Chronic aristolochic acid toxicity in rabbits: A model of Chinese herbs nephropathy?

Kidney International

Volumn 59, Issue 6, 2001, Pages 2164-2173

  Cosyns, Jean Pierre ^a   Dehoux, Jean Paul ^a   Guiot, Yves ^a   Goebbels, Rose Marie ^a   Robert, Annie ^a   Bernard, Alfred M ^a   Van Ypersele De Strihou, Charles ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Cancer; Fibrosis; Slimming pills; Toxic interstitial nephritis; Urothelial atypia

Indexed keywords

ARISTOLOCHIC ACID; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; INTERSTITIAL NEPHRITIS; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY PROXIMAL TUBULE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RABBIT; URINARY TRACT TUMOR;

EID: 0035024391     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.0590062164.x     Document Type: Article

References (35)

1. Vanherweghem JL, Depierreux M, Tielemans C, et al: Rapidly progressive interstitial renal fibrosis in young women: Association with slimming regimen including Chinese herbs. Lancet 341:387-391, 1993
2. Cosyns JP, Jadoul M. Squifflet JP, et al: Urothelial lesions in Chinese-herb nephropathy. Am J Kidney Dis 33:1011-1017, 1999
3. Nortier JL, Muniz Martinez Mc, Schmeiser HH, et al; Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). N Engl J Med 342:1686-1692, 2000
4. Vanhaelen M, Vanhaelen-Fastre R, But P, Vanherweghem JL: Identification of aristolochic acid in Chinese herbs. (letter) Lancet 343:174, 1994
5. Schmeiser HH, Bieler CA, Wiessler M. et al: Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy. Cancer Res 56:2025-2028, 1996
6. 32P-post-labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy. Carcinogenesis 18:1063-1067, 1997
7. Méhes J, Decsi L. Varga F, Kovács S: Selektive chemische Ausschaltung der Harnkanälchen I, Ordnung bei Kaninchen. Naunyn Schmiedebergs Arch Exp Path U Pharmak 234:S548-S565, 1958
8. Jackson L, Kofman S, Weiss A, Brodovsky H: Aristolochic acid (NSC-50413): Phase I clinical study. Cancer Chemother Rep 42:35-37, 1964
9. Mengs U: Acute toxicity of aristolochic acid in rodents. Arch Toxicol 59:328-331, 1987
10. Mengs U, Stotzem CD: Renal toxicity of aristolochic acid in rats as an example of nephrotoxicity testing in routine toxicology. Arch Toxicol 67:307-311, 1993
11. Cosyns JP, Goebbels RM, Liberton V, et al: Chinese herbs nephropathy-associated slimming regimen induces tumours in the forestomach but no interstitial nephropathy in rats. Arch Toxicol 72:738-743, 1998
12. Kessler DA: Cancer and herbs. N Engl J Med 342:1742-1743, 2000
13. Bartels H, Bohmer M, Heierli C: Serum creatinine determination without protein precipitation. Clin Chim Acta 37:193-197, 1972
14. Schmidt FH: Die enzymatische Bestimmung von Glucose und Fructose nebeneinander. Klin Wochenschr 39:1244-1247, 1961
15. Weichselbaum TE: An accurate and rapid method for the determination of proteins in small amounts of blood serum and plasma. Am J Clin Pathol 16:40-49, 1946
16. Banauch D, Brummer W, Ebeling W, et al: A glucose deshydrogenase for the determination of glucose concentrations in body fluids. Z Klin Chem Klin Biochem 13:101-107, 1975
17. Watanabe N, Kamei S, Ohkubo A, et al: Urinary protein as measured with a pyrogallol red-molybdate complex manually and in a Hitachi 726 automated analyzer. Clin Chem 32:1551-1554, 1986
18. Matsubara T, Okuzono H, Tamagawa S: Proposal for an improved reagent in the hemiglobincyanide method, in Modern Concepts in Haematology, edited by Izak G, Lewis SM, New York, London, Academic Press, 1972, p 29-43
19. Joekes AM, Heptinstall RH, Porter KA: The nephrotic syndrome: A study of renal biopsies in 20 adult patients. Q J Med 27:495-516, 1958
20. Bankir L, De Rouffignac C: Urinary concentrating ability: Insights from comparative anatomy. Am J Physiol 249:R643-R666, 1985
21. Venkatachalam MA, Kriz W: Anatomy, in Heptinstall's Pathology of the Kidney (vol 1), edited by Jennette JC, Olson JL, Schwartz MM, Silva FG, Philadelphia, Lippincott-Raven Publishers. 1998, p 3-66
22. Kashgarian M: Acute tubular necrosis and ischemic renal injury, in Heptinstall's Pathology of the Kidney (vol 2), edited by Jennette JC, Olson JL, Schwartz MM, Silva FG, Philadelphia. Lippincott-Raven Publishers, 1998, p 863-889
23. Cosyns JP, Jadoul M, Squifflet JP, et al: Chinese herbs nephropathy: A clue to Balkan endemic nephropathy? Kidney Int 45:1680-1688, 1994
24. Depierreux M, Van Damme B, Vanden Houte K, Vanherweghem JL: Pathologic aspects of a newly described nephropathy related to the prolonged use of Chinese herbs. Am J Kidney Dis 24:172-180, 1994
25. Reginster F, Jadoul M. Van Ypersele De Strihou C: Chinese herbs nephropathy presentation, natural history and fate after transplantation. Nephrol Dial Transplant 12:81-86, 1997
26. Kabanda A. Jadoul M, Lauwerys R, et al: Low molecular weight proteinuria in Chinese herbs nephropathy. Kidney Int 48:1571-1576, 1995
27. Pena JM, Borrás M, Ramos J, Montoliu J: Rapidly progressive interstitial renal fibrosis due to a chronic intake of a herb (Aristolochia pistolochia) infusion. Nephrol Dial Transplant 11:1359-1360, 1996
28. Tanaka A, Nishida R, Sawai K, et al: Traditional remedy-induced Chinese herbs nephropathy showing rapid deterioration of renal function. Nippon Jinzo Gakkai Shi 39:794-797, 1997
29. Vanherweghem JL, Cuykens JJ, Vandenbergh P, et al: Valvular heart disease and Chinese-herb nephropathy. Lancet 351:991, 1998
30. Lord GM, Tagore R, Cook T, et al: Nephropathy caused by Chinese herbs in the UK. Lancet 354:481-482, 1999
31. Schmeiser HH, Schoepe KB, Wiessler M: DNA adduct formation of aristolochic acid I and II in vitro and in vivo. Carcinogenesis 9:297-303, 1988
32. Krumbiegel G, Hallensleben J, Mennicke WH, et al: Studies on the metabolism of aristolochic acids I and II. Xenobiotica 17:981-991, 1987
33. Mengs U, Lang W, Poch JA: The carcinogenic action of aristolochic acid in rats. Arch Toxicol 51:107-119, 1982
34. Mengs U: Tumour induction in mice following exposure to aristolochic acid. Arch Toxicol 61:504-505, 1988
35. Solez K, Axelsen RA, Benediktsson H, et al: International standardization of criteria for the histologic diagnosis of renal allograft rejection: The Banff working classification of kidney transplant pathology. Kidney Int 44:411-422, 1993