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Volumn 29, Issue 1, 2009, Pages 157-165

Homocysteine reduces endothelial progenitor cells in stroke patients through apoptosis

Author keywords

Apoptosis; B vitamins; Endothelial progenitor cells; Homocysteine; Stroke

Indexed keywords

CASPASE 3; CASPASE 8; CYTOCHROME C; HOMOCYSTEINE; PYRIDOXINE;

EID: 58149173384     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2008.99     Document Type: Article
Times cited : (50)

References (44)
  • 1
    • 11144264350 scopus 로고    scopus 로고
    • Endothelial progenitor cells for neovascularization
    • Asahara T (2003) Endothelial progenitor cells for neovascularization. Ernst Schering Res Found Workshop 211-6
    • (2003) Ernst Schering Res Found Workshop , pp. 211-216
    • Asahara, T.1
  • 2
    • 0036226428 scopus 로고    scopus 로고
    • Endothelial progenitor cells for vascular regeneration
    • Asahara T, Isner JM (2002) Endothelial progenitor cells for vascular regeneration. J Hematother Stem Cell Res 11:171-8
    • (2002) J Hematother Stem Cell Res , vol.11 , pp. 171-178
    • Asahara, T.1    Isner, J.M.2
  • 3
    • 0033529618 scopus 로고    scopus 로고
    • Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization
    • Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, Kearne M, Magner M, Isner JM (1999a) Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 85:221-8
    • (1999) Circ Res , vol.85 , pp. 221-228
    • Asahara, T.1    Masuda, H.2    Takahashi, T.3    Kalka, C.4    Pastore, C.5    Silver, M.6    Kearne, M.7    Magner, M.8    Isner, J.M.9
  • 4
    • 0033565540 scopus 로고    scopus 로고
    • VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells
    • Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, Isner JM (1999b) VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J 18:3964-72
    • (1999) EMBO J , vol.18 , pp. 3964-3972
    • Asahara, T.1    Takahashi, T.2    Masuda, H.3    Kalka, C.4    Chen, D.5    Iwaguro, H.6    Inai, Y.7    Silver, M.8    Isner, J.M.9
  • 6
    • 0842325228 scopus 로고    scopus 로고
    • The immunoregulatory effects of homocysteine and its intermediates on T-lymphocyte function
    • Dawson H, Collins G, Pyle R, Deep-Dixit V, Taub DD (2004) The immunoregulatory effects of homocysteine and its intermediates on T-lymphocyte function. Mech Ageing Dev 125:107-10
    • (2004) Mech Ageing Dev , vol.125 , pp. 107-110
    • Dawson, H.1    Collins, G.2    Pyle, R.3    Deep-Dixit, V.4    Taub, D.D.5
  • 8
    • 0033525542 scopus 로고    scopus 로고
    • Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats in vivo
    • Dudman NP, Temple SE, Guo XW, Fu W, Perry MA (1999) Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats in vivo. Circ Res 84:409-16
    • (1999) Circ Res , vol.84 , pp. 409-416
    • Dudman, N.P.1    Temple, S.E.2    Guo, X.W.3    Fu, W.4    Perry, M.A.5
  • 9
    • 0027250615 scopus 로고
    • Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells
    • Fryer RH, Wilson BD, Gubler DB, Fitzgerald LA, Rodgers GM (1993) Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells. Arterioscler Thromb 13:1327-33
    • (1993) Arterioscler Thromb , vol.13 , pp. 1327-1333
    • Fryer, R.H.1    Wilson, B.D.2    Gubler, D.B.3    Fitzgerald, L.A.4    Rodgers, G.M.5
  • 12
    • 0041695231 scopus 로고    scopus 로고
    • Emerging risk factors for atherosclerotic vascular disease: A critical review of the evidence
    • Hackam DG, Anand SS (2003) Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence. JAMA 290:932-40
    • (2003) JAMA , vol.290 , pp. 932-940
    • Hackam, D.G.1    Anand, S.S.2
  • 13
    • 0026486960 scopus 로고
    • Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: A potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism
    • Harpel PC, Chang VT, Borth W (1992) Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: a potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism. Proc Natl Acad Sci USA 89:10193-7
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10193-10197
    • Harpel, P.C.1    Chang, V.T.2    Borth, W.3
  • 14
    • 0036999105 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, vascular function and atherosclerosis: Effects of vitamins
    • Haynes WG (2002) Hyperhomocysteinemia, vascular function and atherosclerosis: effects of vitamins. Cardiovasc Drugs Ther 16:391-9
    • (2002) Cardiovasc Drugs Ther , vol.16 , pp. 391-399
    • Haynes, W.G.1
  • 17
    • 0033554459 scopus 로고    scopus 로고
    • Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans
    • Kanani PM, Sinkey CA, Browning RL, Allaman M, Knapp HR, Haynes WG (1999) Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans. Circulation 100:1161-8
    • (1999) Circulation , vol.100 , pp. 1161-1168
    • Kanani, P.M.1    Sinkey, C.A.2    Browning, R.L.3    Allaman, M.4    Knapp, H.R.5    Haynes, W.G.6
  • 18
    • 0027421353 scopus 로고
    • Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease
    • Kang SS, Passen EL, Ruggie N, Wong PW, Sora H (1993) Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease. Circulation 88:1463-9
    • (1993) Circulation , vol.88 , pp. 1463-1469
    • Kang, S.S.1    Passen, E.L.2    Ruggie, N.3    Wong, P.W.4    Sora, H.5
  • 19
    • 0026633925 scopus 로고
    • Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease
    • Kang SS, Wong PW, Malinow MR (1992) Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease. Annu Rev Nutr 12:279-98
