메뉴 건너뛰기




Volumn 10, Issue 23, 1996, Pages 2981-2992

Collagen COL4A3 knockout: A mouse model for autosomal Alport syndrome

Author keywords

Alport syndrome; Basement membrane; mouse model

Indexed keywords

COLLAGEN TYPE 4; ENTACTIN; FIBRONECTIN; LAMININ; MEMBRANE PROTEIN; MESSENGER RNA; PROTEOHEPARAN SULFATE;

EID: 0029829425     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.23.2981     Document Type: Article
Times cited : (312)

References (62)
  • 2
    • 0002204298 scopus 로고
    • Alport syndrome
    • ed. R.W. Schrier and C.W. Gottschalk Little, Brown, Boston, MA
    • Atkin, C.L., M.C. Gregory, and W.A. Border. 1988. Alport syndrome. In Diseases of the kidney (ed. R.W. Schrier and C.W. Gottschalk), pp. 617-641. Little, Brown, Boston, MA.
    • (1988) Diseases of the Kidney , pp. 617-641
    • Atkin, C.L.1    Gregory, M.C.2    Border, W.A.3
  • 4
    • 0027255530 scopus 로고
    • Laminin, fibronectin, and goodpasture antigen detection in patients with alport's syndrome
    • Basta-Jovanovic, G., M. Savin, A.Z. fovanovic, R. Veljovic, and M. Sindjic. 1993. Laminin, fibronectin, and goodpasture antigen detection in patients with alport's syndrome. Renal Failure 15: 503-508.
    • (1993) Renal Failure , vol.15 , pp. 503-508
    • Basta-Jovanovic, G.1    Savin, M.2    Fovanovic, A.Z.3    Veljovic, R.4    Sindjic, M.5
  • 5
    • 0030272717 scopus 로고    scopus 로고
    • Expression of basement membrane type IV collagen chains during postnatal development in the murine cochlea
    • in press
    • Cosgrove, D., G. Samuelson, and J. Pinnt. 1996. Expression of basement membrane type IV collagen chains during postnatal development in the murine cochlea. Hearing Res. (in press).
    • (1996) Hearing Res.
    • Cosgrove, D.1    Samuelson, G.2    Pinnt, J.3
  • 6
    • 0027264683 scopus 로고
    • The glomerular distribution of laminin and fibronectin in glomerulonephritis
    • Davaris, P. 1993. The glomerular distribution of laminin and fibronectin in glomerulonephritis. Histol. Histopath. 8: 521-526.
    • (1993) Histol. Histopath. , vol.8 , pp. 521-526
    • Davaris, P.1
  • 7
    • 0028223630 scopus 로고
    • Identification of the Goodpasture antigen COL4A3 NC1, and four other NC1 domains of type IV collagen, by amino terminus sequence analysis of human glomerular basement membrane separated by two-dimentional electrophoresis
    • Derry, C.J., M. Pickering, C. Baker, and C.D. Pusey. 1994. Identification of the Goodpasture antigen COL4A3 NC1, and four other NC1 domains of type IV collagen, by amino terminus sequence analysis of human glomerular basement membrane separated by two-dimentional electrophoresis. Exp. Nephrol 2: 249-256.
    • (1994) Exp. Nephrol , vol.2 , pp. 249-256
    • Derry, C.J.1    Pickering, M.2    Baker, C.3    Pusey, C.D.4
  • 8
    • 0025204015 scopus 로고
    • Heterogeneous distribution of monomeric elements from the globular (NC1) domain of type IV collagen in renal basement membranes as revealed by high resolution quantitative immunohistochemistry
    • Desjardins, M., F. Gros, J. Weislander, M.-C. Gubler, and M. Bendayan. 1990. Heterogeneous distribution of monomeric elements from the globular (NC1) domain of type IV collagen in renal basement membranes as revealed by high resolution quantitative immunohistochemistry. Lab. Invest. 63: 637-646.
