The determination of homocysteine-thiolactone in human plasma

Analytical Biochemistry

Volumn 337, Issue 2, 2005, Pages 271-277

  Chwatko, Grazyna ^a   Jakubowski, Hieronim ^a,b  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b POLISH ACADEMY OF SCIENCES   (Poland)

Author keywords

Homocysteine thiolactone; HPLC; Human plasma

Indexed keywords

CHLORINE COMPOUNDS; COLUMN CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES;

CARDIO-VASCULAR DISEASE; DETECTION AND QUANTIFICATIONS; HOMOCYSTEINES; HPLC; HUMAN PLASMA SAMPLES; HUMAN PLASMAS; POST-COLUMN DERIVATIZATION; REACTIVE METABOLITES;

PLASMA (HUMAN);

CHLOROFORM; HOMOCYSTEINE THIOLACTONE; METHANOL; PHTHALALDEHYDE;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD CHEMISTRY; BLOOD LEVEL; CATION EXCHANGE; COHORT ANALYSIS; EXTRACTION; FEMALE; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; STANDARD; ULTRAFILTRATION;

EID: 13244287981     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.11.035     Document Type: Article

References (34)

1. R. Clarke and Homocysteine Studies Collaboration, Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis, J. Am. Med. Assoc. 288 (2002) 2015-2022
2. S. Seshadri, A. Beiser, J. Selhub, P.F. Jacques, I.H. Rosenberg, R.B. D'Agostino, P.W. Wilson, and P.A. Wolf Plasma homocysteine as a risk factor for dementia and Altzheimer's disease N. Engl. J. Med. 346 2002 476 483
3. A.B. Lawrence de Konig, G.H. Werstuck, J. Zhou, and R.C. Austin Hyperhomocysteinemia and its role in the development of atherosclerosis Clin. Biochem. 36 2003 431 441
4. H. Jakubowski Molecular basis of homocysteine toxicity in humans Cell. Mol. Life Sci. 61 2004 470 487
5. H. Jakubowski Homocysteine-thiolactone and S-nitroso-homocysteine mediate incorporation of homocysteine into protein in humans Clin. Chem. Lab. Med. 41 2003 1462 1466
6. H. Jakubowski Translational accuracy of aminoacyl-tRNA synthetases: implications for atherosclerosis J. Nutr. 131 suppl 2001 2983 2987
7. H. Jakubowski The determination of homocysteine-thiolactone in biological samples Anal. Biochem. 308 2002 112 119
8. L.A. Harker, S.J. Slichter, C.R. Scott, and R. Ross Homocystinemia: vascular injury and arterial thrombosis N. Engl. J. Med. 291 1974 537 541
9. M. Langmeier, J. Folbergrova, R. Haugvicova, J. Pokorny, and P.T. Mares Neuronal cell death in hippocampus induced by homocysteic acid in immature rats Epilepsia 44 2003 299 304
10. N.E. Greene, L.E. Dunlevy, and A.J. Copp Homocysteine is embryotoxic but does not cause neural tube defects in mouse embryos Anat. Embryol. (Berl) 206 2003 185 191
11. L.A. Van Aertes, H.H. Klaasboer, N.S. Postma, J.C. Pertijs, J.H. Peereboom, T.K. Eskes, and J. Noordhoek Stereospecific in vitro embryotoxicity of l-homocysteine in pre- and post-implantation rodent embryos Toxic. In Vitro 6 1993 743 749
12. T.H. Rosenquist, S.A. Ratashak, and J. Selhub Homocysteine induces congenital defects of the heart and neural tube: effect of folic acid Proc. Natl. Acad. Sci. USA 93 1996 15227 15232
13. D.K. Hansen, F. Grafton, S. Melnyk, and J.S. James Lack of embryotoxicity of homocysteine thiolactone in mouse embryos in vitro Reprod. Toxicol. 15 2001 239 244
14. P. Mercie, O. Garnier, L. Lascoste, M. Renard, C. Closse, F. Durrieu, G. Marit, R.M. Boisseau, and F. Belloc Homocysteine thiolactone induces caspase-independent vascular endothelial cell death with apoptotic features Apoptosis 5 2000 403 411
15. R.F. Huang, S.M. Huang, B.S. Lin, J.S. Wei, and T.Z. Liu Homocysteine thiolactone induces apoptotic DNA damage mediated by increased intracellular hydrogen peroxide and caspase 3 activation in HL-60 cells Life Sci. 68 2001 2799 2811
