Intravenous infusion of dihydroginsenoside Rb1 prevents compressive spinal cord injury and ischemic brain damage through upregulation of VEGF and Bcl-xL

Journal of Neurotrauma

Volumn 24, Issue 6, 2007, Pages 1037-1054

  Sakanaka, Masahiro ^a   Zhu, Pengxiang ^a   Zhang, Bo ^a   Wen, Tong Chun ^a   Cao, Fang ^a   Ma, Yong Jie ^a   Samukawa, Keiichi ^a   Mitsuda, Noriaki ^a   Tanaka, Junya ^a   Kuramoto, Makoto ^b   Uno, Hidemitsu ^b   Hata, Ryuji ^a  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b EHIME UNIVERSITY   (Japan)

Author keywords

Bcl xL; Cerebral ischemia; Ginsenoside Rb1; Spinal cord injury; VEGF

Indexed keywords

ANGIOGENIC FACTOR; DIHYDROGINSENOSIDE RB 1; GINSENOSIDE RB 1; NEUROTROPHIC FACTOR; PROTEIN BCL XL; STAT5 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN TEMPERATURE; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; GENE EXPRESSION; GINSENG; IN VITRO STUDY; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; SPINAL CORD COMPRESSION; SPINAL CORD INJURY;

ANIMALS; BCL-X PROTEIN; BRAIN INFARCTION; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GINSENOSIDES; INFUSIONS, INTRAVENOUS; MALE; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; RATS; RATS, INBRED SHR; RATS, WISTAR; RNA, MESSENGER; SPINAL CORD COMPRESSION; STAT5 TRANSCRIPTION FACTOR; TREATMENT OUTCOME; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34347339390     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2006.0182     Document Type: Article

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