    • (1990) Lab. Invest. , vol.63 , pp. 637-646
    • Desjardins, M.1    Gros, F.2    Weislander, J.3    Gubler, M.-C.4    Bendayan, M.5
  • 10
    • 0028330824 scopus 로고
    • A monoclonal antibody marker for alport syndrome identified the alport antigen as the α5 chain of type IV collagen
    • Ding, J., C.E. Kashtan, W.W. Fan, M.M. Kleppel, M.J. Sun, R. Kalluri, E.G. Neilson, and A.F. Michael. 1994. A monoclonal antibody marker for alport syndrome identified the alport antigen as the α5 chain of type IV collagen. Kidney Int. 46: 1504-1506.
    • (1994) Kidney Int. , vol.46 , pp. 1504-1506
    • Ding, J.1    Kashtan, C.E.2    Fan, W.W.3    Kleppel, M.M.4    Sun, M.J.5    Kalluri, R.6    Neilson, E.G.7    Michael, A.F.8
  • 11
    • 0022355525 scopus 로고
    • Expression of nidogen and laminin in basement membranes during mouse embryogenesis and in teratocarcinoma cells
    • Dziadek, M. and R. Timpl. 1985. Expression of nidogen and laminin in basement membranes during mouse embryogenesis and in teratocarcinoma cells. Dev. Biol. 111: 372-382.
    • (1985) Dev. Biol. , vol.111 , pp. 372-382
    • Dziadek, M.1    Timpl, R.2
  • 12
    • 0025695293 scopus 로고
    • Immunohistochemical analysis of extracellular components in the glomerular sclerosis of patients with glomerulonephritis
    • Funabiki, K., S. Horikoshi, Y. Tomino, Y. Nagai, and H. Koide. 1990. Immunohistochemical analysis of extracellular components in the glomerular sclerosis of patients with glomerulonephritis. Clin. Nephrol. 34: 239-246.
    • (1990) Clin. Nephrol. , vol.34 , pp. 239-246
    • Funabiki, K.1    Horikoshi, S.2    Tomino, Y.3    Nagai, Y.4    Koide, H.5
  • 14
    • 0029616503 scopus 로고
    • Extracellular matrix and its receptors during development
    • Gullberg, D. and P. Eckblom. 1995 Extracellular matrix and its receptors during development. Int. I. Dev. Biol. 39: 845-854.
    • (1995) Int. I. Dev. Biol. , vol.39 , pp. 845-854
    • Gullberg, D.1    Eckblom, P.2
  • 16
    • 0024321189 scopus 로고
    • Distribution, ultrastructural localization, and ontogeny of the core protein of a heparan sulfate proteoglycan in human skin and other basement membranes
    • Horiguchi, Y., J.R. Couchman, V. Ljubimov, H. Yamasaki, and J.-D. Fine. 1989. Distribution, ultrastructural localization, and ontogeny of the core protein of a heparan sulfate proteoglycan in human skin and other basement membranes. J. Histochem. Cytochem. 37: 961-970.
    • (1989) J. Histochem. Cytochem. , vol.37 , pp. 961-970
    • Horiguchi, Y.1    Couchman, J.R.2    Ljubimov, V.3    Yamasaki, H.4    Fine, J.-D.5
  • 17
    • 0027494603 scopus 로고
    • Type IV collagen: Structure, gene organization, and role in human diseases
    • Hudson, B.G., S. Reeders, and K. Tryggvason. 1993. Type IV collagen: Structure, gene organization, and role in human diseases. J. Biol. Chem. 268: 26033-26036.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26033-26036
    • Hudson, B.G.1    Reeders, S.2    Tryggvason, K.3
  • 18
    • 0024535958 scopus 로고
    • A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction
    • Hunter, D.D., S. Vandana, J.P. Merlie, and J.R. Sanes. 1989. A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction. Nature 338: 229-234.
