-
1
-
-
58149173384
-
Homocysteine reduces endothelial progenitor cells in stroke patients through apoptosis
-
Alam MM, Mohamed AA, Shuaib U, Wang C, Ghani U, Schwindt B, Todd KG, Shuaib A (2009) Homocysteine reduces endothelial progenitor cells in stroke patients through apoptosis. J Cerebr Blood F Met 29: 157-165.
-
(2009)
J Cerebr Blood F Met
, vol.29
, pp. 157-165
-
-
Alam, M.M.1
Mohamed, A.A.2
Shuaib, U.3
Wang, C.4
Ghani, U.5
Schwindt, B.6
Todd, K.G.7
Shuaib, A.8
-
2
-
-
0347951237
-
Hyperhomocysteinemia activates nuclear factor-κB in endothelial cells via oxidative stress
-
Au-Yeung KKW, Woo CWH, Sung FL, Yip JCW, Siow YL (2004) Hyperhomocysteinemia activates nuclear factor-κB in endothelial cells via oxidative stress. Circ Res 94: 28-36.
-
(2004)
Circ Res
, vol.94
, pp. 28-36
-
-
Au-Yeung, K.K.W.1
Woo, C.W.H.2
Sung, F.L.3
Yip, J.C.W.4
Siow, Y.L.5
-
3
-
-
68949155456
-
A new DiaSys colorimetric assay for plasma homocysteine: Application in diabetic patients
-
Badiou S, Bariolet S, Dupuy A-M, Sultan A, Avignon A, Cristol J-P (2009) A new DiaSys colorimetric assay for plasma homocysteine: application in diabetic patients. Ann Clin Lab Sci 39: 233-240.
-
(2009)
Ann Clin Lab Sci
, vol.39
, pp. 233-240
-
-
Badiou, S.1
Bariolet, S.2
Dupuy, A.-M.3
Sultan, A.4
Avignon, A.5
Cristol, J.-P.6
-
4
-
-
0036141841
-
Xanthine oxidase - derived reactive oxygen species convert fow-induced arteriolar dilation to constriction in hyperhomocysteinemia: Possible role of peroxynitrite
-
Bagi Z, Ungvari Z, Koller A (2002) Xanthine oxidase - derived reactive oxygen species convert fow-induced arteriolar dilation to constriction in hyperhomocysteinemia: possible role of peroxynitrite. Arterioscl Throm Vas 22: 28-33.
-
(2002)
Arterioscl Throm Vas
, vol.22
, pp. 28-33
-
-
Bagi, Z.1
Ungvari, Z.2
Koller, A.3
-
5
-
-
0034627915
-
Liquid chromatographic assessment of total and protein-bound homocysteine in human plasma
-
Bald E, Kaniowska E, Chwatko G, Glowacki R (2000) Liquid chromatographic assessment of total and protein-bound homocysteine in human plasma. Talanta 50: 1233-1243.
-
(2000)
Talanta
, vol.50
, pp. 1233-1243
-
-
Bald, E.1
Kaniowska, E.2
Chwatko, G.3
Glowacki, R.4
-
6
-
-
33847624075
-
Targeting of metallothionein by l-homocysteine: A novel mechanism for disruption of zinc and redox homeostasis
-
Barbato JC, Catanescu O, Murray K, DiBello PM, Jacobsen DW (2007) Targeting of metallothionein by l-homocysteine: a novel mechanism for disruption of zinc and redox homeostasis. Arterioscl Throm Vas 27: 49-54.
-
(2007)
Arterioscl Throm Vas
, vol.27
, pp. 49-54
-
-
Barbato, J.C.1
Catanescu, O.2
Murray, K.3
Dibello, P.M.4
Jacobsen, D.W.5
-
7
-
-
0037032665
-
Assay of total homocysteine and other thiols by capillary electrophoresis and laser-induced fuorescence detection. II. Pre-analytical and analytical conditions
-
Bayle C, Issac C, Salvayre R, Couderc F, Causse E (2002) Assay of total homocysteine and other thiols by capillary electrophoresis and laser-induced fuorescence detection. II. Pre-analytical and analytical conditions. J Chromatogr A 979: 255-260.
-
(2002)
J Chromatogr A
, vol.979
, pp. 255-260
-
-
Bayle, C.1
Issac, C.2
Salvayre, R.3
Couderc, F.4
Causse, E.5
-
8
-
-
70249108404
-
Oxidative stress upregulates the NMDA receptor on cardiovascular endothelium
-
Betzen C, White R, Zehendner CM, Pietrowski E, Bender B, Luhmann HJ, Kuhlmann CRW (2009) Oxidative stress upregulates the NMDA receptor on cardiovascular endothelium. Free Radical Biol Med 47: 1212-1220.
-
(2009)
Free Radical Biol Med
, vol.47
, pp. 1212-1220
-
-
Betzen, C.1
White, R.2
Zehendner, C.M.3
Pietrowski, E.4
Bender, B.5
Luhmann, H.J.6
Kuhlmann, C.R.W.7
-
9
-
-
0033783020
-
Human serum paraoxonase (pon1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters
-
Billecke S, Draganov D, Counsell R, Stetson P, Watson C, Hsu C, La Du BN (2000) Human serum paraoxonase (pon1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters. Drug Metab Dispos 28: 1335-1342.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1335-1342
-
-
Billecke, S.1
Draganov, D.2
Counsell, R.3
Stetson, P.4
Watson, C.5
Hsu, C.6
La Du, B.N.7
-
10
-
-
1842861601
-
Homocysteine as a neurotoxin in chronic alcoholism
-
Bleich S, Degner D, Sperling W, Bonsch D, Thurauf N, Kornhuber J (2004) Homocysteine as a neurotoxin in chronic alcoholism. Prog Neuro-Psychoph 28: 453-464.
-
(2004)
Prog Neuro-Psychoph
, vol.28
, pp. 453-464
-
-
Bleich, S.1
Degner, D.2
Sperling, W.3
Bonsch, D.4
Thurauf, N.5
Kornhuber, J.6
-
11
-
-
34347335713
-
Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease
-
Boldyrev AA, Johnson P (2007) Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease. J Alzheimers Dis 11: 219-228.
-
(2007)
J Alzheimers Dis
, vol.11
, pp. 219-228
-
-
Boldyrev, A.A.1
Johnson, P.2
-
12
-
-
33645796222
-
Homo-cysteine lowering and cardiovascular events after acute myocardial infarction
-
Bønaa KH, Njølstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T, Wang H, Nordrehaug JE, Arnesen E, Rasmussen K (2006) Homo-cysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med 354: 1578-1588.
-
(2006)
N Engl J Med
, vol.354
, pp. 1578-1588
-
-
Bønaa, K.H.1
Njølstad, I.2
Ueland, P.M.3
Schirmer, H.4
Tverdal, A.5
Steigen, T.6
Wang, H.7
Nordrehaug, J.E.8
Arnesen, E.9
Rasmussen, K.10
-
13
-
-
25644439809
-
Homocysteine and folate metabolism in depression
-
Bottiglieri T (2005) Homocysteine and folate metabolism in depression. Prog Neuro-Psychoph 29: 1103-1112.
-
(2005)
Prog Neuro-Psychoph
, vol.29
, pp. 1103-1112
-
-
Bottiglieri, T.1
-
15
-
-
0022309434
-
The role of S-adenosylhomocysteine in the biological utilization of S-adenosyl-methionine
-
Cantoni GL (1985) The role of S-adenosylhomocysteine in the biological utilization of S-adenosyl-methionine. Prog Clin Biol Res 198: 47-65.
-
(1985)
Prog Clin Biol Res
, vol.198
, pp. 47-65
-
-
Cantoni, G.L.1
-
16
-
-
35349014633
-
Homocysteine induces VCAM-1 gene expression through NF-κB and NAD(P)H oxidase activation: Protective role of Mediterranean diet polyphenolic antioxidants
-
Carluccio MA, Ancora MA, Massaro M, Carluccio M, Scoditti E, Distante A, Storelli C, De Caterina R (2007) Homocysteine induces VCAM-1 gene expression through NF-κB and NAD(P)H oxidase activation: protective role of Mediterranean diet polyphenolic antioxidants. Am J Physiol-Heart C 293: H2344-H2354.
-
(2007)
Am J Physiol-Heart C
, vol.293
-
-
Carluccio, M.A.1
Ancora, M.A.2
Massaro, M.3
Carluccio, M.4
Scoditti, E.5
Distante, A.6
Storelli, C.7
De Caterina, R.8
-
17
-
-
33645666453
-
Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: An overview
-
Castro R, Rivera I, Blom HJ, Jakobs C, Tavares de Almeida I (2006) Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: an overview. J Inherit Metab Dis 29: 3-20.
