Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: A sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation

Free Radical Biology and Medicine

Volumn 23, Issue 6, 1997, Pages 909-916

  Hazen, Stanley L ^a   Crowley, Jan R ^a   Mueller, Dianne M ^a   Heinecke, Jay W ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Box 8046   (United States)

Author keywords

3 Chlorotyrosine; Atherosclero sis; Halogenation; Inflammation; Mass spectrometry; Myeloperoxidase; Oxidation; Phagocyte

Indexed keywords

3 CHLOROTYROSINE; MYELOPEROXIDASE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

AORTA; ARTICLE; ATHEROSCLEROSIS; CATALYSIS; CHLORINATION; GAS CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; INFLAMMATION; MASS SPECTROMETRY; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; AORTA; ARTERIOSCLEROSIS; BIOLOGICAL MARKERS; CALIBRATION; CARBON; CARBON ISOTOPES; CATALYSIS; CHLORINE; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYPOCHLOROUS ACID; INFLAMMATION; LIPOPROTEINS, LDL; MALE; PEROXIDASE; SENSITIVITY AND SPECIFICITY; TYROSINE;

EID: 0030803161     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00084-1     Document Type: Article

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