-
1
-
-
0037342121
-
Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation
-
Adams C.L., Macleod M.K., James Milner-White E., Aitken R., Garside P., Stott D.I. Complete analysis of the B-cell response to a protein antigen, from in vivo germinal centre formation to 3-D modelling of affinity maturation. Immunology 2003, 108:274-287.
-
(2003)
Immunology
, vol.108
, pp. 274-287
-
-
Adams, C.L.1
Macleod, M.K.2
James Milner-White, E.3
Aitken, R.4
Garside, P.5
Stott, D.I.6
-
2
-
-
0142245596
-
Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone
-
Albesiano E., Messmer B.T., Damle R.N., Allen S.L., Rai K.R., Chiorazzi N. Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone. Blood 2003, 102:3333-3339.
-
(2003)
Blood
, vol.102
, pp. 3333-3339
-
-
Albesiano, E.1
Messmer, B.T.2
Damle, R.N.3
Allen, S.L.4
Rai, K.R.5
Chiorazzi, N.6
-
3
-
-
33846635838
-
Imaging of germinal center selection events during affinity maturation
-
Allen C.D., Okada T., Tang H.L., Cyster J.G. Imaging of germinal center selection events during affinity maturation. Science 2007, 315:528-531.
-
(2007)
Science
, vol.315
, pp. 528-531
-
-
Allen, C.D.1
Okada, T.2
Tang, H.L.3
Cyster, J.G.4
-
4
-
-
0032952261
-
Repertoire shift occurs during the memory maintenance phase of the immune responses and is not affinity-driven
-
Andersson K., Wrammert J., Leanderson T. Repertoire shift occurs during the memory maintenance phase of the immune responses and is not affinity-driven. Scand. J. Immunol. 1999, 49:1-6.
-
(1999)
Scand. J. Immunol.
, vol.49
, pp. 1-6
-
-
Andersson, K.1
Wrammert, J.2
Leanderson, T.3
-
5
-
-
0035871625
-
Increased transcription levels induce higher mutation rates in a hypermutating cell line
-
Bachl J., Carlson C., Gray-Schopfer V., Dessing M., Olsson C. Increased transcription levels induce higher mutation rates in a hypermutating cell line. J. Immunol. 2001, 166:5051-5057.
-
(2001)
J. Immunol.
, vol.166
, pp. 5051-5057
-
-
Bachl, J.1
Carlson, C.2
Gray-Schopfer, V.3
Dessing, M.4
Olsson, C.5
-
6
-
-
0031460776
-
Critical test of hot spot motifs for immunoglobulin hypermutation
-
Bachl J., Steinberg C., Wabl M. Critical test of hot spot motifs for immunoglobulin hypermutation. Eur. J. Immunol. 1997, 27:3398-3403.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 3398-3403
-
-
Bachl, J.1
Steinberg, C.2
Wabl, M.3
-
7
-
-
12744259733
-
Activation-induced deaminase: controversies and open questions
-
Barreto V.M., Ramiro A.R., Nussenzweig M.C. Activation-induced deaminase: controversies and open questions. Trends Immunol. 2005, 26:90-96.
-
(2005)
Trends Immunol.
, vol.26
, pp. 90-96
-
-
Barreto, V.M.1
Ramiro, A.R.2
Nussenzweig, M.C.3
-
8
-
-
1542328859
-
Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo
-
Beale R.C., Petersen-Mahrt S.K., Watt I.N., Harris R.S., Rada C., Neuberger M.S. Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo. J. Mol. Biol. 2004, 337:585-596.
-
(2004)
J. Mol. Biol.
, vol.337
, pp. 585-596
-
-
Beale, R.C.1
Petersen-Mahrt, S.K.2
Watt, I.N.3
Harris, R.S.4
Rada, C.5
Neuberger, M.S.6
-
9
-
-
0023161406
-
Mutation drift and repertoire shift in the maturation of the immune response
-
Berek C., Milstein C. Mutation drift and repertoire shift in the maturation of the immune response. Immunol. Rev. 1987, 96:23-41.
-
(1987)
Immunol. Rev.
