-
1
-
-
33750595669
-
The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae
-
Abdel-Mottaleb Y., Clynen E., Jalali A., Bosmans F., Vatanpour H., Schoofs L., and Tytgat J. The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae. FEBS Lett. 580 26 (2006) 6254-6258
-
(2006)
FEBS Lett.
, vol.580
, Issue.26
, pp. 6254-6258
-
-
Abdel-Mottaleb, Y.1
Clynen, E.2
Jalali, A.3
Bosmans, F.4
Vatanpour, H.5
Schoofs, L.6
Tytgat, J.7
-
2
-
-
30644463697
-
A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily
-
Abdel-Mottaleb Y., Coronas F.V., de Roodt A.R., Possani L.D., and Tytgat J. A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily. FEBS Lett. 580 2 (2006) 592-596
-
(2006)
FEBS Lett.
, vol.580
, Issue.2
, pp. 592-596
-
-
Abdel-Mottaleb, Y.1
Coronas, F.V.2
de Roodt, A.R.3
Possani, L.D.4
Tytgat, J.5
-
3
-
-
0032439746
-
Purification and primary structure of low molecular mass peptides from scorpion (Buthus sindicus) venom
-
Ali S.A., Stoeva S., Schutz J., Kayed R., Abassi A., Zaidi Z.H., and Voelter W. Purification and primary structure of low molecular mass peptides from scorpion (Buthus sindicus) venom. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 121 4 (1998) 323-332
-
(1998)
Comp. Biochem. Physiol. A Mol. Integr. Physiol.
, vol.121
, Issue.4
, pp. 323-332
-
-
Ali, S.A.1
Stoeva, S.2
Schutz, J.3
Kayed, R.4
Abassi, A.5
Zaidi, Z.H.6
Voelter, W.7
-
4
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
-
Altschul S.F., Madden T.L., Schuffer A.A., Zhang J., Miller W., and Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucl. Acids Res. 25 (1997) 3389-3402
-
(1997)
Nucl. Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schuffer, A.A.3
Zhang, J.4
Miller, W.5
Lipman, D.J.6
-
5
-
-
0035863820
-
+ channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation
-
+ channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation. J. Immunol. 166 2 (2001) 936-944
-
(2001)
J. Immunol.
, vol.166
, Issue.2
, pp. 936-944
-
-
Beeton, C.1
Barbaria, J.2
Giraud, P.3
Devaux, J.4
Benoliel, A.M.5
Gola, M.6
Sabatier, J.M.7
Bernard, D.8
Crest, M.9
Beraud, E.10
-
6
-
-
0037646521
-
A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes
-
Beeton C., Wulff H., Singh S., Botsko S., Crossley G., Gutman G.A., Cahalan M.D., Pennington M., and Chandy K.G. A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes. J. Biol. Chem. 278 11 (2003) 9928-9937
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.11
, pp. 9928-9937
-
-
Beeton, C.1
Wulff, H.2
Singh, S.3
Botsko, S.4
Crossley, G.5
Gutman, G.A.6
Cahalan, M.D.7
Pennington, M.8
Chandy, K.G.9
-
7
-
-
20144366005
-
Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases
-
Beeton C., Pennington M.W., Wulff H., Singh S., Nugent D., Crossley G., Khaytin I., Calabresi P.A., Chen C.Y., Gutman G.A., and Chandy K.G. Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases. Mol. Pharmacol. 67 4 (2005) 1369-1381
-
(2005)
Mol. Pharmacol.
