메뉴 건너뛰기




Volumn 169, Issue , 2011, Pages 73-93

Renal interstitial fibrosis: A critical evaluation of the origin of myofibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; CELL DIFFERENTIATION; CHRONIC DISEASE; DISEASE MODEL; EPITHELIUM CELL; FIBROSIS; GUINEA PIG; HUMAN; KIDNEY; KIDNEY DISEASE; MESODERM; MOUSE; MYOFIBROBLAST; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT; RAT;

EID: 79551479332     PISSN: 03025144     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000313946     Document Type: Article
Times cited : (92)

References (230)
  • 1
    • 0038479047 scopus 로고    scopus 로고
    • Mechanisms of renal fibrogenesis
    • Neilson EG Couser WG eds Philadelphia, Lippincott Williams & Wilkins
    • Strutz F, Muller GA: Mechanisms of renal fibrogenesis; in Neilson EG, Couser WG (eds): Immunologic Renal Diseases. Philadelphia, Lippincott Williams & Wilkins, 2001, pp 73- 101.
    • (2001) Immunologic Renal Diseases , pp. 73-101
    • Strutz, F.1    Muller, G.A.2
  • 2
    • 0028961697 scopus 로고
    • Aging-associated changes in renal extracellular matrix
    • Abrass CK, Adcox MJ, Raugi GJ: Aging- associated chanes in renal extracellular matrix. Am J Pathol 1995;146:742-752.
    • (1995) Am. J. Pathol. , vol.146 , pp. 742-752
    • Abrass, C.K.1    Adcox, M.J.2    Raugi, G.J.3
  • 4
    • 0031952093 scopus 로고    scopus 로고
    • Tubulointerstitial disease in aging: Evidence for underlying peritubular capillary damage a potential role for renal ischemia
    • Thomas SE, Anderson S, Gordon KL, Oyama TT, Shankland SJ, Johnson RJ: Tubulointerstitial disease in aging: evidence for underlying peritubular capillary damage, a potential role for renal ischemia. J Am Soc Nephrol 1998;9:231-242.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 231-242
    • Thomas, S.E.1    Anderson, S.2    Gordon, K.L.3    Oyama, T.T.4    Shankland, S.J.5    Johnson, R.J.6
  • 5
    • 0024455538 scopus 로고
    • Interstitial nephritis induced by protein-overload proteinuria
    • Eddy AA: Interstitial nephritis induced by protein- overload proteinuria. Am J Pathol 1989;135:719-733.
    • (1989) Am. J. Pathol. , vol.135 , pp. 719-733
    • Eddy, A.A.1
  • 6
    • 0015900440 scopus 로고
    • Induction of smooth muscle characteristics in renal interstitial fibroblasts during obstructive nephropathy
    • Nagle RB, Kneiser MR, Bulger RE, Benditt EP: Induction of smooth muscle characteristics in renal interstitial fibroblasts during obstructive nephropathy. Lab Invest 1973;29: 422-427.
    • (1973) Lab Invest. , vol.29 , pp. 422-427
    • Nagle, R.B.1    Kneiser, M.R.2    Bulger, R.E.3    Benditt, E.P.4
  • 7
    • 67349203391 scopus 로고    scopus 로고
    • Thornhill BA: Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy
    • Chevalier RL, Forbes MS, Thornhill BA: Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy. Kidney Int 2009;75:1145-1152.
    • (2009) Kidney Int , vol.75 , pp. 1145-1152
    • Chevalier, R.L.1    Forbes, M.S.2
  • 8
    • 0030936207 scopus 로고    scopus 로고
    • Medullary injury in the ageing rat kidney: Functionalmorphometric correlations
    • Greenfeld Z, Stillman IE, Brezis M, Rosen S: Medullary injury in the ageing rat kidney: functionalmorphometric correlations. Eur J Clin Invest 1997;27:346-351.
    • (1997) Eur. J. Clin. Invest. , vol.27 , pp. 346-351
    • Greenfeld, Z.1    Stillman, I.E.2    Brezis, M.3    Rosen, S.4
  • 9
    • 0024519366 scopus 로고
    • Age-related nephropathy and proteinuria in rats with intact kidneys expo sed to diets with different protein content
    • Bertani T, Zoja C, Abbate M, Rossini M, Remuzzi G: Age- related nephropathy and proteinuria in rats with intact kidneys expo sed to diets with different protein content. Lab Invest 1989;60:196-204.
    • (1989) Lab Invest. , vol.60 , pp. 196-204
    • Bertani, T.1    Zoja, C.2    Abbate, M.3    Rossini, M.4    Remuzzi, G.5
  • 10
    • 0022512744 scopus 로고
    • Age-dependent glomerulosclerosis and proteinuria occurring in rats of the milan normotensive strain and not in rats of the milan hypertensive strain
    • Brandis A, Bianchi G, Reale E, Helmchen U, Kuhn K: Age- dependent glomerulosclerosis and proteinuria occurring in rats of the Milan normotensive strain and not in rats of the Milan hypertensive strain. Lab Invest 1986;55:234-243.
    • (1986) Lab Invest. , vol.55 , pp. 234-243
    • Brandis, A.1    Bianchi, G.2    Reale, E.3    Helmchen, U.4    Kuhn, K.5
  • 11
    • 0344236407 scopus 로고    scopus 로고
    • A major gene locus links early onset albuminuria with renal interstitial fibrosis in the MWF rat with polygenetic albuminuria
    • Schulz A, Standke D, Kovacevic L, Mostler M, Kossmehl P, Stoll M, Kreutz R: A major gene locus links early onset albuminuria with renal interstitial fibrosis in the MWF rat with polygenetic albuminuria. J Am Soc Nephrol 2003;14:3081-3089.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 3081-3089
    • Schulz, A.1    Standke, D.2    Kovacevic, L.3    Mostler, M.4    Kossmehl, P.5    Stoll, M.6    Kreutz, R.7
  • 12
    • 34347375050 scopus 로고    scopus 로고
    • Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors
    • Sugimoto H, Grahovac G, Zeisberg M, Kalluri R: Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein- 7 and advanced glycation end product inhibitors. Diabetes 2007;56: 1825-1833.
    • (2007) Diabetes , vol.56 , pp. 1825-1833
    • Sugimoto, H.1    Grahovac, G.2    Zeisberg, M.3    Kalluri, R.4
  • 13
    • 34548395919 scopus 로고    scopus 로고
    • Tubular atrophy interstitial fibrosis and inflammation in type 2 diabetic db/db mice an accelerated model of advanced diabetic nephropathy
    • Ninichuk V, Kulkarni O, Clauss S, Anders HJ: Tubular atrophy, interstitial fibrosis, and inflammation in type 2 diabetic db/db mice. An accelerated model of advanced diabetic nephropathy. Eur J Med Res 2007;12:351-355.
    • (2007) Eur. J. Med. Res. , vol.12 , pp. 351-355
    • Ninichuk, V.1    Kulkarni, O.2    Clauss, S.3    Anders, H.J.4
  • 15
    • 0037378409 scopus 로고    scopus 로고
    • L-arginine supplementation accelerates renal fibrosis and shortens life span in experimental lupus nephritis
    • Peters H, Border WA, Ruckert M, Kramer S, Neumayer HH, and Noble NA: L- arginine supplementation accelerates renal fibrosis and shortens life span in experimental lupus nephritis. Kidney Int 2003;63:1382-1392.
    • (2003) Kidney Int , vol.63 , pp. 1382-1392
    • Peters, H.1    Border, W.A.2    Ruckert, M.3    Kramer, S.4    Neumayer, H.H.5    Noble, N.A.6
  • 17
    • 0028007558 scopus 로고
    • Tubular basement membrane changes during induction and regression of drug-induced polycystic kidney disease
    • Carone FA, Butkowski RJ, Nakamura S, Polenakovic M, and Kanwar YS: Tubular basement membrane changes during induction and regression of drug- induced polycystic kidney disease. Kidney Int 1994;46: 1368-1374.
    • (1994) Kidney Int , vol.46 , pp. 1368-1374
    • Carone, F.A.1    Butkowski, R.J.2    Nakamura, S.3    Polenakovic, M.4    Kanwar, Y.S.5
  • 18
    • 0024590418 scopus 로고
    • Food restriction retards body growth and prevents end-stage renal pathology in remnant kidneys of rats regardless of protein intake
    • Tapp DC, Wortham WG, Addison JF, Hammonds DN, Barnes JL, Venkatachalam MA: Food restriction retards body growth and prevents end- stage renal pathology in remnant kidneys of rats regardless of protein intake. Lab Invest 1989;60:184-195.
