Role of α5β1 integrin in determining malignant properties of colon carcinoma cells

Cell Growth and Differentiation

Volumn 8, Issue 1, 1997, Pages 83-90

  Gong, Jiangen ^a   Wang, DanHui ^a   Sun, LuZhe ^b   Zborowska, Elizabeth ^c   Willson, James K V ^c   Brattain, Michael G ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; FIBRONECTIN; INTEGRIN; LAMININ;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL ADHESION; COLON CARCINOMA; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN INDUCTION;

ANIMALS; ANTIGENS, CD; CELL ADHESION; COLLAGEN; COLONIC NEOPLASMS; FIBRONECTINS; HUMANS; INTEGRIN ALPHA5; LAMININ; MICE; MICE, NUDE; RECEPTORS, FIBRONECTIN; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0031017019     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Ruoslahti, E. Integrins (Review). J. Clin. Invest., 87: 1-5, 1991.
2. Schwartz, M. A. Signaling by integrins: implications for tumorigenesis. Cancer Res., 53: 1503-1506, 1993.
3. Hynes, R. O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell, 69: 11-25, 1992.
4. Werb, Z., Tremble, P. M., Behrendtsen, O., Crowley, E., and Damsky, C. H. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J. Cell Biol., 109: 877-889, 1989.
5. 1 integrins is a required intermediate in interleukin-1β induction of alkaline phosphatase activity in human osteosarcoma cells. Exp. Cell Res., 183: 207-214, 1989.
6. 1, fibronectin receptors. Exp. Cell Res., 193: 20-26, 1991.
7. Juliano, R. Signal transduction by integrins and its role in the regulation of tumor growth. Cancer Metastasis Rev., 13: 25-30, 1994.
8. Burridge, K., Fath, K., Kelly, T., Nuckolls, G., and Turner, C. Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol., 4: 487-525, 1988.
9. 1 integrin subunit in vitro. J. Cell Biol., 11: 721-729, 1990.
10. Plantefaber, L. C., and Hynes, R. O. Changes in integrin receptors on oncogenically transformed cells. Cell, 56: 281-290, 1989.
11. 1, fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells. Cell, 60: 849-859, 1990.
12. Symington, B. E. Fibronectin receptor overexpression and loss of transformed phenotype in a stable variant of the K562 cell line. Cell Regul., 1: 637-648, 1990.
13. Pignatelli, M., and Bodmer, W. F. Integrin receptor-mediated differentiation and growth inhibition are enhanced by transforming growth factor β in colorectal tumor cells grown in collagen gel. Int. J. Cancer, 44: 518-523, 1989.
14. Ignotz, R. A., and Massague, J. Cell adhesion protein receptors as targets for transforming growth factor β action. Cell, 51: 189-197, 1987.
15. Heino, J., Ignotz, R. A., Hemler, M. E., Grouse, C., and Massague, J. Regulation of cell adhesion receptors by transforming growth factor β. J. Biol. Chem., 264: 380-388, 1989.
16. 1, integrins. Cell Regul., 1: 249-257, 1990.
17. 4 is a laminin receptor. J. Cell Biol., 117: 671-678, 1992.
18. Chantret, I., Barbat, A., Dussaulx, E., Brattain, M. G., and Zwiebaum, A. Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of 20 cell lines. Cancer Res., 48: 1936-1942, 1988.
19. Brattain, M. G., Levine, A. E., Chakrabarty, S., Yeoman, L., Willson, J. K. V., and Long, B. H. Heterogeneity of human colon carcinoma. Cancer Metastasis Rev., 3: 177-191, 1984.
20. Brattain, M. G., Howell, G., Sun, L. Z., and Willson, J. K. Growth factor balance and progression. Curr. Opin. Oncol., 6: 77-81, 1994.
21. Schlechte, J. W., Brattain, M. G., and Boyd, D. Invasion of extracellular matrix by cultured colon cancer: dependence on urokinase receptor display. Cancer Commun., 2: 8-14, 1990.
22. Akiyama, S. K., Yamada, S. S., and Yamada, K. M. Analysis of the role of glycosylation of the human fibronectin receptor. J. Biol. Chem., 264: 18011-18018, 1989.
23. 1, integrins associated with reduced adhesiveness to fibronectin and laminin. Int. J. Cancer, 53: 91-96, 1993.
