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Volumn 352, Issue 18, 2010, Pages 3147-3152

Organocatalytic enantioselective strecker synthesis of α-quaternary α-trifluoromethyl amino acids

Author keywords

amino acids; organocatalysis; quaternary stereocenters; Strecker reaction; trifluoromethyl group

Indexed keywords


EID: 78650398782     PISSN: 16154150     EISSN: 16154169     Source Type: Journal    
DOI: 10.1002/adsc.201000666     Document Type: Article
Times cited : (93)

References (118)
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    • For reviews on thioureas, see
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    • The imine with a benzyl protecting group shows a base-catalyzed 1,3-proton shift to give N-benzylidene-2,2,2-trifluoro-1-phenylethanamine as product:,. In the presence of TMSCN no addition occurs, the isomer was obtained with 32% ee
    • The imine with a benzyl protecting group shows a base-catalyzed 1,3-proton shift to give N-benzylidene-2,2,2-trifluoro-1-phenylethanamine as product:, V. A. Soloshonok, M. Yasumoto, J. Fluorine Chem. 2007, 128, 170. In the presence of TMSCN no addition occurs, the isomer was obtained with 32% ee.
    • (2007) J. Fluorine Chem. , vol.128 , pp. 170
    • Soloshonok, V.A.1    Yasumoto, M.2
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    • RWTH University, unpublished results
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    • CCDC 790750 contains the supplementary crystallographic data for the amino nitrile 2a reported in this communication. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via or on application to CCDC, 12 Union Road, Cambridge CB2 1 EZ, UK [fax.: +44-1223/336-033; e-mail: deposit@ ccdc.cam.ac.uk]
    • CCDC 790750 contains the supplementary crystallographic data for the amino nitrile 2a reported in this communication. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via or on application to CCDC, 12 Union Road, Cambridge CB2 1 EZ, UK [fax.: +44-1223/336-033; e-mail: deposit@ ccdc.cam.ac.uk].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.