    • (1989) Lab Invest. , vol.60 , pp. 184-195
    • Tapp, D.C.1    Wortham, W.G.2    Addison, J.F.3    Hammonds, D.N.4    Barnes, J.L.5    Venkatachalam, M.A.6
  • 19
  • 20
    • 0022412410 scopus 로고
    • Rapidly progressive renal deterioration in partially nephrectomized rats with experimental membranous nephropathy
    • Okuda S, Oh Y, Tsuruda H, Onoyama K, Fujimi S, Omae T, Fujishima M: Rapidly progressive renal deterioration in partially nephrectomized rats with experimental membranous nephropathy. Nephron 1985;41:359-364.
    • (1985) Nephron. , vol.41 , pp. 359-364
    • Okuda, S.1    Oh, Y.2    Tsuruda, H.3    Onoyama, K.4    Fujimi, S.5    Omae, T.6    Fujishima, M.7
  • 21
    • 15444362469 scopus 로고    scopus 로고
    • Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES
    • Gong R, Rifai A, Tolbert EM, Biswas P, Centracchio JN, Dworkin LD: Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein- 1 and RANTES. J Am Soc Nephrol 2004;15:2868-2881.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2868-2881
    • Gong, R.1    Rifai, A.2    Tolbert, E.M.3    Biswas, P.4    Centracchio, J.N.5    Dworkin, L.D.6
  • 23
    • 0030816190 scopus 로고    scopus 로고
    • Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/ reperfusion injury of a single kidney
    • Azuma H, Nadeau K, Takada M, Mackenzie HS, Tilney NL: Cellular and molecular predictors of chronic renal dysfunction after initial ischemia/ reperfusion injury of a single kidney. Transplantation 1997;64:190-197.
    • (1997) Transplantation , vol.64 , pp. 190-197
    • Azuma, H.1    Nadeau, K.2    Takada, M.3    Mackenzie, H.S.4    Tilney, N.L.5
  • 24
    • 0032878531 scopus 로고    scopus 로고
    • A rat model of progressive chronic renal failure produced by microembolism
    • Kimura M, Suzuki T, Hishida A: A rat model of progressive chronic renal failure produced by microembolism. Am J Pathol 1999;155:1371-1380.
    • (1999) Am. J. Pathol. , vol.155 , pp. 1371-1380
    • Kimura, M.1    Suzuki, T.2    Hishida, A.3
  • 25
    • 0031948169 scopus 로고    scopus 로고
    • Evolution of tubulointerstitial fibrosis in experimental renal infection and scarring
    • Hewitson TD, Darby IA, Bisucci T, Jones CL, Becker GJ: Evolution of tubulointerstitial fibrosis in experimental renal infection and scarring. J Am Soc Nephrol 1998;9:6326-6342.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 6326-6342
    • Hewitson, T.D.1    Darby, I.A.2    Bisucci, T.3    Jones, C.L.4    Becker, G.J.5
  • 26
    • 0025860691 scopus 로고
    • Tubulointerstitial nephritis during the heterologous phase of nephrotoxic serum nephritis
    • Eddy AA: Tubulointerstitial nephritis during the heterologous phase of nephrotoxic serum nephritis. Nephron 1991:59:304-313.
    • (1991) Nephron. , vol.59 , pp. 304-313
    • Eddy, A.A.1
  • 27
    • 0026502594 scopus 로고
    • The contribution of antibody-mediated cytotoxicity and immune-complex formation to tubulointerstitial disease in passive heymann nephritis
    • Eddy AA, Ho GC, Thorner PS: The contribution of antibody- mediated cytotoxicity and immune- complex formation to tubulointerstitial disease in passive Heymann nephritis. Clin Immunol Immunopathol 1992;62:42-55.
    • (1992) Clin. Immunol. Immunopathol. , vol.62 , pp. 42-55
    • Eddy, A.A.1    Ho, G.C.2    Thorner, P.S.3
  • 28
    • 0023873333 scopus 로고
    • Acute tubulointerstitial nephritis associated with aminonucleoside nephrosis
    • Eddy AA, Michael AF: Acute tubulointerstitial nephritis associated with aminonucleoside nephrosis. Kidney Int 1988;33:14-23.
    • (1988) Kidney Int , vol.33 , pp. 14-23
    • Eddy, A.A.1    Michael, A.F.2
  • 29
    • 0023637202 scopus 로고
    • The enhancement of aminonucleoside nephrosis by the coadministration of protamine
    • Saito T, Sumithran E, Glasgow EF,Atkins RC: The enhancement of aminonucleoside nephrosis by the coadministration of protamine. Kidney Int 1987;32:691-699.
    • (1987) Kidney Int , vol.32 , pp. 691-699
    • Saito, T.1    Sumithran, E.2    Glasgow, E.F.3    Atkins, R.C.4
  • 30
    • 0026090926 scopus 로고
    • Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis
    • Jones CL, Buch S, Post M, McCulloch L, Liu E, Eddy AA: Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis. Kidney Int 1991;40:1020-1031.
    • (1991) Kidney Int , vol.40 , pp. 1020-1031
    • Jones, C.L.1    Buch, S.2    Post, M.3    McCulloch, L.4    Liu, E.5    Eddy, A.A.6
  • 33
    • 0022441229 scopus 로고
    • Tubulo-interstitial lesions mediate renal damage in adriamycin glomerulopathy
    • Bertani T, Cutillo F, Zoja C, Broggini M, Remuzzi G: Tubulo- interstitial lesions mediate renal damage in adriamycin glomerulopathy. Kidney Int 1986;30:488-496.
    • (1986) Kidney Int , vol.30 , pp. 488-496
    • Bertani, T.1    Cutillo, F.2    Zoja, C.3    Broggini, M.4    Remuzzi, G.5
  • 35
    • 0028280073 scopus 로고
    • Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis
    • Yamamoto T, Noble NA, Miller DE, Border WA: Sustained expression of TGF- beta 1 underlies development of progressive kidney fibrosis. Kidney Int 1994;45:916-927.
    • (1994) Kidney Int , vol.45 , pp. 916-927
    • Yamamoto, T.1    Noble, N.A.2    Miller, D.E.3    Border, W.A.4
  • 37
    • 0032989096 scopus 로고    scopus 로고
    • L-Arginine supplementation increases mesangial cell injury and subsequent tissue fibrosis in experimental glomerulonephritis
    • Peters H, Border WA, Noble NA: L- Arginine supplementation increases mesangial cell injury and subsequent tissue fibrosis in experimental glomerulonephritis. Kidney Int 1999;55:2264-2273.
    • (1999) Kidney Int , vol.55 , pp. 2264-2273
    • Peters, H.1    Border, W.A.2    Noble, N.A.3
  • 40
    • 27544515448 scopus 로고    scopus 로고
    • Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis
    • Faulkner JL, Szcykalski LM, Springer F, Barnes JL: Origin of interstitial fibroblasts in an accelerated model of angiotensin II- induced renal fibrosis. Am J Pathol 2005;167:1193-1205.
    • (2005) Am. J. Pathol. , vol.167 , pp. 1193-1205
    • Faulkner, J.L.1    Szcykalski, L.M.2    Springer, F.3    Barnes, J.L.4
  • 41
    • 0019859126 scopus 로고
    • Renal injury and proteinuria in female spontaneously hypertensive rats
    • Feld LG, Brentjens JR, Van Liew JB: Renal injury and proteinuria in female spontaneously hypertensive rats. Renal Physiol 1981;4:46-56.
    • (1981) Renal. Physiol. , vol.4 , pp. 46-56
    • Feld, L.G.1    Brentjens, J.R.2    Van Liew, J.B.3
  • 42
    • 0030928848 scopus 로고    scopus 로고
    • Effects of early and late antihypertensive treatment on extracellular matrix proteins and mononuclear cells in uninephrectomized SHR
    • Geiger H, Fierlbeck W, Mai M, Ruchti H, Schonfeld V, Dammrich J, Hugo C, Neumayer HH: Effects of early and late antihypertensive treatment on extracellular matrix proteins and mononuclear cells in uninephrectomized SHR. Kidney Int 1997;51:750-761.
    • (1997) Kidney Int , vol.51 , pp. 750-761
    • Geiger, H.1    Fierlbeck, W.2    Mai, M.3    Ruchti, H.4    Schonfeld, V.5    Dammrich, J.6    Hugo, C.7    Neumayer, H.H.8
  • 45
    • 8244264903 scopus 로고
    • Renin- angiotensin system in stroke-prone spontaneously hypertensive rats
    • Shibota M, Nagaoka A, Shino A, Fujita T: Renin- angiotensin system in stroke- prone spontaneously hypertensive rats. Am J Physiol 1979;236:H409-H416.
    • (1979) Am. J. Physiol. , vol.236
    • Shibota, M.1    Nagaoka, A.2    Shino, A.3    Fujita, T.4
  • 46
    • 0021858418 scopus 로고
    • Development and characteristics of inbred strains of dahl salt sen sitive and salt-resistant rats
    • Rapp JP, Dene H: Development and characteristics of inbred strains of Dahl salt sen sitive and salt- resistant rats. Hypertension 1985;7:340-349.
