Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 51, 2008, Pages 20315-20320

  Rychahou, Piotr G ^a   Kang, Junghee ^a   Gulhati, Pat ^a   Doan, Hung Q ^a   Chen, L Andy ^a   Xiao, Shu Yuan ^a   Chung, Dai H ^a,b   Evers, B Mark ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

AKT2; Colorectal cancer; Metastasis; Oncogene; Therapeutic target

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE B BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOMA CELL; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; ENZYME REPRESSION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; MALE; MICROMETASTASIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; TUMOR GROWTH; WILD TYPE;

CELL LINE, TUMOR; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; NEOPLASM METASTASIS; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE;

EID: 58149503692     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0810715105     Document Type: Article

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