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Volumn 349, Issue 4-5, 2007, Pages 759-764

Metal-free, enantioselective strecker reactions catalyzed by chiral BINOL and TADDOL catalysts

Author keywords

Amino acids; BINOL phosphate; Br nsted acid; Hydrocyanation; Strecker reaction; TADDOL

Indexed keywords


EID: 34250780205     PISSN: 16154150     EISSN: 15213897     Source Type: Journal    
DOI: 10.1002/adsc.200600405     Document Type: Article
Times cited : (126)

References (84)
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    • Solutions of hydrogen cyanide were generated prior to the addition by combination of equimolar amounts of TMSCN and methanol in toluene for 1 h
    • Solutions of hydrogen cyanide were generated prior to the addition by combination of equimolar amounts of TMSCN and methanol in toluene for 1 h.
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    • Enantioselectivities decreased in the case of ethyl-keto imines and aliphatic ketoimines, for example, 2-(4-methoxybenzylamino)-2- phenylbutanenitrile was obtained in 40% ee, 2-(4-methoxy-benzylamino)-2,3- dimethylbutanenitrile was obtained in 12, ee
    • Enantioselectivities decreased in the case of ethyl-keto imines and aliphatic ketoimines, for example, 2-(4-methoxybenzylamino)-2- phenylbutanenitrile was obtained in 40% ee, 2-(4-methoxy-benzylamino)-2,3- dimethylbutanenitrile was obtained in 12 % ee.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.