    • (1989) Nature , vol.338 , pp. 229-234
    • Hunter, D.D.1    Vandana, S.2    Merlie, J.P.3    Sanes, J.R.4
  • 19
    • 10544252729 scopus 로고
    • Hereditary nephritis (A1port's syndrome)
    • ed. E.H. Jenis and D.T. Lowenthal F.A. Davis Company, Philadelphia, PA
    • Jenis, E.H. and D.T. Lowenthal. 1977. Hereditary nephritis (A1port's syndrome). In Kidney biopsy interpretation (ed. E.H. Jenis and D.T. Lowenthal), pp. 125-136. F.A. Davis Company, Philadelphia, PA.
    • (1977) Kidney Biopsy Interpretation , pp. 125-136
    • Jenis, E.H.1    Lowenthal, D.T.2
  • 20
    • 0025930547 scopus 로고
    • Characterization of monoclonal antibodies to the globular domain of collagen IV
    • Johansson, C., R. Butkowski, and J. Wieslander. 1991. Characterization of monoclonal antibodies to the globular domain of collagen IV. Conn. Tissue Res. 25: 229-241.
    • (1991) Conn. Tissue Res. , vol.25 , pp. 229-241
    • Johansson, C.1    Butkowski, R.2    Wieslander, J.3
  • 21
    • 0019505159 scopus 로고
    • Cochlear abnormalities in Alport's syndrome
    • Johnsson, L.-G. and I.K. Arenberg. 1981. Cochlear abnormalities in Alport's syndrome. Arch. Otolarynogol. 107: 340-349.
    • (1981) Arch. Otolarynogol. , vol.107 , pp. 340-349
    • Johnsson, L.-G.1    Arenberg, I.K.2
  • 22
    • 0026740928 scopus 로고
    • Distribution of the al and α2 chains of collagen IV and of collagens V and VI in Alport syndrome
    • Kashtan, C.E. and Y. Kim. 1992. Distribution of the al and α2 chains of collagen IV and of collagens V and VI in Alport syndrome. Kidney Int. 42: 115-126.
    • (1992) Kidney Int. , vol.42 , pp. 115-126
    • Kashtan, C.E.1    Kim, Y.2
  • 24
    • 0026709652 scopus 로고
    • Evidence for separate networks of classical and novel basement membrane collagen
    • Kleppel, M.M., W.W. Fan, H.I. Cheong, and A.F. Michael. 1992. Evidence for separate networks of classical and novel basement membrane collagen. J. Biol. Chem. 267: 4137-4142.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4137-4142
    • Kleppel, M.M.1    Fan, W.W.2    Cheong, H.I.3    Michael, A.F.4
  • 25
    • 0024409025 scopus 로고
    • Inactivating the β2-microglobulin locus in mouse embryonic stem cells by homologous recombination
    • Koller, B.H. and O. Smithies. 1989. Inactivating the β2-microglobulin locus in mouse embryonic stem cells by homologous recombination. Proc. Natl. Acad. Sci. 86: 8932-8935.
    • (1989) Proc. Natl. Acad. Sci. , vol.86 , pp. 8932-8935
    • Koller, B.H.1    Smithies, O.2
  • 26
    • 0028151407 scopus 로고
    • Complete primary structure of the human type IV collagen α4(IV) chain. Comparison with structure and expression of the other α(IV) chains
    • Leinonen, A., M. Mariyama, T. Mochizuki, K. Tryggvason, and S. Reeders. 1994. Complete primary structure of the human type IV collagen α4(IV) chain. Comparison with structure and expression of the other α(IV) chains. J. Biol. Chem. 269: 26172-26177.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26172-26177
    • Leinonen, A.1    Mariyama, M.2    Mochizuki, T.3    Tryggvason, K.4    Reeders, S.5
  • 28
    • 0018899370 scopus 로고
    • Fibronectin as a marker for the glomerular mesangium in immunohistology of kidney biopsies
    • Linder, E., A. Miettinen, and I. Törnroth. 1980. Fibronectin as a marker for the glomerular mesangium in immunohistology of kidney biopsies. Lab. Invest. 42: 70-75.
