Influence of sulfobutyl ether β-cyclodextrin (Captisol®) on the dissolution properties of a poorly soluble drug from extrudates prepared by hot-melt extrusion

International Journal of Pharmaceutics

Volumn 350, Issue 1-2, 2008, Pages 188-196

  Fukuda, Mamoru ^a   Miller, Dave A ^a   Peppas, Nicholas A ^a   McGinity, James W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Captisol ; Hot melt extrusion; Ketoprofen; Poorly water soluble drug; Sulfobutyl ether cyclodextrin

Indexed keywords

BETA CYCLODEXTRIN; BETA CYCLODEXTRIN SULFOBUTYL ETHER; KETOPROFEN;

ARTICLE; COMPLEX FORMATION; DISSOLUTION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STRUCTURE; FREEZE DRYING; GRINDING; HEATING; HUMIDITY; IN VITRO STUDY; MELTING POINT; MOISTURE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

BETA-CYCLODEXTRINS; KETOPROFEN; MAGNETIC RESONANCE SPECTROSCOPY; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; X-RAY DIFFRACTION;

EID: 38349153803     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.08.038     Document Type: Article

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