, vol.96
, pp. 23-41
-
-
Berek, C.1
Milstein, C.2
-
10
-
-
38349049465
-
Identification of murine B cell lines that undergo somatic hypermutation focused to A:T and G:C residues
-
Bhattacharya P., Grigera F., Rogozin I.B., McCarty T., Morse H.C., Kenter A.L. Identification of murine B cell lines that undergo somatic hypermutation focused to A:T and G:C residues. Eur. J. Immunol. 2008, 38:227-239.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 227-239
-
-
Bhattacharya, P.1
Grigera, F.2
Rogozin, I.B.3
McCarty, T.4
Morse, H.C.5
Kenter, A.L.6
-
11
-
-
0023604840
-
A limited number of B cell lineages generates the heterogeneity of a secondary immune response
-
Blier P.R., Bothwell A. A limited number of B cell lineages generates the heterogeneity of a secondary immune response. J. Immunol. 1987, 139:3996-4006.
-
(1987)
J. Immunol.
, vol.139
, pp. 3996-4006
-
-
Blier, P.R.1
Bothwell, A.2
-
12
-
-
0037388165
-
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
-
Bransteitter R., Pham P., Scharff M.D., Goodman M.F. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:4102-4107.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 4102-4107
-
-
Bransteitter, R.1
Pham, P.2
Scharff, M.D.3
Goodman, M.F.4
-
13
-
-
33745498089
-
DNA repair in antibody somatic hypermutation
-
Casali P., Pal Z., Xu Z., Zan H. DNA repair in antibody somatic hypermutation. Trends Immunol. 2006, 27:313-321.
-
(2006)
Trends Immunol.
, vol.27
, pp. 313-321
-
-
Casali, P.1
Pal, Z.2
Xu, Z.3
Zan, H.4
-
14
-
-
0027932998
-
The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement
-
Chang B., Casali P. The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement. Immunol. Today 1994, 15:367-373.
-
(1994)
Immunol. Today
, vol.15
, pp. 367-373
-
-
Chang, B.1
Casali, P.2
-
15
-
-
52949111532
-
Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line
-
Chezar I., Lobel-Lavi L., Steinitz M., Laskov R. Ongoing somatic hypermutation of the rearranged VH but not of the V-lambda gene in EBV-transformed rheumatoid factor-producing lymphoblastoid cell line. Mol. Immunol. 2008, 46:80-90.
-
(2008)
Mol. Immunol.
, vol.46
, pp. 80-90
-
-
Chezar, I.1
Lobel-Lavi, L.2
Steinitz, M.3
Laskov, R.4
-
16
-
-
33846404877
-
DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse
-
Delbos F., Aoufouchi S., Faili A., Weill J.C., Reynaud C.A. DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse. J. Exp. Med. 2007, 204:17-23.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 17-23
-
-
Delbos, F.1
Aoufouchi, S.2
Faili, A.3
Weill, J.C.4
Reynaud, C.A.5
-
17
-
-
0343484998
-
T cells can induce somatic mutation in B cell receptor-engaged BL2 Burkitt's lymphoma cells independently of CD40-CD40 ligand interactions
-
Denepoux S., Fournier N., Peronne C., Banchereau J., Lebecque S. T cells can induce somatic mutation in B cell receptor-engaged BL2 Burkitt's lymphoma cells independently of CD40-CD40 ligand interactions. J. Immunol. 2000, 164:1306-1313.
-
(2000)
J. Immunol.
, vol.164
, pp. 1306-1313
-
-
Denepoux, S.1
Fournier, N.2
Peronne, C.3
Banchereau, J.4
Lebecque, S.5
-
18
-
-
0031569118
-
Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes
-
Dorner T., Brezinschek H.P., Brezinschek R.I., Foster S.J., Domiati-Saad R., Lipsky P.E. Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes. J. Immunol. 1997, 158:2779-2789.
-
(1997)
J. Immunol.
, vol.158
, pp. 2779-2789
-
-
Dorner, T.1
Brezinschek, H.P.2
Brezinschek, R.I.3
Foster, S.J.4
Domiati-Saad, R.5
Lipsky, P.E.6
-
19
-
-
33748789332
-
Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations
-
Epeldegui M., Hung Y.P., McQuay A., Ambinder R.F., Martinez-Maza O. Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutation-inducing molecules and in the accrual of oncogene mutations. Mol. Immunol. 2007, 44:934-942.