-
(2006)
J Inherit Metab Dis
, vol.29
, pp. 3-20
-
-
Castro, R.1
Rivera, I.2
Blom, H.J.3
Jakobs, C.4
Tavares de Almeida, I.5
-
18
-
-
18744373039
-
Enzymatic assay of homocysteine on microtiter plates or a TECAN analyzer using crude lysate containing recombinant methionine γ-lyase
-
Chan E-C, Chang P-Y, Wu T-L, Wu JT (2005) Enzymatic assay of homocysteine on microtiter plates or a TECAN analyzer using crude lysate containing recombinant methionine γ-lyase. Ann Clin Lab Sci 35: 155-160.
-
(2005)
Ann Clin Lab Sci
, vol.35
, pp. 155-160
-
-
Chan, E.-C.1
Chang, P.-Y.2
Wu, T.-L.3
Wu, J.T.4
-
19
-
-
42549135938
-
Homocysteine inhibits arterial endothelia cell growth through transcriptional down-regulation of fibroblast growth factor-2 involving G protein and DNA methylation
-
Chang P-Y, Lu S-C, Lee C-M, Chen Y-J, Dugan TA, Huang W-H, Chang S-F, Liao WSL, Chen C-H, Lee Y-T (2008) Homocysteine inhibits arterial endothelia cell growth through transcriptional down-regulation of fibroblast growth factor-2 involving G protein and DNA methylation. Circ Res 102: 933-941.
-
(2008)
Circ Res
, vol.102
, pp. 933-941
-
-
Chang, P.-Y.1
Lu, S.-C.2
Lee, C.-M.3
Chen, Y.-J.4
Dugan, T.A.5
Huang, W.-H.6
Chang, S.-F.7
Liao, W.S.L.8
Chen, C.-H.9
Lee, Y.-T.10
-
20
-
-
38149119817
-
Selective phosphorescence chemosensor for homocysteine based on an iridium (III) complex
-
Chen H, Zhao Q, Wu Y, Li F, Yang H, Yi T, Huang C (2007) Selective phosphorescence chemosensor for homocysteine based on an iridium (III) complex. Inorg Chem 46: 11075-11081.
-
(2007)
Inorg Chem
, vol.46
, pp. 11075-11081
-
-
Chen, H.1
Zhao, Q.2
Wu, Y.3
Li, F.4
Yang, H.5
Yi, T.6
Huang, C.7
-
21
-
-
67650561176
-
The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neu-rotoxin model of Parkinson disease
-
Chigurupati S, Wei Z, Belal C, Vandermey M, Kyriazis GA, Arumugam TV, Chan S (2009) The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neu-rotoxin model of Parkinson disease. J Biol Chem 284: 18323-18333.
-
(2009)
J Biol Chem
, vol.284
, pp. 18323-18333
-
-
Chigurupati, S.1
Wei, Z.2
Belal, C.3
Vandermey, M.4
Kyriazis, G.A.5
Arumugam, T.V.6
Chan, S.7
-
22
-
-
13244287981
-
The determination of homocysteine-thiolactone in human plasma
-
Chwatko G, Jakubowski H (2005) The determination of homocysteine-thiolactone in human plasma. Anal Biochem 337: 271-277.
-
(2005)
Anal Biochem
, vol.337
, pp. 271-277
-
-
Chwatko, G.1
Jakubowski, H.2
-
23
-
-
31344459617
-
B-Vitamin Treatment Trialists' Collaboration: Homocysteine-lowering trials for prevention of cardiovascular events: A review of the design and power of the large randomized trials
-
Clarke R, Armitage J, Lewington S et al (2006) B-Vitamin Treatment Trialists' Collaboration: Homocysteine-lowering trials for prevention of cardiovascular events: a review of the design and power of the large randomized trials. Am Heart J 151: 282-287.
-
(2006)
Am Heart J
, vol.151
, pp. 282-287
-
-
Clarke, R.1
Armitage, J.2
Lewington, S.3
-
24
-
-
0037164104
-
Homocysteine Studies Collaboration: Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis
-
Clarke R, Collins R, Lewington S et al. (2002) Homocysteine Studies Collaboration: Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA 288: 2015-2022.
-
(2002)
JAMA
, vol.288
, pp. 2015-2022
-
-
Clarke, R.1
Collins, R.2
Lewington, S.3
-
25
-
-
0037805185
-
High-performance liquid chromatographic assay for plasma total homocysteine
-
Dai CW, Zhang GS, Wu XP (2002) High-performance liquid chromatographic assay for plasma total homocysteine. Hunan Yi Ke Da Xue Xue Bao 27: 556-558.
-
(2002)
Hunan Yi Ke Da Xue Xue Bao
, vol.27
, pp. 556-558
-
-
Dai, C.W.1
Zhang, G.S.2
Wu, X.P.3
-
26
-
-
0141629314
-
Effect of homocysteine on cytokine production by human endothelial cells and monocytes
-
Dalal S, Parkin SM, Homer-Vanniasinkam S, Nicolaou A (2003) Effect of homocysteine on cytokine production by human endothelial cells and monocytes. Ann Clin Biochem 40: 534-541.
-
(2003)
Ann Clin Biochem
, vol.40
, pp. 534-541
-
-
Dalal, S.1
Parkin, S.M.2
Homer-Vanniasinkam, S.3
Nicolaou, A.4
-
27
-
-
0037277037
-
Quantitative assay of plasma homocysteine thiolactone by gas chromatogra-phy/mass spectrometry
-
Daneshvar P, Yazdanpanah M, Cuthbert C, Cole DE (2003) Quantitative assay of plasma homocysteine thiolactone by gas chromatogra-phy/mass spectrometry. Rapid Commun Mass Sp 17: 358-362.
-
(2003)
Rapid Commun Mass Sp
, vol.17
, pp. 358-362
-
-
Daneshvar, P.1
Yazdanpanah, M.2
Cuthbert, C.3
Cole, D.E.4
-
28
-
-
3242746092
-
Cerebral vascular dysfunction mediated by super-oxide in hyperhomocysteinemic mice
-
Dayal S, Arning E, Bottiglieri T, Boger RH, Sigmund CD, Faraci FM, Lentz SR (2004) Cerebral vascular dysfunction mediated by super-oxide in hyperhomocysteinemic mice. Stroke 35: 1957-1962.
-
(2004)
Stroke
, vol.35
, pp. 1957-1962
-
-
Dayal, S.1
Arning, E.2
Bottiglieri, T.3
Boger, R.H.4
Sigmund, C.D.5
Faraci, F.M.6
Lentz, S.R.7
-
29
-
-
0036890065
-
Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease
-
De Bree A, Verschuren WMM, Kromhout D, Kluijtmans LAJ, Blom HJ (2002) Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease. Pharmacol Rev 54: 599-618.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 599-618
-
-
De Bree, A.1
Verschuren, W.M.M.2
Kromhout, D.3
Kluijtmans, L.A.J.4
Blom, H.J.5
-
30
-
-
0033996557
-
Evaluation of the Abbott Imx™ fluorescence polarization immunoassay and the Bio-Rad enzyme immunoassay for homocysteine: Comparison with high-performance liquid chromatography
-
Donnelly JG, Pronovost C (2000) Evaluation of the Abbott Imx™ fluorescence polarization immunoassay and the Bio-Rad enzyme immunoassay for homocysteine: comparison with high-performance liquid chromatography. Ann Clin Biochem 37: 194-198.
-
(2000)
Ann Clin Biochem
, vol.37
, pp. 194-198
-
-
Donnelly, J.G.1
Pronovost, C.2
-
31
-
-
38949198356
-
Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats
-
Edirimanne VER, Woo CWH, Siow YL, Pierce GN, Xie JY (2007) Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats. Can J Physiol Pharm 85: 1236-1247.
-
(2007)
Can J Physiol Pharm
, vol.85
, pp. 1236-1247
-
-
Edirimanne, V.E.R.1
Woo, C.W.H.2
Siow, Y.L.3
Pierce, G.N.4
Xie, J.Y.5
-
32
-
-
0034056466
-
Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke
-
Eikelboom JW, Hankey GJ, Anand SS, Lofthouse E, Staples N, Baker RI (2000) Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke. Stroke 31: 1069-1075.