    • (1980) Lab. Invest. , vol.42 , pp. 70-75
    • Linder, E.1    Miettinen, A.2    Törnroth, I.3
  • 29
    • 0022508463 scopus 로고
    • Basement membrane components produced by a mouse ascites teratocarcinoma TB 24: Analysis with monoclonal and polyclonal antibodies
    • Ljubimov, A.V., A.V. Afanasjeva, L.V. Litvinova, and V.M. Senin. 1986. Basement membrane components produced by a mouse ascites teratocarcinoma TB 24: Analysis with monoclonal and polyclonal antibodies. Exp. Cell Res. 165: 530-540.
    • (1986) Exp. Cell Res. , vol.165 , pp. 530-540
    • Ljubimov, A.V.1    Afanasjeva, A.V.2    Litvinova, L.V.3    Senin, V.M.4
  • 30
    • 0024327913 scopus 로고
    • Glomerular localization of type III collagen in human kidney disease
    • Maki, S. 1989. Glomerular localization of type III collagen in human kidney disease. Kidney Int. 35: 1203-1211.
    • (1989) Kidney Int. , vol.35 , pp. 1203-1211
    • Maki, S.1
  • 31
    • 0024465455 scopus 로고
    • Amino acid sequence of mouse nidogen, a multidomain basement membrane protein with binding activity for laminin, collagen IV cells
    • Mann, K., R. Deutzmann, M. Admailley, R. Timpl, L. Raimondi, Y. Yamada, T. Pan, D. Conway, and M.-L. Chu. 1989. Amino acid sequence of mouse nidogen, a multidomain basement membrane protein with binding activity for laminin, collagen IV cells. EMBO J. 8: 65-72.
    • (1989) EMBO J. , vol.8 , pp. 65-72
    • Mann, K.1    Deutzmann, R.2    Admailley, M.3    Timpl, R.4    Raimondi, L.5    Yamada, Y.6    Pan, T.7    Conway, D.8    Chu, M.-L.9
  • 32
    • 0028106032 scopus 로고
    • Complete primary structure of the human α3(IV) collagen chain. Coexpression of the α3(IV) and α4(IV) collagen chains in human tissues
    • Mariyama, M., A. Leinonen, T. Mochizuki, K. Tryggvason, and S.T. Reeders. 1994. Complete primary structure of the human α3(IV) collagen chain. Coexpression of the α3(IV) and α4(IV) collagen chains in human tissues. J. Biol. Chem. 269: 23013-23017.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23013-23017
    • Mariyama, M.1    Leinonen, A.2    Mochizuki, T.3    Tryggvason, K.4    Reeders, S.T.5
  • 33
    • 0028171098 scopus 로고
    • Collagen IV α3, α4, and α5 chains in rodent basal lamina: Sequence, distribution, association with laminins, and developmental switches
    • Miner, J.H. and J.R. Sanes. 1994. Collagen IV α3, α4, and α5 chains in rodent basal lamina: Sequence, distribution, association with laminins, and developmental switches. J. Cell Biol. 127: 879-891.
    • (1994) J. Cell Biol. , vol.127 , pp. 879-891
    • Miner, J.H.1    Sanes, J.R.2
  • 35
    • 0024549762 scopus 로고
    • The complete primary structure for the alpha-1 chain of mouse collagen IV. Differential evolution of collagen IV domains
    • Muthukumaran, G., B. Blumberg, and M. Kurkinen. 1989. The complete primary structure for the alpha-1 chain of mouse collagen IV. Differential evolution of collagen IV domains. J. Biol. Chem. 264: 6310-6317.
