메뉴 건너뛰기




Volumn 185, Issue 11, 2010, Pages 6706-6718

CTL induction of tumoricidal nitric oxide production by intratumoral macrophages is critical for tumor elimination

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

EID: 78650648668     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903411     Document Type: Article
Times cited : (32)

References (53)
  • 1
    • 0242636366 scopus 로고    scopus 로고
    • Ocular immune privilege: Therapeutic opportunities from an experiment of nature
    • Streilein, J. W. 2003. Ocular immune privilege: therapeutic opportunities from an experiment of nature. Nat. Rev. Immunol. 3:879-889.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 879-889
    • Streilein, J.W.1
  • 2
    • 33645107513 scopus 로고    scopus 로고
    • See no evil, hear no evil, do no evil: The lessons of immune privilege
    • Niederkorn, J. Y. 2006. See no evil, hear no evil, do no evil: the lessons of immune privilege. Nat. Immunol. 7:354-359.
    • (2006) Nat. Immunol. , vol.7 , pp. 354-359
    • Niederkorn, J.Y.1
  • 3
    • 67651183589 scopus 로고    scopus 로고
    • Immune escape mechanisms of intraocular tumors
    • Niederkorn, J. Y. 2009. Immune escape mechanisms of intraocular tumors. Prog. Retin. Eye Res. 28:329-347.
    • (2009) Prog. Retin. Eye Res. , vol.28 , pp. 329-347
    • Niederkorn, J.Y.1
  • 4
    • 0019413126 scopus 로고
    • Deviant immune responses to allogeneic tumors injected intracamerally and subcutaneously in mice
    • Niederkorn, J. Y., J. W. Streilein, and J. A. Shadduck. 1981. Deviant immune responses to allogeneic tumors injected intracamerally and subcutaneously in mice. Invest. Ophthalmol. Vis. Sci. 20:355-363.
    • (1981) Invest. Ophthalmol. Vis. Sci. , vol.20 , pp. 355-363
    • Niederkorn, J.Y.1    Streilein, J.W.2    Shadduck, J.A.3
  • 5
    • 33746214824 scopus 로고    scopus 로고
    • Accumulation of immunosuppressive CD11b+ myeloid cells correlates with the failure to prevent tumor growth in the anterior chamber of the eye
    • McKenna, K. C., and J. A. Kapp. 2006. Accumulation of immunosuppressive CD11b+ myeloid cells correlates with the failure to prevent tumor growth in the anterior chamber of the eye. J. Immunol. 177:1599-1608.
    • (2006) J. Immunol. , vol.177 , pp. 1599-1608
    • McKenna, K.C.1    Kapp, J.A.2
  • 6
    • 0021073187 scopus 로고
    • Alloantigens placed into the anterior chamber of the eye induce specific suppression of delayed-type hypersensitivity but normal cytotoxic T lymphocyte and helper T lymphocyte responses
    • Niederkorn, J. Y., and J. W. Streilein. 1983. Alloantigens placed into the anterior chamber of the eye induce specific suppression of delayed-type hypersensitivity but normal cytotoxic T lymphocyte and helper T lymphocyte responses. J. Immunol. 131:2670-2674.
    • (1983) J. Immunol. , vol.131 , pp. 2670-2674
    • Niederkorn, J.Y.1    Streilein, J.W.2
  • 7
    • 0024592176 scopus 로고
    • Analysis of cytotoxic T cell responses to intracameral allogeneic tumors
    • Ksander, B. R., and J. W. Streilein. 1989. Analysis of cytotoxic T cell responses to intracameral allogeneic tumors. Invest. Ophthalmol. Vis. Sci. 30:323-329.
