-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, et al.: Cancer statistics, 2009. CA Cancer J Clin 2009; 59: 225-249.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
67650584040
-
-
Bethesda, MD: National Cancer Institute.
-
Horner MJ, Ries LAG, Krapcho M, et al.: SEER cancer statistics review, 1975-2006. Bethesda, MD: National Cancer Institute;; 2009.
-
(2009)
SEER Cancer Statistics Review, 1975-2006
-
-
Horner, M.J.1
Ries, L.A.G.2
Krapcho, M.3
-
4
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, et al.: Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
-
5
-
-
0242720727
-
Expression profiling of epithelial plasticity in tumor progression
-
Jechlinger M, Grunert S, Tamir IH, et al.: Expression profiling of epithelial plasticity in tumor progression. Oncogene 2003; 22: 7155-7169.
-
(2003)
Oncogene
, vol.22
, pp. 7155-7169
-
-
Jechlinger, M.1
Grunert, S.2
Tamir, I.H.3
-
6
-
-
33748116186
-
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
-
Spaderna S, Schmalhofer O, Hlubek F, et al.: A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. Gastroenterology 2006; 131: 830-840.
-
(2006)
Gastroenterology
, vol.131
, pp. 830-840
-
-
Spaderna, S.1
Schmalhofer, O.2
Hlubek, F.3
-
7
-
-
21044453012
-
Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer
-
Schimanski CC, Schmitz G, Kashyap A, et al.: Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer. Oncogene 2005; 24: 3100-3109.
-
(2005)
Oncogene
, vol.24
, pp. 3100-3109
-
-
Schimanski, C.C.1
Schmitz, G.2
Kashyap, A.3
-
8
-
-
39049160267
-
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
-
Spaderna S, Schmalhofer O, Wahlbuhl M, et al.: The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res 2008; 68: 537-544.
-
(2008)
Cancer Res
, vol.68
, pp. 537-544
-
-
Spaderna, S.1
Schmalhofer, O.2
Wahlbuhl, M.3
-
9
-
-
33745086313
-
Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
-
Shioiri M, Shida T, Koda K, et al.: Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients. Br J Cancer 2006; 94: 1816-1822.
-
(2006)
Br J Cancer
, vol.94
, pp. 1816-1822
-
-
Shioiri, M.1
Shida, T.2
Koda, K.3
-
10
-
-
0035892362
-
Laminin-5 in the progression of carcinomas
-
Lohi J,: Laminin-5 in the progression of carcinomas. Int J Cancer J Int Cancer 2001; 94: 763-767.
-
(2001)
Int J Cancer J Int Cancer
, vol.94
, pp. 763-767
-
-
Lohi, J.1
-
12
-
-
0034568845
-
Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment
-
Sordat I, Rousselle P, Chaubert P, et al.: Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment. Int J Cancer J Int Cancer 2000; 88: 708-717.
-
(2000)
Int J Cancer J Int Cancer
, vol.88
, pp. 708-717
-
-
Sordat, I.1
Rousselle, P.2
Chaubert, P.3
-
13
-
-
33644912882
-
Laminin-5 (laminin-332): Unique biological activity and role in tumor growth and invasion
-
Miyazaki K,: Laminin-5 (laminin-332): Unique biological activity and role in tumor growth and invasion. Cancer Sci 2006; 97: 91-98.
-
(2006)
Cancer Sci
, vol.97
, pp. 91-98
-
-
Miyazaki, K.1
-
14
-
-
77951947152
-
The engagement of selectins and their ligands in colorectal cancer liver metastases
-
Paschos KA, Canovas D, Bird NC,: The engagement of selectins and their ligands in colorectal cancer liver metastases. J Cell Mol Med 2010; 14: 165-174.
-
(2010)
J Cell Mol Med
, vol.14
, pp. 165-174
-
-
Paschos, K.A.1
Canovas, D.2
Bird, N.C.3
-
15
-
-
60849107267
-
The role of cell adhesion molecules in the progression of colorectal cancer and the development of liver metastasis
-
Paschos KA, Canovas D, Bird NC,: The role of cell adhesion molecules in the progression of colorectal cancer and the development of liver metastasis. Cell Signal 2009; 21: 665-674.
-
(2009)
Cell Signal
, vol.21
, pp. 665-674
-
-
Paschos, K.A.1
Canovas, D.2
Bird, N.C.3
-
16
-
-
23144442645
-
Regulation of cadherin-mediated adhesion in morphogenesis
-
Gumbiner BM,: Regulation of cadherin-mediated adhesion in morphogenesis. Nat Rev Mol Cell Biol 2005; 6: 622-634.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 622-634
-
-
Gumbiner, B.M.1
-
17
-
-
0028923175
-
Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome
-
Dorudi S, Hanby AM, Poulsom R, et al.: Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome. Br J Cancer 1995; 71: 614-616.
-
(1995)
Br J Cancer
, vol.71
, pp. 614-616
-
-
Dorudi, S.1
Hanby, A.M.2
Poulsom, R.3
-
18
-
-
25444447939
-
Expression of E-cadherin, beta-catenin, and CD-44v6 cell adhesion molecules in primary tumors and metastases of colorectal adenocarcinoma
-
Delektorskaya VV, Perevoshchikov AG, Golovkov DA, et al.: Expression of E-cadherin, beta-catenin, and CD-44v6 cell adhesion molecules in primary tumors and metastases of colorectal adenocarcinoma. Bull Exp Biol Med 2005; 139: 706-710.
-
(2005)
Bull Exp Biol Med
, vol.139
, pp. 706-710
-
-
Delektorskaya, V.V.1
Perevoshchikov, A.G.2
Golovkov, D.A.3
-
19
-
-
33750438082
-
Prognostic significance of beta-catenin in colorectal cancer with liver metastasis
-
Han SA, Chun H, Park CM, et al.: Prognostic significance of beta-catenin in colorectal cancer with liver metastasis. Clin Oncol (R Coll Radiol) 2006; 18: 761-767.
-
(2006)
Clin Oncol (R Coll Radiol)
, vol.18
, pp. 761-767
-
-
Han, S.A.1
Chun, H.2
Park, C.M.3
-
20
-
-
45949094481
-
Nuclear beta-catenin expression at the invasive front and in the vessels predicts liver metastasis in colorectal carcinoma
-
Suzuki H, Masuda N, Shimura T, et al.: Nuclear beta-catenin expression at the invasive front and in the vessels predicts liver metastasis in colorectal carcinoma. Anticancer Res 2008; 28: 1821-1830.
