Local microbleeding facilitates IL-6-and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells

Journal of Experimental Medicine

Volumn 208, Issue 1, 2011, Pages 103-114

  Murakami, Masaaki ^a   Okuyama, Yuko ^a   Ogura, Hideki ^a   Asano, Shogo ^a   Arima, Yasunobu ^a   Tsuruoka, Mineko ^a   Harada, Masaya ^a   Kanamoto, Minoru ^a   Sawa, Yukihisa ^a   Iwakura, Yoichiro ^c   Takatsu, Kiyoshi ^d,e   Kamimura, Daisuke ^a   Hirano, Toshio ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOYAMA   (Japan)

^e Toyama Prefectural Institute for Pharmaceutical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; INTERLEUKIN 17; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; BLEEDING; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; IN VITRO STUDY; JOINT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL; TISSUE SPECIFICITY;

ANIMALS; ANTIGENS; ARTHRITIS; HEMORRHAGE; INTERLEUKIN-17; INTERLEUKIN-6; LYMPHOCYTE ACTIVATION; MICE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TH17 CELLS;

EID: 78651474359     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20100900     Document Type: Article

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