Microvessel count predicts survival in uveal melanoma

Cancer Research

Volumn 56, Issue 13, 1996, Pages 2900-2903

  Foss, Alexander J E ^a   Alexander, Robert A ^a   Jefferies, Lee W ^a   Hungerford, John L ^b   Harris, Adrian L ^c   Lightman, Susan ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MOORFIELDS EYE HOSPITAL   (United Kingdom)

^c CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8;

ADJUVANT THERAPY; ADULT; ANGIOGENESIS; ARTICLE; CANCER SURVIVAL; FEMALE; HIGH RISK POPULATION; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RELIABILITY; TUMOR GROWTH; UVEA MELANOMA;

FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MALE; MELANOMA; NEOVASCULARIZATION, PATHOLOGIC; PARAFFIN EMBEDDING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; STAINING AND LABELING; TUMOR MARKERS, BIOLOGICAL; VON WILLEBRAND FACTOR;

EID: 0030014569     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Folkman, J. What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst., 82: 4-6, 1990.
2. Folkman, J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med., 1: 27-31, 1995.
3. Craft, P S , and Harris, A. L. Clinical prognostic significance of rumour angiogenesis. Ann. Oncol , 5 305-311, 1994.
4. Srivastava, A , Laidler, P., Hughes, L E., Woodcock, J., and Shedden, E. J. Neovascularisation in human cutaneous melanoma: a quantitative morphological and Doppler ultrasound study Eur. J. Cancer Clin. Oncol., 22: 1205-1209, 1986.
5. Fallowfield, M. E., and Cook, M. G The vascularity of primary cutaneous melanoma. J. Pathol., 164 241-244, 1991.
6. Barnhill, R L , and Levy, M A. Regressing thin cutaneous malignant melanomas (≤1.0 mm) are associated with angiogenesis. Am J Pathol., 143: 99-104, 1993.
7. Barnhill, R. L , Fandrey, K., Levy, M A., Mihm, M C , Jr., and Hyman, B. Angiogenesis and tumor progression of melanoma: quantification of vascularity in melanocytic nevi and cutaneous malignant melanoma. Lab. Invest , 67: 331-337, 1992
8. Graham, C. H., Rivers, J , Kerbel, R. S , Stankiewicz, K. S , and White, W. L. Extent of vascularization as a prognostic indicator in thin (<0.76 mm) malignant melanomas Am. J. Pathol , 145: 510-514, 1994.
9. Barnhill, R. L , Busam, K J., Berwick, M., Blessing, K., Cochran, A. J., Elder, D. E., Fandrey, K., Karaoli, T., and White, W L. Tumour vascularity is not a prognostic factor for cutaneous melanoma. Lancet, 344: 1237-1238, 1994
10. Smolle, J , Soyer, H P., Hofmann-Wellenhof, R , Smolle-Juettner, F. M., and Kerl, H. Vascular architecture of melanocytic skin tumors: a quantitative immunohistochemical study using automated image analysis Pathol. Res. Pract., 185: 740-745, 1989.
11. Carnochan, P., Briggs, J C , Westbury, G , and Davies, A. J. S. The vascularity of cutaneous melanoma: a quantitative histological study of lesions 0 85-1 25 mm in thickness. Br. J. Cancer, 64: 102-107, 1991
12. Srivastava, A., Laidler, P , Davies, R. P., Horgan, K., and Hughes, L. E The prognostic significance of tumor vascularity in intermediate thickness (0.76-4.00-mm thick) skin melanoma, a quantitative histologic study. Am. J Pathol., 133: 419-423, 1988.
13. Folberg, R., Rummelt, V , Parys Van Ginderdeuren, R., Hwang, T., Woolson, R. F., Pe'er, J. and Gruman, L M. The prognostic value of tumor blood vessel morphology in primary uveal melanoma. Ophthalmology, 100: 1389-1398, 1993
14. Folberg, R. Tumor progression in ocular melanomas. J Invest Dermatol., 100: 326S-331S, 1993.
15. Folberg, R., Pe'er, J., Gruman, L. M., Woolson, R. F., Jeng, G., Montague, P. R., Moninger, T. O., Yi, H., and Moore, K. C The morphologic characteristics of tumor blood vessels as a marker of tumor progression in primary human uveal melanoma: a matched case-control study. Hum. Pathol , 23: 1298-1305, 1992.
16. Rummelt, V., Folberg, R , Rummelt, C., Gruman, L. M., Hwang, T., Woolson, R. F., Yi, H., and Naumann, G. O. Microcirculation architecture of melanocytic nevi and malignant melanomas of the ciliary body and choroid, a comparative histopathologic and ultrastructural study. Ophthalmology, 101: 718-727, 1994.
17. Rummelt, V., Folberg, R., Woolson, R F., Hwang, T., and Pe'er, J. Relation between microcirculation architecture and the aggressive behaviour of ciliary body melanomas. Ophthalmology, 102: 844-851, 1995.
18. Foss, A. J. E , Alexander, R. A., Jefferies, L. W., and Lightman, S. L. The effect of melanin bleaching on immunohistochemical techniques. Br J. Biomed. Sci., 52: 22-25, 1995.
19. Pe'er, J., Rummelt, V., Mawn, L., Hwang, T., Woolson, R. F., and Folberg, R. Mean of the ten largest nucleoli, microcirculation architecture, and prognosis of ciliochoroidal melanomas. Ophthalmology, 101: 1227-1235, 1994.
20. Bernsen, H. J. J A , Rijken, P. F. J. W., Oostendorp, T., and van der Kogel, A. J Vascularity and perfusion of human gliomas xenografted in the athymic nude mouse. Br. J. Cancer, 71: 721-726, 1995.