-
(2007)
Mol. Immunol.
, vol.44
, pp. 934-942
-
-
Epeldegui, M.1
Hung, Y.P.2
McQuay, A.3
Ambinder, R.F.4
Martinez-Maza, O.5
-
20
-
-
0036732772
-
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line
-
Faili A., Aoufouchi S., Gueranger Q., Zober C., Leon A., Bertocci B., Weill J.C., Reynaud C.A. AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line. Nat. Immunol. 2002, 3:815-821.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 815-821
-
-
Faili, A.1
Aoufouchi, S.2
Gueranger, Q.3
Zober, C.4
Leon, A.5
Bertocci, B.6
Weill, J.C.7
Reynaud, C.A.8
-
21
-
-
70249093627
-
The concerted action of Msh2 and UNG stimulates somatic hypermutation at A.T base pairs
-
Frieder D., Larijani M., Collins C., Shulman M., Martin A. The concerted action of Msh2 and UNG stimulates somatic hypermutation at A.T base pairs. Mol. Cell Biol. 2009, 29:5148-5157.
-
(2009)
Mol. Cell Biol.
, vol.29
, pp. 5148-5157
-
-
Frieder, D.1
Larijani, M.2
Collins, C.3
Shulman, M.4
Martin, A.5
-
22
-
-
0042441971
-
Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma
-
Gaidano G., Pasqualucci L., Capello D., Berra E., Deambrogi C., Rossi D., Maria Larocca L., Gloghini A., Carbone A., Dalla-Favera R. Aberrant somatic hypermutation in multiple subtypes of AIDS-associated non-Hodgkin lymphoma. Blood 2003, 102:1833-1841.
-
(2003)
Blood
, vol.102
, pp. 1833-1841
-
-
Gaidano, G.1
Pasqualucci, L.2
Capello, D.3
Berra, E.4
Deambrogi, C.5
Rossi, D.6
Maria Larocca, L.7
Gloghini, A.8
Carbone, A.9
Dalla-Favera, R.10
-
23
-
-
33748128977
-
Somatic mutations and activation-induced cytidine deaminase (AID) expression in established rheumatoid factor-producing lymphoblastoid cell line
-
Gil Y., Levy-Nabot S., Steinitz M., Laskov R. Somatic mutations and activation-induced cytidine deaminase (AID) expression in established rheumatoid factor-producing lymphoblastoid cell line. Mol. Immunol. 2007, 44:494-505.
-
(2007)
Mol. Immunol.
, vol.44
, pp. 494-505
-
-
Gil, Y.1
Levy-Nabot, S.2
Steinitz, M.3
Laskov, R.4
-
24
-
-
0023107028
-
Patterns of somatic mutations in immunoglobulin variable genes
-
Golding G.B., Gearhart P.J., Glickman B.W. Patterns of somatic mutations in immunoglobulin variable genes. Genetics 1987, 115:169-176.
-
(1987)
Genetics
, vol.115
, pp. 169-176
-
-
Golding, G.B.1
Gearhart, P.J.2
Glickman, B.W.3
-
25
-
-
0031009483
-
Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers
-
Goyenechea B., Klix N., Yelamos J., Williams G.T., Riddell A., Neuberger M.S., Milstein C. Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers. EMBO J. 1997, 16:3987-3994.
-
(1997)
EMBO J.
, vol.16
, pp. 3987-3994
-
-
Goyenechea, B.1
Klix, N.2
Yelamos, J.3
Williams, G.T.4
Riddell, A.5
Neuberger, M.S.6
Milstein, C.7
-
26
-
-
34248585765
-
Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns
-
Hauser A.E., Junt T., Mempel T.R., Sneddon M.W., Kleinstein S.H., Henrickson S.E., von Andrian U.H., Shlomchik M.J., Haberman A.M. Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns. Immunity 2007, 26:655-667.