-
(2000)
Stroke
, vol.31
, pp. 1069-1075
-
-
Eikelboom, J.W.1
Hankey, G.J.2
Anand, S.S.3
Lofthouse, E.4
Staples, N.5
Baker, R.I.6
-
33
-
-
0037145859
-
Homocysteine promotes the LDL oxidase activity of ceruloplasmin
-
Exner M, Hermann M, Hofbauer R, Hartmann B, Kapiotis S, Gmeiner B (2002) Homocysteine promotes the LDL oxidase activity of ceruloplasmin. FEBS Lett 531: 402-406.
-
(2002)
FEBS Lett
, vol.531
, pp. 402-406
-
-
Exner, M.1
Hermann, M.2
Hofbauer, R.3
Hartmann, B.4
Kapiotis, S.5
Gmeiner, B.6
-
34
-
-
0034575668
-
Total plasma homocysteine analysis by HPLC with SBD-F precolumn derivatization
-
Cooper C, Packer N, Williams K, eds, Humana Press Inc., Totova, NJ
-
Fermo I, Paroni R (2000) Total plasma homocysteine analysis by HPLC with SBD-F precolumn derivatization. In Amino Acid Analysis Protocols, Series: Methods in Molecular Biology Vol No 159. Cooper C, Packer N, Williams K, eds, pp 237-244. Humana Press Inc., To-tova, NJ.
-
(2000)
Amino Acid Analysis Protocols, Series: Methods in Molecular Biology
, vol.159
, pp. 237-244
-
-
Fermo, I.1
Paroni, R.2
-
35
-
-
0031748093
-
The metabolism of homocysteine: Pathways and regulation
-
Finkelstein JD (1998) The metabolism of homocysteine: pathways and regulation. Eur J Pediatr 157: S40-Z44.
-
(1998)
Eur J Pediatr
, vol.157
-
-
Finkelstein, J.D.1
-
36
-
-
0031886747
-
Enzyme conversion immunoassay for determining total homocysteine in plasma or serum
-
Frantzen F, Faaren AL, Alfheim I, Nordhei AK (1998) Enzyme conversion immunoassay for determining total homocysteine in plasma or serum. Clin Chem 44: 311-316.
-
(1998)
Clin Chem
, vol.44
, pp. 311-316
-
-
Frantzen, F.1
Faaren, A.L.2
Alfheim, I.3
Nordhei, A.K.4
-
37
-
-
48949084887
-
Increased homocysteine-induced release of excitatory amino acids in the striatum of spontaneously hypertensine stroke-prone rats
-
Ganguly PK, Maddaford TG, Edel AL, O K, Smeda JS, Pierce GN (2008) Increased homocysteine-induced release of excitatory amino acids in the striatum of spontaneously hypertensine stroke-prone rats. Brain Res 1226: 192-198.
-
(2008)
Brain Res
, vol.1226
, pp. 192-198
-
-
Ganguly, P.K.1
Maddaford, T.G.2
Edel, A.L.O.K.3
Smeda, J.S.4
Pierce, G.N.5
-
38
-
-
70249128338
-
Fully automated method for simultaneous determination of total cysteine, cysteinylglycine, glutathione and homocysteine in plasma by HPLC with UV absorbance detection
-
Glowacki R, Bald E (2009) Fully automated method for simultaneous determination of total cysteine, cysteinylglycine, glutathione and homocysteine in plasma by HPLC with UV absorbance detection. J Chromatogr B Analyt Technol Biomed Life Sci 877: 3400-3404.
-
(2009)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.877
, pp. 3400-3404
-
-
Glowacki, R.1
Bald, E.2
-
39
-
-
31344478190
-
Homocysteine from endothelial cells promotes LDL nitration and scavenger receptor uptake
-
Griffiths HR, Alfred S, Dale C, Nakano E, Kitas GD, Grant MG, Nuget D, Taiwo FA, Li L, Powers HJ (2006) Homocysteine from endothelial cells promotes LDL nitration and scavenger receptor uptake. Free Radical Biol Med 40: 488-500.
-
(2006)
Free Radical Biol Med
, vol.40
, pp. 488-500
-
-
Griffiths, H.R.1
Alfred, S.2
Dale, C.3
Nakano, E.4
Kitas, G.D.5
Grant, M.G.6
Nuget, D.7
Taiwo, F.A.8
Li, L.9
Powers, H.J.10
-
40
-
-
4644355552
-
Variation in plasma cystathionine and its relation to changes in plasma concentrations of homocysteine and methionine in healthy subjects during a 24-h observation period
-
Guttormsen AB, Solheim E, Refsum H (2004) Variation in plasma cystathionine and its relation to changes in plasma concentrations of homocysteine and methionine in healthy subjects during a 24-h observation period. Am J Clin Nutr 79: 76-79.
-
(2004)
Am J Clin Nutr
, vol.79
, pp. 76-79
-
-
Guttormsen, A.B.1
Solheim, E.2
Refsum, H.3
-
41
-
-
0032540276
-
Tissue plasminogen activator binding to the annexin II tail domain. Direct moduation by homocysteine
-
Hajjar KA, Mauri L, Jacovina AT, Zhong F, Mirza UA, Padovan JC, Chait B (1998) Tissue plasminogen activator binding to the annexin II tail domain. Direct moduation by homocysteine. J Biol Chem 273: 9987-9993.
-
(1998)
J Biol Chem
, vol.273
, pp. 9987-9993
-
-
Hajjar, K.A.1
Mauri, L.2
Jacovina, A.T.3
Zhong, F.4
Mirza, U.A.5
Padovan, J.C.6
Chait, B.7
-
42
-
-
34548017218
-
Extended storage of whole blood with 3-deazaadenosine for homocysteine assay
-
Hansrani M, Stansby G (2007) Extended storage of whole blood with 3-deazaadenosine for homocysteine assay. Ann Clin Biochem 44: 388-390.
-
(2007)
Ann Clin Biochem
, vol.44
, pp. 388-390
-
-
Hansrani, M.1
Stansby, G.2
-
43
-
-
64849100782
-
Characterization of cysteine and homocysteine bound to human serum transthyretin
-
Hanyu N, Shimizu T, Yamauchi K, Okumura N, Hidaka H (2009) Characterization of cysteine and homocysteine bound to human serum transthyretin. Clin Chim Acta 403: 70-75.
-
(2009)
Clin Chim Acta
, vol.403
, pp. 70-75
-
-
Hanyu, N.1
Shimizu, T.2
Yamauchi, K.3
Okumura, N.4
Hidaka, H.5
-
44
-
-
0036892748
-
Multiple aspects of homocysteine neurotoxicity: Glutamate excitotoxicity, kinase hyperactivation and DNA damage
-
Ho PI, Ortiz D, Rogers E, Shea TB (2002) Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage. J Neurosci Res 70: 694-702.
-
(2002)
J Neurosci Res
, vol.70
, pp. 694-702
-
-
Ho, P.I.1
Ortiz, D.2
Rogers, E.3
Shea, T.B.4
-
45
-
-
0035107609
-
Hyper-homocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
-
Hofmann MA, Lalla E, Gleason MR, Wolf BM, Tanji N, Ferran LJ, Kohl B, Rap V, Kisiel W, Stern DM, Schmidt AM (2001) Hyper-homocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model. J Clin Invest 107: 675-683.
-
(2001)
J Clin Invest
, vol.107
, pp. 675-683
-
-
Hofmann, M.A.1
Lalla, E.2
Gleason, M.R.3
Wolf, B.M.4
Tanji, N.5
Ferran, L.J.6
Kohl, B.7
Rap, V.8
Kisiel, W.9
Stern, D.M.10
Schmidt, A.M.11
-
46
-
-
36849001753
-
Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-l-homocysteine and hydrogen peroxide: Analysis, quantification, and implications for hyperhomo-cysteinemia
-
Hong I, Fast W (2007) Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-l-homocysteine and hydrogen peroxide: analysis, quantification, and implications for hyperhomo-cysteinemia. J Biol Chem 282: 34684-34692.
-
(2007)
J Biol Chem
, vol.282
, pp. 34684-34692
-
-
Hong, I.1
Fast, W.2
-
47
-
-
33845533655
-
Bound homocysteine, cysteine, and cysteinylglycine distribution between albumin and globulins
-
Hortin GL, Seam N, Hoehn GT (2006) Bound homocysteine, cysteine, and cysteinylglycine distribution between albumin and globulins. Clin Chem 52: 2258-2264.