    • (1989) J. Biol. Chem. , vol.264 , pp. 6310-6317
    • Muthukumaran, G.1    Blumberg, B.2    Kurkinen, M.3
  • 36
    • 0015416693 scopus 로고
    • The etiology of deafness in Alport's syndrome
    • Myers, G.J. and H.R. Tyler. 1972. The etiology of deafness in Alport's syndrome. Arch. Otolaryng. 96: 333-340.
    • (1972) Arch. Otolaryng. , vol.96 , pp. 333-340
    • Myers, G.J.1    Tyler, H.R.2
  • 38
    • 0029098578 scopus 로고
    • Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies
    • Ninomiya, Y., M. Kagawa, K.-I. Iyama, I. Naito, Y. Kishiro, J.M. Seyer, T. Sugimoto, and Y. Sado. 1995. Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies. J. Cell Biol. 130: 1219-1229.
    • (1995) J. Cell Biol. , vol.130 , pp. 1219-1229
    • Ninomiya, Y.1    Kagawa, M.2    Iyama, K.-I.3    Naito, I.4    Kishiro, Y.5    Seyer, J.M.6    Sugimoto, T.7    Sado, Y.8
  • 39
    • 0023796319 scopus 로고
    • Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan
    • Noonan, D.M., E.A. Horigan, S.R. Ledbetter, G. Vogeli, M. Sasaki, Y. Yamada, and J.R. Hassell. 1988. Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan. J. Biol. Chem. 263: 16379-16387.
    • (1988) J. Biol. Chem. , vol.263 , pp. 16379-16387
    • Noonan, D.M.1    Horigan, E.A.2    Ledbetter, S.R.3    Vogeli, G.4    Sasaki, M.5    Yamada, Y.6    Hassell, J.R.7
  • 40
    • 0023669148 scopus 로고
    • Cell lineage ablation in transgenic mice by cell specific expression of a toxin gene
    • Palmiter, R.D., R.R. Behringer, C.J. Quaife, I.H. Maxwell, and R.L. Brinster. 1987. Cell lineage ablation in transgenic mice by cell specific expression of a toxin gene. Cell 50: 435-443.
    • (1987) Cell , vol.50 , pp. 435-443
    • Palmiter, R.D.1    Behringer, R.R.2    Quaife, C.J.3    Maxwell, I.H.4    Brinster, R.L.5
  • 41
    • 0023938748 scopus 로고
    • Local embryonic matrices determine region-specific phenotypes in neural crest cells
    • Perris, R., Y. von Boxberg, and J. Lofberg. 1988. Local embryonic matrices determine region-specific phenotypes in neural crest cells. Science 241: 86-89.
    • (1988) Science , vol.241 , pp. 86-89
    • Perris, R.1    Von Boxberg, Y.2    Lofberg, J.3
  • 43
    • 0025010542 scopus 로고
    • Molecular heterogeneity of basal laminae: Isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere
    • Sanes, J.R., E. Engvall, R. Butkowski, and D.D. Hunter. 1990. Molecular heterogeneity of basal laminae: Isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J. Cell Biol. 111: 1685-1699.
    • (1990) J. Cell Biol. , vol.111 , pp. 1685-1699
    • Sanes, J.R.1    Engvall, E.2    Butkowski, R.3    Hunter, D.D.4
  • 44
    • 0023657117 scopus 로고
    • The laminin B2 chain has a multidomain structure homologous to the B1 chain
    • Sasaki, M. and Y. Yamada. 1987. The laminin B2 chain has a multidomain structure homologous to the B1 chain. J. Biol. Chem. 262: 17111-17117.
    • (1987) J. Biol. Chem. , vol.262 , pp. 17111-17117
    • Sasaki, M.1    Yamada, Y.2
  • 45
    • 0042383817 scopus 로고
    • Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats
    • Sasaki, M., S. Kato, K. Kohno, G.R. Martin, and Y. Yamada. 1987. Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats. Proc. Natl. Acad. Sci. 84: 935-939.