-
(2007)
Immunity
, vol.26
, pp. 655-667
-
-
Hauser, A.E.1
Junt, T.2
Mempel, T.R.3
Sneddon, M.W.4
Kleinstein, S.H.5
Henrickson, S.E.6
von Andrian, U.H.7
Shlomchik, M.J.8
Haberman, A.M.9
-
27
-
-
0242495542
-
EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching
-
He B., Raab-Traub N., Casali P., Cerutti A. EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching. J. Immunol. 2003, 171:5215-5224.
-
(2003)
J. Immunol.
, vol.171
, pp. 5215-5224
-
-
He, B.1
Raab-Traub, N.2
Casali, P.3
Cerutti, A.4
-
28
-
-
42949103482
-
Improved methods for detecting selection by mutation analysis of Ig V region sequences
-
Hershberg U., Uduman M., Shlomchik M.J., Kleinstein S.H. Improved methods for detecting selection by mutation analysis of Ig V region sequences. Int. Immunol. 2008, 20:683-694.
-
(2008)
Int. Immunol.
, vol.20
, pp. 683-694
-
-
Hershberg, U.1
Uduman, M.2
Shlomchik, M.J.3
Kleinstein, S.H.4
-
29
-
-
1242341972
-
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
-
Ito S., Nagaoka H., Shinkura R., Begum N., Muramatsu M., Nakata M., Honjo T. Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:1975-1980.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 1975-1980
-
-
Ito, S.1
Nagaoka, H.2
Shinkura, R.3
Begum, N.4
Muramatsu, M.5
Nakata, M.6
Honjo, T.7
-
30
-
-
0026060620
-
Intraclonal generation of antibody mutants in germinal centres
-
Jacob J., Kelsoe G., Rajewsky K., Weiss U. Intraclonal generation of antibody mutants in germinal centres. Nature 1991, 354:389-392.
-
(1991)
Nature
, vol.354
, pp. 389-392
-
-
Jacob, J.1
Kelsoe, G.2
Rajewsky, K.3
Weiss, U.4
-
31
-
-
33746835444
-
AUG sequences are required to sustain nonsense-codon-mediated suppression of splicing
-
Kamhi E., Yahalom G., Kass G., Hacham Y., Sperling R., Sperling J. AUG sequences are required to sustain nonsense-codon-mediated suppression of splicing. Nucleic Acids Res. 2006, 34:3421-3433.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 3421-3433
-
-
Kamhi, E.1
Yahalom, G.2
Kass, G.3
Hacham, Y.4
Sperling, R.5
Sperling, J.6
-
32
-
-
0027420437
-
Human IgM+IgD+B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life
-
Klein U., Kuppers R., Rajewsky K. Human IgM+IgD+B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life. Eur. J. Immunol. 1993, 23:3272-3277.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 3272-3277
-
-
Klein, U.1
Kuppers, R.2
Rajewsky, K.3
-
33
-
-
0142149019
-
Estimating hypermutation rates from clonal tree data
-
Kleinstein S.H., Louzoun Y., Shlomchik M.J. Estimating hypermutation rates from clonal tree data. J. Immunol. 2003, 171:4639-4649.
-
(2003)
J. Immunol.
, vol.171
, pp. 4639-4649
-
-
Kleinstein, S.H.1
Louzoun, Y.2
Shlomchik, M.J.3
-
34
-
-
0038350799
-
Why are there so few key mutant clones? The influence of stochastic selection and blocking on affinity maturation in the germinal center
-
Kleinstein S.H., Singh J.P. Why are there so few key mutant clones? The influence of stochastic selection and blocking on affinity maturation in the germinal center. Int. Immunol. 2003, 15:871-884.
-
(2003)
Int. Immunol.
, vol.15
, pp. 871-884
-
-
Kleinstein, S.H.1
Singh, J.P.2
-
35
-
-
0023161504
-
Peculiarities of immunoglobulin gene structures as a basis for somatic mutation emergence
-
Kolchanov N.A., Solovyov V.V., Rogozin I.B. Peculiarities of immunoglobulin gene structures as a basis for somatic mutation emergence. FEBS Lett. 1987, 214:87-91.
-
(1987)
FEBS Lett.
, vol.214
, pp. 87-91
-
-
Kolchanov, N.A.1
Solovyov, V.V.2
Rogozin, I.B.3
-
36
-
-
33644938791
-
Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells
-
Komori A., Xu Z., Wu X., Zan H., Casali P. Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells. Mol. Immunol. 2006, 43:1817-1826.
