Crystal growth formation in melt extrudates

International Journal of Pharmaceutics

Volumn 341, Issue 1-2, 2007, Pages 162-172

  Bruce, Caroline ^a   Fegely, Kurt A ^b   Rajabi Siahboomi, Ali R ^b   McGinity, James W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b Colorcon ^*  (United States)

Author keywords

Acryl EZE ; Eudragit L100 55; Guaifenesin; Hot melt extrusion; Matrix tablets; Physical stability; Recrystallization

Indexed keywords

BUFFER; EUDRAGIT; GUAIFENESIN; MACROGOL; MACROGOL 3350; PHOSPHATE; POLOXAMER; POLYCARBOPHIL; POLYMER;

ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG RELEASE; DRUG SOLUBILITY; GLASS TRANSITION TEMPERATURE; HYDROPHILICITY; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ACRYLIC RESINS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CITRATES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; GUAIFENESIN; HUMIDITY; HYDROGEN-ION CONCENTRATION; KINETICS; MICROSCOPY, ELECTRON, SCANNING; PLASTICIZERS; POLYMERS; POWDER DIFFRACTION; SOLUBILITY; SURFACE PROPERTIES; TABLETS, ENTERIC-COATED; TALC; TECHNOLOGY, PHARMACEUTICAL; TRANSITION TEMPERATURE; WATER;

EID: 34447623038     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.04.008     Document Type: Article

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