Thermosensitive hydrogels for nasal drug delivery: The formulation and characterisation of systems based on N-trimethyl chitosan chloride

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 77, Issue 2, 2011, Pages 225-232

  Nazar, H ^a   Fatouros, D G ^a   Van Der Merwe, S M ^a   Bouropoulos, N ^b,c   Avgouropoulos, G ^b,c   Tsibouklis, J ^a   Roldo, M ^a  

^a UNIVERSITY OF PORTSMOUTH   (United Kingdom)

^b UNIVERSITY OF PATRAS   (Greece)

^c INSTITUTE OF CHEMICAL ENGINEERING SCIENCES   (Greece)

Author keywords

Chitosan; Hydrogel; Mucoadhesion; N trimethyl chitosan chloride; Nasal drug delivery; Thermosensitive

Indexed keywords

CHITOSAN DERIVATIVE; CHLORIDE; GLYCEROPHOSPHATE; MACROGOL 4000; MUCIN; N TRIMETHYLCHITOSAN CHLORIDE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL INTERACTION; CHEMICAL MODIFICATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; FLOW KINETICS; GELATION; HEAT SENSITIVITY; HYDROGEL; MOLECULAR WEIGHT; MUCOADHESION; PHASE TRANSITION; PHYSICAL CHEMISTRY; QUATERNIZATION; SYNTHESIS; TEMPERATURE SENSITIVITY; VISCOELASTICITY; VISCOSITY; WETTABILITY; YOUNG MODULUS;

ADMINISTRATION, INTRANASAL; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGELS; MUCOCILIARY CLEARANCE; PHASE TRANSITION; PHYSICOCHEMICAL PHENOMENA; RHEOLOGY; TEMPERATURE; TRANSITION TEMPERATURE; VISCOSITY; WATER;

EID: 79551566691     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.11.022     Document Type: Article

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