-
1
-
-
0242664588
-
Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418
-
Bhat R., Xue Y., Berg S., Hellberg S., Ormo M., Nilsson Y., Radesater A.C., Jerning E., Markgren P.O., Borgegard T., Nylof M., Gimenez-Cassina A., Hernandez F., Lucas J.J., Diaz-Nido J., and Avila J. Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J. Biol. Chem. 278 (2003) 45937-45945
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 45937-45945
-
-
Bhat, R.1
Xue, Y.2
Berg, S.3
Hellberg, S.4
Ormo, M.5
Nilsson, Y.6
Radesater, A.C.7
Jerning, E.8
Markgren, P.O.9
Borgegard, T.10
Nylof, M.11
Gimenez-Cassina, A.12
Hernandez, F.13
Lucas, J.J.14
Diaz-Nido, J.15
Avila, J.16
-
2
-
-
0033773645
-
Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSTF-1 activity.
-
Bijur G.N., and Jope R.S. Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSTF-1 activity. J. Neurochem. 75 (2000) 2401-2408
-
(2000)
J. Neurochem.
, vol.75
, pp. 2401-2408
-
-
Bijur, G.N.1
Jope, R.S.2
-
3
-
-
0035813212
-
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta
-
Bijur G.N., and Jope R.S. Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. J. Biol. Chem. 276 (2001) 37436-37442
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37436-37442
-
-
Bijur, G.N.1
Jope, R.S.2
-
4
-
-
0037200117
-
Oligomeric and fibrillar species of amyloidbeta peptides differentially affect neuronal viability
-
Dahlgren K.N., Manelli A.M., Stine Jr. W.B., Baker L.K., Krafft G.A., and LaDu M.J. Oligomeric and fibrillar species of amyloidbeta peptides differentially affect neuronal viability. J. Biol. Chem. 277 (2002) 32046-32053
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
5
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
-
Embi N., Rylatt D.B., and Cohen P. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur. J. Biochem. 107 (1980) 519-527
-
(1980)
Eur. J. Biochem.
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
6
-
-
0141842655
-
Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide
-
Filomeni G., Aquilano K., Rotilio G., and Ciriolo M.R. Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide. Cancer Res. 63 (2003) 5940-5949
-
(2003)
Cancer Res.
, vol.63
, pp. 5940-5949
-
-
Filomeni, G.1
Aquilano, K.2
Rotilio, G.3
Ciriolo, M.R.4
-
7
-
-
0037443604
-
Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation
-
Ghribi O., Herman M.M., and Savory J. Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation. J. Neurosci. Res. 71 (2003) 853-862
-
(2003)
J. Neurosci. Res.
, vol.71
, pp. 853-862
-
-
Ghribi, O.1
Herman, M.M.2
Savory, J.3
-
8
-
-
10644255687
-
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
-
Gould T.D., Einat H., Bhat R., and Manji H.K. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int. J. Neuropsychopharmacol. 7 (2004) 387-390
-
(2004)
Int. J. Neuropsychopharmacol.
, vol.7
, pp. 387-390
-
-
Gould, T.D.1
Einat, H.2
Bhat, R.3
Manji, H.K.4
-
9
-
-
0034859101
-
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling
-
Grimes C.A., and Jope R.S. The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog. Neurobiol. 65 (2001) 391-426
-
(2001)
Prog. Neurobiol.
, vol.65
, pp. 391-426
-
-
Grimes, C.A.1
Jope, R.S.2
-
10
-
-
0036323445
-
Alzheimer disease and cerebrovascular pathology: an update
-
Jellinger K.A. Alzheimer disease and cerebrovascular pathology: an update. J. Neural Trans. 109 (2002) 813-836
-
(2002)
J. Neural Trans.
, vol.109
, pp. 813-836
-
-
Jellinger, K.A.1
-
11
-
-
0031593592
-
Neuropathology of Alzheimer's disease: a critical update
-
Jellinger K.A., and Bancher C. Neuropathology of Alzheimer's disease: a critical update. J. Neural Transm., Suppl. 54 (1998) 77-95
-
(1998)
J. Neural Transm., Suppl.
, vol.54
, pp. 77-95
-
-
Jellinger, K.A.1
Bancher, C.2
-
12
-
-
0033951989
-
Diphosphorylation and involvement of extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons
-
Jiang Q., Gu Z., Zhang G., and Jin G. Diphosphorylation and involvement of extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons. Brain Res. 857 (2000) 71-77
-
(2000)
Brain Res.
