Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine

Journal of Immunological Methods

Volumn 193, Issue 1, 1996, Pages 93-99

  Van Rooijen, Nico ^a   Sanders, Annemarie ^a   Van Den Berg, Timo K ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Apoptosis; Clodronate; Liposome; Macrophage; Propamidine

Indexed keywords

CLODRONIC ACID; EDETIC ACID; LIPOSOME; PROPAMIDINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; FEMALE; IN VITRO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

ANIMALIA;

EID: 0029885195     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-1759(96)00056-7     Document Type: Article

References (21)

1. 2 MBP-liposomes: Depletion kinetics and accelerated repopulation of peritoneal and omental macrophages by administration of Freund's adjuvant. Cell Tissue Res. 280, 189-196.
2. Conte, M.R., Jenkins, T.C. and Lane, A.N. (1995) Interaction of minor-groove-binding diamidine ligands with an asymmetric DNA duplex. NMR and molecular modelling studies. Eur. J. Biochem. 229, 433-444.
3. Cotter, T.G. and Al-Rubeai, M. (1995) Cell death (apoptosis) in cell culture systems. Trends Biotechnol. 13, 150-155.
4. Edwards, K.J., Jenkins, T.C. and Neidle, S. (1992) Crystal structure of a pentamidine-oligonucleotide complex: Implications for DNA-binding properties. Biochemistry 31, 7104-7109.
5. Fleisch, H. (1988) Bisphosphonates: a new class of drugs in diseases of bone and calcium metabolism. Handb. Exp. Pharmacol. 83, 441-466.
6. Gambari, R. and Nastruzzi, C. (1994) DNA-binding activity and biological effects of aromatic polyamides. Biochem. Pharmacol. 47, 599-610.
7. Hileti, D., Panayiotidis, P. and Hoffbrand, A.V. (1995) Iron chelators induce apoptosis in proliferating cells. Br. J. Haematol. 89, 181-187.
8. Kabakov, A.E. and Gabai, G.L. (1994) Heat-shock proteins main-tain the viability of ATP-deprived cells: What is the mechanism? Trends Cell Biol. 4, 193-196.
9. Nicoletti, I., Migliorati, G., Pagliacci, M.C., Grignani, F. and Riccardi, C. (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139, 271-279.
10. Nunn, C.M. and Neidle, S. (1995) Sequence-dependent drug binding to the minor groove of DNA: Crystal structure of the DNA Dodecamer d(CGCAAATTTGCG)2 complexed with propamidine. J. Med. Chem. 38, 2317-2325.
11. Nunn, C.M., Jenkins, T.C. and Neidle, S. (1993) Crystal structure of d(CGCGAATTCGCG) complexed with propamidine, a short-chain homologue of the drug pentamidine. Biochemistry 32, 13838-13843.
12. Ormerod, M.G., Collins, M.K.L., Rodriguez-Tarduchy, G. and Robertson, D. (1992) Apoptosis in interleukin-3-dependent haemopoietic cells. Quantification by two flow cytometric methods. J. Immunol. Methods 153, 57-65.
13. Perrine, D., Chenu, J.P., Georges, P., Lancelot, J.C., Saturnino, C. and Robba, M. (1995) Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga. Antimicrob. Agents Chemother. 39, 339-342.
14. Raschke, W.C., Baird, S., Ralph, P. and Nakoinz, I. (1978) Functional macrophage cell lines transformed by Abelson leukemia virus. Cell 15, 261-267.
15. Van Rooijen, N. (1993) Extracellular and intracellular action of clodronate in osteolytic bone diseases: A hypothesis. Calcif. Tissue Intern. 52, 407-410.
16. Van Rooijen, N. and Poppema, A. (1992) Efficacy of various water soluble chelator molecules in the liposome mediated macrophage 'suicide' technique. J. Pharmacol. Methods 28, 217-221.
17. Van Rooijen, N. and Sanders, A. (1994) Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications. J. Immunol. Methods 174, 83-93.
18. Van Rooijen, N. and Sanders, A. (1996) Kupffer cell depletion by liposome-delivered drugs: Comparative activity of intracellular clodronate, propamidine and ethylenediaminotetraacetic acid (EDTA). Hepatology, in press.
19. Van Rooijen, N., Kors, N., Ter Hart, H. and Claassen, E. (1988) In vitro and in vivo elimination of macrophage tumor cells using liposome-encapsulated dichloromethylene-diphosphonate. Virchows Arch. B (Cell Pathol.) 54, 241-245.
20. Van Rooijen, N., Bakker, J., Sanders, A. and Mellink, J. (1995) Killing of Entamoeba invadens using liposome-encapsulated drugs. Parasitol. Res. 81, 258-261.
21. Wolfe, J.T., Ross, D. and Cohen, G.M. (1994) A role for metals and free radicals in the induction of apoptosis in thymocytes, FEBS Lett. 352, 58-62.