-
(2006)
Clin Chem
, vol.52
, pp. 2258-2264
-
-
Hortin, G.L.1
Seam, N.2
Hoehn, G.T.3
-
48
-
-
0035021823
-
Simultaneous determination of total plasma glutathione, homo-cysteine, cysteinylglycine, and methionine by high-performance liquid chromatography with electrochemical detection
-
Houze P, Gamra S, Madelaine I, Bousquet B, Gourmel B (2006) Simultaneous determination of total plasma glutathione, homo-cysteine, cysteinylglycine, and methionine by high-performance liquid chromatography with electrochemical detection. J Clin Lab Anal 15: 144-153.
-
(2006)
J Clin Lab Anal
, vol.15
, pp. 144-153
-
-
Houze, P.1
Gamra, S.2
Madelaine, I.3
Bousquet, B.4
Gourmel, B.5
-
49
-
-
64949116621
-
A highly selective phosphorescent chemodosimeter for cysteine and homocysteine based on platinum (II) complexs
-
Huang K, Yang H, Zhou Z, Chen H, Li F, Yi T, Huang C (2009) A highly selective phosphorescent chemodosimeter for cysteine and homocysteine based on platinum (II) complexs. Inorg Chim Acta 362: 2577-2580.
-
(2009)
Inorg Chim Acta
, vol.362
, pp. 2577-2580
-
-
Huang, K.1
Yang, H.2
Zhou, Z.3
Chen, H.4
Li, F.5
Yi, T.6
Huang, C.7
-
50
-
-
4344683549
-
Homo-cysteine induced impairement of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL
-
Hucks D, Thuraisingham RC, Raftery MJ, Yagoob MM (2004) Homo-cysteine induced impairement of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL. Nephrol Dial Transpl 19: 1999-2005.
-
(2004)
Nephrol Dial Transpl
, vol.19
, pp. 1999-2005
-
-
Hucks, D.1
Thuraisingham, R.C.2
Raftery, M.J.3
Yagoob, M.M.4
-
51
-
-
38349181044
-
Homocysteine stimulates monocyte chemoattractant protein-1 expression in the kidney via nuclear factor-κB activation
-
Hwang S-Y, Woo CWH, Au-Yeung KKW, Siow YL, Zhu TY, Karmin O (2008) Homocysteine stimulates monocyte chemoattractant protein-1 expression in the kidney via nuclear factor-κB activation. Am J Physiol-Renal 294: F236-244.
-
(2008)
Am J Physiol-Renal
, vol.294
-
-
Hwang, S.-Y.1
Woo, C.W.H.2
Au-Yeung, K.K.W.3
Siow, Y.L.4
Zhu, T.Y.5
Karmin, O.6
-
52
-
-
70349480989
-
A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasma
-
Ichinose S, Nakamura M, Maeda M, Ikeda R, Wada M, Nakazato M, Ohba Y, Takamura N, Maeda T, Aoyagi K, Nakashima K (2009) A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasma. Biomed Chromatogr 23: 935-939.
-
(2009)
Biomed Chromatogr
, vol.23
, pp. 935-939
-
-
Ichinose, S.1
Nakamura, M.2
Maeda, M.3
Ikeda, R.4
Wada, M.5
Nakazato, M.6
Ohba, Y.7
Takamura, N.8
Maeda, T.9
Aoyagi, K.10
Nakashima, K.11
-
53
-
-
0034022607
-
Hyperhomocysteinemia and oxidative stress: Time for a reality check?
-
Jacobsen DW (2000) Hyperhomocysteinemia and oxidative stress: time for a reality check? Arterioscl Throm Vas 20: 1182-1184.
-
(2000)
Arterioscl Throm Vas
, vol.20
, pp. 1182-1184
-
-
Jacobsen, D.W.1
-
54
-
-
0001640331
-
Limited capacity for homocysteine catabolism in vascular cells and tissues: A pathophysiologic mechanism for arterial damage in hyperhomocysteinemia?
-
Jacobsen DW, Savon SR, Stewart RW, Robinson K, Kottke-Marchant K, Di Corleto PE (1995) Limited capacity for homocysteine catabolism in vascular cells and tissues: a pathophysiologic mechanism for arterial damage in hyperhomocysteinemia? Circulation 91: 29-33.
-
(1995)
Circulation
, vol.91
, pp. 29-33
-
-
Jacobsen, D.W.1
Savon, S.R.2
Stewart, R.W.3
Robinson, K.4
Kottke-Marchant, K.5
Di Corleto, P.E.6
-
55
-
-
0031035742
-
Metabolism of homocysteine thiolactone in human cell cultures. Possible mechanism for pathological consequences of elevated homocysteine levels
-
Jakubowski H (1997) Metabolism of homocysteine thiolactone in human cell cultures. Possible mechanism for pathological consequences of elevated homocysteine levels. J Biol Chem 272: 1935-1942.
-
(1997)
J Biol Chem
, vol.272
, pp. 1935-1942
-
-
Jakubowski, H.1
-
56
-
-
0032778517
-
Protein homocysteinylation: Possible mechanism underlying pathological consequences of elevated homocysteine levels
-
Jakubowski H (1999) Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels. FASEB J 13: 2277-2283.
-
(1999)
FASEB J
, vol.13
, pp. 2277-2283
-
-
Jakubowski, H.1
-
57
-
-
0034635449
-
Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation
-
Jakubowski H (2000) Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation. J Biol Chem 275: 3957-3962.
-
(2000)
J Biol Chem
, vol.275
, pp. 3957-3962
-
-
Jakubowski, H.1
-
58
-
-
0037163003
-
Homocysteine is a protein amino acid in humans. Implications for homocysteine-linked disease
-
Jakubowski H (2002a) Homocysteine is a protein amino acid in humans. Implications for homocysteine-linked disease. J Biol Chem 277: 30425-30428.
-
(2002)
J Biol Chem
, vol.277
, pp. 30425-30428
-
-
Jakubowski, H.1
-
59
-
-
0036750807
-
The determination of homocysteine-thiolactone in biological samples
-
Jakubowski H (2002b) The determination of homocysteine-thiolactone in biological samples. Anal Biochem 308: 112-119.
-
(2002)
Anal Biochem
, vol.308
, pp. 112-119
-
-
Jakubowski, H.1
-
60
-
-
33646788784
-
Pathophysiological consequences of homo-cysteine excess
-
Jakubowski H (2006) Pathophysiological consequences of homo-cysteine excess. J Nutr 136: 1741S-1749S.
-
(2006)
J Nutr
, vol.136
-
-
Jakubowski, H.1
-
61
-
-
64049095638
-
The pathophysiological hypothesis of homo-cysteine thiolactone-mediated vascular disease
-
Jakubowski H (2008a) The pathophysiological hypothesis of homo-cysteine thiolactone-mediated vascular disease. J Physiol Pharmacol 59: 155-167.
-
(2008)
J Physiol Pharmacol
, vol.59
, pp. 155-167
-
-
Jakubowski, H.1
-
62
-
-
47749089308
-
New method for the determination of protein N-linked homocysteine
-
Jakubowski H (2008b) New method for the determination of protein N-linked homocysteine. Anal Biochem 380: 257-261.
-
(2008)
Anal Biochem
, vol.380
, pp. 257-261
-
-
Jakubowski, H.1
-
63
-
-
57349180605
-
Mutations in cystath-ionine beta-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans
-
Jakubowski H, Boers GHJ, Strauss KA (2008) Mutations in cystath-ionine beta-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans. FASEB J 22: 4071-4076.
-
(2008)
FASEB J
, vol.22
, pp. 4071-4076
-
-
Jakubowski, H.1
Boers, G.H.J.2
Strauss, K.A.3
-
64
-
-
67649371083
-
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice
-
Jakubowski H, Perla-Kajan J, Finnell RH, Cabrera RM, Wang H, Gupta S, Kruger WD, Kraus JP, Shih DM (2009) Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB J 23: 1721-1727.
-
(2009)
FASEB J
, vol.23
, pp. 1721-1727
-
-
Jakubowski, H.1
Perla-Kajan, J.2
Finnell, R.H.3
Cabrera, R.M.4
Wang, H.5
Gupta, S.6
Kruger, W.D.7
Kraus, J.P.8
Shih, D.M.9
-
65
-
-
36348971786
-
Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene
-
Jamaluddin MS, Chen I, Yang F, Jiang X, Jan M, Liu X, Schafer AI, Durante W, Yang X, Wang H (2007) Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. Blood 110: 3648-3455.
-
(2007)
Blood
, vol.110
, pp. 3648-3455
-
-
Jamaluddin, M.S.1
Chen, I.2
Yang, F.3
Jiang, X.4
Jan, M.5
Liu, X.6
Schafer, A.I.7
Durante, W.8
Yang, X.9
Wang, H.10
-
66
-
-
4644257043
-
Homocysteine: It is a clinically important cardiovascular risk factor?