-
(2008)
Anticancer Res
, vol.28
, pp. 1821-1830
-
-
Suzuki, H.1
Masuda, N.2
Shimura, T.3
-
21
-
-
38849201199
-
Expression of the cell-cell adhesion molecule beta-catenin in colorectal carcinomas and their metastases
-
Buhmeida A, Elzagheid A, Algars A, et al.: Expression of the cell-cell adhesion molecule beta-catenin in colorectal carcinomas and their metastases. Acta Pathol Microbiol Immunol Scand 2008; 116: 1-9.
-
(2008)
Acta Pathol Microbiol Immunol Scand
, vol.116
, pp. 1-9
-
-
Buhmeida, A.1
Elzagheid, A.2
Algars, A.3
-
22
-
-
61449495071
-
Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/beta-catenin complex
-
Choi HN, Kim KR, Lee JH, et al.: Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/beta-catenin complex. Oncol Rep 2009; 21: 57-63.
-
(2009)
Oncol Rep
, vol.21
, pp. 57-63
-
-
Choi, H.N.1
Kim, K.R.2
Lee, J.H.3
-
24
-
-
39749184140
-
Integrins: A method of early intervention in the treatment of colorectal liver metastases
-
Robertson JH, Iga AM, Sales KM, et al.: Integrins: A method of early intervention in the treatment of colorectal liver metastases. Curr Pharm Des 2008; 14: 296-305.
-
(2008)
Curr Pharm des
, vol.14
, pp. 296-305
-
-
Robertson, J.H.1
Iga, A.M.2
Sales, K.M.3
-
25
-
-
0025979573
-
Expression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases
-
Koretz K, Schlag P, Boumsell L, et al.: Expression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases. Am J Pathol 1991; 138: 741-750.
-
(1991)
Am J Pathol
, vol.138
, pp. 741-750
-
-
Koretz, K.1
Schlag, P.2
Boumsell, L.3
-
26
-
-
0031017019
-
Role of alpha 5 beta 1 integrin in determining malignant properties of colon carcinoma cells
-
Gong J, Wang D, Sun L, et al.: Role of alpha 5 beta 1 integrin in determining malignant properties of colon carcinoma cells. Cell Growth Differ Mol Biol J Am Assoc Cancer Res 1997; 8: 83-90.
-
(1997)
Cell Growth Differ Mol Biol J Am Assoc Cancer Res
, vol.8
, pp. 83-90
-
-
Gong, J.1
Wang, D.2
Sun, L.3
-
27
-
-
39549097542
-
Blocking alpha2 integrins on rat CC531s colon carcinoma cells prevents operation-induced augmentation of liver metastases outgrowth
-
Van Der Bij G, Oosterling S, Bögels M, et al.: Blocking alpha2 integrins on rat CC531s colon carcinoma cells prevents operation-induced augmentation of liver metastases outgrowth. Hepatology 2008; 47: 532-543.
-
(2008)
Hepatology
, vol.47
, pp. 532-543
-
-
Van Der Bij, G.1
Oosterling, S.2
Bögels, M.3
-
28
-
-
0032793097
-
Laminin mediates tethering and spreading of colon cancer cells in physiological shear flow
-
Kitayama J, Nagawa H, Tsuno N, et al.: Laminin mediates tethering and spreading of colon cancer cells in physiological shear flow. Br J Cancer 1999; 80: 1927-1934.
-
(1999)
Br J Cancer
, vol.80
, pp. 1927-1934
-
-
Kitayama, J.1
Nagawa, H.2
Tsuno, N.3
-
29
-
-
14944348752
-
Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma
-
Bates RC, Bellovin DI, Brown C, et al.: Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma. J Clin Invest 2005; 115: 339-347.
-
(2005)
J Clin Invest
, vol.115
, pp. 339-347
-
-
Bates, R.C.1
Bellovin, D.I.2
Brown, C.3
-
30
-
-
49749092745
-
Suppression of integrin alphaupsilonbeta6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway
-
Wang J, Zhang Z, Xu K, et al.: Suppression of integrin alphaupsilonbeta6 by RNA interference in colon cancer cells inhibits extracellular matrix degradation through the MAPK pathway. Int J Cancer J Int Cancer 2008; 123: 1311-1317.
-
(2008)
Int J Cancer J Int Cancer
, vol.123
, pp. 1311-1317
-
-
Wang, J.1
Zhang, Z.2
Xu, K.3
-
31
-
-
58149187467
-
The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation
-
Conti JA, Kendall TJ, Bateman A, et al.: The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation. Clin Cancer Res Off J Am Assoc Cancer Res 2008; 14: 6405-6413.
-
(2008)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.14
, pp. 6405-6413
-
-
Conti, J.A.1
Kendall, T.J.2
Bateman, A.3
-
32
-
-
70349754433
-
Integrin α2 mediates selective metastasis to the liver
-
Yoshimura K, Meckel K, Laird L, et al.: Integrin α2 mediates selective metastasis to the liver. Cancer Res 2009; 69: 7320-7328.
-
(2009)
Cancer Res
, vol.69
, pp. 7320-7328
-
-
Yoshimura, K.1
Meckel, K.2
Laird, L.3
-
33
-
-
0028108393
-
Structural motifs for recognition and adhesion in members of the immunoglobulin superfamily
-
Holness CL, Simmons DL,: Structural motifs for recognition and adhesion in members of the immunoglobulin superfamily. J Cell Sci 1994; 107: 2065-2070.
-
(1994)
J Cell Sci
, vol.107
, pp. 2065-2070
-
-
Holness, C.L.1
Simmons, D.L.2
-
35
-
-
0033057177
-
The carcinoembryonic antigen (CEA) family: Structures, suggested functions and expression in normal and malignant tissues
-
Hammarstrom S,: The carcinoembryonic antigen (CEA) family: Structures, suggested functions and expression in normal and malignant tissues. Semin Cancer Biol 1999; 9: 67-81.
-
(1999)
Semin Cancer Biol
, vol.9
, pp. 67-81
-
-
Hammarstrom, S.1
-
36
-
-
0036118491
-
Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation
-
Ilantzis C, DeMarte L, Screaton RA, et al.: Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation. Neoplasia (New York, NY) 2002; 4: 151-163.
-
(2002)
Neoplasia (New York, NY)
, vol.4
, pp. 151-163
-
-
Ilantzis, C.1
Demarte, L.2
Screaton, R.A.3
-
37
-
-
34250353411
-
Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling
-
Samara RN, Laguinge LM, Jessup JM,: Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling. Cancer Res 2007; 67: 4774-4782.