    • (1985) Hypertension , vol.7 , pp. 340-349
    • Rapp, J.P.1    Dene, H.2
  • 50
    • 0033667322 scopus 로고    scopus 로고
    • Renal fibrosis in mice treated with human recombinant transforming growth factor-beta2
    • Ledbetter S, Kurtzberg L, Doyle S, Pratt BM: Renal fibrosis in mice treated with human recombinant transforming growth factor- beta2. Kidney Int 2000;58:2367-2376.
    • (2000) Kidney Int , vol.58 , pp. 2367-2376
    • Ledbetter, S.1    Kurtzberg, L.2    Doyle, S.3    Pratt, B.M.4
  • 52
    • 0024378832 scopus 로고
    • Non-metallothioneinbound cadmium in the pathogenesis of cadmium nephrotoxicity in the rat
    • Goyer RA, Miller CR, Zhu SY, and Victery W: Non- metallothioneinbound cadmium in the pathogenesis of cadmium nephrotoxicity in the rat.Toxicol Appl Pharmacol 1989;101: 232-244.
    • (1989) Toxicol. Appl. Pharmacol. , vol.101 , pp. 232-244
    • Goyer, R.A.1    Miller, C.R.2    Zhu, S.Y.3    Victery, W.4
  • 55
    • 51849182647 scopus 로고
    • The long-term effects of uranyl nitrate on the structure and function of the rat kidney
    • Haley DP, Bulger RE, Dobyan DC: The long- term effects of uranyl nitrate on the structure and function of the rat kidney. Virchows Arch B Cell Pathol 1982;41:181-192.
    • (1982) Virchows. Arch.. B Cell Pathol. , vol.41 , pp. 181-192
    • Haley, D.P.1    Bulger, R.E.2    Dobyan, D.C.3
  • 56
    • 0019165111 scopus 로고
    • Nephrotoxicity of mild analgesics in the gunn strain of rat
    • Axelsen RA: Nephrotoxicity of mild analgesics in the Gunn strain of rat. Br J Clin Pharmacol 1980;10(Suppl 2):309S- 312S.
    • (1980) Br. J. Clin. Pharmacol. , vol.10 , Issue.2
    • Axelsen, R.A.1
  • 57
    • 0023215291 scopus 로고
    • Renal injury induced by long-term administration of cyclosporin A to rats
    • Bertani T, Perico N, Abbate M, Battaglia C, Remuzzi G: Renal injury induced by long- term administration of cyclosporin A to rats. Am J Pathol 1987;127:569-579.
    • (1987) Am. J. Pathol. , vol.127 , pp. 569-579
    • Bertani, T.1    Perico, N.2    Abbate, M.3    Battaglia, C.4    Remuzzi, G.5
  • 61
    • 0031869430 scopus 로고    scopus 로고
    • Interstitial fibrosis in hypercholesterolemic rats: Role of oxidation matrix syn thesis proteolytic cascades
    • Eddy AA: Interstitial fibrosis in hypercholesterolemic rats: role of oxidation, matrix synthesis, proteolytic cascades. Kidney Int 1998;53:1182-1189.
    • (1998) Kidney Int , vol.53 , pp. 1182-1189
    • Eddy, A.A.1
  • 62
    • 0018239167 scopus 로고
    • Healed experimental renal papillary necrosis and cortical scarring in the rat from 2-bromoethylamine hydrobromide
    • Axelsen RA: Healed experimental renal papillary necrosis and cortical scarring in the rat from 2- bromoethylamine hydrobromide. Virchows Arch B Pathol Anat Histol 1978;381:63-77.
    • (1978) Virchows. Arch. B Pathol. Anat. Histol. , vol.381 , pp. 63-77
    • Axelsen, R.A.1
  • 65
    • 0026502928 scopus 로고
    • Transgenic rats carrying the mouse renin gene - Morphological characterization of a low-renin hypertension model
    • Bachmann S, Peters J, Engler E, Ganten D, Mullins J: Transgenic rats carrying the mouse renin gene - morphological characterization of a low- renin hypertension model. Kidney Int 1992;41:24-36.
    • (1992) Kidney Int , vol.41 , pp. 24-36
    • Bachmann, S.1    Peters, J.2    Engler, E.3    Ganten, D.4    Mullins, J.5
  • 66
    • 0031823522 scopus 로고    scopus 로고
    • A new model of diabetic nephropathy with progressive renal impairment in the transgenic mRen-2 27 rat TGR
    • Kelly DJ, Wilkinson- Berka JL, Allen TJ, Cooper ME, Skinner SL: A new model of diabetic nephropathy with progressive renal impairment in the transgenic (mRen- 2)27 rat (TGR). Kidney Int 1998;54:343-352.
    • (1998) Kidney Int , vol.54 , pp. 343-352
    • Kelly, D.J.1    Wilkinson-Berka, J.L.2    Allen, T.J.3    Cooper, M.E.4    Skinner, S.L.5
  • 68
    • 0030457613 scopus 로고    scopus 로고
    • Molecular and functional defects in kidneys of mice lacking collagen alpha 3 IV: Implications for alport syndrome
    • Miner JH, Sanes JR: Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome. J Cell Biol 1996;135:1403-1413.
    • (1996) J. Cell. Biol. , vol.135 , pp. 1403-1413
    • Miner, J.H.1    Sanes, J.R.2
  • 71
    • 0038364209 scopus 로고    scopus 로고
    • Localisation and phenotypical characterisation of collagen-producing cells in TGF-beta 1-induced renal interstitial fibrosis
    • Chai Q, Krag S, Chai S, Ledet T, Wogensen L: Localisation and phenotypical characterisation of collagen- producing cells in TGF- beta 1- induced renal interstitial fibrosis. Histochem Cell Biol 2003;119:267-280.
    • (2003) Histochem. Cell Biol. , vol.119 , pp. 267-280
    • Chai, Q.1    Krag, S.2    Chai, S.3    Ledet, T.4    Wogensen, L.5
  • 73
    • 17244362446 scopus 로고    scopus 로고
    • SAMP1/Sku as a murine model for tubulointerstitial nephritis: A study using unilateral ureteral obstruction
    • Yabuki A, Maeda M, Matsumoto M, Kami mura R, Masuyama T, Suzuki S: SAMP1/Sku as a murine model for tubulointerstitial nephritis: a study using unilateral ureteral obstruction. Exp Animals 2005;54:53-60.
    • (2005) Exp. Animals. , vol.54 , pp. 53-60
    • Yabuki, A.1    Maeda, M.2    Matsumoto, M.3    Kami Mura, R.4    Masuyama, T.5    Suzuki, S.6
  • 74
    • 33845981877 scopus 로고    scopus 로고
    • Smooth muscle alpha-actin deficiency in myofibroblasts leads to enhanced renal tissue fibrosis
    • Takeji M, Moriyama T, Oseto S,Kawada N, Hori M, Imai E, Miwa T: Smooth muscle alpha- actin deficiency in myofibroblasts leads to enhanced renal tissue fibrosis. J Biol Chem 2006;281:40193-40200.
    • (2006) J. Biol. Chem. , vol.281 , pp. 40193-40200
    • Takeji, M.1    Moriyama, T.2    Oseto, S.3    Kawada, N.4    Hori, M.5    Imai, E.6    Miwa, T.7
  • 79
    • 33751582928 scopus 로고    scopus 로고
    • Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney
    • Boutet A, De Frutos CA, Maxwell PH, Mayol MJ, Romero J, Nieto MA: Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney. EMBO J 2006;25:5603-5613.
    • (2006) EMBO J. , vol.25 , pp. 5603-5613
    • Boutet, A.1    De Frutos, C.A.2    Maxwell, P.H.3    Mayol, M.J.4    Romero, J.5    Nieto, M.A.6
  • 82
    • 33644779814 scopus 로고    scopus 로고
    • A severe diabetic nephropathy model with early development of nodule-like lesions induced by megsin overexpression in RAGE/ iNOS transgenic mice
    • Inagi R, Yamamoto Y, Nangaku M, Usuda N, Okamato H, Kurokawa K, van Ypersele de SC, Yamamoto H, Miyata T: A severe diabetic nephropathy model with early development of nodule- like lesions induced by megsin overexpression in RAGE/ iNOS transgenic mice. Diabetes 2006;55:356-366.
