Phosphoryl moieties of lipid a from Neisseria meningitidis and N. gonorrhoeae lipooligosaccharides play an important role in activation of both MyD88-and TRIF-dependent TLR4-MD-2 signaling pathways

Journal of Immunology

Volumn 185, Issue 11, 2010, Pages 6974-6984

  Liu, Mingfeng ^a,b   John, Constance M ^a   Jarvis, Gary A ^a,b  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOOLIGOSACCHARIDE; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHORYL LIPID A; PROTEIN MD 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL STRAIN; CELL SURFACE; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MONOCYTE; NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANTIGENS, CD80; CELL LINE; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON REGULATORY FACTOR-3; LIPID A; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MONOCYTES; MYELOID DIFFERENTIATION FACTOR 88; NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS; NF-KAPPA B; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 78650669108     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000953     Document Type: Article

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