Pseudo-thermosetting chitosan hydrogels for biomedical application

International Journal of Pharmaceutics

Volumn 288, Issue 1, 2005, Pages 17-25

  Berger, J ^a   Reist, M ^a   Chenite, A ^b   Felt Baeyens, O ^c   Mayer, J M ^a   Gurny, R ^c  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b Biosyntech   (Canada)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Chitosan; Drug delivery system; Hydrogel; Reacetylation; Turbidity

Indexed keywords

ACETIC ANHYDRIDE; CHITOSAN; GLYCEROL 2 PHOSPHATE; MONOMER;

ACETYLATION; ARTICLE; BIOMEDICINE; DILUTION; DRUG ACTIVITY; DRUG FORMULARY; DRUG SYNTHESIS; HEAT SENSITIVITY; HYDROGEL; PRIORITY JOURNAL; REPRODUCIBILITY; TECHNIQUE; TEMPERATURE DEPENDENCE; TURBIDITY;

BIOMEDICAL TECHNOLOGY; CHITOSAN; HYDROGELS; SCATTERING, RADIATION; TEMPERATURE;

EID: 10644229155     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.07.036     Document Type: Article

References (25)

1. S. Aiba Studies on chitosan: 3. Evidence for the presence of random and block copolymer structures in partially N-acetylated chitosans Int. J. Biol. Macromol. 13 1991 40 44
2. S. Aiba Preparation of N-acetylchitooligosaccharides from lysozymic hydrolisates of partially N-acetylated chitosans Carbohydr. Res. 261 1994 297 306
3. H. Baumann, and V. Faust Concepts for improved regioselective placement of O-sulfo, N-sulfo, N-acetyl, and N-carboxymethyl groups in chitosan derivatives Carbohydr. Res. 331 2001 43 57
4. Berger, J., Reist, M., Galland, A., Felt, O., Gurny, R., 2004. Mechanism of gelation and structure in chitosan/β-glycerophosphate hydrogels. J. Pharm. Sci., submitted for publication.
5. A. Chenite, M. Buschmann, D. Wang, C. Chaput, and N. Kandani Rheological characterisation of thermogelling chitosan/glycero-phosphate solutions Carbohydr. Polym. 46 2001 39 47
6. A. Chenite, C. Chaput, D. Wang, C. Combes, M.D. Buschmann, C.D. Hoemann, J.-C. Leroux, B.L. Atkinson, F. Binette, and A. Selmani Novel injectable neutral solutions of chitosan form biodegradable gels in situ Biomaterials 21 2000 2155 2161
7. A. Domard Physical, physicochemical and biological properties of chitin/chitosan: biomedical applications R. Gurny Proceedings of the Conference Archamps 6ème rencontre 2000
8. O. Felt, P. Furrer, J.M. Mayer, B. Plazonnet, P. Buri, and R. Gurny Topical use of chitosan in ophthalmology: tolerance assessment and evaluation of precorneal retention Int. J. Pharm. 180 1999 185 193
9. S. Hirano, Y. Ohe, and H. Ono Selective N-acylation of chitosan Carbohydr. Res. 47 1976 315 320
10. S. Hirano, and R. Yamaguchi N-Acetyl chitosan gel: a polyhydrate of chitin Biopolymers 15 1976 1685 1691
11. 13C=O] Acetylchitosan and its digestibility by silkworms Carbohydr. Polym. 22 1993 137 140
12. W. Horwitz Beverages W. Horwitz Methods of Analysis of the Association of Official Agricultural Chemists 1960 AOAC Washington 116 117
13. J.Z. Knaul, M.R. Kasaai, V.T. Bui, and K.A.M. Creber Characterization of deacetylated chitosan and chitosan molecular weight review Can. J. Chem. 76 1998 1699 1706
14. K. Kurita, M. Kamiya, and S.I. Nishimura Solubilization of a rigid polysaccharide: controlled partial N-acetylation of chitosan to develop solubility Carbohydr. Polym. 16 1991 83 92
15. K. Kurita, T. Sannan, and Y. Iwakura Studies on chitin: evidence for formation of block and random copolymers of N-acetyl-d-glucosamine and d-glucosamine by hetero and homogeneous hydrolyses Makromol. Chem. 178 1977 3197 3202
16. A. Martinou, D. Kafetzopoulos, and V. Bouriotis Chitin deacetylation by enzymatic means: monitoring of deacetylation processes Carbohydr. Res. 273 1995 235 242
17. C. Milot, J. McBrien, S. Allen, and E. Guibal Influence of physicochemical and structural characteristics of chitosan flakes on molybdate sorption J. Appl. Polymer Sci. 68 1998 571 580
18. M. Mucha Rheological characteristics of semi-dilute chitosan solutions Macromol. Chem. Phys. 198 1997 471 484
19. R. Muzzarelli Chitosan R. Muzzarelli Natural Chelating Polymers 1973 Pergamon Press Oxford 144 176
20. R.A.A. Muzzarelli, and R. Rocchetti The determination of the degree of acetylation of chitosans by spectrophotometry R.A.A. Muzzarelli C. Jeuniaux G.W. Gooday Chitin in Nature and Technology 1986 Plenum Press New York 385 388
21. K. Ogawa, and T. Yui Crystallinity of partially N-acetylated chitosans Biosci. Biotech. Biochem. 57 1993 1466 1469
22. H. Saimoto, and Y. Shigemasa Desalting of chitin derivatives by the electrodialysis via ion-exchange membranes Polym. Adv. Technol. 10 2000 39 42
23. 1Synthesis of water-soluble chitosan derivatives by symple acetylation Biomacromolecules 3 2002 1126 1128
24. L. Vachoud, N. Zydowicz, and A. Domard Formation and characterisation of a physical chitin gel Carbohydr. Res. 302 1997 169 177
25. L. Vachoud, N. Zydowicz, and A. Domard Physicochemical behaviour of chitin gels Carbohydr. Res. 326 2000 295 304