    • (2006) Diabetes , vol.55 , pp. 356-366
    • Inagi, R.1    Yamamoto, Y.2    Nangaku, M.3    Usuda, N.4    Okamato, H.5    Kurokawa, K.6    Van Ypersele De, S.C.7    Yamamoto, H.8    Miyata, T.9
  • 83
    • 34447265300 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor in kidney leads to progressive impairment of glomerular functions
    • Liu E, Morimoto M, Kitajima S, Koike T, Yu Y, Shiiki H, Nagata M, Watanabe T, Fan J: Increased expression of vascular endothelial growth factor in kidney leads to progressive impairment of glomerular functions. J Am Soc Nephrol 2007;18:2094-2104.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2094-2104
    • Liu, E.1    Morimoto, M.2    Kitajima, S.3    Koike, T.4    Yu, Y.5    Shiiki, H.6    Nagata, M.7    Watanabe, T.8    Fan, J.9
  • 84
    • 33845576431 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 and basement membrane integrity: A unifying mechanism for progressive renal injury
    • Cheng S, Pollock AS, Mahimkar R, Olson JL, Lovett DH: Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury. FASEB J 2006;20:1898-1900.
    • (2006) FASEB J. , vol.20 , pp. 1898-1900
    • Cheng, S.1    Pollock, A.S.2    Mahimkar, R.3    Olson, J.L.4    Lovett, D.H.5
  • 85
    • 54749083116 scopus 로고    scopus 로고
    • Heme oxygenase-1 deficiency promotes epithelial-mesenchymal transition and renal fibrosis
    • Kie JH, Kapturczak MH, Traylor A, Agarwal A, Hill- Kapturczak N: Heme oxygenase- 1 deficiency promotes epithelial- mesenchymal transition and renal fibrosis. J Am Soc Nephrol 2008;19:1681-1691.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1681-1691
    • Kie, J.H.1    Kapturczak, M.H.2    Traylor, A.3    Agarwal, A.4    Hill-Kapturczak, N.5
  • 89
    • 52649137487 scopus 로고    scopus 로고
    • R2: Identification of renal potential progenitor/stem cells that participate in the renal regeneration processes of kidney allograft fibrosis
    • Bao J, Tu Z, Sun H, Luo G, Yang L, Song J, Qin M, Shi Y, Bu H, Li Y: R2: identification of renal potential progenitor/stem cells that participate in the renal regeneration processes of kidney allograft fibrosis. Nephrology 2008;13:500-507.
    • (2008) Nephrology , vol.13 , pp. 500-507
    • Bao, J.1    Tu, Z.2    Sun, H.3    Luo, G.4    Yang, L.5    Song, J.6    Qin, M.7    Shi, Y.8    Bu, H.9    Li, Y.10
  • 90
    • 33947491882 scopus 로고    scopus 로고
    • Loss of the alpha-isoform of calcineurin is sufficient to induce nephrotoxicity and altered expression of transforming growth factor-beta
    • Gooch JL, Roberts BR, Cobbs SL, Tumlin JA: Loss of the alpha- isoform of calcineurin is sufficient to induce nephrotoxicity and altered expression of transforming growth factor- beta. Transplantation 2007;83: 439-447.
    • (2007) Transplantation , vol.83 , pp. 439-447
    • Gooch, J.L.1    Roberts, B.R.2    Cobbs, S.L.3    Tumlin, J.A.4
  • 92
    • 56549126331 scopus 로고    scopus 로고
    • TNF- alpha deficiency accelerates renal tubular interstitial fibrosis in the late stage of ureteral obstruction
    • Morimoto Y, Gai Z, Tanishima H, Kawakatsu M, Itoh S, Hatamura I, Muragaki Y: TNF- alpha deficiency accelerates renal tubular interstitial fibrosis in the late stage of ureteral obstruction. Exp Mol Pathol 2008;85:207-213.
    • (2008) Exp. Mol. Pathol. , vol.85 , pp. 207-213
    • Morimoto, Y.1    Gai, Z.2    Tanishima, H.3    Kawakatsu, M.4    Itoh, S.5    Hatamura, I.6    Muragaki, Y.7
  • 94
    • 0032040212 scopus 로고    scopus 로고
    • Accelerated fibrosis and collagen deposition develop in the renal interstitium of angiotensin type 2 receptor null mutant mice during ureteral obstruction
    • Ma J, Nishimura H, Fogo A, Kon V, Inagami T, Ichikawa I: Accelerated fibrosis and collagen deposition develop in the renal interstitium of angiotensin type 2 receptor null mutant mice during ureteral obstruction. Kidney Int 1998;53:937-944.
    • (1998) Kidney Int , vol.53 , pp. 937-944
    • Ma, J.1    Nishimura, H.2    Fogo, A.3    Kon, V.4    Inagami, T.5    Ichikawa, I.6
  • 95
    • 0037378488 scopus 로고    scopus 로고
    • Cux- 1 transgenic mice develop glomerulosclerosis and interstitial fibrosis
    • Brantley JG, Sharma M, Alcalay NI, Heuvel GB: Cux- 1 transgenic mice develop glomerulosclerosis and interstitial fibrosis. Kidney Int 2003;63:1240-1248.
    • (2003) Kidney Int , vol.63 , pp. 1240-1248
    • Brantley, J.G.1    Sharma, M.2    Alcalay, N.I.3    Heuvel, G.B.4
  • 96
    • 0033661940 scopus 로고    scopus 로고
    • Postnatal development and progression of renal dysplasia in cyclooxygenase-2 null mice
    • Norwood VF, Morham SG, Smithies O: Postnatal development and progression of renal dysplasia in cyclooxygenase- 2 null mice. Kidney Int 2000;58:2291-2300.
    • (2000) Kidney Int , vol.58 , pp. 2291-2300
    • Norwood, V.F.1    Morham, S.G.2    Smithies, O.3
  • 102
    • 62549118640 scopus 로고    scopus 로고
    • C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse
    • Wenderfer SE, Wang H, Ke B, Wetsel RA, Braun MC: C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse. Mol Immunol 2009;46:1397-1404.
    • (2009) Mol. Immunol. , vol.46 , pp. 1397-1404
    • Wenderfer, S.E.1    Wang, H.2    Ke, B.3    Wetsel, R.A.4    Braun, M.C.5
  • 104
    • 66449119643 scopus 로고    scopus 로고
    • Renal tubulointerstitial fibrosis: Common but never simple
    • Hewitson TD: Renal tubulointerstitial fibrosis: common but never simple. Am J Physiol Renal Physiol 2009;296:F1239-F1244.
    • (2009) Am. J. Physiol. Renal. Physiol. , vol.296
    • Hewitson, T.D.1
  • 106
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • Wynn TA: Cellular and molecular mechanisms of fibrosis. J Pathol 2008;214:199-210.
    • (2008) J. Pathol. , vol.214 , pp. 199-210
    • Wynn, T.A.1
  • 107
    • 0026594064 scopus 로고
    • The biology of the myofibroblast
    • Gabbiani G: The biology of the myofibroblast. Kidney Int 1992;41:530-532.
    • (1992) Kidney Int , vol.41 , pp. 530-532
    • Gabbiani, G.1
  • 109
    • 0028944542 scopus 로고
    • Myofibroblast differentiation during fibrosis
    • Desmouliere A, Gabbiani G: Myofibroblast differentiation during fibrosis. Exp Nephrol 1995;3:134-139.
    • (1995) Exp. Nephrol. , vol.3 , pp. 134-139
    • Desmouliere, A.1    Gabbiani, G.2
  • 110
    • 0024233056 scopus 로고
    • Correlation between the distribution of smooth muscle or non muscle myosins and alpha-smooth muscle actin in normal and pathological soft tissues
    • Benzonana G, Skalli O, Gabbiani G: Correlation between the distribution of smooth muscle or non muscle myosins and alpha- smooth muscle actin in normal and pathological soft tissues. Cell Motil Cytoskeleton 1988;11:260-274.
    • (1988) Cell Motil. Cytoskeleton. , vol.11 , pp. 260-274
    • Benzonana, G.1    Skalli, O.2    Gabbiani, G.3
  • 111
    • 0037899249 scopus 로고    scopus 로고
    • The myofibroblast in wound healing and fibrocontractive diseases
    • Gabbiani G: The myofibroblast in wound healing and fibrocontractive diseases. J Pathol 2003;200:500-503.
    • (2003) J. Pathol. , vol.200 , pp. 500-503
    • Gabbiani, G.1
  • 112
    • 0029948032 scopus 로고    scopus 로고
    • Phenotypic features of cortical interstitial cells potentially important in fibrosis
    • Alpers CE, Pichler R, Johnson RJ: Phenotypic features of cortical interstitial cells potentially important in fibrosis. Kidney Int 1996;54:S28-S31.
    • (1996) Kidney Int , vol.54
    • Alpers, C.E.1    Pichler, R.2    Johnson, R.J.3
  • 113
    • 0028493140 scopus 로고
    • Human renal cortical interstitial cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury
    • Alpers CE, Hudkins KL, Floege J, Johnson RJ: Human renal cortical interstitial cells with some features of smooth muscle cells participate in tubulointerstitial and crescentic glomerular injury. J Am Soc Nephrol 1994;5:201-209.