-
Lentz SR, Haynes WG (2004) Homocysteine: It is a clinically important cardiovascular risk factor? Clev Clin J Med 71: 729-734.
-
(2004)
Clev Clin J Med
, vol.71
, pp. 729-734
-
-
Lentz, S.R.1
Haynes, W.G.2
-
67
-
-
30744450012
-
Elevated levels of homocysteine compromise blood-brain barrier integrity in mice
-
Kamath AF, Chauhan AK, Kisucka J, Dole VS, Loscalzo J, Handy DE, Wagner DD (2006) Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. Blood 107: 591-593.
-
(2006)
Blood
, vol.107
, pp. 591-593
-
-
Kamath, A.F.1
Chauhan, A.K.2
Kisucka, J.3
Dole, V.S.4
Loscalzo, J.5
Handy, D.E.6
Wagner, D.D.7
-
68
-
-
0028910633
-
Determination of total plasma homocysteine and related aminothiols by gas chromatography with flame photometric detection
-
Kataoka H, Takagi K, Makita M (1995) Determination of total plasma homocysteine and related aminothiols by gas chromatography with flame photometric detection. J Chromatogr B Biomed Appl 664: 421-425.
-
(1995)
J Chromatogr B Biomed Appl
, vol.664
, pp. 421-425
-
-
Kataoka, H.1
Takagi, K.2
Makita, M.3
-
69
-
-
67349235526
-
Association of homocysteine thiolactonase activity and PON1 polymorphism with the severity of acute coronary syndrome
-
Koubaa N, Nakbi A, Hammami S, Attia N, Mehri S, Ben Hamda K, Ben Farhat M, Miled A, Hammami M (2009) Association of homocysteine thiolactonase activity and PON1 polymorphism with the severity of acute coronary syndrome. Clin Biochem 42: 771-776.
-
(2009)
Clin Biochem
, vol.42
, pp. 771-776
-
-
Koubaa, N.1
Nakbi, A.2
Hammami, S.3
Attia, N.4
Mehri, S.5
Ben Hamda, K.6
Ben Farhat, M.7
Miled, A.8
Hammami, M.9
-
70
-
-
0034666267
-
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
-
Kruman II, Culmsee C, Chan SL, Kruman Y, Guo Z, Penix L, Mattson MP (2000) Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity. J Neurosci 20: 6920-6926.
-
(2000)
J Neurosci
, vol.20
, pp. 6920-6926
-
-
Kruman, I.I.1
Culmsee, C.2
Chan, S.L.3
Kruman, Y.4
Guo, Z.5
Penix, L.6
Mattson, M.P.7
-
71
-
-
32844469944
-
Rapid micro-scale assay for homocysteine by liquid chromatography-tandem mass spectrometry
-
Kuhn J, Gotting C, Kleesiek K (2006) Rapid micro-scale assay for homocysteine by liquid chromatography-tandem mass spectrometry. Clin Biochem 39: 164-166.
-
(2006)
Clin Biochem
, vol.39
, pp. 164-166
-
-
Kuhn, J.1
Gotting, C.2
Kleesiek, K.3
-
72
-
-
77953133802
-
Efficacy of homo-cysteine-lowering therapy with folic acid in stroke prevention
-
Lee M, Hong K-S, Chang S-C, Saver JL (2010) Efficacy of homo-cysteine-lowering therapy with folic acid in stroke prevention. Stroke 41: 1205-1212.
-
(2010)
Stroke
, vol.41
, pp. 1205-1212
-
-
Lee, M.1
Hong, K.-S.2
Chang, S.-C.3
Saver, J.L.4
-
73
-
-
0042919553
-
Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: A multicenter case-control study in china
-
Li Z, Sun L, Zhang H, Liao Y, Wang D, Zhao B, Zhu Z, Zhao J, Ma A, Han Y, Wang Y, Shi Y, Ye J, Hui R (2003) Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a multicenter case-control study in china. Stroke 34: 2085-2090.
-
(2003)
Stroke
, vol.34
, pp. 2085-2090
-
-
Li, Z.1
Sun, L.2
Zhang, H.3
Liao, Y.4
Wang, D.5
Zhao, B.6
Zhu, Z.7
Zhao, J.8
Ma, A.9
Han, Y.10
Wang, Y.11
Shi, Y.12
Ye, J.13
Hui, R.14
-
74
-
-
0028907918
-
Plasma homocysteine in the acute and convalescent phase after stroke
-
Lindgren A, Brattstrom L, Norrving B, Hultberg B, Andersson A, Johansson BB (1995) Plasma homocysteine in the acute and convalescent phase after stroke. Stroke 26: 795-800.
-
(1995)
Stroke
, vol.26
, pp. 795-800
-
-
Lindgren, A.1
Brattstrom, L.2
Norrving, B.3
Hultberg, B.4
Andersson, A.5
Johansson, B.B.6
-
75
-
-
0031437426
-
Irreversible inhibition of lysyl oxidase by homocysteine thiolactone and its selenium and oxygen analogues. Implications for homocystinuria
-
Liu G, Nellaiappan K, Kagan H (1997) Irreversible inhibition of lysyl oxidase by homocysteine thiolactone and its selenium and oxygen analogues. Implications for homocystinuria. J Biol Chem 272: 32370-32377.
-
(1997)
J Biol Chem
, vol.272
, pp. 32370-32377
-
-
Liu, G.1
Nellaiappan, K.2
Kagan, H.3
-
77
-
-
0036341545
-
Homocysteine binds to human plasma fibronectin and inhibits its interaction with fibrin
-
Majors AK, Sengupta S, Willard B, Kinter MT, Pyeritz RE, Jacobsen DW (2002) Homocysteine binds to human plasma fibronectin and inhibits its interaction with fibrin. Arterioscl Throm Vas 22: 1354- 1359.
-
(2002)
Arterioscl Throm Vas
, vol.22
, pp. 1354-1359
-
-
Majors, A.K.1
Sengupta, S.2
Willard, B.3
Kinter, M.T.4
Pyeritz, R.E.5
Jacobsen, D.W.6
-
78
-
-
43349106781
-
Homocysteine measurement by Vitros Microtip homo-cysteine assay
-
Martens GA, De Nayer J, De Smet D, Couck P, Gorus F, Gerlo E (2008) Homocysteine measurement by Vitros Microtip homo-cysteine assay. Clin Chem Lab Med 46: 283-286.
-
(2008)
Clin Chem Lab Med
, vol.46
, pp. 283-286
-
-
Martens, G.A.1
De Nayer, J.2
De Smet, D.3
Couck, P.4
Gorus, F.5
Gerlo, E.6
-
79
-
-
0033050869
-
Plasma total homocysteine measurement by ion-paired reversed-phase HPLC with electrochemical detection
-
Martin SC, Hilton AC, Bartlett WA, Jones AF (1999) Plasma total homocysteine measurement by ion-paired reversed-phase HPLC with electrochemical detection. Biomed Chromatogr 13: 81-82.
-
(1999)
Biomed Chromatogr
, vol.13
, pp. 81-82
-
-
Martin, S.C.1
Hilton, A.C.2
Bartlett, W.A.3
Jones, A.F.4
-
80
-
-
0037364417
-
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders
-
Mattson MP, Shea TB (2003) Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders. Trends Neurosci 26: 137-146.
-
(2003)
Trends Neurosci
, vol.26
, pp. 137-146
-
-
Mattson, M.P.1
Shea, T.B.2
-
81
-
-
33645457949
-
Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway
-
Moshal KS, Sen U, Tyagi N, Henderson B, Steed M, Ovechkin AV, Tyagi SC (2006) Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway. Am J Physiol-Cell Ph 290: C883-891.
-
(2006)
Am J Physiol-Cell Ph
, vol.290
-
-
Moshal, K.S.1
Sen, U.2
Tyagi, N.3
Henderson, B.4
Steed, M.5
Ovechkin, A.V.6
Tyagi, S.C.7
-
82
-
-
0036165216
-
Determination of homocysteine thiolactone and homocysteine in cell cultures using high-performance liquid chromatography with fluorescence detection
-
Mukai Y, Togawa T, Suzuki T, Ohata K, Tanabe S (2002) Determination of homocysteine thiolactone and homocysteine in cell cultures using high-performance liquid chromatography with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci 767: 263-268.