16. S. Najib, and V. Sanchez-Margalet Homocysteine thiolactone inhibits insulin signaling and glutathione has a protective effect J. Mol. Endocrinol. 27 2001 85 91
17. H. Jakubowski Metabolism of homocysteine thiolactone in human cell cultures: possible mechanism for pathological consequences of elevated homocysteine levels J. Biol. Chem. 272 1997 1935 1941
18. H. Jakubowski, L. Zhang, A. Bardeguez, and A. Aviv Homocysteine thiolactone and protein homocysteinylation in human endothelial cells: implications for atherosclerosis Circ. Res. 87 2000 45 51
19. H. Jakubowski Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels FASEB J. 13 1999 2277 2283
20. H. Jakubowski Homocysteine is a protein amino acid in humans: implications for homocysteine-linked disease J. Biol. Chem. 277 2002 30425 30428
21. R. Głowacki, and H. Jakubowski Cross-talk between Cys-34 and lysine residues in human serum albumin revealed by N-homocysteinylation J. Biol. Chem. 279 2004 10864 10871
22. G. Ferretti, T. Bacchetti, E. Marotti, and G.T. Curatola Effect of homocysteinylation on human high-density lipoproteins: a correlation with paraoxonase activity Metabolism 52 2003 146 151
23. G. Ferretti, T. Bacchetti, C. Moroni, A. Vignini, L. Nanetti, and G.T. Curatola Effects of homocysteinylation on low density lipoprotein peroxidation of human endothelial cells J. Cell. Biochem. 92 2004 351 360
24. E. Ferguson, S. Parthasarathy, J. Joseph, and B. Kalyanaraman Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low-density lipoprotein J. Lipid Res. 39 1998 925 933
25. A. Undas, J. Perła, M. Łaciñski, W. Trzeciak, R. Kazmierski, and H. Jakubowski Autoantibodies against N-homocysteinylated proteins in humans: implications for atherosclerosis Stroke 35 2004 1299 1304
26. P. Daneshvar, M. Yazdanpanah, C. Cuthbert, and D.E. Cole Quantitative assay of plasma homocysteine thiolactone by gas chromatography/mass spectrometry Rapid. Commun. Mass. Spectrom. 17 2003 258 262
27. H. Jakubowski Calcium-dependent human serum homocysteine thiolactone hydrolase: a protective mechanism against protein N-homocysteinylation J. Biol. Chem. 275 2000 3957 3962
28. H. Jakubowski, W. Ambrosius, and J.H. Pratt Genetic determinants of homocysteine thiolactonase activity in humans: implications for atherosclerosis FEBS Lett. 491 2001 35 39
29. R.F. Anderson, and J.E. Packer The radiolysis of aqueous solutions of homocysteine thiolactone Int. J. Radiat. Phys. Chem. 6 1974 33 46
30. H. Jakubowski, and A. Guranowski Metabolism of homocysteine-thiolactone in plants J. Biol. Chem. 278 2003 6765 6770
31. Y. Mukai, T. Togawa, T. Suzuki, K. Ohata, and S. Tanabe Determination of homocysteine thiolactone and homocysteine in cell cultures using high-performance liquid chromatography with fluorescence detection J. Chromatogr. B 767 2002 263 268
32. N.P. Dudman, C. Hicks, J.F. Lynch, D.E. Wilcken, and J. Wang Homocysteine thiolactone disposal by human arterial endothelial cells and serum in vitro Arterioscler. Thromb. 11 1991 663 670
33. S. Sengupta, H. Chen, T. Togawa, P.M. DiBello, A.K. Majors, B. Budy, M.E. Ketterer, and D.W. Jacobsen Albumin thiolate anion is an intermediate in the formation of albumin-S-S-homocysteine J. Biol. Chem. 276 2001 30111 30117
34. S.H. Mudd, J.D. Finkelstein, H. Refsum, P.M. Ueland, M.R. Malinow, S.R. Lentz, D.W. Jacobsen, L. Brattstrom, B. Wilcken, D.E. Wilcken, H.J. Blom, S.P. Stabler, R.H. Allen, J. Selhub, and I.H. Rosenberg Homocysteine and its disulfide derivatives: a suggested consensus terminology Arterioscler. Thromb. Vasc. Biol. 20 2000 1704 1706