    • (1992) Annu Rev Nutr , vol.12 , pp. 279-298
    • Kang, S.S.1    Wong, P.W.2    Malinow, M.R.3
  • 20
    • 0037368292 scopus 로고    scopus 로고
    • Association between homocyst(e)ine levels and risk of vascular events
    • Kaplan ED (2003) Association between homocyst(e)ine levels and risk of vascular events. Drugs Today (Barc) 39:175-92
    • (2003) Drugs Today (Barc) , vol.39 , pp. 175-192
    • Kaplan, E.D.1
  • 21
    • 36148948608 scopus 로고    scopus 로고
    • Endothelial progenitor cells and cerebrovascular diseases
    • Lapergue B, Mohammad A, Shuaib A (2007) Endothelial progenitor cells and cerebrovascular diseases. Prog Neurobiol 83:349-62
    • (2007) Prog Neurobiol , vol.83 , pp. 349-362
    • Lapergue, B.1    Mohammad, A.2    Shuaib, A.3
  • 22
    • 37849035223 scopus 로고    scopus 로고
    • Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis
    • Mazumder S, Plesca D, Almasan A (2008) Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis. Methods Mol Biol 414:13-21
    • (2008) Methods Mol Biol , vol.414 , pp. 13-21
    • Mazumder, S.1    Plesca, D.2    Almasan, A.3
  • 23
    • 0029939676 scopus 로고    scopus 로고
    • Homocysteine and vascular disease
    • McCully KS (1996) Homocysteine and vascular disease. Nat Med 2:386-9
    • (1996) Nat Med , vol.2 , pp. 386-389
    • McCully, K.S.1
  • 24
    • 0028927607 scopus 로고
    • The Fas death factor
    • Nagata S, Golstein P (1995) The Fas death factor. Science 267:1449-56
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Golstein, P.2
  • 25
    • 34247339395 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis
    • Noor R, Shuaib U, Wang CX, Todd K, Ghani U, Schwindt B, Shuaib A (2007) High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis. Atherosclerosis 192:92-9
    • (2007) Atherosclerosis , vol.192 , pp. 92-99
    • Noor, R.1    Shuaib, U.2    Wang, C.X.3    Todd, K.4    Ghani, U.5    Schwindt, B.6    Shuaib, A.7
  • 29
    • 0033822684 scopus 로고    scopus 로고
    • Total homocysteine measurement in clinical practice
    • Rasmussen K, Moller J (2000) Total homocysteine measurement in clinical practice. Ann Clin Biochem 37(Part 5):627-48
    • (2000) Ann Clin Biochem , vol.37 , Issue.PART 5 , pp. 627-648
    • Rasmussen, K.1    Moller, J.2
  • 31
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH (1993) Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 270:2693-8
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.F.2    Wilson, P.W.3    Rush, D.4    Rosenberg, I.H.5
  • 33
    • 0027531427 scopus 로고
    • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
    • Stamler JS, Osborne JA, Jaraki O, Rabbani LE, Mullins M, Singel D, Loscalzo J (1993) Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest 91:308-18
    • (1993) J Clin Invest , vol.91 , pp. 308-318
    • Stamler, J.S.1    Osborne, J.A.2    Jaraki, O.3    Rabbani, L.E.4    Mullins, M.5    Singel, D.6    Loscalzo, J.7
  • 34
    • 0028918123 scopus 로고
    • Can lowering homocysteine levels reduce cardiovascular risk?
    • Stampfer MJ, Malinow MR (1995) Can lowering homocysteine levels reduce cardiovascular risk? N Engl J Med 332:328-9
    • (1995) N Engl J Med , vol.332 , pp. 328-329
    • Stampfer, M.J.1    Malinow, M.R.2
  • 36
    • 17644433975 scopus 로고    scopus 로고
    • Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    • Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, Martin H, Zeiher AM, Dimmeler S (2001) Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89:E1-7
    • (2001) Circ Res , vol.89
    • Vasa, M.1    Fichtlscherer, S.2    Aicher, A.3    Adler, K.4    Urbich, C.5    Martin, H.6    Zeiher, A.M.7    Dimmeler, S.8
  • 37
    • 0037022256 scopus 로고    scopus 로고
    • Fundamentals of endothelial function for the clinical cardiologist
    • Verma S, Anderson TJ (2002) Fundamentals of endothelial function for the clinical cardiologist. Circulation 105:546-9
    • (2002) Circulation , vol.105 , pp. 546-549
    • Verma, S.1    Anderson, T.J.2
  • 38
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • Wald DS, Law M, Morris JK (2002) Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 325:1202
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 39
    • 0345169177 scopus 로고    scopus 로고
    • Influence of hyperhomocysteinemia on the cellular redox state - impact on homocysteine-induced endothelial dysfunction
    • Weiss N, Heydrick SJ, Postea O, Keller C, Keaney JF, Jr, Loscalzo J (2003) Influence of hyperhomocysteinemia on the cellular redox state - impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med 41:1455-61
    • (2003) Clin Chem Lab Med , vol.41 , pp. 1455-1461
    • Weiss, N.1    Heydrick, S.J.2    Postea, O.3    Keller, C.4    Keaney Jr, J.F.5    Loscalzo, J.6
  • 40
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis
    • Welch GN, Loscalzo J (1998) Homocysteine and atherothrombosis. N Engl J Med 338:1042-50
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.N.1    Loscalzo, J.2
  • 41
    • 0041733082 scopus 로고    scopus 로고
    • Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury
    • Werner N, Junk S, Laufs U, Link A, Walenta K, Bohm M, Nickenig G (2003) Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ Res 93:e17-24
    • (2003) Circ Res , vol.93
    • Werner, N.1    Junk, S.2    Laufs, U.3    Link, A.4    Walenta, K.5    Bohm, M.6    Nickenig, G.7


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