메뉴 건너뛰기




Volumn 6, Issue 6, 2006, Pages 1367-1376

Chronic allograft nephropathy: Intraepithelial signals generated by transforming growth factor-β and bone morphogenetic protein-7

Author keywords

Bone morphogenic protein 7; Chronic allograft nephropathy; Epithelial to mesenchymal transition; Renal tubular epithelial cell; Transforming growth factor

Indexed keywords

CALVASCULIN; OSTEOGENIC PROTEIN 1; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 33745819270     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01339.x     Document Type: Article
Times cited : (38)

References (36)
  • 1
    • 0036775985 scopus 로고    scopus 로고
    • Late deterioration of organ transplants: A problem in injury and homeostasis
    • Gourishankar S, Halloran PF. Late deterioration of organ transplants: A problem in injury and homeostasis. Curr Opin Immunol 2002; 14: 576-583.
    • (2002) Curr Opin Immunol , vol.14 , pp. 576-583
    • Gourishankar, S.1    Halloran, P.F.2
  • 3
    • 20544462075 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition during late deterioration of human kidney transplants: The role of tubular cells in fibrogenesis
    • Vongwiwatana A, Tasanarong A, Rayner DC, Melk A, Halloran PF. Epithelial to mesenchymal transition during late deterioration of human kidney transplants: The role of tubular cells in fibrogenesis. Am J Transplant 2005; 5: 1367-1374.
    • (2005) Am J Transplant , vol.5 , pp. 1367-1374
    • Vongwiwatana, A.1    Tasanarong, A.2    Rayner, D.C.3    Melk, A.4    Halloran, P.F.5
  • 4
    • 0942276287 scopus 로고    scopus 로고
    • Chronic renal allograft dysfunction: The role of T cell-mediated tubular epithelial to mesenchymal cell transition
    • Robertson H, Ali S, McDonnell BJ, Burt AD, Kirby JA. Chronic renal allograft dysfunction: The role of T cell-mediated tubular epithelial to mesenchymal cell transition. J Am Soc Nephrol 2004; 15: 390-397.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 390-397
    • Robertson, H.1    Ali, S.2    McDonnell, B.J.3    Burt, A.D.4    Kirby, J.A.5
  • 5
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112: 1776-1784.
    • (2003) J Clin Invest , vol.112 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 6
    • 0032827029 scopus 로고    scopus 로고
    • Embryonic renal epithelia: Induction, nephrogenesis, and cell differentiation
    • Horster MF, Braun GS, Huber SM. Embryonic renal epithelia: Induction, nephrogenesis, and cell differentiation. Physiol Rev 1999; 79: 1157-1191.
    • (1999) Physiol Rev , vol.79 , pp. 1157-1191
    • Horster, M.F.1    Braun, G.S.2    Huber, S.M.3
  • 7
    • 0031055346 scopus 로고    scopus 로고
    • Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos
    • Dudley AT, Robertson EJ. Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos. Dev Dyn 1997; 208: 349-362.
    • (1997) Dev Dyn , vol.208 , pp. 349-362
    • Dudley, A.T.1    Robertson, E.J.2
  • 9
    • 0036233040 scopus 로고    scopus 로고
    • Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
    • Strutz F, Zeisberg M, Ziyadeh FN et al. Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int 2002; 61: 1714-1728.
    • (2002) Kidney Int , vol.61 , pp. 1714-1728
    • Strutz, F.1    Zeisberg, M.2    Ziyadeh, F.N.3
  • 10
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGFβ1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H et al. BMP-7 counteracts TGFβ1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 2003; 9: 964-968.
    • (2003) Nat Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3
  • 11
    • 14844290237 scopus 로고    scopus 로고
    • Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney
    • Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J Biol Chem 2005; 280: 8094-8100.
    • (2005) J Biol Chem , vol.280 , pp. 8094-8100
    • Zeisberg, M.1    Shah, A.A.2    Kalluri, R.3
  • 12
    • 0036149123 scopus 로고    scopus 로고
    • BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells
    • Gould SE, Day M, Jones SS, Dorai H. BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells. Kidney Int 2002; 61: 51-60.
    • (2002) Kidney Int , vol.61 , pp. 51-60
    • Gould, S.E.1    Day, M.2    Jones, S.S.3    Dorai, H.4
  • 13
    • 21344443319 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in development and homeostasis of kidney
    • Simic P, Vukicevic S. Bone morphogenetic proteins in development and homeostasis of kidney. Cytokine Growth Factor Rev 2005; 16: 299-308.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 299-308
    • Simic, P.1    Vukicevic, S.2
  • 14
