Generation and reactions of α-trifluoromethyl stabilized aziridinyl anion, a general synthetic precursor for stereospecific construction of α-amino-α-trifluoromethylated quaternary carbon

Tetrahedron Letters

Volumn 44, Issue 33, 2003, Pages 6319-6322

  Yamauchi, Yoshihiro ^a   Kawate, Tomomi ^a   Itahashi, Hiromi ^a   Katagiri, Toshimasa ^a   Uneyama, Kenji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO ACID; AZIRINE DERIVATIVE; BETA AMINO ACID; CARBON; METHYL GROUP;

ARTICLE; DIASTEREOISOMER; METHYLATION; MOLECULAR STABILITY; PRECURSOR; PROTON TRANSPORT; REACTION OPTIMIZATION; STEREOCHEMISTRY; STEREOSPECIFICITY; X RAY CRYSTALLOGRAPHY;

EID: 0042347784     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(03)01520-X     Document Type: Article

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26. 25=-0.4 (diastereo mixture, c 1.06, MeOH).
27. 25=-60.7 (c 1.16, MeOH).
28. 0). Reflection/parameter ratio was 6.31, Goodness of fit indicator was 1.73. Max shift/error in final cycle was 0.06.