A thermosensitive hydrogel based on quaternized chitosan and poly(ethylene glycol) for nasal drug delivery system

Biomaterials

Volumn 28, Issue 13, 2007, Pages 2220-2232

  Wu, Jie ^a,b   Wei, Wei ^a,b   Wang, Lian Yan ^a   Su, Zhi Guo ^a   Ma, Guang Hui ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Absorption enhancer; Hydrogel; N (2 hydroxy 3 trimethylammonium) propyl chitosan chloride; Nasal drug delivery system; Poly(ethylene glycol)

Indexed keywords

ABSORPTION ENHANCER; CONFOCAL LASER SCANNING MICROSCOPY (CLSM); EPITHELIAL CELLS; N-[(2-HYDROXY-3-TRIMETHYLAMMONIUM) PROPYL] CHITOSAN CHLORIDE; NASAL DRUG DELIVERY SYSTEMS;

CONTROLLED DRUG DELIVERY; GLUCOSE; MIXING; PHASE TRANSITIONS; POLYETHYLENE GLYCOLS; POLYSACCHARIDES;

HYDROGELS;

ALPHA BETA GLYCEROPHOSPHATE; CHITOSAN DERIVATIVE; FLUORESCEIN ISOTHIOCYANATE; GLUCOSE; GLYCEROPHOSPHATE; MACROGOL; MACROGOL 1000; MACROGOL 2000; MACROGOL 4000; MACROGOL 6000; MACROGOL 8000; MACROGOL DERIVATIVE; METHOXYPOLYETHYLENE GLYCOL 2000; METHOXYPOLYETHYLENE GLYCOL 5000; N [(2 HYDROXY 3 TRIMETHYLAMMONIUM)PROPYL]CHITOSAN CHLORIDE; RECOMBINANT HUMAN INSULIN; UNCLASSIFIED DRUG;

ABSORPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CHEMICAL LABELING; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; EPITHELIUM CELL; GLUCOSE BLOOD LEVEL; HEAT SENSITIVITY; HYDROGEL; IN VITRO STUDY; MALE; NONHUMAN; NOSE CAVITY; NOSE MUCOSA; PRIORITY JOURNAL; RAT; ROOM TEMPERATURE; SLOW DRUG RELEASE;

ABSORPTION; ANIMALS; BLOOD GLUCOSE; CHITOSAN; DRUG DELIVERY SYSTEMS; EPITHELIAL CELLS; GLYCEROPHOSPHATES; HYDROGELS; INSULIN; MALE; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; TEMPERATURE;

RATTUS;

EID: 33846804547     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.12.024     Document Type: Article

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