-
(2006)
Mol. Immunol.
, vol.43
, pp. 1817-1826
-
-
Komori, A.1
Xu, Z.2
Wu, X.3
Zan, H.4
Casali, P.5
-
37
-
-
0023722177
-
Mutational hot spots in Ig V region genes of human follicular lymphomas
-
Levy S., Mendel E., Kon S., Avnur Z., Levy R. Mutational hot spots in Ig V region genes of human follicular lymphomas. J. Exp. Med. 1988, 168:475-489.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 475-489
-
-
Levy, S.1
Mendel, E.2
Kon, S.3
Avnur, Z.4
Levy, R.5
-
38
-
-
39149099085
-
Two levels of protection for the B cell genome during somatic hypermutation
-
Liu M., Duke J.L., Richter D.J., Vinuesa C.G., Goodnow C.C., Kleinstein S.H., Schatz D.G. Two levels of protection for the B cell genome during somatic hypermutation. Nature 2008, 451:841-845.
-
(2008)
Nature
, vol.451
, pp. 841-845
-
-
Liu, M.1
Duke, J.L.2
Richter, D.J.3
Vinuesa, C.G.4
Goodnow, C.C.5
Kleinstein, S.H.6
Schatz, D.G.7
-
39
-
-
49049099076
-
Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase
-
Longo N.S., Satorius C.L., Plebani A., Durandy A., Lipsky P.E. Characterization of Ig gene somatic hypermutation in the absence of activation-induced cytidine deaminase. J. Immunol. 2008, 181:1299-1306.
-
(2008)
J. Immunol.
, vol.181
, pp. 1299-1306
-
-
Longo, N.S.1
Satorius, C.L.2
Plebani, A.3
Durandy, A.4
Lipsky, P.E.5
-
40
-
-
0028147091
-
Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing
-
Lozano F., Maertzdorf B., Pannell R., Milstein C. Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing. EMBO J. 1994, 13:4617-4622.
-
(1994)
EMBO J.
, vol.13
, pp. 4617-4622
-
-
Lozano, F.1
Maertzdorf, B.2
Pannell, R.3
Milstein, C.4
-
41
-
-
0004136246
-
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
Maniatis T., Fritch E.F., Sambrook J. Molecular Cloning: A Laboratory Manual 1989, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Maniatis, T.1
Fritch, E.F.2
Sambrook, J.3
-
42
-
-
0024458158
-
Evolution of antibody structure during the immune response. The differentiative potential of a single B lymphocyte
-
Manser T. Evolution of antibody structure during the immune response. The differentiative potential of a single B lymphocyte. J. Exp. Med. 1989, 170:1211-1230.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 1211-1230
-
-
Manser, T.1
-
43
-
-
0037126038
-
Somatic hypermutation of the AID transgene in B and non-B cells
-
Martin A., Scharff M.D. Somatic hypermutation of the AID transgene in B and non-B cells. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:12304-12308.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 12304-12308
-
-
Martin, A.1
Scharff, M.D.2
-
44
-
-
2442474264
-
Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase
-
McBride K.M., Barreto V., Ramiro A.R., Stavropoulos P., Nussenzweig M.C. Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase. J. Exp. Med. 2004, 199:1235-1244.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1235-1244
-
-
McBride, K.M.1
Barreto, V.2
Ramiro, A.R.3
Stavropoulos, P.4
Nussenzweig, M.C.5
-
45
-
-
0041931059
-
The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription
-
Michael N., Shen H.M., Longerich S., Kim N., Longacre A., Storb U. The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription. Immunity 2003, 19:235-242.
-
(2003)
Immunity
, vol.19
, pp. 235-242
-
-
Michael, N.1
Shen, H.M.2
Longerich, S.3
Kim, N.4
Longacre, A.5
Storb, U.6
-
46
-
-
13444259474
-
Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation
-
Neuberger M.S., Di Noia J.M., Beale R.C., Williams G.T., Yang Z., Rada C. Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation. Nat. Rev. Immunol. 2005, 5:171-178.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 171-178
-
-
Neuberger, M.S.1
Di Noia, J.M.2
Beale, R.C.3
Williams, G.T.4
Yang, Z.5
Rada, C.6
-
47
-
-
0031154831
-
Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts
-
Oprea M., Perelson A.S. Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts. J. Immunol. 1997, 158:5155-5162.
