ImKTx88, a novel selective Kv1.3 channel blocker derived from the scorpion Isometrus maculates

Toxicon

Volumn 57, Issue 2, 2011, Pages 348-355

  Han, Song ^a,b   Hu, Youtian ^b   Zhang, Ruhong ^b   Yi, Hong ^b   Wei, Jingjing ^b   Wu, Yingliang ^b   Cao, Zhijian ^b   Li, Wenxin ^b   He, Xiaohua ^a  

^a WUHAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

ImKTx88; Isometrus maculates; Kv1.3 channel; Scorpion toxin

Indexed keywords

CYSTEINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.1; POTASSIUM CHANNEL KV1.2; POTASSIUM CHANNEL KV1.3; RECOMBINANT ISOMETRUS MACULATES POTASSIUM CHANNEL TOXIN 88; SCORPION VENOM; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DNA LIBRARY; DRUG DESIGN; DRUG PURIFICATION; DRUG TARGETING; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; IC 50; ISOMETRUS MACULATES; NONHUMAN; PHYLOGENETIC TREE; POISONOUS SCORPION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; ELECTROPHYSIOLOGY; GENE LIBRARY; HEK293 CELLS; HUMANS; KV1.3 POTASSIUM CHANNEL; PATCH-CLAMP TECHNIQUES; RECOMBINANT FUSION PROTEINS; SCORPION VENOMS; SCORPIONS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN;

SCORPIONES;

EID: 79251630565     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.12.015     Document Type: Article

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