, vol.67
, Issue.4
, pp. 1369-1381
-
-
Beeton, C.1
Pennington, M.W.2
Wulff, H.3
Singh, S.4
Nugent, D.5
Crossley, G.6
Khaytin, I.7
Calabresi, P.A.8
Chen, C.Y.9
Gutman, G.A.10
Chandy, K.G.11
-
8
-
-
0026567123
-
+ channels characterized from Androctonus mauretanicus mauretanicus venom
-
+ channels characterized from Androctonus mauretanicus mauretanicus venom. J. Biol. Chem. 267 3 (1992) 1640-1647
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.3
, pp. 1640-1647
-
-
Crest, M.1
Jacquet, G.2
Gola, M.3
Zerrouk, H.4
Benslimane, A.5
Rochat, H.6
Mansuelle, P.7
Martin-Eauclaire, M.F.8
-
9
-
-
6544276937
-
On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures
-
Dauplais M., Lecoq A., Song J., Cotton J., Jamin N., Gilquin B., Roumestand C., Vita C., de Medeiros C.L., Rowan E.G., Harvey A.L., and Menez A. On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures. J. Biol. Chem. 272 7 (1997) 4302-4309
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.7
, pp. 4302-4309
-
-
Dauplais, M.1
Lecoq, A.2
Song, J.3
Cotton, J.4
Jamin, N.5
Gilquin, B.6
Roumestand, C.7
Vita, C.8
de Medeiros, C.L.9
Rowan, E.G.10
Harvey, A.L.11
Menez, A.12
-
11
-
-
22844448219
-
A variable residue in the pore of Kv1 channels is critical for the high affinity of blockers from sea anemones and scorpions
-
Gilquin B., Braud S., Eriksson M.A., Roux B., Bailey T.D., Priest B.T., Garcia M.L., Menez A., and Gasparini S. A variable residue in the pore of Kv1 channels is critical for the high affinity of blockers from sea anemones and scorpions. J. Biol. Chem. 280 29 (2005) 27093-27102
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.29
, pp. 27093-27102
-
-
Gilquin, B.1
Braud, S.2
Eriksson, M.A.3
Roux, B.4
Bailey, T.D.5
Priest, B.T.6
Garcia, M.L.7
Menez, A.8
Gasparini, S.9
-
12
-
-
85047696278
-
Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom
-
Huys I., Dyason K., Waelkens E., Verdonck F., van Zyl J., du Plessis J., Muller G.J., van der Walt J., Clynen E., Schoofs L., and Tytgat J. Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom. Eur. J. Biochem. 269 7 (2002) 1854-1865
-
(2002)
Eur. J. Biochem.
, vol.269
, Issue.7
, pp. 1854-1865
-
-
Huys, I.1
Dyason, K.2
Waelkens, E.3
Verdonck, F.4
van Zyl, J.5
du Plessis, J.6
Muller, G.J.7
van der Walt, J.8
Clynen, E.9
Schoofs, L.10
Tytgat, J.11
-
13
-
-
1642546220
-
+ and HERG currents
-
+ and HERG currents. Biochem. J. 378 Pt 3 (2004) 745-752
-
(2004)
Biochem. J.
, vol.378
, Issue.PART 3
, pp. 745-752
-
-
Huys, I.1
Xu, C.Q.2
Wang, C.Z.3
Vacher, H.4
Martin-Eauclaire, M.F.5
Chi, C.W.6
Tytgat, J.7
-
14
-
-
22544480319
-
+ channels
-
+ channels. FEBS Lett. 579 19 (2005) 4181-4186
-
(2005)
FEBS Lett.
