Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice

FASEB Journal

Volumn 23, Issue 6, 2009, Pages 1721-1727

  Jakubowski, Hieronim ^a,b   Perła Kaján, Joanna ^a,b   Finnell, Richard H ^c   Cabrera, Robert M ^c   Wang, Hong ^d   Gupta, Sapna ^e   Kruger, Warren D ^e   Kraus, Jan P ^f   Shih, Diana M ^g  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b POZNA UNIVERSITY OF LIFE SCIENCES   (Poland)

^c TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^d TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e FOX CHASE CANCER CENTER   (United States)

^f Children's Hospital Colorado   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atherothrombosis; Liver damage; Methionine; Thiolactone

Indexed keywords

FOLIC ACID; HOMOCYSTEINE; LYSINE; METHIONINE; N HOMOCYSTEINE; THIOLACTONE; UNCLASSIFIED DRUG; CARRIER PROTEIN; CYSTATHIONINE BETA SYNTHASE; DRUG DERIVATIVE; HOMOCYSTEINE THIOLACTONE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; AUTOIMMUNITY; BRAIN DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; FOLATE METABOLISM; GENE; GENETIC DISORDER; HISTOPATHOLOGY; HYPERHOMOCYSTEINEMIA; LIVER DISEASE; MOUSE; NONHUMAN; NUTRITIONAL DISORDER; PCFT GENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN FOLDING; PROTEIN INTAKE; THROMBOSIS; ANIMAL; C57BL MOUSE; DIET; GENETICS; HUMAN; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY;

ANIMALIA; MUS;

ANIMALS; CYSTATHIONINE BETA-SYNTHASE; DIET; FOLIC ACID; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; LIVER; MEMBRANE TRANSPORT PROTEINS; METHIONINE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 67649371083     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-127548     Document Type: Article

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