-
(2007)
Cancer Res
, vol.67
, pp. 4774-4782
-
-
Samara, R.N.1
Laguinge, L.M.2
Jessup, J.M.3
-
38
-
-
34247522572
-
A co-clustering model involving alpha5beta1 integrin for the biological effects of GPI-anchored human carcinoembryonic antigen (CEA)
-
Camacho-Leal P, Zhai AB, Stanners CP,: A co-clustering model involving alpha5beta1 integrin for the biological effects of GPI-anchored human carcinoembryonic antigen (CEA). J Cell Physiol 2007; 211: 791-802.
-
(2007)
J Cell Physiol
, vol.211
, pp. 791-802
-
-
Camacho-Leal, P.1
Zhai, A.B.2
Stanners, C.P.3
-
39
-
-
0020322699
-
A new Kupffer cell receptor mediating plasma clearance of carcinoembryonic antigen by the rat
-
Toth CA, Thomas P, Broitman SA, et al.: A new Kupffer cell receptor mediating plasma clearance of carcinoembryonic antigen by the rat. Biochem J 1982; 204: 377-381.
-
(1982)
Biochem J
, vol.204
, pp. 377-381
-
-
Toth, C.A.1
Thomas, P.2
Broitman, S.A.3
-
40
-
-
0035866769
-
Role of carcinoembryonic antigen in the progression of colon cancer cells that express carbohydrate antigen
-
Minami S, Furui J, Kanematsu T,: Role of carcinoembryonic antigen in the progression of colon cancer cells that express carbohydrate antigen. Cancer Res 2001; 61: 2732-2735.
-
(2001)
Cancer Res
, vol.61
, pp. 2732-2735
-
-
Minami, S.1
Furui, J.2
Kanematsu, T.3
-
41
-
-
34249811532
-
Carcinoembryonic antigen-stimulated THP-1 macrophages activate endothelial cells and increase cell-cell adhesion of colorectal cancer cells
-
Aarons CB, Bajenova O, Andrews C, et al.: Carcinoembryonic antigen-stimulated THP-1 macrophages activate endothelial cells and increase cell-cell adhesion of colorectal cancer cells. Clin Exp Metastasis 2007; 24: 201-209.
-
(2007)
Clin Exp Metastasis
, vol.24
, pp. 201-209
-
-
Aarons, C.B.1
Bajenova, O.2
Andrews, C.3
-
42
-
-
63849339429
-
The high affinity selectin glycan ligand C2-O-sLex and mRNA transcripts of the core 2 beta-1,6-N-acetylglucosaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas
-
St Hill CA, Farooqui M, Mitcheltree G, et al.: The high affinity selectin glycan ligand C2-O-sLex and mRNA transcripts of the core 2 beta-1,6-N- acetylglucosaminyltransferase (C2GnT1) gene are highly expressed in human colorectal adenocarcinomas. BMC Cancer 2009; 9: 79.
-
(2009)
BMC Cancer
, vol.9
, pp. 79
-
-
St Hill, C.A.1
Farooqui, M.2
Mitcheltree, G.3
-
43
-
-
0035877986
-
Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice
-
Sperandio M, Thatte A, Foy D, et al.: Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice. Blood 2001; 97: 3812-3819.
-
(2001)
Blood
, vol.97
, pp. 3812-3819
-
-
Sperandio, M.1
Thatte, A.2
Foy, D.3
-
44
-
-
0027499085
-
Expression of CD44R1 adhesion molecule in colon carcinomas and metastases
-
Tanabe KK, Ellis LM, Saya H,: Expression of CD44R1 adhesion molecule in colon carcinomas and metastases. Lancet 1993; 341: 725.
-
(1993)
Lancet
, vol.341
, pp. 725
-
-
Tanabe, K.K.1
Ellis, L.M.2
Saya, H.3
-
45
-
-
34250792850
-
A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression
-
Kuhn S, Koch M, Nabel T, et al.: A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression. Mol Cancer Res 2007; 5: 553-567.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 553-567
-
-
Kuhn, S.1
Koch, M.2
Nabel, T.3
-
46
-
-
0030980675
-
Expression of CD44 splice variants in colorectal cancer
-
Wong LS, Cantrill JE, Morris AG, et al.: Expression of CD44 splice variants in colorectal cancer. Br J Surg 1997; 84: 363-367.
-
(1997)
Br J Surg
, vol.84
, pp. 363-367
-
-
Wong, L.S.1
Cantrill, J.E.2
Morris, A.G.3
-
47
-
-
0031776902
-
CD44V6 expression in human colorectal carcinoma
-
Coppola D, Hyacinthe M, Fu L, et al.: CD44V6 expression in human colorectal carcinoma. Hum Pathol 1998; 29: 627-635.
-
(1998)
Hum Pathol
, vol.29
, pp. 627-635
-
-
Coppola, D.1
Hyacinthe, M.2
Fu, L.3
-
48
-
-
0037693895
-
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
-
Visse R, Nagase H,: Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry. Circ Res 2003; 92: 827-839.
-
(2003)
Circ Res
, vol.92
, pp. 827-839
-
-
Visse, R.1
Nagase, H.2
-
49
-
-
1242292412
-
Role of matrix metalloproteinases (MMPs) in colorectal cancer
-
Zucker S, Vacirca J,: Role of matrix metalloproteinases (MMPs) in colorectal cancer. Cancer Metastasis Rev 2004; 23: 101-117.
-
(2004)
Cancer Metastasis Rev
, vol.23
, pp. 101-117
-
-
Zucker, S.1
Vacirca, J.2
-
50
-
-
23344454275
-
Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples
-
Pesta M, Holubec L, Topolcan O, et al.: Quantitative estimation of matrix metalloproteinases 2 and 7 (MMP-2, MMP-7) and tissue inhibitors of matrix metalloproteinases 1 and 2 (TIMP-1, TIMP-2) in colorectal carcinoma tissue samples. Anticancer Res 2005; 25: 3387-3391.
-
(2005)
Anticancer Res
, vol.25
, pp. 3387-3391
-
-
Pesta, M.1
Holubec, L.2
Topolcan, O.3
-
51
-
-
34547141354
-
Clinical, biological, and molecular aspects of metastasis in colorectal cancer
-
Stein U, Schlag PM,: Clinical, biological, and molecular aspects of metastasis in colorectal cancer. Recent Results Cancer Res 2007; 176: 61-80.
-
(2007)
Recent Results Cancer Res
, vol.176
, pp. 61-80
-
-
Stein, U.1
Schlag, P.M.2
-
52
-
-
28844498773
-
Molecular mechanisms of hepatic metastasis in colorectal cancer
-
Rudmik LR, Magliocco AM,: Molecular mechanisms of hepatic metastasis in colorectal cancer. J Surg Oncol 2005; 92: 347-359.
