The interplay between binding energy and catalysis in the evolution of a catalytic antibody

Nature

Volumn 389, Issue 6648, 1997, Pages 271-275

  Ulrich, Helle D ^a   Mundorff, Emily ^a   Santarsiero, Bernard D ^a   Driggers, Edward M ^a   Stevens, Raymond C ^a   Sehulta, Peter G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC ANTIBODY;

ANTIGEN BINDING; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENERGY TRANSFER; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION;

ALDEHYDES; ALKADIENES; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, CATALYTIC; ANTIBODIES, MONOCLONAL; CATALYSIS; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ELECTROCHEMISTRY; EVOLUTION, MOLECULAR; GERM-LINE MUTATION; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION;

OXY;

EID: 0030930805     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/38470     Document Type: Article

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