, vol.857
, pp. 71-77
-
-
Jiang, Q.1
Gu, Z.2
Zhang, G.3
Jin, G.4
-
13
-
-
0442276554
-
The glamour and gloom of glycogen synthase kinase-3
-
Jope R.S., and Johnson G.V. The glamour and gloom of glycogen synthase kinase-3. Trends Biochem. Sci. 29 (2004) 95-102
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 95-102
-
-
Jope, R.S.1
Johnson, G.V.2
-
14
-
-
0035903090
-
Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels
-
Kirschenbaum F., Hsu S.C., Cordell B., and McCarthy J.V. Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels. J. Biol. Chem. 276 (2001) 30701-30707
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30701-30707
-
-
Kirschenbaum, F.1
Hsu, S.C.2
Cordell, B.3
McCarthy, J.V.4
-
15
-
-
10744223843
-
Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3
-
Koh S.H., Kim S.H., Kwon H., Park Y., Kim K.S., Song C.W., Kim J., Kim M.H., Yu H.J., Henkel J.S., and Jung H.K. Epigallocatechin gallate protects nerve growth factor differentiated PC12 cells from oxidative-radical-stress-induced apoptosis through its effect on phosphoinositide 3-kinase/Akt and glycogen synthase kinase-3. Brain Res. Mol. Brain Res. 118 (2003) 72-81
-
(2003)
Brain Res. Mol. Brain Res.
, vol.118
, pp. 72-81
-
-
Koh, S.H.1
Kim, S.H.2
Kwon, H.3
Park, Y.4
Kim, K.S.5
Song, C.W.6
Kim, J.7
Kim, M.H.8
Yu, H.J.9
Henkel, J.S.10
Jung, H.K.11
-
16
-
-
3543001698
-
Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells.
-
Koh S.H., Kim S.H., Kwon H., Kim J.G., Kim J.H., Yang K.H., Kim J., Kim S.U., Yu H.J., Do B.R., Kim K.S., and Jung H.K. Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells. Neurotoxicology 25 (2004) 793-802
-
(2004)
Neurotoxicology
, vol.25
, pp. 793-802
-
-
Koh, S.H.1
Kim, S.H.2
Kwon, H.3
Kim, J.G.4
Kim, J.H.5
Yang, K.H.6
Kim, J.7
Kim, S.U.8
Yu, H.J.9
Do, B.R.10
Kim, K.S.11
Jung, H.K.12
-
17
-
-
31944437691
-
2 induced death of neuronal-differentiated PC12 cells
-
2 induced death of neuronal-differentiated PC12 cells. J. Korean Neurol. Assoc. 22 (2004) 375-381
-
(2004)
J. Korean Neurol. Assoc.
, vol.22
, pp. 375-381
-
-
Koh, S.H.1
Kwon, H.2
Park, Y.3
Kim, J.G.4
Kim, K.S.5
Song, C.W.6
Kim, J.H.7
Kim, J.8
Kim, M.H.9
Kim, K.S.10
Yu, H.J.11
Jung, H.G.12
Kim, S.H.13
-
18
-
-
23244436178
-
Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene
-
Koh S.H., Lee Y.B., Kim K.S., Kim H.J., Kim M., Lee Y.J., Kim J., Lee K.W., and Kim S.H. Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene. Eur. J. Neurosci. 22 (2005) 301-309
-
(2005)
Eur. J. Neurosci.