    • (1994) J Am Soc Nephrol , vol.5 , pp. 201-209
    • Alpers, C.E.1    Hudkins, K.L.2    Floege, J.3    Johnson, R.J.4
  • 114
    • 0027301024 scopus 로고
    • PDGFreceptor localizes to mesangial parietal epithelial and interstitial cells in human and primate kidneys
    • Alpers CE, Seifert RA, Hudkins KL, Johnson RJ, Bowen- Pope DF: PDGFreceptor localizes to mesangial, parietal epithelial, and interstitial cells in human and primate kidneys. Kidney Int 1993;43:286-294.
    • (1993) Kidney Int , vol.43 , pp. 286-294
    • Alpers, C.E.1    Seifert, R.A.2    Hudkins, K.L.3    Johnson, R.J.4    Bowen-Pope, D.F.5
  • 115
    • 0026590662 scopus 로고
    • Enhanced expression of muscle-specific actin in glomerulonephritis
    • Alpers CE, Hudkins KL, Gown AM, Johnson RJ: Enhanced expression of muscle- specific actin in glomerulonephritis. Kidney Int 1992; 41:1134-1142.
    • (1992) Kidney Int , vol.41 , pp. 1134-1142
    • Alpers, C.E.1    Hudkins, K.L.2    Gown, A.M.3    Johnson, R.J.4
  • 116
    • 0033959028 scopus 로고    scopus 로고
    • Role of myofibroblasts during normal tissue repair and excessive scarring: Interest of their assessment in nephropathies
    • Badid C, Mounier N, Costa AM, Desmou liere A: Role of myofibroblasts during normal tissue repair and excessive scarring: interest of their assessment in nephropathies. Histol Histopathol 2000;15: 269-280.
    • (2000) Histol. Histopathol , vol.15 , pp. 269-280
    • Badid, C.1    Mounier, N.2    Costa, A.M.3    Desmouliere, A.4
  • 117
    • 0034922498 scopus 로고    scopus 로고
    • Myofibroblast: A prognostic marker and target cell in progressive renal disease
    • Badid C, Vincent M, Fouque D, Laville M, Desmouliere A: Myofibroblast: a prognostic marker and target cell in progressive renal disease. Ren Fail 2001;23:543-549.
    • (2001) Ren Fail , vol.23 , pp. 543-549
    • Badid, C.1    Vincent, M.2    Fouque, D.3    Laville, M.4    Desmouliere, A.5
  • 122
    • 26444551744 scopus 로고    scopus 로고
    • Role of atrophic changes in proximal tubular cells in the peritubular deposition of type IV collagen in a rat renal ablation model
    • Kimura M, Asano M, Abe K, Miyazaki M, Suzuki T, Hishida A: Role of atrophic changes in proximal tubular cells in the peritubular deposition of type IV collagen in a rat renal ablation model. Nephrol Dial Transplant 2005;20:1559-1565.
    • (2005) Nephrol. Dial. Transplant , vol.20 , pp. 1559-1565
    • Kimura, M.1    Asano, M.2    Abe, K.3    Miyazaki, M.4    Suzuki, T.5    Hishida, A.6
  • 123
    • 57149113728 scopus 로고    scopus 로고
    • Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
    • Lin SL, Kisseleva T, Brenner DA, and Duffield JS: Pericytes and perivascular fibroblasts are the primary source of collagen- producing cells in obstructive fibrosis of the kidney. Am J Pathol 2008;173:1617-1627.
    • (2008) Am. J. Pathol. , vol.173 , pp. 1617-1627
    • Lin, S.L.1    Kisseleva, T.2    Brenner, D.A.3    Duffield, J.S.4
  • 125
    • 0033057938 scopus 로고    scopus 로고
    • Expression of embryonic fibronectin isoform EIIIA parallels alpha-smooth muscle actin in maturing and diseased kidney
    • Barnes VL, Musa J, Mitchell RJ, Barnes JL: Expression of embryonic fibronectin isoform EIIIA parallels alpha- smooth muscle actin in maturing and diseased kidney. J Histochem Cytochem 1999;47:787-798.
    • (1999) J. Histochem. Cytochem. , vol.47 , pp. 787-798
    • Barnes, V.L.1    Musa, J.2    Mitchell, R.J.3    Barnes, J.L.4
  • 128
    • 58849103048 scopus 로고    scopus 로고
    • Targeting renal macrophage accumulation via c- fms kinase reduces tubular apoptosis but fails to modi fy progressive fibrosis in the obstructed rat kidney
    • Ma FY, Liu J, Kitching AR, Manthey CL, Nikolic- Paterson DJ: Targeting renal macrophage accumulation via c- fms kinase reduces tubular apoptosis but fails to modi fy progressive fibrosis in the obstructed rat kidney. Am J Physiol Renal Physiol 2009;296: F177-F185.
    • (2009) Am. J. Physiol. Renal. Physiol. , vol.296
    • Ma, F.Y.1    Liu, J.2    Kitching, A.R.3    Manthey, C.L.4    Nikolic-Paterson, D.J.5
  • 130
    • 0035144846 scopus 로고    scopus 로고
    • Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat
    • Suzuki T, Kimura M, Asano M, Fujigaki Y, Hishida A: Role of atrophic tubules in development of interstitial fibrosis in microembolism- induced renal failure in rat. Am J Pathol 2001;158:75-85.
    • (2001) Am. J. Pathol. , vol.158 , pp. 75-85
    • Suzuki, T.1    Kimura, M.2    Asano, M.3    Fujigaki, Y.4    Hishida, A.5
  • 131
    • 21544440606 scopus 로고    scopus 로고
    • Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys
    • Le Hir M, Hegyi I, Cueni- Loffing D, Loffing J, Kaissling B: Characterization of renal interstitial fibroblast- specific protein 1/S100A4- positive cells in healthy and inflamed rodent kidneys. Histochem Cell Biol 2005;123:335-346.
    • (2005) Histochem. Cell Biol. , vol.123 , pp. 335-346
    • Le Hir, M.1    Hegyi, I.2    Cueni-Loffing, D.3    Loffing, J.4    Kaissling, B.5
  • 132
    • 44449161800 scopus 로고    scopus 로고
    • Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat
    • Picard N, Baum O, Vogetseder A, Kaissling B, Le Hir M: Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat. Histochem Cell Biol 2008;130:141-155.
    • (2008) Histochem. Cell Biol. , vol.130 , pp. 141-155
    • Picard, N.1    Baum, O.2    Vogetseder, A.3    Kaissling, B.4    Le Hir, M.5
  • 133
    • 48749122527 scopus 로고    scopus 로고
    • The renal cortical interstitium: Morphological and functional aspects
    • Kaissling B, Le Hir M: The renal cortical interstitium: morphological and functional aspects. Histochem Cell Biol 2008;130:247-262.
    • (2008) Histochem. Cell Biol. , vol.130 , pp. 247-262
    • Kaissling, B.1    Le Hir, M.2
  • 134
    • 0029074870 scopus 로고
    • Interstitial myofibroblasts in experimental renal infection and scarring
    • Hewitson TD, Wu HL, Becker GJ: Interstitial myofibroblasts in experimental renal infection and scarring. Am J Nephrol 1995;15:411-417.
    • (1995) Am. J. Nephrol. , vol.15 , pp. 411-417
    • Hewitson, T.D.1    Wu, H.L.2    Becker, G.J.3
  • 135
  • 137
    • 0028912035 scopus 로고
    • Interstitial myofibroblasts in IgA glomerulonephritis
    • Hewitson TD, Becker GJ: Interstitial myofibroblasts in IgA glomerulonephritis. Am J Nephrol 1995;15:111-117.
    • (1995) Am. J. Nephrol. , vol.15 , pp. 111-117
    • Hewitson, T.D.1    Becker, G.J.2
  • 139
    • 20844454775 scopus 로고    scopus 로고
    • Activation of ERK in renal fibrosis after unilateral ureteral obstruction: Modulation by antioxidants
    • Pat B, Yang T, Kong C, Watters D, Johnson DW, Gobe G: Activation of ERK in renal fibrosis after unilateral ureteral obstruction: modulation by antioxidants. Kidney Int 2005;67:931-943.
    • (2005) Kidney Int , vol.67 , pp. 931-943
    • Pat, B.1    Yang, T.2    Kong, C.3    Watters, D.4    Johnson, D.W.5    Gobe, G.6
  • 140
    • 0035164489 scopus 로고    scopus 로고
    • Role of apoptosis and Bcl- 2/Bax in the development of tubulointerstitial fibrosis during experimental obstructive nephropathy
    • Zhang G, Oldroyd SD, Huang LH, Yang B, Li Y, Ye R, el Nahas AM: Role of apoptosis and Bcl- 2/Bax in the development of tubulointerstitial fibrosis during experimental obstructive nephropathy. Exp Nephrol 2001;9:71-80.