-
(2005)
J Surg Oncol
, vol.92
, pp. 347-359
-
-
Rudmik, L.R.1
Magliocco, A.M.2
-
53
-
-
34648829207
-
Prognostic significance of expression of matrix metalloproteinase in colorectal adenocarcinomas and their metastases
-
Delektorskaya VV, Perevoshchikov AG, Golovkov DA, et al.: Prognostic significance of expression of matrix metalloproteinase in colorectal adenocarcinomas and their metastases. Bull Exp Biol Med 2007; 143: 455-458.
-
(2007)
Bull Exp Biol Med
, vol.143
, pp. 455-458
-
-
Delektorskaya, V.V.1
Perevoshchikov, A.G.2
Golovkov, D.A.3
-
54
-
-
67650140630
-
Key enzymes of the extracellular matrix in colorectal cancer
-
Golovkov DA,: Key enzymes of the extracellular matrix in colorectal cancer. Bull Exp Biol Med 2009; 147: 353-356.
-
(2009)
Bull Exp Biol Med
, vol.147
, pp. 353-356
-
-
Golovkov, D.A.1
-
55
-
-
61449230902
-
Differences in the gene expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in primary colorectal tumors and their synchronous liver metastases
-
Gentner B, Wein A, Croner RS, et al.: Differences in the gene expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in primary colorectal tumors and their synchronous liver metastases. Anticancer Res 2009; 29: 67-74.
-
(2009)
Anticancer Res
, vol.29
, pp. 67-74
-
-
Gentner, B.1
Wein, A.2
Croner, R.S.3
-
56
-
-
41149085227
-
Prognostic values of matrix metalloproteinase family expression in human colorectal carcinoma
-
Asano T, Tada M, Cheng S, et al.: Prognostic values of matrix metalloproteinase family expression in human colorectal carcinoma. J Surg Res 2008; 146: 32-42.
-
(2008)
J Surg Res
, vol.146
, pp. 32-42
-
-
Asano, T.1
Tada, M.2
Cheng, S.3
-
57
-
-
40649121508
-
Evolving role of uPA/uPAR system in human cancers
-
Dass K, Ahmad A, Azmi AS, et al.: Evolving role of uPA/uPAR system in human cancers. Cancer Treat Rev 2008; 34: 122-136.
-
(2008)
Cancer Treat Rev
, vol.34
, pp. 122-136
-
-
Dass, K.1
Ahmad, A.2
Azmi, A.S.3
-
58
-
-
0033583761
-
Plasma urokinase receptor levels in patients with colorectal cancer: Relationship to prognosis
-
Stephens RW, Nielsen HJ, Christensen IJ, et al.: Plasma urokinase receptor levels in patients with colorectal cancer: Relationship to prognosis. J Natl Cancer Inst 1999; 91: 869-874.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 869-874
-
-
Stephens, R.W.1
Nielsen, H.J.2
Christensen, I.J.3
-
59
-
-
0032515761
-
Association between plasma concentrations of plasminogen activator inhibitor-1 and survival in patients with colorectal cancer
-
Nielsen HJ, Pappot H, Christensen IJ, et al.: Association between plasma concentrations of plasminogen activator inhibitor-1 and survival in patients with colorectal cancer. Br Med J (Clin Res Ed) 1998; 316: 829-830.
-
(1998)
Br Med J (Clin Res Ed)
, vol.316
, pp. 829-830
-
-
Nielsen, H.J.1
Pappot, H.2
Christensen, I.J.3
-
60
-
-
0029144854
-
Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas
-
Pyke C, Salo S, Ralfkiaer E, et al.: Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res 1995; 55: 4132-4139.
-
(1995)
Cancer Res
, vol.55
, pp. 4132-4139
-
-
Pyke, C.1
Salo, S.2
Ralfkiaer, E.3
-
61
-
-
0034782184
-
Liver metastases from colorectal adenocarcinomas grow in three patterns with different angiogenesis and desmoplasia
-
Vermeulen PB, Colpaert C, Salgado R, et al.: Liver metastases from colorectal adenocarcinomas grow in three patterns with different angiogenesis and desmoplasia. J Pathol 2001; 195: 336-342.
-
(2001)
J Pathol
, vol.195
, pp. 336-342
-
-
Vermeulen, P.B.1
Colpaert, C.2
Salgado, R.3
-
62
-
-
62449284577
-
Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases
-
Illemann M, Bird N, Majeed A, et al.: Two distinct expression patterns of urokinase, urokinase receptor and plasminogen activator inhibitor-1 in colon cancer liver metastases. Int J Cancer 2009; 124: 1860-1870.
-
(2009)
Int J Cancer
, vol.124
, pp. 1860-1870
-
-
Illemann, M.1
Bird, N.2
Majeed, A.3
-
63
-
-
0033810052
-
Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis
-
Friedmann Y, Vlodavsky I, Aingorn H, et al.: Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis. Am J Pathol 2000; 157: 1167-1175.
-
(2000)
Am J Pathol
, vol.157
, pp. 1167-1175
-
-
Friedmann, Y.1
Vlodavsky, I.2
Aingorn, H.3
-
64
-
-
0028946604
-
Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer
-
Di Renzo MF, Olivero M, Giacomini A, et al.: Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer. Clin Cancer Res Off J Am Assoc Cancer Res 1995; 1: 147-154.
-
(1995)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.1
, pp. 147-154
-
-
Di Renzo, M.F.1
Olivero, M.2
Giacomini, A.3
-
65
-
-
0038604793
-
Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin
-
Herynk MH, Tsan R, Radinsky R, et al.: Activation of c-Met in colorectal carcinoma cells leads to constitutive association of tyrosine-phosphorylated beta-catenin. Clin Exp Metastasis 2003; 20: 291-300.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 291-300
-
-
Herynk, M.H.1
Tsan, R.2
Radinsky, R.3
-
66
-
-
58149352266
-
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
-
Stein U, Walther W, Arlt F, et al.: MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nat Med 2009; 15: 59-67.
-
(2009)
Nat Med
, vol.15
, pp. 59-67
-
-
Stein, U.1
Walther, W.2
Arlt, F.3
-
67
-
-
77949329326
-
Chemokines and chemokine receptors: New insights into cancer-related inflammation
-
Lazennec G, Richmond A,: Chemokines and chemokine receptors: New insights into cancer-related inflammation. Trends Mol Med 2010; 16: 133-144.
-
(2010)
Trends Mol Med
, vol.16
, pp. 133-144
-
-
Lazennec, G.1
Richmond, A.2
-
68
-
-
77953288700
-
Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival
-
Doll D, Keller L, Maak M, et al.: Differential expression of the chemokines GRO-2, GRO-3, and interleukin-8 in colon cancer and their impact on metastatic disease and survival. Int J Colorectal Dis 2010; 25: 573-581.
