Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3β pathway in ginsenoside Rb1's attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation

Journal of Ethnopharmacology

Volumn 133, Issue 3, 2011, Pages 1109-1116

  Zhao, Ruiping ^a   Zhang, Zhaoxu ^a   Song, Yuejia ^a   Wang, Desheng ^a   Qi, Jiping ^a   Wen, Shirong ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Ginsenoside Rb1; Glycogen synthase kinase 3 (GSK 3 ); Phosphoinositide 3 kinase (PI3K); Tau

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMYLOID BETA PROTEIN[1-42]; AMYLOID PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GINSENOSIDE RB 1; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TAU PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BLOTTING, WESTERN; GINSENOSIDES; GLYCOGEN SYNTHASE KINASE 3; MICROSCOPY, FLUORESCENCE; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; TAU PROTEINS;

PANAX GINSENG;

EID: 79551543865     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.11.054     Document Type: Article

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