    • (2001) Exp. Nephrol. , vol.9 , pp. 71-80
    • Zhang, G.1    Oldroyd, S.D.2    Huang, L.H.3    Yang, B.4    Li, Y.5    Ye, R.6    El Nahas, A.M.7
  • 142
    • 20144378863 scopus 로고    scopus 로고
    • Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate-induced acute renal failure in rats
    • Fujigaki Y, Muranaka Y, Sun D, Goto T, Zhou H, Sakakima M, Fukasawa H, Yonemura K, Yamamoto T, Hishida A: Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate- induced acute renal failure in rats. Virchows Arch 2005;446:164-176.
    • (2005) Virchows. Arch. , vol.446 , pp. 164-176
    • Fujigaki, Y.1    Muranaka, Y.2    Sun, D.3    Goto, T.4    Zhou, H.5    Sakakima, M.6    Fukasawa, H.7    Yonemura, K.8    Yamamoto, T.9    Hishida, A.10
  • 145
    • 0025301290 scopus 로고
    • Cellular distribution of transforming growth factor-beta 1 and procollagen types I III and IV transcripts in carbon tetrachloride-induced rat liver fibrosis
    • Nakatsukasa H, Nagy P, Evarts RP, Hsia CC, Marsden E, Thorgeirsson SS: Cellular distribution of transforming growth factor- beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride- induced rat liver fibrosis. J Clin Invest 1990;85:1833-1843.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1833-1843
    • Nakatsukasa, H.1    Nagy, P.2    Evarts, R.P.3    Hsia, C.C.4    Marsden, E.5    Thorgeirsson, S.S.6
  • 147
    • 0027258497 scopus 로고
    • Vascular adventitial cell expression of collagen I messenger ribonucleic acid in anti- glomerular basement membrane antibodyinduced crescentic nephritis in the rabbit A cellular source for interstitial collagen synthesis in inflammatory renal disease
    • Wiggins R, Goyal M, Merritt S, Killen PD: Vascular adventitial cell expression of collagen I messenger ribonucleic acid in anti- glomerular basement membrane antibodyinduced crescentic nephritis in the rabbit. A cellular source for interstitial collagen synthesis in inflammatory renal disease. Lab Invest 1993;68:557-565.
    • (1993) Lab Invest. , vol.68 , pp. 557-565
    • Wiggins, R.1    Goyal, M.2    Merritt, S.3    Killen, P.D.4
  • 148
    • 0030702125 scopus 로고    scopus 로고
    • Role of MCP-1 and RANTES in inflammation and progression to fibrosis during murine crescentic nephritis
    • Lloyd CM, Dorf ME, Proudfoot A, Salant DJ, Gutierrez- Ramos JC: Role of MCP- 1 and RANTES in inflammation and progression to fibrosis during murine crescentic nephritis. J Leukocyte Biol 1997;62:676-680.
    • (1997) J. Leukocyte. Biol. , vol.62 , pp. 676-680
    • Lloyd, C.M.1    Dorf, M.E.2    Proudfoot, A.3    Salant, D.J.4    Gutierrez-Ramos, J.C.5
  • 149
    • 0030903307 scopus 로고    scopus 로고
    • RANTES and monocyte chemoattractant protein-1 MCP- 1 play an important role in the inflammatory phase of crescentic nephritis but only MCP-1 is involved in crescent formation and interstitial fibrosis
    • Lloyd CM, Minto AW, Dorf ME, Proudfoot A, Wells TN, Salant DJ, Gutierrez- Ramos JC: RANTES and monocyte chemoattractant protein- 1 (MCP- 1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP- 1 is involved in crescent formation and interstitial fibrosis. J Exp Med 1997;185:1371-1380.
    • (1997) J. Exp. Med. , vol.185 , pp. 1371-1380
    • Lloyd, C.M.1    Minto, A.W.2    Dorf, M.E.3    Proudfoot, A.4    Wells, T.N.5    Salant, D.J.6    Gutierrez-Ramos, J.C.7
  • 150
    • 0031884815 scopus 로고    scopus 로고
    • Colocalization of collagen overexpression and inflammatory cell infiltration in the two-kidney oneclip rat model from the early days of hypertension onward
    • Xu Y, Appay MD, Heudes D, Lemoine R, Hinglais N, Michel JB, Bariety J: Colocalization of collagen overexpression and inflammatory cell infiltration in the two- kidney oneclip rat model from the early days of hypertension onward. Virchows Arch 1998;432:267-277.
    • (1998) Virchows. Arch. , vol.432 , pp. 267-277
    • Xu, Y.1    Appay, M.D.2    Heudes, D.3    Lemoine, R.4    Hinglais, N.5    Michel, J.B.6    Bariety, J.7
  • 151
    • 0031011375 scopus 로고    scopus 로고
    • Myofibroblast phenotypes expression in experimental renal scarring
    • Muchaneta- Kubara EC and el Nahas AM: Myofibroblast phenotypes expression in experimental renal scarring. Nephrol Dial Transplant 1997;12:904-915.
    • (1997) Nephrol. Dial. Transplant , vol.12 , pp. 904-915
    • Muchaneta-Kubara, E.C.1    El Nahas, A.M.2
  • 153
    • 34547419062 scopus 로고    scopus 로고
    • Fibrocytes: A new insight into kidney fibrosis
    • Wada T, Sakai N, Matsushima K, Kaneko S: Fibrocytes: a new insight into kidney fibrosis. Kidney Int 2007;72:269-273.
    • (2007) Kidney Int , vol.72 , pp. 269-273
    • Wada, T.1    Sakai, N.2    Matsushima, K.3    Kaneko, S.4
  • 154
    • 33749024991 scopus 로고    scopus 로고
    • Secondary lymphoid tissue chemokine SLC/CCL21/CCR7 signaling regulates fibrocytes in renal fibrosis
    • USA
    • Sakai N, Wada T, Yokoyama H, Lipp M, Ueha S, Matsushima K, Kaneko S: Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis. Proc Natl Acad Sci USA 2006;103:14098-14103.
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , pp. 14098-14103
    • Sakai, N.1    Wada, T.2    Yokoyama, H.3    Lipp, M.4    Ueha, S.5    Matsushima, K.6    Kaneko, S.7
  • 158
    • 33847655732 scopus 로고    scopus 로고
    • The contribution of bone marrow-derived cells to the development of renal interstitial fibrosis
    • Li J, Deane JA, Campanale NV, Bertram JF, Ricardo SD: The contribution of bone marrow- derived cells to the development of renal interstitial fibrosis. Stem Cells 2007;25:697-706.
    • (2007) Stem. Cells , vol.25 , pp. 697-706
    • Li, J.1    Deane, J.A.2    Campanale, N.V.3    Bertram, J.F.4    Ricardo, S.D.5
  • 159
    • 0344826546 scopus 로고    scopus 로고
    • Are CD34+ cells found in renal interstitial fibrosis
    • Okon K, Szumera A, Kuzniewski M: Are CD34+ cells found in renal interstitial fibrosis? Am J Nephrol 2003;23:409-414.
    • (2003) Am. J. Nephrol. , vol.23 , pp. 409-414
    • Okon, K.1    Szumera, A.2    Kuzniewski, M.3
  • 162
    • 0029157019 scopus 로고
    • Transformations between epithelium and mesenchyme: Normal pathological and experimentally induced
    • Hay ED and Zuk A: Transformations between epithelium and mesenchyme: normal, pathological, and experimentally induced. Am J Kidney Dis 1995;26:678-690.
    • (1995) Am. J. Kidney Dis. , vol.26 , pp. 678-690
    • Hay, E.D.1    Zuk, A.2
  • 163
    • 0038349941 scopus 로고    scopus 로고
    • New insights into mechanisms of fibrosis in immune renal injury
    • Springer
    • Strutz F, Neilson EG: New insights into mechanisms of fibrosis in immune renal injury. Springer Semin Immunopathol 2003;24:459-476.
    • (2003) Semin. Immunopathol. , vol.24 , pp. 459-476
    • Strutz, F.1    Neilson, E.G.2
  • 165
    • 0346724511 scopus 로고    scopus 로고
    • Epithelialmesenchymal transition and its implications for fibrosis
    • Kalluri R, Neilson EG: Epithelialmesenchymal transition and its implications for fibrosis. J Clin Invest 2003;112:1776-1784.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 166
    • 0347993932 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in renal fibrogenesis: Pathologic significance molecular mechanism and therapeutic intervention
    • Liu Y: Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol 2004;15:1-12.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1-12
    • Liu, Y.1
  • 167
    • 33644638349 scopus 로고    scopus 로고
    • Renal fibrosis: New insights into the pathogenesis and therapeutics
    • Liu Y: Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int 2006;69:213-217.