-
(2010)
Int J Colorectal Dis
, vol.25
, pp. 573-581
-
-
Doll, D.1
Keller, L.2
Maak, M.3
-
69
-
-
34848813857
-
Correlation of IL-8 with induction, progression and metastatic potential of colorectal cancer
-
Rubie C, Frick VO, Pfeil S, et al.: Correlation of IL-8 with induction, progression and metastatic potential of colorectal cancer. World J Gastroenterol 2007; 13: 4996-5002.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 4996-5002
-
-
Rubie, C.1
Frick, V.O.2
Pfeil, S.3
-
70
-
-
60349085081
-
The chemokine receptors CXCR4 and CXCR3 in cancer
-
Fulton AM,: The chemokine receptors CXCR4 and CXCR3 in cancer. Curr Oncol Rep 2009; 11: 125-131.
-
(2009)
Curr Oncol Rep
, vol.11
, pp. 125-131
-
-
Fulton, A.M.1
-
71
-
-
0038079014
-
The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases
-
Zeelenberg IS, Ruuls-Van Stalle L, Roos E,: The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. Cancer Res 2003; 63: 3833-3839.
-
(2003)
Cancer Res
, vol.63
, pp. 3833-3839
-
-
Zeelenberg, I.S.1
Ruuls-Van Stalle, L.2
Roos, E.3
-
72
-
-
18444401114
-
Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival
-
Kim J, Takeuchi H, Lam ST, et al.: Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival. J Clin Oncol Off J Am Soc Clin Oncol 2005; 23: 2744-2753.
-
(2005)
J Clin Oncol off J Am Soc Clin Oncol
, vol.23
, pp. 2744-2753
-
-
Kim, J.1
Takeuchi, H.2
Lam, S.T.3
-
73
-
-
20144389538
-
Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer
-
Schimanski CC, Schwald S, Simiantonaki N, et al.: Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer. Clin Cancer Res Off J Am Assoc Cancer Res 2005; 11: 1743-1750.
-
(2005)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.11
, pp. 1743-1750
-
-
Schimanski, C.C.1
Schwald, S.2
Simiantonaki, N.3
-
74
-
-
68949200810
-
Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis
-
Matsusue R, Kubo H, Hisamori S, et al.: Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis. Ann Surg Oncol 2009; 16: 2645-2653.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2645-2653
-
-
Matsusue, R.1
Kubo, H.2
Hisamori, S.3
-
75
-
-
69949092197
-
Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis
-
Hu H, Sun L, Guo C, et al.: Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis. Clin Cancer Res Off J Am Assoc Cancer Res 2009; 15: 5485-5493.
-
(2009)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.15
, pp. 5485-5493
-
-
Hu, H.1
Sun, L.2
Guo, C.3
-
76
-
-
33646350054
-
Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer
-
Ghadjar P, Coupland SE, Na IK, et al.: Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer. J Clin Oncol Off J Am Soc Clin Oncol 2006; 24: 1910-1916.
-
(2006)
J Clin Oncol off J Am Soc Clin Oncol
, vol.24
, pp. 1910-1916
-
-
Ghadjar, P.1
Coupland, S.E.2
Na, I.K.3
-
78
-
-
0035834386
-
A phosphatase associated with metastasis of colorectal cancer
-
Saha S, Bardelli A, Buckhaults P, et al.: A phosphatase associated with metastasis of colorectal cancer. Science (New York, NY) 2001; 294: 1343-1346.
-
(2001)
Science (New York, NY)
, vol.294
, pp. 1343-1346
-
-
Saha, S.1
Bardelli, A.2
Buckhaults, P.3
-
79
-
-
8444228839
-
High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: A predictive molecular marker of metachronous liver and lung metastases
-
Kato H, Semba S, Miskad UA, et al.: High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: A predictive molecular marker of metachronous liver and lung metastases. Clin Cancer Res Off J Am Assoc Cancer Res 2004; 10: 7318-7328.
-
(2004)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.10
, pp. 7318-7328
-
-
Kato, H.1
Semba, S.2
Miskad, U.A.3
-
80
-
-
60349088869
-
Prognostic value of PRL-3 overexpression in early stages of colonic cancer
-
Xing X, Peng L, Qu L, et al.: Prognostic value of PRL-3 overexpression in early stages of colonic cancer. Histopathology 2009; 54: 309-318.
-
(2009)
Histopathology
, vol.54
, pp. 309-318
-
-
Xing, X.1
Peng, L.2
Qu, L.3
-
81
-
-
70349939382
-
Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer
-
Siena S, Sartore-Bianchi A, Di Nicolantonio F, et al.: Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. J Natl Cancer Instit 2009; 101: 1308-1324.
-
(2009)
J Natl Cancer Instit
, vol.101
, pp. 1308-1324
-
-
Siena, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
-
82
-
-
68149175266
-
Multiplexed cell signaling analysis of metastatic and nonmetastatic colorectal cancer reveals COX2-EGFR signaling activation as a potential prognostic pathway biomarker
-
Pierobon M, Calvert V, Belluco C, et al.: Multiplexed cell signaling analysis of metastatic and nonmetastatic colorectal cancer reveals COX2-EGFR signaling activation as a potential prognostic pathway biomarker. Clin Colorectal Cancer 2009; 8: 110-117.
-
(2009)
Clin Colorectal Cancer
, vol.8
, pp. 110-117
-
-
Pierobon, M.1
Calvert, V.2
Belluco, C.3
-
83
-
-
42249101554
-
Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer
-
Yamada M, Ichikawa Y, Yamagishi S, et al.: Amphiregulin is a promising prognostic marker for liver metastases of colorectal cancer. Clin Cancer Res Off J Am Assoc Cancer Res 2008; 14: 2351-2356.
-
(2008)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.14
, pp. 2351-2356
-
-
Yamada, M.1
Ichikawa, Y.2
Yamagishi, S.3
-
84
-
-
77953666101
-
The VEGF family in cancer and antibody-based strategies for their inhibition
-
[Epub ahead of print].
-
Sullivan LA, Brekken RA,: The VEGF family in cancer and antibody-based strategies for their inhibition. mAbs 2010; 2: 165-175. [Epub ahead of print].
-
(2010)
MAbs
, vol.2
, pp. 165-175
-
-
Sullivan, L.A.1
Brekken, R.A.2
-
85
-
-
0031866661
-
Vascular endothelial growth factor expression is reduced in liver metastasis from colorectal cancer and correlates with urokinase-type plasminogen activator
-
Berney CR, Yang JL, Fisher RJ, et al.: Vascular endothelial growth factor expression is reduced in liver metastasis from colorectal cancer and correlates with urokinase-type plasminogen activator. Anticancer Res 1998; 18: 973-977.
