Potassium channels in T lymphocytes: Toxins to therapeutic immunosuppressants

Toxicon

Volumn 39, Issue 9, 2001, Pages 1269-1276

  George Chandy, K ^a   Cahalan, Michael ^a   Pennington, Michael ^b   Norton, Raymond S ^c   Wulff, Heike ^a   Gutman, George A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Bachem Holding AG   (Switzerland)

^c CSIRO   (Australia)

Author keywords

Drug design; Potassium channels; Toxins

Indexed keywords

1 BENZYL 1,4 DIHYDRO 4 PENTYLIMINOQUINOLINE; 4 BENZHYDRYLOXYMETHYL 1 [3 (4 METHOXYPHENYL)PROPYL]PIPERIDINE; AGITOXIN 2; BUNODOSOMA GRANULIFERA TOXIN; CHARYBDOTOXIN; CLOTRIMAZOLE; CORREOLIDE; DILTIAZEM; ECONAZOLE; HONGOTOXIN; IMMUNOSUPPRESSIVE AGENT; KALIOTOXIN; KETOCONAZOLE; MARGATOXIN; MAUROTOXIN; METHANE NANOMOLAR INHIBITOR 3; METHANE NANOMOLAR INHIBITOR 34; NIFEDIPINE; NIMODIPINE; NITRENDIPINE; NOXIUSTOXIN; PHENYLOXOAZAPROPYLCYCLOALKANE; POTASSIUM CHANNEL; QUININE; SCORPION VENOM; SEA ANEMONE TOXIN; STICHODACTYLA HELIANTHUS TOXIN; SULFAMIDBENZAMIDOINDANE; UNCLASSIFIED DRUG; VERAPAMIL;

DRUG DESIGN; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SHORT SURVEY; T LYMPHOCYTE; TOXIN STRUCTURE;

ANIMALS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; T-LYMPHOCYTES; TOXINS, BIOLOGICAL;

ACTINIARIA; ANEMONE; BUNODOSOMA GRANULIFERA; CINCHONA PUBESCENS; HELIANTHUS; SCORPIONES; STICHODACTYLA HELIANTHUS;

EID: 0034987611     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(01)00120-9     Document Type: Short Survey

References (62)

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14. 1H NMR analysis using a nano-NMR probe
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46. 24
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57. Peptidyl inhibitors of Shaker-type Kv1 channels elicit twitches in guinea pig ileum by blocking Kv1.1 at enteric nervous system and enhancing acetylcholine release
58. Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone
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60. WIN 17317-3, a new high-affinity probe for voltage-gated sodium channels
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