24. 1 integrins in a weakly metastatic glycosylation mutant. Int. J. Cancer, 44: 343-347, 1989.
25. 6. Cancer Res., 54: 2102-2107, 1994.
26. Ziober, B. L., Willson, J. K. V., Humphrey, L. E., Childress-Fields, K., and Brattain, M. G. Autocrine transforming growth factor α is associated with progression of transformed properties in human colon cancer cells. J. Biol. Chem., 268: 691-698, 1993.
27. 1 in human colon carcinoma FET cells. J. Biol. Chem., 270: 14154-14159, 1995.
28. 1, which regulates DNA synthesis in human fibrosarcoma HT1080 cells. J. Cell. Physiol., 164: 499-508, 1995.
29. Koukoulis, G. K., Virtanen, I., Kothonen, M., Laitinen, L., Quaranta, V., and Gould, V. E. Immunohistochemical localization of integrins in the normal, hyperplastic, and neoplastic breast. Correlations with their functions as receptors and cell adhesion molecules. Am. J. Pathol., 139: 787-799, 1991.
30. 4 integrins in highly invasive and metastatic variants of human prostate carcinoma cells selected by in vitro invasion through reconstituted basement membrane. Clin. & Exp. Metastasis, 11: 391-400, 1993.
31. Mulder, K. M., and Brattain, M. G. Effect of growth stimulatory factors on mitogenicity and c-myc expression in poorly differentiated and well-differentiated human colon carcinoma cells. Mol. Endocrinol., 3: 1215-1222, 1989.
32. Schreiner, C., Fisher, M., Hussein, S., and Juliano, R. L. Increased tumorigenicity of fibronectin receptor-deficient Chinese hamster ovary variants. Cancer Res., 51: 1738-1740, 1991.
33. Varner, J. A., and Juliano, R. L. Adhesion molecules in cancer: the role of integrins. Curr. Opin. Cell Biol., 5: 812-818, 1993.
34. Stallmach, A., Von Lampe, B., Orzechowski, H. D., Matthes, H., and Riecken, E. D. Increased fibronectin-receptor expression in colon carcinoma-derived HT29 cells decreases tumorigenicity in nude mice. Gastroenterology, 106: 19-27, 1994.
35. Symington, B. E. Fibronectin receptor modulates cyclin-dependent kinase activity. J. Biol. Chem., 267: 25-47, 1992.
36. 1, integrin receptor in the proliferative response of quiescent human melanoma cells to fibronectin. Cancer Res., 52: 4499-4506, 1992.
37. 1 expression negatively regulates cell growth: reversal by attachment to fibronectin. Mol. Biol. Cell, 6: 725-740, 1995.
38. Wang, J., Han, W., Zborowska, E., Liang, J., Wang, X-F., Willson, J. K. V., Sun, L-Z., and Brattain, M. G. Reduced expression of transforming growth factor β type I receptor contributes to the malignancy of human colon carcinoma cells. J. Biol. Chem., 271: 17366-17371, 1996.
39. Boyd, D., Florent, G., Chakrabarty, S., Brattain, D. E., and Brattain, M. G. Alterations of the biological characteristics of a colon carcinoma cell line by colon-derived substrata material. Cancer Res., 48: 2825-2831, 1988.
40. Boyd, D. D., Levine, A. E., Brattain, D. E., McKnight, M. K., and Brattain, M. G. Comparison of growth requirements for two human intra- tumoral colon carcinoma cell lines in monolayers and soft agarose. Cancer Res., 48: 2469-2474, 1988.
41. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Rutter, W. J. Isolation of biological active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18: 5294-5299, 1979.
42. 2 in quiescent CBS colon carcinoma cells leads to progression of tumorigenic properties. Cell Growth & Differ., 4: 115-123, 1993.
43. Carmichael, L., DeGraff, W. G., Gazdar, A. F., Minna, J. D., and Mitchell, J. B. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res., 47: 936-942, 1987.
44. Sun, L-Z., Wu, G., Willson, J. K. V., Zborowska, E., Yang, J., Rajkarunanayake, I., Wang, J., Gentry, L. E., Wang, X-F., and Brattain, M. G. Expression of transforming growth factor β type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells. J. Biol. Chem., 269: 26449-26455, 1994.