The role of MyD88-like adapters in Toll-like receptor signal transduction

Biochemical Society Transactions

Volumn 31, Issue 3, 2003, Pages 643-647

  O'Neill, L A J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Host defence; Mal; Signal transduction; TIRAP; Trif

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN MYD88; B7 ANTIGEN; CD86 ANTIGEN; CELL ADHESION MOLECULE; CYTOKINE; CYTOKINE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 6; LIPOPEPTIDE; MYD88 ADAPTER LIKE PROTEIN; TIR DOMAIN CONTAINING ADAPTER INDUCING INTERFERON BETA; TIR DOMAIN CONTAINING ADAPTER PROTEIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

CONFERENCE PAPER; GENE EXPRESSION; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CELL ADHESION MOLECULES; INTERLEUKINS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 0038540887     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0310643     Document Type: Conference Paper

References (17)

1. Akira, S., Takeda, K. and Kaisho, T. (2001) Nat. Immunol. 2, 675-680
2. Medzhitov, R. (2001) Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1, 135-145
3. Janssens, S. and Beyaert, R. (2002) Trends Biochem. Sci. 27, 474-482
4. Fitzgerald, K.A., Palsson McDermott, E.M., Bowie, A.G., Jefferies, C.A., Mansell, A.S., Brady, G., Brint, E., Dunne, A., Gray, P. et al. (2001) Nature (London) 413, 78-83
5. Horng, T., Barton, G.M. and Medzhitov, R. (2001) Nat. Immunol. 2, 835-841
6. Yamamoto, M., Sato, S., Mori, K., Hoshino, K., Takeuchi, O., Takeda, K. and Akira, S. (2002) J. Immunol. 169, 6668-6672
7. Dunne, A. and O'Neill, L.A.J. (2003) Sci. STKE 171, re3
8. Suzuki, N., Suzuki, S., Duncan, G., Millar, D.G., Wada, T., Mirtsos, C., Takada, H., Wakeham, A., Itie, A., Li, S. et al. (2002) Nature (London) 416, 750-756
9. Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J.-I., Cao, Z. and Matsumoto, K. (1999) Nature (London) 398, 252-256
10. Yamamoto, M., Sato, S., Hemmi, H., Sanjo, H., Uematsu, S., Kaisho, T., Hoshino, K., Takeuchi, O., Kobayashi, M., Fujita, T. et al (2002) Nature (London) 420, 324-329
11. Horng, T., Barton, G.M., Flavell, R.A. and Medzhitov, R. (2002) Nature (London) 420, 329-333
12. Kawai, T., Adachi, O., Ogawa, T., Takeda, K. and Akira, S. (1999) Immunity 11, 115-122
13. Kawai, T., Takeuchi, O., Fujita, T., Inoue, J., Muhlradt, P.F., Sato, S., Hoshino, K. and Akira, S. (2001) J. Immunol. 167, 5887-5894
14. Doyle, S., Vaidya, S., O'Connell, R., Dadgostar, H., Dempsey, P., Wu, T., Rao, G., Sun, R., Haberland, M., Modlin, R. and Cheng, G. (2002) Immunity 17, 251-260
15. Toshchakov, V., Jones, B.W., Perera, P.Y., Thomas, K., Cody, M.J., Zhang, S., Williams, B.R., Major, J., Hamilton, T.A., Fenton, M.J. and Vogel, S. (2002) Nat. Immunol. 3, 392-398
16. Ozinsky, A., Underhill, D.M., Fontenot, J.D., Hajjar, A.M., Smith, K.D., Wilson, C.B., Schroeder, L. and Aderam, A. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 13766-13771
17. O'Neill, L.A.J., Dunne, A., Edjeback, M., Gray, P., Jefferies, C. and Wietek, C. (2003) J. Endotoxin Res. 9, 55-59