    • (1989) Invest. Ophthalmol. Vis. Sci. , vol.30 , pp. 323-329
    • Ksander, B.R.1    Streilein, J.W.2
  • 8
    • 0021079461 scopus 로고
    • Intracamerally induced concomitant immunity: Mice harboring progressively growing intraocular tumors are immune to spontaneous metastases and secondary tumor challenge
    • Niederkorn, J. Y., and J. W. Streilein. 1983. Intracamerally induced concomitant immunity: mice harboring progressively growing intraocular tumors are immune to spontaneous metastases and secondary tumor challenge. J. Immunol. 131:2587-2594.
    • (1983) J. Immunol. , vol.131 , pp. 2587-2594
    • Niederkorn, J.Y.1    Streilein, J.W.2
  • 10
    • 0026598380 scopus 로고
    • Infiltrating lymphocytes and antigen expression in uveal melanoma
    • Meecham, W. J., D. H. Char, and S. Kaleta-Michaels. 1992. Infiltrating lymphocytes and antigen expression in uveal melanoma. Ophthalmic Res. 24:20-26.
    • (1992) Ophthalmic Res. , vol.24 , pp. 20-26
    • Meecham, W.J.1    Char, D.H.2    Kaleta-Michaels, S.3
  • 11
    • 33745312287 scopus 로고    scopus 로고
    • Tumor escape mutants develop within an immune-privileged environment in the absence of T cell selection
    • Chen, P. W., T. Uno, and B. R. Ksander. 2006. Tumor escape mutants develop within an immune-privileged environment in the absence of T cell selection. J. Immunol. 177:162-168.
    • (2006) J. Immunol. , vol.177 , pp. 162-168
    • Chen, P.W.1    Uno, T.2    Ksander, B.R.3
  • 13
  • 14
    • 0036839216 scopus 로고    scopus 로고
    • TRAIL: A mechanism of tumor surveillance in an immune privileged site
    • Lee, H. O., J. M. Herndon, R. Barreiro, T. S. Griffith, and T. A. Ferguson. 2002. TRAIL: a mechanism of tumor surveillance in an immune privileged site. J. Immunol. 169:4739-4744.
    • (2002) J. Immunol. , vol.169 , pp. 4739-4744
    • Lee, H.O.1    Herndon, J.M.2    Barreiro, R.3    Griffith, T.S.4    Ferguson, T.A.5
  • 16
    • 0033104693 scopus 로고    scopus 로고
    • Control of syngeneic tumor growth by activation of CD8+ T cells: Efficacy is limited by migration away from the site and induction of nonresponsiveness
    • Shrikant, P., and M. F. Mescher. 1999. Control of syngeneic tumor growth by activation of CD8+ T cells: efficacy is limited by migration away from the site and induction of nonresponsiveness. J. Immunol. 162:2858-2866.
    • (1999) J. Immunol. , vol.162 , pp. 2858-2866
    • Shrikant, P.1    Mescher, M.F.2
  • 17
    • 0031930924 scopus 로고    scopus 로고
    • Uveal melanomas contain antigenically specific and nonspecific infiltrating lymphocytes
    • Ksander, B. R., D. C. Geer, P. W. Chen, M. L. Salgaller, P. Rubsamen, and T. G. Murray. 1998. Uveal melanomas contain antigenically specific and nonspecific infiltrating lymphocytes. Curr. Eye Res. 17:165-173.
    • (1998) Curr. Eye Res. , vol.17 , pp. 165-173
    • Ksander, B.R.1    Geer, D.C.2    Chen, P.W.3    Salgaller, M.L.4    Rubsamen, P.5    Murray, T.G.6
  • 20
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich, D. I., and S. Nagaraj. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9:162-174.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 21
    • 0034994770 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages (CD68 (+) cells) and prognosis in malignant uveal melanoma
    • Mäkitie, T., P. Summanen, A. Tarkkanen, and T. Kivelä. 2001. Tumor-infiltrating macrophages (CD68 (+) cells) and prognosis in malignant uveal melanoma. Invest. Ophthalmol. Vis. Sci. 42:1414-1421.