, vol.22
, pp. 301-309
-
-
Koh, S.H.1
Lee, Y.B.2
Kim, K.S.3
Kim, H.J.4
Kim, M.5
Lee, Y.J.6
Kim, J.7
Lee, K.W.8
Kim, S.H.9
-
19
-
-
33845989064
-
Glycogen synthase kinase-3β activity plays very important roles in determining the fate of oxidative stress-inflicted neuronal cells
-
Lee K.Y., Koh S.H., Noh M.Y., Park K.W., Lee Y.J., and Kim S.H. Glycogen synthase kinase-3β activity plays very important roles in determining the fate of oxidative stress-inflicted neuronal cells. Brain Res. 1129 (2007) 89-99
-
(2007)
Brain Res.
, vol.1129
, pp. 89-99
-
-
Lee, K.Y.1
Koh, S.H.2
Noh, M.Y.3
Park, K.W.4
Lee, Y.J.5
Kim, S.H.6
-
20
-
-
0036273020
-
Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
-
Martinez A., Castro A., Dorronsoro I., and Alonso M. Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation. Med. Res. Rev. 22 (2002) 373-384
-
(2002)
Med. Res. Rev.
, vol.22
, pp. 373-384
-
-
Martinez, A.1
Castro, A.2
Dorronsoro, I.3
Alonso, M.4
-
21
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., and Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403 (2000) 98-103
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
22
-
-
21044449225
-
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
-
Noble W., Planel E., Zehr C., Olm V., Meyerson J., Suleman F., Gaynor K., Wang L., LaFrancois J., Feinstein B., Burns M., Krishnamurthy P., Wen Y., Bhat R., Lewis J., Dickson D., and Duff K. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 6990-6995
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 6990-6995
-
-
Noble, W.1
Planel, E.2
Zehr, C.3
Olm, V.4
Meyerson, J.5
Suleman, F.6
Gaynor, K.7
Wang, L.8
LaFrancois, J.9
Feinstein, B.10
Burns, M.11
Krishnamurthy, P.12
Wen, Y.13
Bhat, R.14
Lewis, J.15
Dickson, D.16
Duff, K.17
-
23
-
-
0036136897
-
Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway
-
Pap M., and Cooper G.M. Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway. Mol. Cell. Biol. 22 (2002) 578-586
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 578-586
-
-
Pap, M.1
Cooper, G.M.2
-
24
-
-
0036827161
-
Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease
-
Robinson S.R., and Bishop G.M. Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease. Neurobiol. Aging 23 (2002) 1051-1072
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 1051-1072
-
-
Robinson, S.R.1
Bishop, G.M.2
-
25
-
-
33847214486
-
Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation
-
Rockenstein E., Torrance M., Adame A., Mante M., Bar-on P., Rose J.B., Crews L., and Masliah E. Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation. J. Neurosci. 27 (2007) 1981-1991
-
(2007)
J. Neurosci.
, vol.27
, pp. 1981-1991
-
-
Rockenstein, E.1
Torrance, M.2
Adame, A.3
Mante, M.4
Bar-on, P.5
Rose, J.B.6
Crews, L.7
Masliah, E.8
-
26
-
-
0032212348
-
An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts
-
Ryves W.J., Fryer L., Dale T., and Harwood A.J. An assay for glycogen synthase kinase 3 (GSK-3) for use in crude cell extracts. Anal. Biochem. 264 (1998) 124-127
-
(1998)
Anal. Biochem.
