Neuroprotective effects of donepezil through inhibition of GSK-3 activity in amyloid-β-induced neuronal cell death

Journal of Neurochemistry

Volumn 108, Issue 5, 2009, Pages 1116-1125

  Noh, Min Young ^a   Koh, Seong Ho ^a   Kim, Youngchul ^a   Kim, Hyun Young ^a   Cho, Goang Won ^a   Kim, Seung Hyun ^a  

^a Hanyang University   (South Korea)

Author keywords

Amyloid ; Donepezil; Glycogen synthase kinase 3; Neuroprotection; Nicotinic acetylcholine receptors; Phosphoinositide 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; AMYLOID BETA PROTEIN[1-42]; DONEPEZIL; GALANTAMINE; GLYCOGEN SYNTHASE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; HUPERZINE A; MECAMYLAMINE; NICOTINIC RECEPTOR; PROTEIN KINASE B; TAU PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; NERVE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT;

AMYLOID BETA-PROTEIN; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CHOLINESTERASE INHIBITORS; CHROMONES; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; GLYCOGEN SYNTHASE KINASE 3; INDANS; INDOLES; MECAMYLAMINE; MORPHOLINES; NEURONS; NEUROPROTECTIVE AGENTS; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; SERINE; SINCALIDE;

RATTUS;

EID: 59449087438     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05837.x     Document Type: Article

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