    • (1987) Proc. Natl. Acad. Sci. , vol.84 , pp. 935-939
    • Sasaki, M.1    Kato, S.2    Kohno, K.3    Martin, G.R.4    Yamada, Y.5
  • 46
    • 0023753669 scopus 로고
    • Identification of the Goodpasture antigen as the α3(IV) chain of collagen IV
    • Saus, J., J. Wieslander, J.P.M. Langeveld, S. Quinoes, and B.G. Hudson. 1988. Identification of the Goodpasture antigen as the α3(IV) chain of collagen IV. J. Biol. Chem. 263: 13374-13380.
    • (1988) J. Biol. Chem. , vol.263 , pp. 13374-13380
    • Saus, J.1    Wieslander, J.2    Langeveld, J.P.M.3    Quinoes, S.4    Hudson, B.G.5
  • 48
    • 0025786161 scopus 로고
    • Control of mammary epithelial differentiation: Basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity
    • Streuli, C.H., N. Bailey, and M.J. Bissel. 1991. Control of mammary epithelial differentiation: Basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity. J. Cell. Biol. 115: 1383-1395.
    • (1991) J. Cell. Biol. , vol.115 , pp. 1383-1395
    • Streuli, C.H.1    Bailey, N.2    Bissel, M.J.3
  • 49
    • 0028080793 scopus 로고
    • The genes COL4A5 and COL4A6, coding for basement membrane collagen chains α5(IV) and α6(IV), are located head-to-head in close proximity on human chromosome Xq22 and COL4A6 is transcribed from two alternative promoters
    • Sugimoto, M., T. Oohashi, and Y. Ninomiya. 1994. The genes COL4A5 and COL4A6, coding for basement membrane collagen chains [α5(IV) and α6(IV), are located head-to-head in close proximity on human chromosome Xq22 and COL4A6 is transcribed from two alternative promoters. Proc. Natl. Acad. Sci. 91: 11679-11683.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 11679-11683
    • Sugimoto, M.1    Oohashi, T.2    Ninomiya, Y.3
  • 50
    • 0027279422 scopus 로고
    • Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo
    • Thomas, T. and M. Dziadek. 1993. Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo. Exp. Cell Res. 208: 54-67.
    • (1993) Exp. Cell Res. , vol.208 , pp. 54-67
    • Thomas, T.1    Dziadek, M.2
  • 52
    • 0023190874 scopus 로고
    • Samoyed hereditary glomerulopathy: Immunohistochemical staining of basement membranes of kidney for laminin, collagen type IV, fibronectin, and Goodpasture antigen, and correlation with electron microscopy of glomerular capillary basement membranes
    • Thomer, P., B. Jansen, R. Baumal, V.E. Valli, and A. Goldberger. 1987. Samoyed hereditary glomerulopathy: Immunohistochemical staining of basement membranes of kidney for laminin, collagen type IV, fibronectin, and Goodpasture antigen, and correlation with electron microscopy of glomerular capillary basement membranes. Lab. Invest. 56: 435.
    • (1987) Lab. Invest. , vol.56 , pp. 435
    • Thomer, P.1    Jansen, B.2    Baumal, R.3    Valli, V.E.4    Goldberger, A.5
  • 53
    • 0024558106 scopus 로고
    • Structure and biological activity of basement membrane proteins
    • Timpl, R. 1989. Structure and biological activity of basement membrane proteins. Eur. J. Biochem. 180: 487-5042.
    • (1989) Eur. J. Biochem. , vol.180 , pp. 487-5042
    • Timpl, R.1
  • 54
    • 0019781637 scopus 로고
    • A network model for the organizaiton of type IV collagen molecules in basement membranes
    • Timpl, R., H. Wiedemann, V. van Delden, H. Furthmayr, and K. Kuhn. 1981. A network model for the organizaiton of type IV collagen molecules in basement membranes. Eur. J. Biochem. 120: 203-211.
