Changes in structure and dynamics of the Fv fragment of a catalytic antibody upon binding of inhibitor

Protein Science

Volumn 12, Issue 7, 2003, Pages 1386-1394

  Kroon, Gerard J A ^a   Mo, Huaping ^a   Martinez Yamout, Maria A ^a   Dyson, H Jane ^a   Wright, Peter E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Anisotropy; Catalysis; Model free analysis; NMR; Relaxation measurements

Indexed keywords

4 NITROPHENOL; CATALYTIC ANTIBODY; LIGAND; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY NPN43C9; UNCLASSIFIED DRUG;

ANISOTROPY; ANTIGEN BINDING; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; DIFFUSION; IMMUNOGLOBULIN VARIABLE REGION; MEASUREMENT; MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

AMIDES; ANISOTROPY; ANTIBODIES, CATALYTIC; BINDING SITES, ANTIBODY; CATALYSIS; DIFFUSION; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NITROPHENOLS; PROTEIN CONFORMATION;

EID: 0037634024     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0243303     Document Type: Article

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