Determination of acetaminophen's solubility in poly(ethylene oxide) by rheological, thermal and microscopic methods

International Journal of Pharmaceutics

Volumn 403, Issue 1-2, 2011, Pages 83-89

  Yang, Min ^a   Wang, Peng ^b,c   Suwardie, Herman ^d   Gogos, Costas ^a,d  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^b University of Rhode Island   (United States)

^c UNIVERSITY OF RHODE ISLAND   (United States)

^d Polymer Processing Institute   (United States)

Author keywords

Acetaminophen paracetamol; Glass transition; Hot melt mixing; Poly(ethylene oxide) (PEO); Rheology; Solubility

Indexed keywords

MACROGOL; PARACETAMOL;

ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; EXPERIMENTAL STUDY; FLOW KINETICS; PRIORITY JOURNAL; ROOM TEMPERATURE; TEMPERATURE MEASUREMENT; THERMAL ANALYSIS; THERMODYNAMICS;

ACETAMINOPHEN; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; HOT TEMPERATURE; MICROSCOPY; PHASE TRANSITION; POLYETHYLENE GLYCOLS; RHEOLOGY; SOLUBILITY; SURFACE PROPERTIES;

EID: 78650180194     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.10.026     Document Type: Article

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