-
(1997)
J. Immunol.
, vol.158
, pp. 5155-5162
-
-
Oprea, M.1
Perelson, A.S.2
-
48
-
-
33747869927
-
AID mutates a non-immunoglobulin transgene independent of chromosomal position
-
Parsa J.Y., Basit W., Wang C.L., Gommerman J.L., Carlyle J.R., Martin A. AID mutates a non-immunoglobulin transgene independent of chromosomal position. Mol. Immunol. 2007, 44:567-575.
-
(2007)
Mol. Immunol.
, vol.44
, pp. 567-575
-
-
Parsa, J.Y.1
Basit, W.2
Wang, C.L.3
Gommerman, J.L.4
Carlyle, J.R.5
Martin, A.6
-
49
-
-
0028227203
-
Analysis of somatic mutation in five B cell subsets of human tonsil
-
Pascual V., Liu Y.J., Magalski A., de Bouteiller O., Banchereau J., Capra J.D. Analysis of somatic mutation in five B cell subsets of human tonsil. J. Exp. Med. 1994, 180:329-339.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 329-339
-
-
Pascual, V.1
Liu, Y.J.2
Magalski, A.3
de Bouteiller, O.4
Banchereau, J.5
Capra, J.D.6
-
50
-
-
13144259651
-
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci
-
Pasqualucci L., Migliazza A., Fracchiolla N., William C., Neri A., Baldini L., Chaganti R.S., Klein U., Kuppers R., Rajewsky K., Dalla-Favera R. BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:11816-11821.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 11816-11821
-
-
Pasqualucci, L.1
Migliazza, A.2
Fracchiolla, N.3
William, C.4
Neri, A.5
Baldini, L.6
Chaganti, R.S.7
Klein, U.8
Kuppers, R.9
Rajewsky, K.10
Dalla-Favera, R.11
-
51
-
-
42649124572
-
The biochemistry of somatic hypermutation
-
Peled J.U., Kuang F.L., Iglesias-Ussel M.D., Roa S., Kalis S.L., Goodman M.F., Scharff M.D. The biochemistry of somatic hypermutation. Annu. Rev. Immunol. 2008, 26:481-511.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 481-511
-
-
Peled, J.U.1
Kuang, F.L.2
Iglesias-Ussel, M.D.3
Roa, S.4
Kalis, S.L.5
Goodman, M.F.6
Scharff, M.D.7
-
52
-
-
34247595465
-
DNA deaminases AID and APOBEC3G act processively on single-stranded DNA
-
(author reply 693-694)
-
Pham P., Chelico L., Goodman M.F. DNA deaminases AID and APOBEC3G act processively on single-stranded DNA. DNA Repair (Amst.) 2007, 6:689-692. (author reply 693-694).
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 689-692
-
-
Pham, P.1
Chelico, L.2
Goodman, M.F.3
-
53
-
-
1542619234
-
Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process
-
Rogozin I.B., Diaz M. Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process. J. Immunol. 2004, 172:3382-3384.
-
(2004)
J. Immunol.
, vol.172
, pp. 3382-3384
-
-
Rogozin, I.B.1
Diaz, M.2
-
54
-
-
0032435650
-
TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line
-
Sale J.E., Neuberger M.S. TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line. Immunity 1998, 9:859-869.
-
(1998)
Immunity
, vol.9
, pp. 859-869
-
-
Sale, J.E.1
Neuberger, M.S.2
-
55
-
-
33847206141
-
In vivo imaging of germinal centres reveals a dynamic open structure
-
Schwickert T.A., Lindquist R.L., Shakhar G., Livshits G., Skokos D., Kosco-Vilbois M.H., Dustin M.L., Nussenzweig M.C. In vivo imaging of germinal centres reveals a dynamic open structure. Nature 2007, 446:83-87.