, vol.579
, Issue.19
, pp. 4181-4186
-
-
Jalali, A.1
F. Bosmans, M.2
Amininasab, E.3
Clynen, E.4
Cuypers, A.5
Zaremirakabadi, M.N.6
Sarbolouki, L.7
Schoofs, H.8
Vatanpour9
Tytgat, J.10
-
15
-
-
0031036241
-
Three-dimensional structure of toxin OSK1 from Orthochirus scrobiculosus scorpion venom
-
Jaravine V.A., Nolde D.E., Reibarkh M.J., Korolkova Y.V., Kozlov S.A., Pluzhnikov K.A., Grishin E.V., and Arseniev A.S. Three-dimensional structure of toxin OSK1 from Orthochirus scrobiculosus scorpion venom. Biochemistry 36 6 (1997) 1223-1232
-
(1997)
Biochemistry
, vol.36
, Issue.6
, pp. 1223-1232
-
-
Jaravine, V.A.1
Nolde, D.E.2
Reibarkh, M.J.3
Korolkova, Y.V.4
Kozlov, S.A.5
Pluzhnikov, K.A.6
Grishin, E.V.7
Arseniev, A.S.8
-
16
-
-
0032483810
-
ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide
-
Kalman K., Pennington M.W., Lanigan M.D., Nguyen A., Rauer H., Mahnir V., Paschetto K., Kem W.R., Grissmer S., Gutman G.A., Christian E.P., Cahalan M.D., Norton R.S., and Chandy K.G. ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide. J. Biol. Chem. 273 49 (1998) 32697-32707
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.49
, pp. 32697-32707
-
-
Kalman, K.1
Pennington, M.W.2
Lanigan, M.D.3
Nguyen, A.4
Rauer, H.5
Mahnir, V.6
Paschetto, K.7
Kem, W.R.8
Grissmer, S.9
Gutman, G.A.10
Christian, E.P.11
Cahalan, M.D.12
Norton, R.S.13
Chandy, K.G.14
-
17
-
-
0348062818
-
The SWISS-MODEL Repository of annotated three-dimensional protein structure homology models
-
Kopp J., and Schwede T. The SWISS-MODEL Repository of annotated three-dimensional protein structure homology models. Nucl. Acids Res. 32 Database issue (2004) D230-D234
-
(2004)
Nucl. Acids Res.
, vol.32
, Issue.Database issue
-
-
Kopp, J.1
Schwede, T.2
-
18
-
-
0029881007
-
MOLMOL: a program for display and analysis of macromolecular structures
-
29-32
-
Koradi R., Billeter M., and Wuthrich K. MOLMOL: a program for display and analysis of macromolecular structures. J. Mol. Graph. 14 1 (1996) 51-55 29-32
-
(1996)
J. Mol. Graph.
, vol.14
, Issue.1
, pp. 51-55
-
-
Koradi, R.1
Billeter, M.2
Wuthrich, K.3
-
19
-
-
34248583581
-
Isolation of the first toxin from the scorpion Buthus occitanus israelis showing preference for Shaker potassium channels
-
Kozminsky-Atias A., Somech E., and Zilberberg N. Isolation of the first toxin from the scorpion Buthus occitanus israelis showing preference for Shaker potassium channels. FEBS Lett. (2007)
-
(2007)
FEBS Lett.
-
-
Kozminsky-Atias, A.1
Somech, E.2
Zilberberg, N.3
-
20
-
-
0028567150
-
The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom
-
Laraba-Djebari F., Legros C., Crest M., Ceard B., Romi R., Mansuelle P., Jacquet G., van Rietschoten J., Gola M., and Rochat H. The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom. J. Biol. Chem. 269 52 (1994) 32835-32843
-
(1994)
J. Biol. Chem.
, vol.269
, Issue.52
, pp. 32835-32843
-
-
Laraba-Djebari, F.1
Legros, C.2
Crest, M.3
Ceard, B.4
Romi, R.5
Mansuelle, P.6
Jacquet, G.7
van Rietschoten, J.8
Gola, M.9
Rochat, H.10
-
21
-
-
2942511454
-
VKCDB: voltage-gated potassium channel database
-
Li B., and Gallin W.J. VKCDB: voltage-gated potassium channel database. BMC Bioinformat. 5 (2004) 3
-
(2004)
BMC Bioinformat.
, vol.5
, pp. 3
-
-
Li, B.1
Gallin, W.J.2
-
22
-
-
33745249950
-
Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae
-
Maertens C., Cuypers E., Amininasab M., Jalali A., Vatanpour H., and Tytgat J. Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae. Mol. Pharmacol. 70 1 (2006) 405-414
-
(2006)
Mol. Pharmacol.