-
(2002)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.767
, pp. 263-268
-
-
Mukai, Y.1
Togawa, T.2
Suzuki, T.3
Ohata, K.4
Tanabe, S.5
-
83
-
-
1842370239
-
Plasma homocysteine levels and mortality in patients with coronary artery disease
-
Nygard O, Nordrehaug JE, Refsum H, Ueland PM, Farstad M, Voll-set SE (1997) Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 337: 230-237.
-
(1997)
N Engl J Med
, vol.337
, pp. 230-237
-
-
Nygard, O.1
Nordrehaug, J.E.2
Refsum, H.3
Ueland, P.M.4
Farstad, M.5
Vollset, S.E.6
-
84
-
-
0345535616
-
Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells
-
Outinen PA, Sood SK, Pfeifer SI, Pamidi S, Podor TJ, Li J, Weitz JI, Austin R (1999) Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells. Blood 94: 959-967.
-
(1999)
Blood
, vol.94
, pp. 959-967
-
-
Outinen, P.A.1
Sood, S.K.2
Pfeifer, S.I.3
Pamidi, S.4
Podor, T.J.5
Li, J.6
Weitz, J.I.7
Austin, R.8
-
85
-
-
0036468241
-
Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate
-
Patel KB, Stratford MR, Wardman P, Everett SA (2002) Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate. Free Radical Biol Med 32: 203- 211.
-
(2002)
Free Radical Biol Med
, vol.32
-
-
Patel, K.B.1
Stratford, M.R.2
Wardman, P.3
Everett, S.A.4
-
86
-
-
30744464594
-
Elevated plasma homocysteine in acute stroke was not associated with severity and outcome: Stronger association with small artery disease
-
Perini F, Galloni E, Bolgan I, Bader G, Ruffini R, Arzenton E, Alba S, Azzini C, Bartolomei L, Billo G, Bortolon F, Dudine P, Garofalo PG, L'Erario R, Morra M, Parisen P, Stenta G, Toso V (2005) Elevated plasma homocysteine in acute stroke was not associated with severity and outcome: stronger association with small artery disease. Neurol Sci 26: 310-318.
-
(2005)
Neurol Sci
, vol.26
, pp. 310-318
-
-
Perini, F.1
Galloni, E.2
Bolgan, I.3
Bader, G.4
Ruffini, R.5
Arzenton, E.6
Alba, S.7
Azzini, C.8
Bartolomei, L.9
Billo, G.10
Bortolon, F.11
Dudine, P.12
Garofalo, P.G.13
L'Erario, R.14
Morra, M.15
Parisen, P.16
Stenta, G.17
Toso, V.18
-
87
-
-
77952294286
-
Paraoxonase 1 protects against protein N-homocysteinylation in humans
-
Perla-Kajan J, Jakubowski H (2010) Paraoxonase 1 protects against protein N-homocysteinylation in humans. FASEB J 24: 931-936.
-
(2010)
FASEB J
, vol.24
, pp. 931-936
-
-
Perla-Kajan, J.1
Jakubowski, H.2
-
88
-
-
33644504239
-
Increased plasma protein homocysteinylation in hemodialysis patients
-
Perna AF, Satta E, Acanfora F, Lombardi C, Ingrosso D, De Santo NG (2006) Increased plasma protein homocysteinylation in hemodialysis patients. Kidney Int 69: 869-876.
-
(2006)
Kidney Int
, vol.69
, pp. 869-876
-
-
Perna, A.F.1
Satta, E.2
Acanfora, F.3
Lombardi, C.4
Ingrosso, D.5
De Santo, N.G.6
-
89
-
-
0028845307
-
Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men
-
Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG (1995) Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 346: 1395- 1398.
-
(1995)
Lancet
, vol.346
-
-
Perry, I.J.1
Refsum, H.2
Morris, R.W.3
Ebrahim, S.B.4
Ueland, P.M.5
Shaper, A.G.6
-
90
-
-
33847176190
-
Homocysteine and cerebral ischemia: Pathogenic and therapeutical implications
-
Pezzini A, Del Zotto E, Padovani A (2007) Homocysteine and cerebral ischemia: pathogenic and therapeutical implications. Curr Med Chem 14: 249-263.
-
(2007)
Curr Med Chem
, vol.14
, pp. 249-263
-
-
Pezzini, A.1
Del Zotto, E.2
Padovani, A.3
-
91
-
-
0035810980
-
Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: Implications for vascular disease
-
Poddar R, Sivasubramanian N, DiBello PM, Robinson K, Jacobsen DW (2001) Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease. Circulation 103: 2717-2723.
-
(2001)
Circulation
, vol.103
, pp. 2717-2723
-
-
Poddar, R.1
Sivasubramanian, N.2
Dibello, P.M.3
Robinson, K.4
Jacobsen, D.W.5
-
92
-
-
67650484107
-
Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death
-
Poddar R, Paul S (2009) Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death. J Neurochem 110: 1095-1106.
-
(2009)
J Neurochem
, vol.110
, pp. 1095-1106
-
-
Poddar, R.1
Paul, S.2
-
93
-
-
34447259792
-
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: Summary of a symposium
-
Purohit V, Abdelmalek MF, Barve S, Benevenga NJ, Halsted CH, Kaplowitz N, Kharbanda KK, Liu Q-Y, Lu SC, McClain CJ, Swanson C, Zakhari S (2007) Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium. Am J Clin Nutr 86: 14-24.
-
(2007)
Am J Clin Nutr
, vol.86
, pp. 14-24
-
-
Purohit, V.1
Abdelmalek, M.F.2
Barve, S.3
Benevenga, N.J.4
Halsted, C.H.5
Kaplowitz, N.6
Kharbanda, K.K.7
Liu, Q.-Y.8
Lu, S.C.9
Mcclain, C.J.10
Swanson, C.11
Zakhari, S.12
-
94
-
-
5444220704
-
High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells
-
Raposo B, Rodriguez C, Martinez-Gonzalez J, Badimon L (2004) High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells. Atherosclerosis 177: 1-8.
-
(2004)
Atherosclerosis
, vol.177
, pp. 1-8
-
-
Raposo, B.1
Rodriguez, C.2
Martinez-Gonzalez, J.3
Badimon, L.4
-
95
-
-
67349267983
-
2+-ATPases in rats subjected to acute homocysteine and homocysteine thiolactone administration
-
2+-ATPases in rats subjected to acute homocysteine and homocysteine thiolactone administration. Mol Cell Biochem 327: 39-45.
-
(2009)
Mol Cell Biochem
, vol.327
, pp. 39-45
-
-
Rasic-Markovic, A.1
Stanojlovic, O.2
Hrncic, D.3
Krstic, D.4
Colovic, M.5
Susic, V.6
Radosavljevic, T.7
Djuric, D.8
-
96
-
-
0033822684
-
Total homocysteine determination in clinical practice
-
Rasmussen K, Moller J (2000) Total homocysteine determination in clinical practice. Ann Clin Biochem 37: 627-648.
-
(2000)
Ann Clin Biochem
, vol.37
, pp. 627-648
-
-
Rasmussen, K.1
Moller, J.2
-
97
-
-
9144225352
-
Facts and recommendations about total homocysteine determinations: An expert opinion
-
Refsum H, Smith AD, Ueland PM, Nexo E, Clarke R, McPartlin J, Johnston C, Engbaek F, Schneede J, McPartlin C, Scott JM (2004) Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 50: 3-32.
-
(2004)
Clin Chem
, vol.50
, pp. 3-32
-
-
Refsum, H.1
Smith, A.D.2
Ueland, P.M.3
Nexo, E.4
Clarke, R.5
Mcpartlin, J.6
Johnston, C.7
Engbaek, F.8
Schneede, J.9
Mcpartlin, C.10
Scott, J.M.11
-
98
-
-
2442472190
-
Performance characteristics of a recombinant enzymatic cycling assay for quantification of total homocysteine in serum or plasma
-
Roberts RF, Roberts WL (2004) Performance characteristics of a recombinant enzymatic cycling assay for quantification of total homocysteine in serum or plasma. Clin Chim Acta 344: 95-99.
-
(2004)
Clin Chim Acta
, vol.344
, pp. 95-99
-
-
Roberts, R.F.1
Roberts, W.L.2
-
99
-
-
0032758245
-
Stability of blood homocysteine and other thiols: EDTA or acidic citrate?
-
Salazar J-F, Herbeth B, Siest G, Leroy P (1999) Stability of blood homocysteine and other thiols: EDTA or acidic citrate? Clin Chem 45: 2016-2019.
