Effects of somatic mutations on CDR loop flexibility during affinity maturation

Proteins: Structure, Function and Bioinformatics

Volumn 79, Issue 3, 2011, Pages 821-829

  Wong, Sergio E ^a   Sellers, Ben D ^a   Jacobson, Matthew P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

28B4; 48G7; 4G12; Antibody maturation; AZ28; CDR H3; Flexibility; Molecular dynamics; Somatic mutations

Indexed keywords

28B4 ANTIBODY; 48G7 ANTIBODY; ANTIBODY; AZ28 ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY STRUCTURE; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; HEAVY CHAIN; LIGHT CHAIN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN PROCESSING; SOMATIC MUTATION;

CLUSTER ANALYSIS; COMPLEMENTARITY DETERMINING REGIONS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION;

EID: 79551493763     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22920     Document Type: Article

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