Stabilization of hot-melt extrusion formulations containing solid solutions using polymer blends

AAPS PharmSciTech

Volumn 8, Issue 2, 2007, Pages

  Prodduturi, Suneela ^a   Urman, Kevin L ^b   Otaigbe, Joshua U ^b   Repka, Michael A ^c  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b Virginia Polytechnic Institute and State University   (United States)

^c UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Hot melt extrusion; Physical stability; Physicochemical characterization; Polymers; Solid solution

Indexed keywords

CLOTRIMAZOLE; POLYMER; CELLULOSE; DRUG DERIVATIVE; HYDROXYPROPYLCELLULOSE; MACROGOL DERIVATIVE;

ADHESION; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; FILM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; IN VITRO STUDY; MOISTURE; PHYSICAL CHEMISTRY; SOLID; TEMPERATURE; X RAY DIFFRACTION; BIOMECHANICS; CHEMISTRY; SOLUBILITY;

BIOMECHANICS; CALORIMETRY, DIFFERENTIAL SCANNING; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLOTRIMAZOLE; DRUG STABILITY; POLYETHYLENE GLYCOLS; SOLUBILITY; TEMPERATURE; X-RAY DIFFRACTION;

EID: 34447296485     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt0802027     Document Type: Article

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