-
(1999)
Clin Chem
, vol.45
, pp. 2016-2019
-
-
Salazar, J.-F.1
Herbeth, B.2
Siest, G.3
Leroy, P.4
-
100
-
-
65249094749
-
Homocysteine-lowering therapy and stroke risk, severity, and disability. Additional findings from the HOPE 2 Trial
-
Saposnik G, Ray JG, Sheridan P, McQueen M, Lonn E (2009) Homocysteine-lowering therapy and stroke risk, severity, and disability. Additional findings from the HOPE 2 Trial. Stroke 40: 1365-1372.
-
(2009)
Stroke
, vol.40
, pp. 1365-1372
-
-
Saposnik, G.1
Ray, J.G.2
Sheridan, P.3
Mcqueen, M.4
Lonn, E.5
-
101
-
-
41549111412
-
Improved HPLC method for total plasma homocysteine detection and quantification
-
Sawuła W, Banecka-Majkutewicz Z, Kadziński L, Jakóbkiewicz-Ba-necka J, We{ogonek}grzyn G, Nyka W, Banecki B (2008) Improved HPLC method for total plasma homocysteine detection and quantification. Acta Biochim Pol 55: 119-125.
-
(2008)
Acta Biochim Pol
, vol.55
, pp. 119-125
-
-
Sawuła, W.1
Banecka-Majkutewicz, Z.2
Kadziński, L.3
Jakóbkiewicz-Ba-necka, J.4
Wegrzyn, G.5
Nyka, W.6
Banecki, B.7
-
102
-
-
3042767565
-
Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons
-
Selley ML (2004) Homocysteine increases the production of asymmetric dimethylarginine in cultured neurons. J Neurosci Res 77: 90-93.
-
(2004)
J Neurosci Res
, vol.77
, pp. 90-93
-
-
Selley, M.L.1
-
103
-
-
27644521579
-
Vitamin intervention for stroke prevention trial: An efficacy analysis
-
Spence JD, Bang H, Chambless LE, Stampfer MJ (2005) Vitamin intervention for stroke prevention trial: an efficacy analysis. Stroke 36: 2404-2409.
-
(2005)
Stroke
, vol.36
, pp. 2404-2409
-
-
Spence, J.D.1
Bang, H.2
Chambless, L.E.3
Stampfer, M.J.4
-
104
-
-
56049120125
-
Methylenetetrahydrofolate reductase (MTHFR-677 and MTHFR-1298) genotypes and haplotypes and plasma homocysteine levels in patients with occlusive artery disease and deep venous thrombosis
-
Spiroski I, Kedev S, Antov S, Arsov T, Krstevska M, Dzhekova-Stojk-ova S, Bosilkova G, Kostovska S, Trajkov D, Petlichkovski A, Strezova A, Efinska-Mladenovska O, Spiroski M (2008) Methylenetet-rahydrofolate reductase (MTHFR-677 and MTHFR-1298) genotypes and haplotypes and plasma homocysteine levels in patients with occlusive artery disease and deep venous thrombosis. Acta Biochim Pol 55: 587-594.
-
(2008)
Acta Biochim Pol
, vol.55
, pp. 587-594
-
-
Spiroski, I.1
Kedev, S.2
Antov, S.3
Arsov, T.4
Krstevska, M.5
Dzhekova-Stojkova, S.6
Bosilkova, G.7
Kostovska, S.8
Trajkov, D.9
Petlichkovski, A.10
Strezova, A.11
Efinska-Mladenovska, O.12
Spiroski, M.13
-
105
-
-
3142729014
-
Sulfur amino acid metabolism: Pathways for production and removal of homocysteine and cysteine
-
Stipanuk MH (2004) Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine. Annu Rev Nutr 24: 539-577.
-
(2004)
Annu Rev Nutr
, vol.24
, pp. 539-577
-
-
Stipanuk, M.H.1
-
106
-
-
0031239784
-
Betain-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene
-
Sunden SL, Renduchintala MS, Park EI, Miklasz SD, Garrow TA (1997) Betain-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene. Arch Biochem Biophys 345: 171-174.
-
(1997)
Arch Biochem Biophys
, vol.345
, pp. 171-174
-
-
Sunden, S.L.1
Renduchintala, M.S.2
Park, E.I.3
Miklasz, S.D.4
Garrow, T.A.5
-
107
-
-
0022999801
-
Determination of in vivo protein binding of homocysteine and its relation to free homocysteine in the liver and other tissues of the rat
-
Syardal A, Refsum H, Ueland PM (1986) Determination of in vivo protein binding of homocysteine and its relation to free homocysteine in the liver and other tissues of the rat. J Biol Chem 261: 3156-3163.
-
(1986)
J Biol Chem
, vol.261
, pp. 3156-3163
-
-
Syardal, A.1
Refsum, H.2
Ueland, P.M.3
-
108
-
-
51649102863
-
A highly sensitive single-enzyme homocysteine assay
-
Tan Y, Hoffman RM (2008) A highly sensitive single-enzyme homocysteine assay. Nat Protoc 3: 1388-1394.
-
(2008)
Nat Protoc
, vol.3
, pp. 1388-1394
-
-
Tan, Y.1
Hoffman, R.M.2
-
109
-
-
40949149821
-
Dietary homocysteine promotes atherosclerosis in apoE-deficient mice by inducing scavenger receptors expression
-
Thampi P, Stewart BW, Joseph L, Melnyk SB, Hennings LJ, Nagarajan S (2008) Dietary homocysteine promotes atherosclerosis in apoE-deficient mice by inducing scavenger receptors expression. Atherosclerosis 197: 620-629.
-
(2008)
Atherosclerosis
, vol.197
, pp. 620-629
-
-
Thampi, P.1
Stewart, B.W.2
Joseph, L.3
Melnyk, S.B.4
Hennings, L.J.5
Nagarajan, S.6
-
110
-
-
1342309318
-
Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The vitamin intervention for stroke prevention (VISP) randomized controlled trial
-
Toole JF, Malinow MR, Chambless LE, Spence JD, Pettigrew LC, Howard VJ, Sides EG, Wang C-H, Stampfer M (2004) Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the vitamin intervention for stroke prevention (VISP) randomized controlled trial. JAMA 291: 565-575.
-
(2004)
JAMA
, vol.291
, pp. 565-575
-
-
Toole, J.F.1
Malinow, M.R.2
Chambless, L.E.3
Spence, J.D.4
Pettigrew, L.C.5
Howard, V.J.6
Sides, E.G.7
Wang, C.-H.8
Stampfer, M.9
-
112
-
-
65549159487
-
Activation of GABA-A receptor ameliorates homocysteine-induced MMP-9 activation by ERK pathway
-
Tyagi N, Gillespie W, Vacek JC, Sen U, Tyagi SC, Lominadze D (2009) Activation of GABA-A receptor ameliorates homocysteine-induced MMP-9 activation by ERK pathway. J Cell Physiol 220: 257-266.
-
(2009)
J Cell Physiol
, vol.220
, pp. 257-266
-
-
Tyagi, N.1
Gillespie, W.2
Vacek, J.C.3
Sen, U.4
Tyagi, S.C.5
Lominadze, D.6
-
113
-
-
23244456667
-
Homocysteine in micro-vascular endothelial cell barrier permeability
-
Tyagi SC, Lominadze D, Roberts AM (2005) Homocysteine in micro-vascular endothelial cell barrier permeability. Cell Biochem Biophys 43: 37-44.
-
(2005)
Cell Biochem Biophys
, vol.43
, pp. 37-44
-
-
Tyagi, S.C.1
Lominadze, D.2
Roberts, A.M.3
-
114
-
-
37549056545
-
Gamma-ami-nobutiric acid A receptor mitigates homocysteine-induced endothe-lial cell permeability
-
Tyagi N, Moshal KS, Tyagi SC, Lominadze D (2007) Gamma-ami-nobutiric acid A receptor mitigates homocysteine-induced endothe-lial cell permeability. Endothelium 14: 315-323.
-
(2007)
Endothelium
, vol.14
, pp. 315-323
-
-
Tyagi, N.1
Moshal, K.S.2
Tyagi, S.C.3
Lominadze, D.4
-
115
-
-
0033822337
-
Assay methods for the measurement of total homocyst(e)ine in plasma
-
Ubbink JB (2000) Assay methods for the measurement of total homocyst(e)ine in plasma. Semin Thromb Hemost 26: 233-241.
-
(2000)
Semin Thromb Hemost
, vol.26
, pp. 233-241
-
-
Ubbink, J.B.1
-
116
-
-
0036270587
-
Protein-bound homocystamide measured in human plasma by HPLC
-
Uji Y, Motomiva Y, Hanyu N, Ukaji F, Okabe H (2002) Protein-bound homocystamide measured in human plasma by HPLC. Clin Chem 48: 941-944.