    • (2001) Invest. Ophthalmol. Vis. Sci. , vol.42 , pp. 1414-1421
    • Mäkitie, T.1    Summanen, P.2    Tarkkanen, A.3    Kivelä, T.4
  • 22
    • 33747803970 scopus 로고    scopus 로고
    • IFN-gamma regulates donor CD8 T cell expansion, migration, and leads to apoptosis of cells of a solid tumor
    • Hollenbaugh, J. A., and R. W. Dutton. 2006. IFN-gamma regulates donor CD8 T cell expansion, migration, and leads to apoptosis of cells of a solid tumor. J. Immunol. 177:3004-3011.
    • (2006) J. Immunol. , vol.177 , pp. 3004-3011
    • Hollenbaugh, J.A.1    Dutton, R.W.2
  • 24
    • 0023821578 scopus 로고
    • Introduction of soluble protein into the class I pathway of antigen processing and presentation
    • Moore, M. W., F. R. Carbone, and M. J. Bevan. 1988. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 54:777-785.
    • (1988) Cell. , vol.54 , pp. 777-785
    • Moore, M.W.1    Carbone, F.R.2    Bevan, M.J.3
  • 27
    • 3242771187 scopus 로고    scopus 로고
    • The rate of the CD8-dependent initial reduction in tumor volume is not limited by contact-dependent perforin, Fas ligand, or TNF-mediated cytolysis
    • Hollenbaugh, J. A., J. Reome, M. Dobrzanski, and R. W. Dutton. 2004. The rate of the CD8-dependent initial reduction in tumor volume is not limited by contact-dependent perforin, Fas ligand, or TNF-mediated cytolysis. J. Immunol. 173:1738-1743.
    • (2004) J. Immunol. , vol.173 , pp. 1738-1743
    • Hollenbaugh, J.A.1    Reome, J.2    Dobrzanski, M.3    Dutton, R.W.4
  • 28
    • 0032519412 scopus 로고    scopus 로고
    • TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells
    • Takeuchi, M., P. Alard, and J. W. Streilein. 1998. TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells. J. Immunol. 160:1589-1597.
    • (1998) J. Immunol. , vol.160 , pp. 1589-1597
    • Takeuchi, M.1    Alard, P.2    Streilein, J.W.3
  • 29
    • 1642576227 scopus 로고    scopus 로고
    • Tumor cell-derived nitric oxide is involved in the immune-rejection of an immunogenic murine lymphoma
    • Hu, D. E., S. O. Dyke, A. M. Moore, L. L. Thomsen, and K. M. Brindle. 2004. Tumor cell-derived nitric oxide is involved in the immune-rejection of an immunogenic murine lymphoma. Cancer Res. 64:152-161.
    • (2004) Cancer Res. , vol.64 , pp. 152-161
    • Hu, D.E.1    Dyke, S.O.2    Moore, A.M.3    Thomsen, L.L.4    Brindle, K.M.5
  • 30
    • 33947513298 scopus 로고    scopus 로고
    • Ocular immunosuppressive microenvironment
    • Taylor, A. W. 2007. Ocular immunosuppressive microenvironment. Chem. Immunol. Allergy 92:71-85.
    • (2007) Chem. Immunol. Allergy , vol.92 , pp. 71-85
    • Taylor, A.W.1
  • 31
    • 73049125323 scopus 로고
    • Immune mechanisms in homotransplantation. II. Quantitative assay of the immunologic activity of lymphoid cells stimulated by tumor homografts
    • Winn, H. J. 1961. Immune mechanisms in homotransplantation. II. Quantitative assay of the immunologic activity of lymphoid cells stimulated by tumor homografts. J. Immunol. 86:228-239.