, vol.70
, Issue.1
, pp. 405-414
-
-
Maertens, C.1
Cuypers, E.2
Amininasab, M.3
Jalali, A.4
Vatanpour, H.5
Tytgat, J.6
-
23
-
-
0033990613
-
KTX3, the kaliotoxin from Buthus occitanus tunetanus scorpion venom: one of an extensive family of peptidyl ligands of potassium channels
-
Meki A., Mansuelle P., Laraba-Djebari F., Oughideni R., Rochat H., and Martin-Eauclaire M.F. KTX3, the kaliotoxin from Buthus occitanus tunetanus scorpion venom: one of an extensive family of peptidyl ligands of potassium channels. Toxicon 38 1 (2000) 105-111
-
(2000)
Toxicon
, vol.38
, Issue.1
, pp. 105-111
-
-
Meki, A.1
Mansuelle, P.2
Laraba-Djebari, F.3
Oughideni, R.4
Rochat, H.5
Martin-Eauclaire, M.F.6
-
25
-
-
1642464613
-
Diversity of folds in animal toxins acting on ion channels
-
Mouhat S., Jouirou B., Mosbah A., De Waard M., and Sabatier J.M. Diversity of folds in animal toxins acting on ion channels. Biochem. J. 378 Pt 3 (2004) 717-726
-
(2004)
Biochem. J.
, vol.378
, Issue.PART 3
, pp. 717-726
-
-
Mouhat, S.1
Jouirou, B.2
Mosbah, A.3
De Waard, M.4
Sabatier, J.M.5
-
26
-
-
12744253747
-
+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom
-
+ channel types targeted by synthetic OSK1, a toxin from Orthochirus scrobiculosus scorpion venom. Biochem. J. 385 Pt 1 (2005) 95-104
-
(2005)
Biochem. J.
, vol.385
, Issue.PART 1
, pp. 95-104
-
-
Mouhat, S.1
Visan, V.2
Ananthakrishnan, S.3
Wulff, H.4
Andreotti, N.5
Grissmer, S.6
Darbon, H.7
De Waard, M.8
Sabatier, J.M.9
-
27
-
-
0023989064
-
Improved tools for biological sequence comparison
-
Pearson W.R., and Lipman D.J. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85 8 (1988) 2444-2448
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, Issue.8
, pp. 2444-2448
-
-
Pearson, W.R.1
Lipman, D.J.2
-
28
-
-
0034638614
-
Blockage of human T lymphocyte Kv1.3 channels by Pi1, a novel class of scorpion toxin
-
Peter Jr. M., Hajdu P., Varga Z., Damjanovich S., Possani L.D., Panyi G., and Gaspar Jr. R. Blockage of human T lymphocyte Kv1.3 channels by Pi1, a novel class of scorpion toxin. Biochem. Biophys. Res. Commun. 278 1 (2000) 34-37
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, Issue.1
, pp. 34-37
-
-
Peter Jr., M.1
Hajdu, P.2
Varga, Z.3
Damjanovich, S.4
Possani, L.D.5
Panyi, G.6
Gaspar Jr., R.7
-
31
-
-
27544454783
-
Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases
-
Schmitz A., Sankaranarayanan A., Azam P., Schmidt-Lassen K., Homerick D., Hansel W., and Wulff H. Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases. Mol. Pharmacol. 68 5 (2005) 1254-1270
-
(2005)
Mol. Pharmacol.