-
(1998)
Anticancer Res
, vol.18
, pp. 973-977
-
-
Berney, C.R.1
Yang, J.L.2
Fisher, R.J.3
-
86
-
-
0034164580
-
Expression of vascular endothelial growth factor and thrombospondin-1 in colorectal carcinoma
-
Maeda K, Nishiguchi Y, Yashiro M, et al.: Expression of vascular endothelial growth factor and thrombospondin-1 in colorectal carcinoma. Int J Mol Med 2000; 5: 373-378.
-
(2000)
Int J Mol Med
, vol.5
, pp. 373-378
-
-
Maeda, K.1
Nishiguchi, Y.2
Yashiro, M.3
-
87
-
-
31544433148
-
Vascular endothelial growth factor messenger RNA expression level is preserved in liver metastases compared with corresponding primary colorectal cancer
-
Kuramochi H, Hayashi K, Uchida K, et al.: Vascular endothelial growth factor messenger RNA expression level is preserved in liver metastases compared with corresponding primary colorectal cancer. Clin Cancer Res Off J Am Assoc Cancer Res 2006; 12: 29-33.
-
(2006)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.12
, pp. 29-33
-
-
Kuramochi, H.1
Hayashi, K.2
Uchida, K.3
-
88
-
-
67650753834
-
The role of the angiopoietins in vascular morphogenesis
-
Thomas M, Augustin H,: The role of the angiopoietins in vascular morphogenesis. Angiogenesis 2009; 12: 125-137.
-
(2009)
Angiogenesis
, vol.12
, pp. 125-137
-
-
Thomas, M.1
Augustin, H.2
-
89
-
-
0035447959
-
Differential expression of angiopoietin-1 and angiopoietin-2 in colon carcinoma. A possible mechanism for the initiation of angiogenesis
-
Ahmad SA, Liu W, Jung YD, et al.: Differential expression of angiopoietin-1 and angiopoietin-2 in colon carcinoma. A possible mechanism for the initiation of angiogenesis. Cancer 2001; 92: 1138-1143.
-
(2001)
Cancer
, vol.92
, pp. 1138-1143
-
-
Ahmad, S.A.1
Liu, W.2
Jung, Y.D.3
-
90
-
-
33845188987
-
Expression and prognostic significance of angiopoietin in colorectal carcinoma
-
Chung YC, Hou YC, Chang CN, et al.: Expression and prognostic significance of angiopoietin in colorectal carcinoma. J Surg Oncol 2006; 94: 631-638.
-
(2006)
J Surg Oncol
, vol.94
, pp. 631-638
-
-
Chung, Y.C.1
Hou, Y.C.2
Chang, C.N.3
-
92
-
-
25144508039
-
Expression of thrombospondin-1 in resected colorectal liver metastases predicts poor prognosis
-
Sutton CD, O'Byrne K, Goddard JC, et al.: Expression of thrombospondin-1 in resected colorectal liver metastases predicts poor prognosis. Clin Cancer Res Off J Am Assoc Cancer Res 2005; 11: 6567-6573.
-
(2005)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.11
, pp. 6567-6573
-
-
Sutton, C.D.1
O'Byrne, K.2
Goddard, J.C.3
-
93
-
-
0035403794
-
Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer
-
Maeda K, Nishiguchi Y, Kang SM, et al.: Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer. Oncol Rep 2001; 8: 763-766.
-
(2001)
Oncol Rep
, vol.8
, pp. 763-766
-
-
Maeda, K.1
Nishiguchi, Y.2
Kang, S.M.3
-
94
-
-
0032894743
-
Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer
-
Tokunaga T, Nakamura M, Oshika Y, et al.: Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer. Br J Cancer 1999; 79: 354-359.
-
(1999)
Br J Cancer
, vol.79
, pp. 354-359
-
-
Tokunaga, T.1
Nakamura, M.2
Oshika, Y.3
-
95
-
-
32444442819
-
Angiogenesis and p53 at the invading tumor edge: Prognostic markers for colorectal cancer beyond stage
-
Georgiou L, Minopoulos G, Lirantzopoulos N, et al.: Angiogenesis and p53 at the invading tumor edge: Prognostic markers for colorectal cancer beyond stage. J Surg Res 2006; 131: 118-123.
-
(2006)
J Surg Res
, vol.131
, pp. 118-123
-
-
Georgiou, L.1
Minopoulos, G.2
Lirantzopoulos, N.3
-
96
-
-
67650995763
-
Clinical significance of microvessel count in patients with metastatic liver cancer originating from colorectal carcinoma
-
Nanashima A, Shibata K, Nakayama T, et al.: Clinical significance of microvessel count in patients with metastatic liver cancer originating from colorectal carcinoma. Ann Surg Oncol 2009; 16: 2130-2137.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2130-2137
-
-
Nanashima, A.1
Shibata, K.2
Nakayama, T.3
-
97
-
-
67949094077
-
COX-2, VEGF and tumour angiogenesis
-
Toomey D, Murphy J, Conlon K,: COX-2, VEGF and tumour angiogenesis. Surgeon 2009; 7: 174-180.
-
(2009)
Surgeon
, vol.7
, pp. 174-180
-
-
Toomey, D.1
Murphy, J.2
Conlon, K.3
-
98
-
-
76849095665
-
The role of COX-2 in intestinal inflammation and colorectal cancer
-
Wang D, Dubois RN,: The role of COX-2 in intestinal inflammation and colorectal cancer. Oncogene 2009; 29: 781-788.
-
(2009)
Oncogene
, vol.29
, pp. 781-788
-
-
Wang, D.1
Dubois, R.N.2
-
99
-
-
11144224065
-
Cyclooxygenase-2 expression: A significant prognostic indicator for patients with colorectal cancer
-
Soumaoro LT, Uetake H, Higuchi T, et al.: Cyclooxygenase-2 expression: A significant prognostic indicator for patients with colorectal cancer. Clin Cancer Res Off J Am Assoc Cancer Res 2004; 10: 8465-8471.
-
(2004)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.10
, pp. 8465-8471
-
-
Soumaoro, L.T.1
Uetake, H.2
Higuchi, T.3
-
100
-
-
67649446846
-
Messenger RNA expression of COX-2 and angiogenic factors in primary colorectal cancer and corresponding liver metastasis
-
Kobayashi H, Sugihara K, Uetake H, et al.: Messenger RNA expression of COX-2 and angiogenic factors in primary colorectal cancer and corresponding liver metastasis. Int J Oncol 2009; 34: 1147-1153.