    • (1961) J. Immunol. , vol.86 , pp. 228-239
    • Winn, H.J.1
  • 32
    • 0027724472 scopus 로고
    • Complete elimination ('cure') of progressively growing intraocular tumors by local injection of tumor-specific CD8+ T lymphocytes
    • Miki, S., B. Ksander, and J. W. Streilein. 1993. Complete elimination ('cure') of progressively growing intraocular tumors by local injection of tumor-specific CD8+ T lymphocytes. Invest. Ophthalmol. Vis. Sci. 34:3622-3634.
    • (1993) Invest. Ophthalmol. Vis. Sci. , vol.34 , pp. 3622-3634
    • Miki, S.1    Ksander, B.2    Streilein, J.W.3
  • 35
    • 0023177782 scopus 로고
    • Destructive and nondestructive patterns of immune rejection of syngeneic intraocular tumors
    • Knisely, T. L., M. W. Luckenbach, B. J. Fischer, and J. Y. Niederkorn. 1987. Destructive and nondestructive patterns of immune rejection of syngeneic intraocular tumors. J. Immunol. 138:4515-4523.
    • (1987) J. Immunol. , vol.138 , pp. 4515-4523
    • Knisely, T.L.1    Luckenbach, M.W.2    Fischer, B.J.3    Niederkorn, J.Y.4
  • 36
    • 0031779801 scopus 로고    scopus 로고
    • Suppression of nitric oxide generated by inflammatory macrophages by calcitonin gene-related peptide in aqueous humor
    • Taylor, A. W., D. G. Yee, and J. W. Streilein. 1998. Suppression of nitric oxide generated by inflammatory macrophages by calcitonin gene-related peptide in aqueous humor. Invest. Ophthalmol. Vis. Sci. 39:1372-1378.
    • (1998) Invest. Ophthalmol. Vis. Sci. , vol.39 , pp. 1372-1378
    • Taylor, A.W.1    Yee, D.G.2    Streilein, J.W.3
  • 37
    • 0035844305 scopus 로고    scopus 로고
    • Sustained nitric oxide production in macrophages requires the arginine transporter CAT2
    • Nicholson, B., C. K. Manner, J. Kleeman, and C. L. MacLeod. 2001. Sustained nitric oxide production in macrophages requires the arginine transporter CAT2. J. Biol. Chem. 276:15881-15885.
    • (2001) J. Biol. Chem. , vol.276 , pp. 15881-15885
    • Nicholson, B.1    Manner, C.K.2    Kleeman, J.3    MacLeod, C.L.4
  • 38
    • 0032926256 scopus 로고    scopus 로고
    • Expression of the inducible NO synthase in human monocytic U937 cells allows high output nitric oxide production
    • Bertholet, S., E. Tzeng, E. Felley-Bosco, and J. Mauël. 1999. Expression of the inducible NO synthase in human monocytic U937 cells allows high output nitric oxide production. J. Leukoc. Biol. 65:50-58.
    • (1999) J. Leukoc. Biol. , vol.65 , pp. 50-58
    • Bertholet, S.1    Tzeng, E.2    Felley-Bosco, E.3    Mauël, J.4
  • 39
    • 34249818191 scopus 로고    scopus 로고
    • Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling
    • Mori, M. 2007. Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling. J. Nutr. 137 (6, Suppl 2) 1616S-1620S.
    • (2007) J. Nutr. , vol.137 , Issue.2-6 SUPPL.
    • Mori, M.1
  • 40
    • 0036433224 scopus 로고    scopus 로고
    • Arginase expression and modulation of IL-1beta-induced nitric oxide generation in rat and human islets of Langerhans
    • Stickings, P., S. K. Mistry, J. L. Boucher, S. M. Morris, and J. M. Cunningham. 2002. Arginase expression and modulation of IL-1beta-induced nitric oxide generation in rat and human islets of Langerhans. Nitric Oxide 7:289-296.