-
(2007)
Nature
, vol.446
, pp. 83-87
-
-
Schwickert, T.A.1
Lindquist, R.L.2
Shakhar, G.3
Livshits, G.4
Skokos, D.5
Kosco-Vilbois, M.H.6
Dustin, M.L.7
Nussenzweig, M.C.8
-
56
-
-
0033120054
-
Reconciling repertoire shift with affinity maturation: the role of deleterious mutations
-
Shannon M., Mehr R. Reconciling repertoire shift with affinity maturation: the role of deleterious mutations. J. Immunol. 1999, 162:3950-3956.
-
(1999)
J. Immunol.
, vol.162
, pp. 3950-3956
-
-
Shannon, M.1
Mehr, R.2
-
57
-
-
0033168638
-
Predicting regional mutability in antibody V genes based solely on di- and trinucleotide sequence composition
-
Shapiro G.S., Aviszus K., Ikle D., Wysocki L.J. Predicting regional mutability in antibody V genes based solely on di- and trinucleotide sequence composition. J. Immunol. 1999, 163:259-268.
-
(1999)
J. Immunol.
, vol.163
, pp. 259-268
-
-
Shapiro, G.S.1
Aviszus, K.2
Ikle, D.3
Wysocki, L.J.4
-
58
-
-
4444239054
-
Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled
-
Shen H.M., Storb U. Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:12997-13002.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 12997-13002
-
-
Shen, H.M.1
Storb, U.2
-
59
-
-
0027468552
-
Somatic hypermutation of an immunoglobulin mu heavy chain transgene
-
Sohn J., Gerstein R.M., Hsieh C.L., Lemer M., Selsing E. Somatic hypermutation of an immunoglobulin mu heavy chain transgene. J. Exp. Med. 1993, 177:493-504.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 493-504
-
-
Sohn, J.1
Gerstein, R.M.2
Hsieh, C.L.3
Lemer, M.4
Selsing, E.5
-
60
-
-
0020078033
-
Human monoclonal autoimmune antibody produced in vitro: rheumatoid factor generated by Epstein-Barr virus-transformed cell line
-
Steinitz M., Tamir S. Human monoclonal autoimmune antibody produced in vitro: rheumatoid factor generated by Epstein-Barr virus-transformed cell line. Eur. J. Immunol. 1982, 12:126-133.
-
(1982)
Eur. J. Immunol.
, vol.12
, pp. 126-133
-
-
Steinitz, M.1
Tamir, S.2
-
61
-
-
73349090583
-
Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen
-
Sutton L.A., Kostareli E., Hadzidimitriou A., Darzentas N., Tsaftaris A., Anagnostopoulos A., Rosenquist R., Stamatopoulos K. Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen. Blood 2009, 114:4460-4468.
-
(2009)
Blood
, vol.114
, pp. 4460-4468
-
-
Sutton, L.A.1
Kostareli, E.2
Hadzidimitriou, A.3
Darzentas, N.4
Tsaftaris, A.5
Anagnostopoulos, A.6
Rosenquist, R.7
Stamatopoulos, K.8
-
62
-
-
77149138374
-
Attracting AID to targets of somatic hypermutation
-
Tanaka A., Shen H.M., Ratnam S., Kodgire P., Storb U. Attracting AID to targets of somatic hypermutation. J. Exp. Med. 2010, 207:405-415.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 405-415
-
-
Tanaka, A.1
Shen, H.M.2
Ratnam, S.3
Kodgire, P.4
Storb, U.5
-
63
-
-
71849109610
-
Induction of a:T mutations is dependent on cellular environment but independent of mutation frequency and target gene location
-
Ukai A., Ishimaru K., Ouchida R., Mori H., Kano C., Moritan T., Wang J.Y. Induction of a:T mutations is dependent on cellular environment but independent of mutation frequency and target gene location. J. Immunol. 2008, 181:7835-7842.
-
(2008)
J. Immunol.
, vol.181
, pp. 7835-7842
-
-
Ukai, A.1
Ishimaru, K.2
Ouchida, R.3
Mori, H.4
Kano, C.5
Moritan, T.6
Wang, J.Y.7
-
64
-
-
0345975560
-
Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line
-
Wabl M., Burrows P.D., von Gabain A., Steinberg C. Hypermutation at the immunoglobulin heavy chain locus in a pre-B-cell line. Proc. Natl. Acad. Sci. U.S.A. 1985, 82:479-482.