-
(2009)
Int J Oncol
, vol.34
, pp. 1147-1153
-
-
Kobayashi, H.1
Sugihara, K.2
Uetake, H.3
-
101
-
-
35448968987
-
Correlations between cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer
-
Nakamoto RH, Uetake H, Iida S, et al.: Correlations between cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer. Jpn J Clin Oncol 2007; 37: 679-685.
-
(2007)
Jpn J Clin Oncol
, vol.37
, pp. 679-685
-
-
Nakamoto, R.H.1
Uetake, H.2
Iida, S.3
-
102
-
-
72449176846
-
Molecular origins of cancer: Molecular basis of colorectal cancer
-
Markowitz SD, Bertagnolli MM,: Molecular origins of cancer: Molecular basis of colorectal cancer. N Engl J Med 2009; 361: 2449-2460.
-
(2009)
N Engl J Med
, vol.361
, pp. 2449-2460
-
-
Markowitz, S.D.1
Bertagnolli, M.M.2
-
103
-
-
0029125551
-
Increased incidence of p53 mutations is associated with hepatic metastasis in colorectal neoplastic progression
-
Kastrinakis W, Ramchurren N, Rieger K, et al.: Increased incidence of p53 mutations is associated with hepatic metastasis in colorectal neoplastic progression. Oncogene 1995; 11: 647-652.
-
(1995)
Oncogene
, vol.11
, pp. 647-652
-
-
Kastrinakis, W.1
Ramchurren, N.2
Rieger, K.3
-
104
-
-
17144473545
-
The status of p53 in the metastatic progression of colorectal cancer
-
Heide I, Thiede C, Sonntag T, et al.: The status of p53 in the metastatic progression of colorectal cancer. Eur J Cancer (Oxford, England: 1990) 1997; 33: 1314-1322.
-
(1997)
Eur J Cancer (Oxford, England: 1990)
, vol.33
, pp. 1314-1322
-
-
Heide, I.1
Thiede, C.2
Sonntag, T.3
-
105
-
-
0029130604
-
P53 Mutations in matched primary and metastatic human tumors
-
Peller S, Halevy A, Slutzki S, et al.: p53 Mutations in matched primary and metastatic human tumors. Mol Carcinog 1995; 13: 166-172.
-
(1995)
Mol Carcinog
, vol.13
, pp. 166-172
-
-
Peller, S.1
Halevy, A.2
Slutzki, S.3
-
106
-
-
20344370492
-
P53 mutation analysis of colorectal liver metastases: Relation to actual survival, angiogenic status, and p53 overexpression
-
de Jong KP, Gouw AS, Peeters PM, et al.: P53 mutation analysis of colorectal liver metastases: Relation to actual survival, angiogenic status, and p53 overexpression. Clin Cancer Res Off J Am Assoc Cancer Res 2005; 11: 4067-4073.
-
(2005)
Clin Cancer Res off J Am Assoc Cancer Res
, vol.11
, pp. 4067-4073
-
-
De Jong, K.P.1
Gouw, A.S.2
Peeters, P.M.3
-
107
-
-
33749256649
-
Structural, functional and therapeutic biology of survivin
-
Sah NK, Khan Z, Khan GJ, et al.: Structural, functional and therapeutic biology of survivin. Cancer Lett 2006; 244: 164-171.
-
(2006)
Cancer Lett
, vol.244
, pp. 164-171
-
-
Sah, N.K.1
Khan, Z.2
Khan, G.J.3
-
108
-
-
61349092242
-
Expression of survivin and cortactin in colorectal adenocarcinoma: Association with clinicopathological parameters
-
Lee YY, Yu CP, Lin CK, et al.: Expression of survivin and cortactin in colorectal adenocarcinoma: Association with clinicopathological parameters. Dis Markers 2009; 26: 9-18.
-
(2009)
Dis Markers
, vol.26
, pp. 9-18
-
-
Lee, Y.Y.1
Yu, C.P.2
Lin, C.K.3
-
109
-
-
67649460732
-
Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer
-
Fang Y, Lu Z, Wang G, et al.: Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer. Int J Colorectal Dis 2009; 24: 875-884.
-
(2009)
Int J Colorectal Dis
, vol.24
, pp. 875-884
-
-
Fang, Y.1
Lu, Z.2
Wang, G.3
-
110
-
-
45849134073
-
Frizzled-7 as a potential therapeutic target in colorectal cancer
-
Ueno K, Hiura M, Suehiro Y, et al.: Frizzled-7 as a potential therapeutic target in colorectal cancer. Neoplasia (New York, NY) 2008; 10: 697-705.
-
(2008)
Neoplasia (New York, NY)
, vol.10
, pp. 697-705
-
-
Ueno, K.1
Hiura, M.2
Suehiro, Y.3
-
111
-
-
70349975727
-
Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells
-
Ueno K, Hazama S, Mitomori S, et al.: Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells. Br J Cancer 2009; 101: 1374-1381.
-
(2009)
Br J Cancer
, vol.101
, pp. 1374-1381
-
-
Ueno, K.1
Hazama, S.2
Mitomori, S.3
-
112
-
-
67649238834
-
Intersection of transforming growth factor-beta and Wnt signaling pathways in colorectal cancer and metastasis
-
Carethers JM,: Intersection of transforming growth factor-beta and Wnt signaling pathways in colorectal cancer and metastasis. Gastroenterology 2009; 137: 33-36.
-
(2009)
Gastroenterology
, vol.137
, pp. 33-36
-
-
Carethers, J.M.1
-
113
-
-
74549166032
-
Chromosome 18q deletion as a novel molecular predictor for colorectal cancer with simultaneous hepatic metastasis
-
Tanaka T, Watanabe T, Kitayama J, et al.: Chromosome 18q deletion as a novel molecular predictor for colorectal cancer with simultaneous hepatic metastasis. Diagn Mol Pathol Am J Surg Pathol B 2009; 18: 219-225.
-
(2009)
Diagn Mol Pathol Am J Surg Pathol B
, vol.18
, pp. 219-225
-
-
Tanaka, T.1
Watanabe, T.2
Kitayama, J.3
-
114
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque AT, et al.: DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science (New York, NY) 1996; 271: 350-353.
-
(1996)
Science (New York, NY)
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
-
115
-
-
33845269589
-
Chromosome 18q deletion and Smad4 protein inactivation correlate with liver metastasis: A study matched for T- and N-classification
-
Tanaka T, Watanabe T, Kazama Y, et al.: Chromosome 18q deletion and Smad4 protein inactivation correlate with liver metastasis: A study matched for T- and N-classification. Br J Cancer 2006; 95: 1562-1567.
