arkh. Patol. 1983, 45:25-30.
    • (1983) Arkh. Patol. , vol.45 , pp. 25-30
    • Vit, V.V.1
  • 170
    • 0042333471 scopus 로고    scopus 로고
    • Role of TRAIL and IFN gamma in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye
    • Wang S., Boonman Z.F.H.M., Li H.-C., He Y.-G., Jager M.J., Toes R.E.M., Niederkorn J.Y. Role of TRAIL and IFN gamma in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye. J. Immunol. 2003, 171:2789-2796.
    • (2003) J. Immunol. , vol.171 , pp. 2789-2796
    • Wang, S.1    Boonman, Z.F.H.M.2    Li, H.-C.3    He, Y.-G.4    Jager, M.J.5    Toes, R.E.M.6    Niederkorn, J.Y.7
  • 173
    • 2342514113 scopus 로고    scopus 로고
    • Evidence of macrophage and lymphocyte, but not dendritic cell, infiltration in posterior uveal melanomas, whilst cultured uveal melanomas demonstrate pluritotency by expressing CD68 and CD163
    • Woodward J., Sisley K., Reeves G., Nichols C., Parsons M.A., Mudhar H., Rennie I. Evidence of macrophage and lymphocyte, but not dendritic cell, infiltration in posterior uveal melanomas, whilst cultured uveal melanomas demonstrate pluritotency by expressing CD68 and CD163. Int. J. Exp. Pathol. 2004, 85:35-43.
    • (2004) Int. J. Exp. Pathol. , vol.85 , pp. 35-43
    • Woodward, J.1    Sisley, K.2    Reeves, G.3    Nichols, C.4    Parsons, M.A.5    Mudhar, H.6    Rennie, I.7
  • 175
    • 77953259280 scopus 로고    scopus 로고
    • Bevacizumab suppresses establishment of micrometastases of experimental ocular melanoma
    • Yang H., Jager M.J., Grossniklaus H.E. Bevacizumab suppresses establishment of micrometastases of experimental ocular melanoma. Invest. Ophthalmol. Vis. Sci. 2010, 51:2835-2842.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 2835-2842
    • Yang, H.1    Jager, M.J.2    Grossniklaus, H.E.3
  • 176
    • 0027890917 scopus 로고
    • Inhibition of tumor production of granulocyte-macrophage colony-stimulating factor by 1 alpha, 25-dihydroxyvitamin D3 reduces tumor motility and metastasis
    • Young M.R., Halpin J., Hussain R., Lozano Y., Djordjevic A., Devata S., Matthews J.P., Wright M.A. Inhibition of tumor production of granulocyte-macrophage colony-stimulating factor by 1 alpha, 25-dihydroxyvitamin D3 reduces tumor motility and metastasis. Invasion Metastasis 1993, 13:169-177.
    • (1993) Invasion Metastasis , vol.13 , pp. 169-177
    • Young, M.R.1    Halpin, J.2    Hussain, R.3    Lozano, Y.4    Djordjevic, A.5    Devata, S.6    Matthews, J.P.7    Wright, M.A.8


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