K+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom

Biochemical Journal

Volumn 385, Issue 1, 2005, Pages 95-104

  Mouhat, Stéphanie ^a   Visan, Violeta ^b   Ananthakrishnan, S ^c   Wulff, Heike ^c   Andreotti, Nicolas ^a   Grissmer, Stephan ^b   Darbon, Hervé ^d   De Waard, Michel ^e   Sabatier, Jean Marc ^a,f  

^a Laboratoire Cellpep SA   (France)

^b UNIVERSITY OF ULM   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Centre National de la Recherche Scientifique   (France)

^e CEA GRENOBLE   (France)

^f ICNRS FRE 2738   (France)

Author keywords

Ca2+ activated K+ channel; OSK1; Peptide synthesis; Scorpion toxin; Voltage gated K+ channel

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CROSSLINKING; DATA REDUCTION; ELECTRIC POTENTIAL; SULFUR COMPOUNDS; SYNTHESIS (CHEMICAL);

IMMUNOSUPPRESSIVE DRUGS; LETHALITY; MICE; SOLID-PHASE CHEMICAL SYNTHESIS;

DRUG PRODUCTS;

CALCIUM ACTIVATED POTASSIUM CHANNEL; NEUROTOXIN; OSK1 TOXIN; POTASSIUM CHANNEL; SCORPION VENOM; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; GENE MUTATION; LD 50; MOLECULAR INTERACTION; MOUSE; NEUROTOXICITY; NONHUMAN; ORTHOCHIRUS SCROBICULOSUS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCORPION; STRUCTURE ANALYSIS; TOXIN ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; HUMANS; INHIBITORY CONCENTRATION 50; INJECTIONS, INTRAVENTRICULAR; LETHAL DOSE 50; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; SCORPION VENOMS; SCORPIONS; TOXINS, BIOLOGICAL;

ANIMALIA; ORTHOCHIRUS; ORTHOCHIRUS SCROBICULOSUS; SCORPIONES;

EID: 12744253747     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041379     Document Type: Article

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