-
(2006)
Br J Cancer
, vol.95
, pp. 1562-1567
-
-
Tanaka, T.1
Watanabe, T.2
Kazama, Y.3
-
116
-
-
55449088058
-
Prognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancer
-
Togo N, Ohwada S, Sakurai S, et al.: Prognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancer. World J Gastroenterol 2008; 14: 4880-4888.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 4880-4888
-
-
Togo, N.1
Ohwada, S.2
Sakurai, S.3
-
117
-
-
10744228797
-
Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells
-
Sekiya T, Adachi S, Kohu K, et al.: Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells. J Biol Chem 2004; 279: 6840-6846.
-
(2004)
J Biol Chem
, vol.279
, pp. 6840-6846
-
-
Sekiya, T.1
Adachi, S.2
Kohu, K.3
-
118
-
-
67649234580
-
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential
-
Fritzmann J, Morkel M, Besser D, et al.: A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential. Gastroenterology 2009; 137: 165-175.
-
(2009)
Gastroenterology
, vol.137
, pp. 165-175
-
-
Fritzmann, J.1
Morkel, M.2
Besser, D.3
-
119
-
-
23944526062
-
Activation of AKT kinases in cancer: Implications for therapeutic targeting
-
Bellacosa A, Kumar CC, Di Cristofano A, et al.: Activation of AKT kinases in cancer: Implications for therapeutic targeting. Adv Cancer Res 2005; 94: 29-86.
-
(2005)
Adv Cancer Res
, vol.94
, pp. 29-86
-
-
Bellacosa, A.1
Kumar, C.C.2
Di Cristofano, A.3
-
120
-
-
58149503692
-
Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis
-
Rychahou PG, Kang J, Gulhati P, et al.: Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis. Proc Natl Acad Sci USA 2008; 105: 20315-20320.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20315-20320
-
-
Rychahou, P.G.1
Kang, J.2
Gulhati, P.3
-
121
-
-
77949435827
-
Molecular mechanisms to cetuximab and panitumumab in colorectal cancer
-
Bardelli A, Siena S,: Molecular mechanisms to cetuximab and panitumumab in colorectal cancer. J Clin Oncol 2010; 28: 1254-1261.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1254-1261
-
-
Bardelli, A.1
Siena, S.2
-
122
-
-
77949528987
-
KRAS mutation in primary colorectal cancer tumors and related metastases: A potential role in predicition of lung metastasis
-
Cejas P, Lopez-Gomex M, Aguayo C, et al.: KRAS mutation in primary colorectal cancer tumors and related metastases: A potential role in predicition of lung metastasis. PLoS ONE 2009; 4: e1899.
-
(2009)
PLoS ONE
, vol.4
-
-
Cejas, P.1
Lopez-Gomex, M.2
Aguayo, C.3
-
123
-
-
77149163487
-
KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases
-
Nash GM, Gimbel M, Shia J, et al.: KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases. Ann Surg Oncol 2010; 17: 572-578.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 572-578
-
-
Nash, G.M.1
Gimbel, M.2
Shia, J.3
-
124
-
-
71049136170
-
MicroRNAs in colorectal cancer: Translation of molecular biology into clinical application
-
Slaby O, Svoboda M, Michalek J, et al.: MicroRNAs in colorectal cancer: Translation of molecular biology into clinical application. Mol Cancer 2009; 8: 102.
-
(2009)
Mol Cancer
, vol.8
, pp. 102
-
-
Slaby, O.1
Svoboda, M.2
Michalek, J.3
-
125
-
-
39049128249
-
Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer
-
Slaby O, Svoboda M, Fabian P, et al.: Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology 2007; 72: 397-402.
-
(2007)
Oncology
, vol.72
, pp. 397-402
-
-
Slaby, O.1
Svoboda, M.2
Fabian, P.3
-
126
-
-
38749089854
-
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
-
Schetter A, Leung S, Sohn J, et al.: MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008; 299: 425-436.
-
(2008)
JAMA
, vol.299
, pp. 425-436
-
-
Schetter, A.1
Leung, S.2
Sohn, J.3
-
127
-
-
35248889933
-
Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer
-
Mudduluru G, Medved F, Grobholz R, et al.: Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer. Cancer 2007; 110: 1697-1707.
-
(2007)
Cancer
, vol.110
, pp. 1697-1707
-
-
Mudduluru, G.1
Medved, F.2
Grobholz, R.3
-
128
-
-
41749113108
-
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
Asangani IA, Rasheed SA, Nikolova DA, et al.: MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008; 27: 2128-2136.
-
(2008)
Oncogene
, vol.27
, pp. 2128-2136
-
-
Asangani, I.A.1
Rasheed, S.A.2
Nikolova, D.A.3
-
129
-
-
85128713958
-
Prognostic values of microRNAs in colorectal cancer
-
Xi Y, Formentini A, Chien M, et al.: Prognostic values of microRNAs in colorectal cancer. Biomarker Insights 2006; 2: 113-121.
-
(2006)
Biomarker Insights
, vol.2
, pp. 113-121
-
-
Xi, Y.1
Formentini, A.2
Chien, M.3
-
130
-
-
67649425233
-
Over- and under-expressed microRNAs in human colorectal cancer
-
Motoyama K, Inoue H, Takatsuno Y, et al.: Over- and under-expressed microRNAs in human colorectal cancer. Int J Oncol 2009; 34: 1069-1075.
-
(2009)
Int J Oncol
, vol.34
, pp. 1069-1075
-
-
Motoyama, K.1
Inoue, H.2
Takatsuno, Y.3
-
131
-
-
61349141809
-
Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer
-
Wang CJ, Zhou ZG, Wang L, et al.: Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer. Dis Markers 2009; 26: 27-34.
-
(2009)
Dis Markers
, vol.26
, pp. 27-34
-
-
Wang, C.J.1
Zhou, Z.G.2
Wang, L.3
-
132
-
-
51049119231
-
Diagnostic and prognostic microRNAs in stage II colon cancer
-
Schepeler T, Reinert JT, Ostenfeld MS, et al.: Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Res 2008; 68: 6416-6424.
-
(2008)
Cancer Res
, vol.68
, pp. 6416-6424
-
-
Schepeler, T.1
Reinert, J.T.2
Ostenfeld, M.S.3
-
133
-
-
64049086575
-
MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells
-
Strillacci A, Griffoni C, Sansone P, et al.: MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells. Exp Cell Res 2009; 315: 1439-1447.
-
(2009)
Exp Cell Res
, vol.315
, pp. 1439-1447
-
-
Strillacci, A.1
Griffoni, C.2
Sansone, P.3
|