Is homocysteine a pro-oxidant?

Free Radical Research

Volumn 35, Issue 5, 2001, Pages 499-505

  Zappacosta, Bruno ^a   Mordente, Alvaro ^a   Persichilli, Silvia ^a   Minucci, Angelo ^a   Carlino, Paola ^a   Martorana, Giuseppe ^a   Giardina, Bruno ^a   De Sole, Pasquale ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Antioxidants; Chemiluminescence; Homocysteine; Hydrogen peroxide; Oxidants

Indexed keywords

FERRYLMYOGLOBIN; HOMOCYSTEINE; HYDROGEN PEROXIDE; HYPOCHLORITE; LUMINOL; METAL; METMYOGLOBIN; OXIDIZING AGENT; PEROXYNITRITE; RHODAMINE;

ARTICLE; ATHEROSCLEROSIS; BLOOD LEVEL; CARDIOVASCULAR DISEASE; CATALYSIS; CHEMICAL INTERACTION; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; OXIDATION; PATHOPHYSIOLOGY;

EID: 0035209718     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760100301511     Document Type: Article

References (29)

1. "Disorders on transsulfuration"
2. "Plasma homoysteine, a risk factor for vascular disease: Plasma levels in health, disease and drug therapy"
3. "Homocyst(e)ine and arterial occlusive diseases"
4. "Homocysteine and thrombotic disease"
5. "Prevalence of mild hyperhomocysteinemia and association with thrombofilic genotypes (Factor V Leiden and prothrombin G20210A) in Italian patients with venous thromboembolic disease"
6. "Activation of Hageman factor by L-homocysteine"
7. "Activation of endogenous factor V by homocysteine-induced vascular endothelial cell activator"
8. "Homocysteine, an atherogenic stimulus, reduces protein C activation by arterial and venous endothelial cells"
9. "Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen"
10. "Promotion of vascular smooth muscle cell growth by homocysteine: A link to atherosclerosis"
11. "Endothelial cell injury due copper-catalyzed hydrogen peroxide generation from homocysteine"
12. "The oxidant stress of hyperhomocysteinemia"
13. "Homocysteine metabolism and the oxidative modification of proteins and lipids"
14. "The chemistry of peroxinitrite: A product from the reaction of nitric oxide with superoxide"
15. "Human arterial endothelial cell detachment in vitro: Its promotion by homocysteine and cysteine"
16. "Superoxide-dependent cerebrovascular effects of homocysteine"
17. "Effect of homocysteine on polymorphonuclear leukocytes activity and luminol-dependent chemiluminescence"
18. "The haemolytic activity of homocysteine is increased by the activated polymorphonuclear leukocytes"
19. "A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: Applications in detecting the activity of phagocyte NADPH oxidase and other oxidases"
20. "Ferrylmyoglobin: Formation and chemical reactivity toward electron donating compounds"
21. "Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detector"
22. "Redox cycling of myoglobin and ascorbate: A potential protective mechanism against oxidative reperfusion injury in muscle"
23. "Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxinitrite"
24. "Oxidation of low density lipoprotein by thiols: Superoxide-dependent and -independent mechanisms"
25. "Homocysteine and occlusive vascular disease: Culprit or bystander?"
26. The Neutrophil: Function and Clinical Disordes
27. "The copper catalyzed oxidation of cysteine to cystine"
28. "An alternative view of homocysteine"