    • (1981) Eur. J. Biochem. , vol.120 , pp. 203-211
    • Timpl, R.1    Wiedemann, H.2    Van Delden, V.3    Furthmayr, H.4    Kuhn, K.5
  • 55
    • 0029073116 scopus 로고
    • Differential expression of laminin polypeptides in developing and adult human kidney
    • Virtanen, I., L. Laitinen, and M. Korhonen. 1995. Differential expression of laminin polypeptides in developing and adult human kidney. J. Histochem. and Cytochem. 43: 621-628.
    • (1995) J. Histochem. and Cytochem. , vol.43 , pp. 621-628
    • Virtanen, I.1    Laitinen, L.2    Korhonen, M.3
  • 57
    • 0025672645 scopus 로고
    • Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diptheria toxin A-fragment gene in negative selection
    • Yagi, T., Y. Ikawa, Y. Shigetani, N. Takeda, I. Mabuchi, T. Yamamoto, and S. Aizawa. 1990. Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diptheria toxin A-fragment gene in negative selection. Proc. Natl. Acad. Sci. 87: 9918-9922.
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 9918-9922
    • Yagi, T.1    Ikawa, Y.2    Shigetani, Y.3    Takeda, N.4    Mabuchi, I.5    Yamamoto, T.6    Aizawa, S.7
  • 59
    • 0028331927 scopus 로고
    • Canine X chromosome-linked hereditary nephritis: A genetic model for human X-linked hereditary nephritis resulting from a single base mutation in the gene encoding α5 chain of collagen type IV
    • Zheng, K., P.S. Thomer, P. Marrano, R. Baumal, and R.R. McInnis. 1994. Canine X chromosome-linked hereditary nephritis: A genetic model for human X-linked hereditary nephritis resulting from a single base mutation in the gene encoding α5 chain of collagen type IV. Proc. Natl. Acad. Sci. 91: 3989-3993.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 3989-3993
    • Zheng, K.1    Thomer, P.S.2    Marrano, P.3    Baumal, R.4    McInnis, R.R.5
  • 60
    • 0026063744 scopus 로고
    • A single base mutation in the α5(IV) collagen chain converting a conserved cysteine to serine in Alport syndrome
    • Zhou, J., D.F. Barker, S.L. Hostikka, M.C. Gregory, C.L. Atkin, and K. Tryggvason. 1991. A single base mutation in the α5(IV) collagen chain converting a conserved cysteine to serine in Alport syndrome. Genomics 9: 10-18.
    • (1991) Genomics , vol.9 , pp. 10-18
    • Zhou, J.1    Barker, D.F.2    Hostikka, S.L.3    Gregory, M.C.4    Atkin, C.L.5    Tryggvason, K.6
  • 61
    • 0027485643 scopus 로고
    • Deletion of the paired α5(IV) and α6(IV) collagen genes in inherited smooth muscle tumors
    • Zhou, J., T. Mochizuki, H. Smeets, C. Antignac, P. Laurila, A. de Paepe, and K. Tryggvason. 1993. Deletion of the paired α5(IV) and α6(IV) collagen genes in inherited smooth muscle tumors. Science 261: 1167-1169.
    • (1993) Science , vol.261 , pp. 1167-1169
    • Zhou, J.1    Mochizuki, T.2    Smeets, H.3    Antignac, C.4    Laurila, P.5    De Paepe, A.6    Tryggvason, K.7
  • 62
    • 0028353676 scopus 로고
    • Deletions in the COL4A5 collagen gene in X-linked Alport syndrome. Characterization of the pathological transcripts in nonrenal cells and correlation with disease expression
    • Zhou, K. Tryggvason, J.P. Grunfeld, M. Broyer, and M.C. Gubler. 1994. Deletions in the COL4A5 collagen gene in X-linked Alport syndrome. Characterization of the pathological transcripts in nonrenal cells and correlation with disease expression. J. Clin. Invest. 93: 1195-1207.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1195-1207
    • Zhou1    Tryggvason, K.2    Grunfeld, J.P.3    Broyer, M.4    Gubler, M.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.