-
(2002)
Clin Chem
, vol.48
, pp. 941-944
-
-
Uji, Y.1
Motomiva, Y.2
Hanyu, N.3
Ukaji, F.4
Okabe, H.5
-
117
-
-
2542618547
-
Autoantibodies against N-homocysteinylated proteins in humans: Implications for atherosclerosis
-
Undas A, Perla J, Lacinski M, Trzeciak W, Kazmierski R, Jakubowski H (2004) Autoantibodies against N-homocysteinylated proteins in humans: implications for atherosclerosis. Stroke 35: 1299-1304.
-
(2004)
Stroke
, vol.35
, pp. 1299-1304
-
-
Undas, A.1
Perla, J.2
Lacinski, M.3
Trzeciak, W.4
Kazmierski, R.5
Jakubowski, H.6
-
118
-
-
34347224500
-
Autoantibodies against N-homocysteinylated proteins in patients on long-term haemodialysis
-
Undas A, Kolarz M, Kopec G, Glowacki R, Placzkiewicz-Jankowska E, Tracz W (2007) Autoantibodies against N-homocysteinylated proteins in patients on long-term haemodialysis. Nephrol Dial Transpl 22: 1685-1689.
-
(2007)
Nephrol Dial Transpl
, vol.22
, pp. 1685-1689
-
-
Undas, A.1
Kolarz, M.2
Kopec, G.3
Glowacki, R.4
Placzkiewicz-Jankowska, E.5
Tracz, W.6
-
120
-
-
0036464601
-
Cyclin A transcriptional suppression is the major mechanism mediating homocysteine-induced endothelial cell growth inhibition
-
Wang H, Jiang XH, Yang F, Chapman GB, Durante W, Sibinga NES, Schafer AI (2002) Cyclin A transcriptional suppression is the major mechanism mediating homocysteine-induced endothelial cell growth inhibition. Blood 99: 939-945.
-
(2002)
Blood
, vol.99
, pp. 939-945
-
-
Wang, H.1
Jiang, X.H.2
Yang, F.3
Chapman, G.B.4
Durante, W.5
Sibinga, N.E.S.6
Schafer, A.I.7
-
121
-
-
34249730020
-
Efficacy of folic acid supplementation in stroke prevention: A meta-analysis
-
Wang X, Qin X, Demirtas H, Li J, Mao G, Huo Y, Sun N, Liu L, Xu X (2007) Efficacy of folic acid supplementation in stroke prevention: a meta-analysis. Lancet 369: 1876-1882.
-
(2007)
Lancet
, vol.369
, pp. 1876-1882
-
-
Wang, X.1
Qin, X.2
Demirtas, H.3
Li, J.4
Mao, G.5
Huo, Y.6
Sun, N.7
Liu, L.8
Xu, X.9
-
122
-
-
0345169177
-
Influence of hyperhomocysteinemia on the cellular redox state - impact on homocysteine-induced endothelial dysfunction
-
Weiss N, Heydrick SJ, Postea O, Keller C, Keaney JF, Loscalzo J (2003) Influence of hyperhomocysteinemia on the cellular redox state - impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med 41: 1455-1461.
-
(2003)
Clin Chem Lab Med
, vol.41
, pp. 1455-1461
-
-
Weiss, N.1
Heydrick, S.J.2
Postea, O.3
Keller, C.4
Keaney, J.F.5
Loscalzo, J.6
-
123
-
-
27444444053
-
Automated assay for the determination of methylmalonic acid, total homo-cysteine, and related amino acids in human serum or plasma by means of methylchloroformate derivatization and gas chromatography-mass spectrometry
-
Windelberg A, Arseth O, Kvalheim G, Ueland PM (2005) Automated assay for the determination of methylmalonic acid, total homo-cysteine, and related amino acids in human serum or plasma by means of methylchloroformate derivatization and gas chromatography-mass spectrometry. Clin Chem 51: 2103-2109.
-
(2005)
Clin Chem
, vol.51
, pp. 2103-2109
-
-
Windelberg, A.1
Arseth, O.2
Kvalheim, G.3
Ueland, P.M.4
-
124
-
-
0034624251
-
Effects of homocysteine on the binding of extracellular-superoxide dismutase to the endothelial cell surface
-
Yamamoto M, Hara H, Adachi T (2000) Effects of homocysteine on the binding of extracellular-superoxide dismutase to the endothelial cell surface. FEBS Lett 486: 159-162.
-
(2000)
FEBS Lett
, vol.486
, pp. 159-162
-
-
Yamamoto, M.1
Hara, H.2
Adachi, T.3
-
125
-
-
0035209718
-
Is homocysteine a pro-oxidant?
-
Zappacosta B, Mordente A, Persichilli S, Minucci A, Carlino P, Martorana GE, Giardina B, De Sole P (2001) Is homocysteine a pro-oxidant? Free Radical Res 35: 499-505.
-
(2001)
Free Radical Res
, vol.35
, pp. 499-505
-
-
Zappacosta, B.1
Mordente, A.2
Persichilli, S.3
Minucci, A.4
Carlino, P.5
Martorana, G.E.6
Giardina, B.7
De Sole, P.8
-
126
-
-
0042878460
-
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes
-
Zeng X, Dai J, Remick DG, Wang X (2003) Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes. Circ Res 93: 311-320.
-
(2003)
Circ Res
, vol.93
, pp. 311-320
-
-
Zeng, X.1
Dai, J.2
Remick, D.G.3
Wang, X.4
-
127
-
-
0035929641
-
Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response
-
Zhang C, Cai Y, Adachi MT, Oshiro S, Aso T, Kaufman RJ, Kitajima S (2001) Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response. J Biol Chem 276: 35867-35874.
-
(2001)
J Biol Chem
, vol.276
, pp. 35867-35874
-
-
Zhang, C.1
Cai, Y.2
Adachi, M.T.3
Oshiro, S.4
Aso, T.5
Kaufman, R.J.6
Kitajima, S.7
-
128
-
-
72449210573
-
Hyperhomo-cysteinemia promotes infammatory monocyte generation and accelerates atherosclerosis in transgenic cystathione b-synthase-deficient mice
-
Zhang D, Jiang X, Fang P, Yan Y, Song J, Gupta S, Schafer AI, Durante W, Kruger WD, Yang X, Wang H (2009) Hyperhomo-cysteinemia promotes infammatory monocyte generation and accelerates atherosclerosis in transgenic cystathione b-synthase-deficient mice. Circulation 120: 1893-1902.
-
(2009)
Circulation
, vol.120
, pp. 1893-1902
-
-
Zhang, D.1
Jiang, X.2
Fang, P.3
Yan, Y.4
Song, J.5
Gupta, S.6
Schafer, A.I.7
Durante, W.8
Kruger, W.D.9
Yang, X.10
Wang, H.11
-
129
-
-
0842303105
-
Comparing the ESA HPLC total homocysteine assay with electrochemical detection to the CDC in-house HPLC assay with fluorescence detection
-
Zhang M, Pfeiffer CM (2004) Comparing the ESA HPLC total homocysteine assay with electrochemical detection to the CDC in-house HPLC assay with fluorescence detection. Clin Chim Acta 340: 195-200.
-
(2004)
Clin Chim Acta
, vol.340
, pp. 195-200
-
-
Zhang, M.1
Pfeiffer, C.M.2
-
130
-
-
0033066640
-
Prostaglandin endoperoxide-de-pendent vasospasm in bovine coronary arteries after nitration of prostacyclin synthase
-
Zou M, Jendral M, Ullrich V (1999) Prostaglandin endoperoxide-de-pendent vasospasm in bovine coronary arteries after nitration of prostacyclin synthase. Br J Pharmacol 126: 1283-1292.
-
(1999)
Br J Pharmacol
, vol.126
, pp. 1283-1292
-
-
Zou, M.1
Jendral, M.2
Ullrich, V.3
-
131
-
-
78649652220
-
Homocysteine promotes proliferation and activation of microglia
-
Zou CG, Zhao YS, Gao SY, Li SD, Cao XZ, Zhang M, Zhang KQ (2010) Homocysteine promotes proliferation and activation of microglia. Neurobiol Aging 31: 2069-2079.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 2069-2079
-
-
Zou, C.G.1
Zhao, Y.S.2
Gao, S.Y.3
Li, S.D.4
Cao, X.Z.5
Zhang, M.6
Zhang, K.Q.7
|