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 479-482
-
-
Wabl, M.1
Burrows, P.D.2
von Gabain, A.3
Steinberg, C.4
-
66
-
-
46749122571
-
I. VH gene transcription creates stabilized secondary structures for coordinated mutagenesis during somatic hypermutation
-
Wright B.E., Schmidt K.H., Minnick M.F., Davis N. I. VH gene transcription creates stabilized secondary structures for coordinated mutagenesis during somatic hypermutation. Mol. Immunol. 2008, 45:3589-3599.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 3589-3599
-
-
Wright, B.E.1
Schmidt, K.H.2
Minnick, M.F.3
Davis, N.4
-
67
-
-
33846900907
-
Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias
-
Xiao Z., Ray M., Jiang C., Clark A.B., Rogozin I.B., Diaz M. Known components of the immunoglobulin A:T mutational machinery are intact in Burkitt lymphoma cell lines with G:C bias. Mol. Immunol. 2007, 44:2659-2666.
-
(2007)
Mol. Immunol.
, vol.44
, pp. 2659-2666
-
-
Xiao, Z.1
Ray, M.2
Jiang, C.3
Clark, A.B.4
Rogozin, I.B.5
Diaz, M.6
-
68
-
-
34249810672
-
Targeting of AID-mediated sequence diversification by cis-acting determinants
-
Yang S.Y., Schatz D.G. Targeting of AID-mediated sequence diversification by cis-acting determinants. Adv. Immunol. 2007, 94:109-125.
-
(2007)
Adv. Immunol.
, vol.94
, pp. 109-125
-
-
Yang, S.Y.1
Schatz, D.G.2
-
69
-
-
0037076967
-
AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts
-
Yoshikawa K., Okazaki I.M., Eto T., Kinoshita K., Muramatsu M., Nagaoka H., Honjo T. AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts. Science 2002, 296:2033-2036.
-
(2002)
Science
, vol.296
, pp. 2033-2036
-
-
Yoshikawa, K.1
Okazaki, I.M.2
Eto, T.3
Kinoshita, K.4
Muramatsu, M.5
Nagaoka, H.6
Honjo, T.7
-
70
-
-
0033559138
-
Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+IgD+B cell line in vitro: definition of the requirements and modalities of hypermutation
-
Zan H., Cerutti A., Dramitinos P., Schaffer A., Li Z., Casali P. Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+IgD+B cell line in vitro: definition of the requirements and modalities of hypermutation. J. Immunol. 1999, 162:3437-3447.
-
(1999)
J. Immunol.
, vol.162
, pp. 3437-3447
-
-
Zan, H.1
Cerutti, A.2
Dramitinos, P.3
Schaffer, A.4
Li, Z.5
Casali, P.6
-
71
-
-
0034813325
-
Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line
-
Zhang W., Bardwell P.D., Woo C.J., Poltoratsky V., Scharff M.D., Martin A. Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line. Int. Immunol. 2001, 13:1175-1184.
-
(2001)
Int. Immunol.
, vol.13
, pp. 1175-1184
-
-
Zhang, W.1
Bardwell, P.D.2
Woo, C.J.3
Poltoratsky, V.4
Scharff, M.D.5
Martin, A.6
-
72
-
-
0141541805
-
Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution
-
Zhao Z., Fu Y.X., Hewett-Emmett D., Boerwinkle E. Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution. Gene 2003, 312:207-213.
-
(2003)
Gene
, vol.312
, pp. 207-213
-
-
Zhao, Z.1
Fu, Y.X.2
Hewett-Emmett, D.3
Boerwinkle, E.4
-
73
-
-
15844408823
-
Differential V region mutation of two transfected Ig genes and their interaction in cultured B cell lines
-
Zhu M., Green N.S., Rabinowitz J.L., Scharff M.D. Differential V region mutation of two transfected Ig genes and their interaction in cultured B cell lines. EMBO J. 1996, 15:2738-2747.
-
(1996)
EMBO J.
, vol.15
, pp. 2738-2747
-
-
Zhu, M.1
Green, N.S.2
Rabinowitz, J.L.3
Scharff, M.D.4
|