    • 0034758712 scopus 로고    scopus 로고
    • Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy
    • Wang SN, Lapage J, Hirschberg R. Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy. J Am Soc Nephrol 2001; 12: 2392-2399.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2392-2399
    • Wang, S.N.1    Lapage, J.2    Hirschberg, R.3
  • 15
    • 0032922119 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney
    • Simon M, Maresh JG, Harris SE et al. Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney. Am J Physiol 1999; 276: F382-F389.
    • (1999) Am J Physiol , vol.276
    • Simon, M.1    Maresh, J.G.2    Harris, S.E.3
  • 16
    • 0037468389 scopus 로고    scopus 로고
    • Tubulitis in renal allograft rejection: Role of TGFβ and IL-15 in development and maintenance of CD103+ intraepithelial T cells
    • Wong WK, Robertson H, Carroll HP, Ali S, Kirby JA. Tubulitis in renal allograft rejection: Role of TGFβ and IL-15 in development and maintenance of CD103+ intraepithelial T cells. Transplantation 2003; 75: 505-514.
    • (2003) Transplantation , vol.75 , pp. 505-514
    • Wong, W.K.1    Robertson, H.2    Carroll, H.P.3    Ali, S.4    Kirby, J.A.5
  • 17
    • 27144507950 scopus 로고    scopus 로고
    • Cyclosporine-A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells
    • McMorrow T, Gaffney MM, Slattery C, Campbell E, Ryan MP. Cyclosporine-A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells. Nephrol Dial Transplant 2005; 20: 2215-2225.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 2215-2225
    • McMorrow, T.1    Gaffney, M.M.2    Slattery, C.3    Campbell, E.4    Ryan, M.P.5
  • 18
    • 25144460253 scopus 로고    scopus 로고
    • Cyclosporine A-induced renal fibrosis - A role for epithelial-mesenchymal transition
    • Slattery C, Campbell E, McMorrow T, Ryan MP. Cyclosporine A-induced renal fibrosis - A role for epithelial-mesenchymal transition. Am J Pathol 2005; 167: 395-407.
    • (2005) Am J Pathol , vol.167 , pp. 395-407
    • Slattery, C.1    Campbell, E.2    McMorrow, T.3    Ryan, M.P.4
  • 19
    • 0034653688 scopus 로고    scopus 로고
    • TGFβ expression in renal transplant biopsies: A comparative study between cyclosporin-A and tacrolimus
    • Mohamed MA, Robertson H, Booth TA, Balupuri S, Kirby JA, Talbot D. TGFβ expression in renal transplant biopsies: A comparative study between cyclosporin-A and tacrolimus. Transplantation 2000; 69: 1002-1005.
    • (2000) Transplantation , vol.69 , pp. 1002-1005
    • Mohamed, M.A.1    Robertson, H.2    Booth, T.A.3    Balupuri, S.4    Kirby, J.A.5    Talbot, D.6
  • 20
    • 0036232706 scopus 로고    scopus 로고
    • T lymphocyte expression of thrombospondin-1 and adhesion to extracellular matrix components
    • Li SS, Ivanoff A, Bergstrom SE et al. T lymphocyte expression of thrombospondin-1 and adhesion to extracellular matrix components. Eur J Immunol 2002; 32: 1069-1079.
    • (2002) Eur J Immunol , vol.32 , pp. 1069-1079
    • Li, S.S.1    Ivanoff, A.2    Bergstrom, S.E.3
  • 21
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGFβ-Smad signalling
    • ten Dijke P, Hill CS. New insights into TGFβ-Smad signalling. Trends Biochem Sci 2004; 29: 265-273.
    • (2004) Trends Biochem Sci , vol.29 , pp. 265-273
    • Ten Dijke, P.1    Hill, C.S.2
  • 22
    • 0032475884 scopus 로고    scopus 로고
    • Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2
    • Macias-Silva M, Hoodless PA, Tang SJ, Buchwald M, Wrana JL. Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J Biol Chem 1998; 273: 25628-25636.
    • (1998) J Biol Chem , vol.273 , pp. 25628-25636
    • Macias-Silva, M.1    Hoodless, P.A.2    Tang, S.J.3    Buchwald, M.4    Wrana, J.L.5
  • 23
    • 2542441495 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 signals opposing transforming growth factor beta in mesangial cells
    • Wang S, Hirschberg R. Bone morphogenetic protein-7 signals opposing transforming growth factor beta in mesangial cells. J Biol Chem 2004; 279: 23200-23206.
    • (2004) J Biol Chem , vol.279 , pp. 23200-23206
    • Wang, S.1    Hirschberg, R.2
  • 24
    • 0346727324 scopus 로고    scopus 로고
    • Targeted disruption of TGFβ1/Smad3 signalling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
    • Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A. Targeted disruption of TGFβ1/Smad3 signalling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 2003; 112: 1486-1494.
    • (2003) J Clin Invest , vol.112 , pp. 1486-1494
    • Sato, M.1    Muragaki, Y.2    Saika, S.3    Roberts, A.B.4    Ooshima, A.5
  • 25