    • (2006) Kidney Int , vol.69 , pp. 213-217
    • Liu, Y.1
  • 170
    • 0036854980 scopus 로고    scopus 로고
    • Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy
    • Yang J, Shultz RW, Mars WM, WegnerRE, Li Y, Dai C, Nejak K, Liu Y: Disruption of tissue- type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy. J Clin Invest 2002; 110:1525-1538.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1525-1538
    • Yang, J.1    Shultz, R.W.2    Mars, W.M.3    Wegner, R.E.4    Li, Y.5    Dai, C.6    Nejak, K.7    Liu, Y.8
  • 171
    • 33947233187 scopus 로고    scopus 로고
    • Plasmin ogen promotes renal interstitial fibrosis by promoting epithelial-to mesenchymal transition: Role of plasmin-activated signals
    • Zhang G, Kernan KA, Collins SJ, Cai X, Lopez- Guisa JM, Degen JL, Shvil Y, Eddy AA: Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial- to mesenchymal transition: role of plasmin- activated signals. J Am Soc Nephrol 2007;18:846-859.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 846-859
    • Zhang, G.1    Kernan, K.A.2    Collins, S.J.3    Cai, X.4    Lopez-Guisa, J.M.5    Degen, J.L.6    Shvil, Y.7    Eddy, A.A.8
  • 172
    • 32644477571 scopus 로고    scopus 로고
    • Obstructive nephropathy: Insights from genetically engineered animals
    • Bascands JL, Schanstra JP: Obstructive nephropathy: insights from genetically engineered animals. Kidney Int 2005;68:925-937.
    • (2005) Kidney Int , vol.68 , pp. 925-937
    • Bascands, J.L.1    Schanstra, J.P.2
  • 173
    • 34250856260 scopus 로고    scopus 로고
    • Twist relates to tubular epithelial-mesenchymal transition and interstitial fibrogenesis in the obstructed kidney
    • Kida Y, Asahina K, Teraoka H, Gitelman I, Sato T: Twist relates to tubular epithelial- mesenchymal transition and interstitial fibrogenesis in the obstructed kidney. J Histochem Cytochem 2007;55:661-673.
    • (2007) J. Histochem. Cytochem. , vol.55 , pp. 661-673
    • Kida, Y.1    Asahina, K.2    Teraoka, H.3    Gitelman, I.4    Sato, T.5
  • 174
    • 0036138824 scopus 로고    scopus 로고
    • Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis
    • Yang J, Liu Y: Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis. J Am Soc Nephrol 2002;13:96-107.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 96-107
    • Yang, J.1    Liu, Y.2
  • 175
    • 34548506249 scopus 로고    scopus 로고
    • PINCH-1 promotes tubular epithelial-tomesenchymal transition by interacting with integrin-linked kinase
    • Li Y, Dai C, Wu C, Liu Y: PINCH- 1 promotes tubular epithelial- tomesenchymal transition by interacting with integrin- linked kinase. J Am Soc Nephrol 2007;18:2534-2543.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2534-2543
    • Li, Y.1    Dai, C.2    Wu, C.3    Liu, Y.4
  • 179
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A: Targeted disruption of TGF- beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 2003; 112:1486-1494.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 180
    • 33845242306 scopus 로고    scopus 로고
    • Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy
    • Tan X, Li Y, Liu Y: Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy. J Am Soc Nephrol 2006;17:3382-3393.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3382-3393
    • Tan, X.1    Li, Y.2    Liu, Y.3
  • 181
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J, Liu Y: Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 2001;159:1465-1475.
    • (2001) Am. J. Pathol. , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 184
    • 0038582623 scopus 로고    scopus 로고
    • Gelatinase A MMP-2 is necessary and sufficient for renal tubular cell epithelialmesenchymal transformation
    • Cheng S, Lovett DH: Gelatinase A (MMP- 2) is necessary and sufficient for renal tubular cell epithelialmesenchymal transformation. Am J Pathol 2003;162:1937-1949.
    • (2003) Am. J. Pathol. , vol.162 , pp. 1937-1949
    • Cheng, S.1    Lovett, D.H.2
  • 186
    • 0141720342 scopus 로고    scopus 로고
    • Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis
    • Li Y, Yang J, Dai C, Wu C, Liu Y: Role for integrin- linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. J Clin Invest 2003;112:503-516.
    • (2003) J. Clin. Invest. , vol.112 , pp. 503-516
    • Li, Y.1    Yang, J.2    Dai, C.3    Wu, C.4    Liu, Y.5
  • 187
    • 33748031093 scopus 로고    scopus 로고
    • Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease
    • Burns WC, Twigg SM, Forbes JM, Pete J, Tikellis C, Thallas- Bonke V, Thomas MC, Cooper ME, Kantharidis P: Connective tissue growth factor plays an important role in advanced glycation end product- induced tubular epithelial- to- mesenchymal transition: implications for diabetic renal disease. J Am Soc Nephrol 2006;17:2484-2494.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2484-2494
    • Burns, W.C.1    Twigg, S.M.2    Forbes, J.M.3    Pete, J.4    Tikellis, C.5    Thallas-Bonke, V.6    Thomas, M.C.7    Cooper, M.E.8    Kantharidis, P.9
  • 188
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-tomesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R: BMP- 7 counteracts TGF- beta1- induced epithelial- tomesenchymal transition and reverses chronic renal injury. Nat Med 2003;9:964-968.
    • (2003) Nat. Med. , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 189
    • 0033865917 scopus 로고    scopus 로고
    • Progressive renal fibrosis in routine polycystic kidney disease: An immunohistochemical observation
    • DOI 10.1046/j.1523-1755.2000.00205.x
    • Okada H, Ban S, Nagao S, Takahashi H, Suzuki H, Neilson EG: Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation. Kidney Int 2000;58:587-597. (Pubitemid 30620008)
    • (2000) Kidney International , vol.58 , Issue.2 , pp. 587-597
    • Okada, H.1    Ban, S.2    Nagao, S.3    Takahashi, H.4    Suzuki, H.5    Neilson, E.G.6
  • 191
    • 73549092294 scopus 로고    scopus 로고
    • Endothelialmyofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice
    • Li J, Qu X, Bertram JF: Endothelialmyofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin- induced diabetic mice. Am J Pathol 2009;175:1380-1388.
    • (2009) Am. J. Pathol. , vol.175 , pp. 1380-1388
    • Li, J.1    Qu, X.2    Bertram, J.F.3
  • 192
    • 73949148649 scopus 로고    scopus 로고
    • The origin of renal fibroblasts and progression of kidney disease
    • Cook HT: The origin of renal fibroblasts and progression of kidney disease. Am J Pathol 2010;176: 22-24.
    • (2010) Am. J. Pathol. , vol.176 , pp. 22-24
    • Cook, H.T.1
  • 193
    • 22244473343 scopus 로고    scopus 로고
    • The fallacy of epithelial mesenchymal transition in neoplasia
    • Tarin D: The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res 2005;65: 5996-6001.
    • (2005) Cancer Res. , vol.65 , pp. 5996-6001
    • Tarin, D.1
  • 194
    • 39649102143 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is important to metastasis but questions remain
    • Garber K: Epithelial- to- mesenchymal transition is important to metastasis, but questions remain. J Natl Cancer Inst 2008;100:232-239.
    • (2008) J. Natl. Cancer Inst. , vol.100 , pp. 232-239
    • Garber, K.1
  • 195
    • 45849091082 scopus 로고    scopus 로고
    • Kidney injury molecule-1 KIM-1: A specific and sensitive biomarker of kidney injury
    • Bonventre JV: Kidney injury molecule- 1 (KIM- 1): a specific and sensitive biomarker of kidney injury. Scand J Clin Lab Invest Suppl 2008;241:78-83.
    • (2008) Scand. J. Clin. Lab Invest. Suppl. , vol.241 , pp. 78-83
    • Bonventre, J.V.1
  • 199
    • 33645086673 scopus 로고    scopus 로고
    • Inhibition of the renin angiotensin system decreases fibrogenic cytokine expression in tacrolimus nephrotoxicity in rats
    • Deniz H, Ogutmen B, Cakalagaoglu F, Tuglular S, Ozener C, Akoglu E: Inhibition of the renin angiotensin system decreases fibrogenic cytokine expression in tacrolimus nephrotoxicity in rats. Transplant Proc 2006;38:483-486.
    • (2006) Transplant Proc. , vol.38 , pp. 483-486
    • Deniz, H.1    Ogutmen, B.2    Cakalagaoglu, F.3    Tuglular, S.4    Ozener, C.5    Akoglu, E.6
  • 200
    • 39349098768 scopus 로고    scopus 로고
    • Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury
    • Zhang PL, Rothblum LI, Han WK, Blasick TM, Potdar S, Bonventre JV: Kidney injury molecule- 1 expression in transplant biopsies is a sensitive measure of cell injury. Kidney Int 2008;73:608-614.