, vol.264
, pp. 124-127
-
-
Ryves, W.J.1
Fryer, L.2
Dale, T.3
Harwood, A.J.4
-
27
-
-
0347115864
-
NADPH oxidase contributes directly to oxidative stress and apoptosis in nerve growth factor-deprived sympathetic neurons
-
Tammariello S.P., Quinn M.T., and Estus S. NADPH oxidase contributes directly to oxidative stress and apoptosis in nerve growth factor-deprived sympathetic neurons. J. Neurosci. 20 (2000) 1-5
-
(2000)
J. Neurosci.
, vol.20
, pp. 1-5
-
-
Tammariello, S.P.1
Quinn, M.T.2
Estus, S.3
-
28
-
-
4544304149
-
Glycogen synthase kinase-3 inhibitors prevent caspase-dependent apoptosis induced by ethanol in cultured rat cortical neurons
-
Takadera T., and Ohyashiki T. Glycogen synthase kinase-3 inhibitors prevent caspase-dependent apoptosis induced by ethanol in cultured rat cortical neurons. Eur. J. Pharmacol. 499 (2004) 239-245
-
(2004)
Eur. J. Pharmacol.
, vol.499
, pp. 239-245
-
-
Takadera, T.1
Ohyashiki, T.2
-
29
-
-
0030044463
-
Exposure of rat hippocampal neurons to amyloid h peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3h
-
Takashima A., Noguchi K., Michel G., Mercken M., Hoshi M., Ishiguro K., and Imahori K. Exposure of rat hippocampal neurons to amyloid h peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3h. Neurosci. Lett. 203 (1996) 33-36
-
(1996)
Neurosci. Lett.
, vol.203
, pp. 33-36
-
-
Takashima, A.1
Noguchi, K.2
Michel, G.3
Mercken, M.4
Hoshi, M.5
Ishiguro, K.6
Imahori, K.7
-
30
-
-
0034513218
-
"Fatal attractions" of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders
-
Trojanowski J.Q., and Lee V.M. "Fatal attractions" of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders. Ann. N. Y. Acad. Sci. 924 (2000) 62-67
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.924
, pp. 62-67
-
-
Trojanowski, J.Q.1
Lee, V.M.2
-
31
-
-
26844488803
-
Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): a radiolabelled glycogen synthase kinase-3beta specific inhibitor for PET studies
-
Vasdev N., Natesan S., Galineau L., Garcia A., Stableford W.T., McCormick P., Seeman P., Houle S., and Wilson A.A. Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): a radiolabelled glycogen synthase kinase-3beta specific inhibitor for PET studies. Bioorg. Med. Chem. Lett. 15 (2005) 5270-5273
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 5270-5273
-
-
Vasdev, N.1
Natesan, S.2
Galineau, L.3
Garcia, A.4
Stableford, W.T.5
McCormick, P.6
Seeman, P.7
Houle, S.8
Wilson, A.A.9
-
32
-
-
4043088415
-
The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught?
-
Verdile G., Fuller S., Atwood C.S., Laws S.M., Gandy S.E., and Martins R.N. The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught?. Pharmacol. Res. 50 (2004) 397-409
-
(2004)
Pharmacol. Res.
, vol.50
, pp. 397-409
-
-
Verdile, G.1
Fuller, S.2
Atwood, C.S.3
Laws, S.M.4
Gandy, S.E.5
Martins, R.N.6
-
33
-
-
0442274617
-
Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53
-
Watcharasit P., Bijur G.N., Song L., Zhu J., Chen X., and Jope R.S. Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J. Biol. Chem. 278 (2003) 48872-48879
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48872-48879
-
-
Watcharasit, P.1
Bijur, G.N.2
Song, L.3
Zhu, J.4
Chen, X.5
Jope, R.S.6
-
34
-
-
0032429784
-
Temporal relations among beta-peptide-induced free-radical oxidative stress, neuronal toxicity, and neuronal defensive responses
-
Yatin S.M., Aksenova M., Aksenov M., Markesbery W.R., Aulick T., and Butterfield D.A. Temporal relations among beta-peptide-induced free-radical oxidative stress, neuronal toxicity, and neuronal defensive responses. J. Mol. Neurosci. 11 (1998) 183-197
-
(1998)
J. Mol. Neurosci.
, vol.11
, pp. 183-197
-
-
Yatin, S.M.1
Aksenova, M.2
Aksenov, M.3
Markesbery, W.R.4
Aulick, T.5
Butterfield, D.A.6
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