    • 0344845003 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and pathologies
    • Thiery JP. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 2003; 15: 740-746.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 740-746
    • Thiery, J.P.1
  • 26
    • 23044515502 scopus 로고    scopus 로고
    • The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix
    • Gregory KE, Ono RN, Charbonneau NL et al. The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix. J Biol Chem 2005; 280: 27970-27980.
    • (2005) J Biol Chem , vol.280 , pp. 27970-27980
    • Gregory, K.E.1    Ono, R.N.2    Charbonneau, N.L.3
  • 27
    • 0030789434 scopus 로고    scopus 로고
    • The interaction of the transforming growth factor-betas with heparin/heparan sulfate is isoform-specific
    • Lyon M, Rushton G, Gallagher JT. The interaction of the transforming growth factor-betas with heparin/heparan sulfate is isoform-specific. J Biol Chem 1997; 272: 18000-18006.
    • (1997) J Biol Chem , vol.272 , pp. 18000-18006
    • Lyon, M.1    Rushton, G.2    Gallagher, J.T.3
  • 28
    • 0042661060 scopus 로고    scopus 로고
    • Heparan sulfate is required for bone morphogenetic protein-7 signaling
    • Irie A, Habuchi H, Kimata K, Sanai Y. Heparan sulfate is required for bone morphogenetic protein-7 signaling. Biochem Biophys Res Comm 2003; 308: 858-865.
    • (2003) Biochem Biophys Res Comm , vol.308 , pp. 858-865
    • Irie, A.1    Habuchi, H.2    Kimata, K.3    Sanai, Y.4
  • 29
  • 30
    • 12144289926 scopus 로고    scopus 로고
    • Tubular chimerism occurs regularly in renal allografts and is not correlated to outcome
    • Mengel M, Jonigk D, Marwedel M et al. Tubular chimerism occurs regularly in renal allografts and is not correlated to outcome. J Am Soc Nephrol 2004; 15: 978-986.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 978-986
    • Mengel, M.1    Jonigk, D.2    Marwedel, M.3
  • 31
    • 0035651361 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function
    • Morrissey J, Hruska K, Quo G, Wang S, Chen Q, Klahr S. Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function. J Am Soc Nephrol 2002; 13 (Suppl 1): S14-S21.
    • (2002) J Am Soc Nephrol , vol.13 , Issue.1 SUPPL.
    • Morrissey, J.1    Hruska, K.2    Quo, G.3    Wang, S.4    Chen, Q.5    Klahr, S.6
  • 32
    • 0038756636 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: Mechanisms for epithelial mesenchymal transitions
    • Peinado H, Quintanilla M, Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: Mechanisms for epithelial mesenchymal transitions. J Biol Chem 2003; 278: 21113-21123.
    • (2003) J Biol Chem , vol.278 , pp. 21113-21123
    • Peinado, H.1    Quintanilla, M.2    Cano, A.3
  • 33
    • 21544440606 scopus 로고    scopus 로고
    • Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys
    • Le Hir M, Hegyi I, Cueni-Loffing D, Loffing J, Kaissling B. Characterization of renal interstitial fibroblast-specific protein 1/S100A4-positive cells in healthy and inflamed rodent kidneys. Histochem Cell Biol 2005; 123: 335-346.
    • (2005) Histochem Cell Biol , vol.123 , pp. 335-346
    • Le Hir, M.1    Hegyi, I.2    Cueni-Loffing, D.3    Loffing, J.4    Kaissling, B.5
  • 34
    • 0035956734 scopus 로고    scopus 로고
    • Tubulitis after renal transplantation: Demonstration of an association between CD103+T cells, TGFβ1 expression and rejection grade
    • Robertson H, Wong WK, Talbot D, Burt AD, Kirby JA. Tubulitis after renal transplantation: Demonstration of an association between CD103+T cells, TGFβ1 expression and rejection grade. Transplantation 2001; 71: 306-313.
    • (2001) Transplantation , vol.71 , pp. 306-313
    • Robertson, H.1    Wong, W.K.2    Talbot, D.3    Burt, A.D.4    Kirby, J.A.5
  • 35
    • 0033564093 scopus 로고    scopus 로고
    • Regulation of the epithelial cell-specific integrin, CD103, by human CD8(+) cytolytic T lymphocytes
    • Hadley GA, Rostapshova EA, Gomolka DM et al. Regulation of the epithelial cell-specific integrin, CD103, by human CD8(+) cytolytic T lymphocytes. Transplantation 1999; 67: 1418-1425.
    • (1999) Transplantation , vol.67 , pp. 1418-1425
    • Hadley, G.A.1    Rostapshova, E.A.2    Gomolka, D.M.3
  • 36
    • 4744356110 scopus 로고    scopus 로고
    • TGFβ induces Foxp3 + T-regulatory cells from CD4 + CD25-precursors
    • Fu S, Zhang N, Yopp AC et al. TGFβ induces Foxp3 + T-regulatory cells from CD4 + CD25-precursors. Am J Transplant 2004; 4: 1614-1627.
    • (2004) Am J Transplant , vol.4 , pp. 1614-1627
    • Fu, S.1    Zhang, N.2    Yopp, A.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.