    • (2008) Kidney Int , vol.73 , pp. 608-614
    • Zhang, P.L.1    Rothblum, L.I.2    Han, W.K.3    Blasick, T.M.4    Potdar, S.5    Bonventre, J.V.6
  • 201
    • 52649111586 scopus 로고    scopus 로고
    • Spectrum of renal involvement in paroxysmal nocturnal hemoglobinuria: Report of three cases and a brief review of the literature
    • Nair RK, Khaira A, Sharma A, Mahajan S, Dinda AK: Spectrum of renal involvement in paroxysmal nocturnal hemoglobinuria: report of three cases and a brief review of the literature. Intl Urol Nephrol 2008;40:471-475.
    • (2008) Intl Urol Nephrol , vol.40 , pp. 471-475
    • Nair, R.K.1    Khaira, A.2    Sharma, A.3    Mahajan, S.4    Dinda, A.K.5
  • 203
    • 1842359814 scopus 로고
    • Renal hemosiderosis in the hemolytic anemias: Diagnosis by means of needle biopsy
    • Leonardi P, Ruol A: Renal hemosiderosis in the hemolytic anemias: diagnosis by means of needle biopsy. Blood 1960;16:1029-1038.
    • (1960) Blood , vol.16 , pp. 1029-1038
    • Leonardi, P.1    Ruol, A.2
  • 204
    • 30944440976 scopus 로고    scopus 로고
    • Antibodies against macrophages that overlap in specificity with fibroblasts
    • Le Hir M, Kaissling B: Antibodies against macrophages that overlap in specificity with fibroblasts. Kidney Int 2005;68:2400-2001.
    • (2005) Kidney Int , vol.68 , pp. 2400-2001
    • Le Hir, M.1    Kaissling, B.2
  • 205
    • 12344256754 scopus 로고    scopus 로고
    • Pathways to nephron loss starting from glomerular diseases-insights from animal models
    • Kriz W, Le Hir M: Pathways to nephron loss starting from glomerular diseases- insights from animal models. Kidney Int 2005;67:404-419.
    • (2005) Kidney Int , vol.67 , pp. 404-419
    • Kriz, W.1    Le Hir, M.2
  • 206
    • 33745825957 scopus 로고    scopus 로고
    • Why kidneys fail: Report from an American society of nephrology advances in research con ference
    • Schnaper HW, Kopp JB: Why kidneys fail: report from an American Society of Nephrology Advances in Research Con ference. J Am Soc Nephrol 2006;17:1777-1781.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1777-1781
    • Schnaper, H.W.1    Kopp, J.B.2
  • 207
    • 79551496575 scopus 로고    scopus 로고
    • Histopathological analysis of interstitial fibrosis epithelial mesenchymal transition in fibrosis: Whither the controversy
    • Morrissey JJ, Liu Y, Lovett DH, Barnes JL, Kriz W American Society of Nephrology Renal Week San Diego
    • Kriz W: Histopathological analysis of interstitial fibrosis. Epithelial mesenchymal transition in fibrosis: whither the controversy? Symposium Panel: Morrissey JJ, Liu Y, Lovett DH, Barnes JL, Kriz W. American Society of Nephrology Renal Week San Diego, 2006.
    • (2006) Symposium Panel
    • Kriz, W.1
  • 210
    • 44349140101 scopus 로고    scopus 로고
    • Hypoxia-inducible factor signaling in the development of tissue fibrosis
    • Higgins DF, Kimura K, Iwano M, Haase VH: Hypoxia- inducible factor signaling in the development of tissue fibrosis. Cell Cycle 2008;7:1128-1132.
    • (2008) Cell Cycle. , vol.7 , pp. 1128-1132
    • Higgins, D.F.1    Kimura, K.2    Iwano, M.3    Haase, V.H.4
  • 211
    • 49849099578 scopus 로고    scopus 로고
    • Macrophage phenotype and renal fibrosis in obstructive nephropathy
    • Nishida M, Hamaoka K: Macrophage phenotype and renal fibrosis in obstructive nephropathy. Nephron Exp Nephrol 2008;110:e31-e36.
    • (2008) Nephron. Exp. Nephrol. , vol.110
    • Nishida, M.1    Hamaoka, K.2
  • 213
    • 0036144144 scopus 로고    scopus 로고
    • Protein S100A4: Too long overlooked by pathologists
    • Mazzucchelli L: Protein S100A4: too long overlooked y pathologists? Am J Pathol 2002;160:7-13.
    • (2002) Am. J. Pathol. , vol.160 , pp. 7-13
    • Mazzucchelli, L.1
  • 216
    • 0028931948 scopus 로고
    • Immunocytochemical distribution of the calcium-binding protein p9Ka in normal rat tissues: Variation in the cellular location in different tissues
    • Gibbs FE, Barraclough R, Platt- Higgins A, Rudland PS, Wilkinson MC, Parry EW: Immunocytochemical distribution of the calcium- binding protein p9Ka in normal rat tissues: variation in the cellular location in different tissues. J Histochem Cytochem1995;43:169-180.
    • (1995) J. Histochem. Cytochem. , vol.43 , pp. 169-180
    • Gibbs, F.E.1    Barraclough, R.2    Platt-Higgins, A.3    Rudland, P.S.4    Wilkinson, M.C.5    Parry, E.W.6
  • 220
    • 33745819270 scopus 로고    scopus 로고
    • Chronic allograft nephropathy: Intraepithelial signals generated by transforming growth factor- beta and bone morphogenetic protein-7
    • Tyler JR, Robertson H, Booth TA, Burt AD, Kirby JA: Chronic allograft nephropathy: intraepithelial signals generated by transforming growth factor- beta and bone morphogenetic protein- 7. Am J Transplant 2006; 6:1367-1376.
    • (2006) Am. J. Transplant , vol.6 , pp. 1367-1376
    • Tyler, J.R.1    Robertson, H.2    Booth, T.A.3    Burt, A.D.4    Kirby, J.A.5
  • 222
    • 20544462075 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition during late deterioration of human kidney transplants: The role of tubular cells in fibrogenesis
    • Vongwiwatana A, Tasanarong A, Rayner DC, Melk A, Halloran PF: Epithelial to mesenchymal transition during late deterioration of human kidney transplants: the role of tubular cells in fibrogenesis. Am J Transplant 2005;5:1367-1374.
    • (2005) Am. J. Transplant , vol.5 , pp. 1367-1374
    • Vongwiwatana, A.1    Tasanarong, A.2    Rayner, D.C.3    Melk, A.4    Halloran, P.F.5
  • 224
    • 68749088353 scopus 로고    scopus 로고
    • A case report suggesting the occurrence of epithelial-mesenchymal transition in obstructive nephropathy
    • Inoue T, Okada H, Takenaka T, Watanabe Y, Suzuki H: A case report suggesting the occurrence of epithelial- mesenchymal transition in obstructive nephropathy. Clin Exp Nephrol 2009;13:385-388.
    • (2009) Clin. Exp. Nephrol. , vol.13 , pp. 385-388
    • Inoue, T.1    Okada, H.2    Takenaka, T.3    Watanabe, Y.4    Suzuki, H.5
  • 225
    • 0036088906 scopus 로고    scopus 로고
    • Renal fibrosis extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells
    • Zeisberg M, Maeshima Y, Mosterman B, Kalluri R: Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. Am J Pathol 2002;160:2001-2008.
    • (2002) Am. J. Pathol. , vol.160 , pp. 2001-2008
    • Zeisberg, M.1    Maeshima, Y.2    Mosterman, B.3    Kalluri, R.4
  • 227
    • 24944554995 scopus 로고    scopus 로고
    • Kidneys with heavy proteinuria show fibrosis inflammation and oxidative stress but no tubular phenotypic change
    • Kuusniemi AM, Lapatto R, Holmberg C, Karikoski R, Rapola J, Jalanko H: Kidneys with heavy proteinuria show fibrosis, inflammation, and oxidative stress, but no tubular phenotypic change. Kidney Int 2005;68:121-132.
    • (2005) Kidney Int , vol.68 , pp. 121-132
    • Kuusniemi, A.M.1    Lapatto, R.2    Holmberg, C.3    Karikoski, R.4    Rapola, J.5    Jalanko, H.6
  • 228
    • 77955602944 scopus 로고    scopus 로고
    • Resolved: EMT produces fibroblasts in the kidney debate
    • Zeisberg M, Duffield JS: Resolved: EMT produces fibroblasts in the kidney. Debate. J Am Soc Nephrol 2010;21:1247-1253.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1247-1253
    • Zeisberg, M.1    Duffield, J.S.2
  • 229
    • 77950565076 scopus 로고    scopus 로고
    • Autophagy is a component of epithelial cell fate in obstructive uropathy
    • Li L, Zepeda-Orozoco D, Black R, Lin F: Autophagy is a component of epithelial cell fate in obstructive uropathy. Am J Pathol 2010;176:1767-1778.
    • (2010) Am. J. Pathol. , vol.176 , pp. 1767-1778
    • Li, L.1    Zepeda-Orozoco, D.2    Black, R.3    Lin, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.