    • (2002) Nitric Oxide , vol.7 , pp. 289-296
    • Stickings, P.1    Mistry, S.K.2    Boucher, J.L.3    Morris, S.M.4    Cunningham, J.M.5
  • 41
    • 0027441142 scopus 로고
    • Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme
    • Baek, K. J., B. A. Thiel, S. Lucas, and D. J. Stuehr. 1993. Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme. J. Biol. Chem. 268:21120-21129.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21120-21129
    • Baek, K.J.1    Thiel, B.A.2    Lucas, S.3    Stuehr, D.J.4
  • 42
    • 0035167841 scopus 로고    scopus 로고
    • MIP-2 recruits NKT cells to the spleen during tolerance induction
    • Faunce, D. E., K. H. Sonoda, and J. Stein-Streilein. 2001. MIP-2 recruits NKT cells to the spleen during tolerance induction. J. Immunol. 166:313-321.
    • (2001) J. Immunol. , vol.166 , pp. 313-321
    • Faunce, D.E.1    Sonoda, K.H.2    Stein-Streilein, J.3
  • 43
    • 17044366637 scopus 로고    scopus 로고
    • STAT1 signaling regulates tumorassociated macrophage-mediated T cell deletion
    • Kusmartsev, S., and D. I. Gabrilovich. 2005. STAT1 signaling regulates tumorassociated macrophage-mediated T cell deletion. J. Immunol. 174:4880-4891.
    • (2005) J. Immunol. , vol.174 , pp. 4880-4891
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 46
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • Sinha, P., V. K. Clements, S. K. Bunt, S. M. Albelda, and S. Ostrand-Rosenberg. 2007. Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J. Immunol. 179:977-983.
    • (2007) J. Immunol. , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 47
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn, J. I., S. Nagaraj, M. Collazo, and D. I. Gabrilovich. 2008. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 181:5791-5802.
    • (2008) J. Immunol. , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 48
    • 0021925081 scopus 로고
    • Characterization of the suppressor cell (s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells
    • Streilein, J. W., and J. Y. Niederkorn. 1985. Characterization of the suppressor cell (s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells. J. Immunol. 134:1381-1387.
    • (1985) J. Immunol. , vol.134 , pp. 1381-1387
    • Streilein, J.W.1    Niederkorn, J.Y.2
  • 49
    • 0021885429 scopus 로고
    • Spontaneous immune rejection of intraocular tumors in mice
    • Niederkorn, J. Y., and P. C. Meunier. 1985. Spontaneous immune rejection of intraocular tumors in mice. Invest. Ophthalmol. Vis. Sci. 26:877-884.
    • (1985) Invest. Ophthalmol. Vis. Sci. , vol.26 , pp. 877-884
    • Niederkorn, J.Y.1    Meunier, P.C.2
  • 51
    • 0042333471 scopus 로고    scopus 로고
    • Role of TRAIL and IFN-gamma in CD4+ T celldependent tumor rejection in the anterior chamber of the eye
    • Wang, S., Z. F. Boonman, H. C. Li, Y. He, M. J. Jager, R. E. Toes, and J. Y. Niederkorn. 2003. Role of TRAIL and IFN-gamma in CD4+ T celldependent tumor rejection in the anterior chamber of the eye. J. Immunol. 171:2789-2796.
    • (2003) J. Immunol. , vol.171 , pp. 2789-2796
    • Wang, S.1    Boonman, Z.F.2    Li, H.C.3    He, Y.4    Jager, M.J.5    Toes, R.E.6    Niederkorn, J.Y.7
  • 53
    • 38649095597 scopus 로고    scopus 로고
    • CD4+ T-cell-dependent tumour rejection in an immune-privileged environment requires macrophages
    • Dace, D. S., P. W. Chen, and J. Y. Niederkorn. 2008. CD4+ T-cell-dependent tumour rejection in an immune-privileged environment requires macrophages. Immunology 123:367-377.
    • (2008) Immunology , vol.123 , pp. 367-377
    • Dace, D.S.1    Chen, P.W.2    Niederkorn, J.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.