, vol.68
, Issue.5
, pp. 1254-1270
-
-
Schmitz, A.1
Sankaranarayanan, A.2
Azam, P.3
Schmidt-Lassen, K.4
Homerick, D.5
Hansel, W.6
Wulff, H.7
-
32
-
-
4544232717
-
pH-dependent modulation of Kv1.3 inactivation: role of His399
-
Somodi S., Varga Z., Hajdu P., Starkus J.G., Levy D.I., Gaspar R., and Panyi G. pH-dependent modulation of Kv1.3 inactivation: role of His399. Am. J. Physiol. Cell Physiol. 287 4 (2004) C1067-C1076
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
, Issue.4
-
-
Somodi, S.1
Varga, Z.2
Hajdu, P.3
Starkus, J.G.4
Levy, D.I.5
Gaspar, R.6
Panyi, G.7
-
33
-
-
0024261928
-
Potassium channels expressed from rat brain cDNA have delayed rectifier properties
-
Stuhmer W., Stocker M., Sakmann B., Seeburg P., Baumann A., Grupe A., and Pongs O. Potassium channels expressed from rat brain cDNA have delayed rectifier properties. FEBS Lett. 242 1 (1988) 199-206
-
(1988)
FEBS Lett.
, vol.242
, Issue.1
, pp. 199-206
-
-
Stuhmer, W.1
Stocker, M.2
Sakmann, B.3
Seeburg, P.4
Baumann, A.5
Grupe, A.6
Pongs, O.7
-
34
-
-
0028973231
-
The alpha-dendrotoxin footprint on a mammalian potassium channel
-
Tytgat J., Debont T., Carmeliet E., and Daenens P. The alpha-dendrotoxin footprint on a mammalian potassium channel. J. Biol. Chem. 270 42 (1995) 24776-24781
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.42
, pp. 24776-24781
-
-
Tytgat, J.1
Debont, T.2
Carmeliet, E.3
Daenens, P.4
-
35
-
-
0032753963
-
A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies
-
Tytgat J., Chandy K.G., Garcia M.L., Gutman G.A., Martin-Eauclaire M.F., van der Walt J.J., and Possani L.D. A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies. Trends Pharmacol. Sci. 20 11 (1999) 444-447
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, Issue.11
, pp. 444-447
-
-
Tytgat, J.1
Chandy, K.G.2
Garcia, M.L.3
Gutman, G.A.4
Martin-Eauclaire, M.F.5
van der Walt, J.J.6
Possani, L.D.7
-
36
-
-
2442660257
-
Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators
-
Vennekamp J., Wulff H., Beeton C., Calabresi P.A., Grissmer S., Hansel W., and Chandy K.G. Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators. Mol. Pharmacol. 65 6 (2004) 1364-1374
-
(2004)
Mol. Pharmacol.
, vol.65
, Issue.6
, pp. 1364-1374
-
-
Vennekamp, J.1
Wulff, H.2
Beeton, C.3
Calabresi, P.A.4
Grissmer, S.5
Hansel, W.6
Chandy, K.G.7
-
37
-
-
0036016272
-
K(+) channels as therapeutic drug targets
-
Wickenden A. K(+) channels as therapeutic drug targets. Pharmacol. Ther. 94 1-2 (2002) 157-182
-
(2002)
Pharmacol. Ther.
, vol.94
, Issue.1-2
, pp. 157-182
-
-
Wickenden, A.1
-
38
-
-
0038481183
-
The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS
-
Wulff H., Calabresi P.A., Allie R., Yun S., Pennington M., Beeton C., and Chandy K.G. The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS. J. Clin. Invest. 111 11 (2003) 1703-1713
-
(2003)
J. Clin. Invest.
, vol.111
, Issue.11
, pp. 1703-1713
-
-
Wulff, H.1
Calabresi, P.A.2
Allie, R.3
Yun, S.4
Pennington, M.5
Beeton, C.6
Chandy, K.G.7
-
39
-
-
2942677403
-
Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel
-
Yu K., Fu W., Liu H., Luo X., Chen K.X., Ding J., Shen J., and Jiang H. Computational simulations of interactions of scorpion toxins with the voltage-gated potassium ion channel. Biophys. J. 86 6 (2004) 3542-3555
-
(2004)
Biophys. J.
, vol.86
, Issue.6
, pp. 3542-3555
-
-
Yu, K.1
Fu, W.2
Liu, H.3
Luo, X.4
Chen, K.X.5
Ding, J.6
Shen, J.7
Jiang, H.8
|