-
1
-
-
9144272819
-
Using RNAi to catch Drosophila genes in a web of interactions: Insights into cancer research
-
Dasgupta R, Perrimon N: Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research. Oncogene 23(51), 8359-8365 (2004).
-
(2004)
Oncogene
, vol.23
, Issue.51
, pp. 8359-8365
-
-
Dasgupta, R.1
Perrimon, N.2
-
2
-
-
36148942524
-
Transgenesis upgrades for Drosophila melanogaster
-
Venken KJ, Bellen HJ: Transgenesis upgrades for Drosophila melanogaster. Development 134(20), 3571-3584 (2007).
-
(2007)
Development
, vol.134
, Issue.20
, pp. 3571-3584
-
-
Venken, K.J.1
Bellen, H.J.2
-
3
-
-
67349098844
-
Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster
-
Venken KJ, Carlson JW, Schulze KL et al.: Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster. Nat. Methods 6(6), 431-434 (2009).
-
(2009)
Nat. Methods
, vol.6
, Issue.6
, pp. 431-434
-
-
Venken, K.J.1
Carlson, J.W.2
Schulze, K.L.3
-
4
-
-
0037096880
-
A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin
-
Casanova ML, Larcher F, Casanova B et al.: A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin. Carcinogenesis Cancer Res. 62(12), 3402-3407 (2002).
-
(2002)
Carcinogenesis Cancer Res.
, vol.62
, Issue.12
, pp. 3402-3407
-
-
Casanova, M.L.1
Larcher, F.2
Casanova, B.3
-
5
-
-
0028000009
-
Sutherland RL: Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2
-
Janes PW, Daly RJ, deFazio A, Sutherland RL: Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2. Oncogene 9(12), 3601-3608 (1994).
-
(1994)
Oncogene
, vol.9
, Issue.12
, pp. 3601-3608
-
-
Janes, P.W.1
Daly, R.J.2
Defazio, A.3
-
6
-
-
0033863510
-
RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells
-
Martinez-Lacaci I, Kannan S, De Santis M et al.: RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells. Int. J. Cancer 88(1), 44-52 (2000).
-
(2000)
Int. J. Cancer
, vol.88
, Issue.1
, pp. 44-52
-
-
Martinez-Lacaci, I.1
Kannan, S.2
De Santis, M.3
-
7
-
-
0032894310
-
Several levels of EGF receptor signaling during photoreceptor specifcation in wild-type, Ellipse, and null mutant
-
Lesokhin AM, Yu SY, Katz J, Baker NE: Several levels of EGF receptor signaling during photoreceptor specifcation in wild-type, Ellipse, and null mutant Drosophila Dev. Biol. 205(1), 129-144 (1999).
-
(1999)
Drosophila Dev. Biol.
, vol.205
, Issue.1
, pp. 129-144
-
-
Lesokhin, A.M.1
Yu, S.Y.2
Katz, J.3
Baker, N.E.4
-
8
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand AH, Perrimon N: Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118(2), 401-415 (1993).
-
(1993)
Development
, vol.118
, Issue.2
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
9
-
-
34250683854
-
The RNAi pathway initiated by Dicer-2 in Drosophila
-
Kim K, Lee YS, Harris D, Nakahara K, Carthew RW: The RNAi pathway initiated by Dicer-2 in Drosophila. Cold Spring Harb. Symp. Quant. Biol. 71, 39-44 (2006).
-
(2006)
Cold Spring Harb. Symp. Quant. Biol.
, vol.71
, pp. 39-44
-
-
Kim, K.1
Lee, Y.S.2
Harris, D.3
Nakahara, K.4
Carthew, R.W.5
-
10
-
-
77953626646
-
Genomic screening with RNAi: Results and challenges
-
Mohr S, Bakal C, Perrimon N: Genomic screening with RNAi: results and challenges. Annu. Rev. Biochem. 79, 37-64 (2010).
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 37-64
-
-
Mohr, S.1
Bakal, C.2
Perrimon, N.3
-
11
-
-
18244400410
-
Functional genomic analysis of the Wnt-wingless signaling pathway
-
DasGupta R, Kaykas A, Moon RT, Perrimon N: Functional genomic analysis of the Wnt-wingless signaling pathway. Science 308(5723), 826-833 (2005).
-
(2005)
Science
, vol.308
, Issue.5723
, pp. 826-833
-
-
Dasgupta, R.1
Kaykas, A.2
Moon, R.T.3
Perrimon, N.4
-
12
-
-
0037470952
-
Identifcation of Hedgehog pathway components by RNAi in Drosophila cultured cells
-
Lum L, Yao S, Mozer B et al.: Identifcation of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299(5615), 2039-2045 (2003).
-
(2003)
Science
, vol.299
, Issue.5615
, pp. 2039-2045
-
-
Lum, L.1
Yao, S.2
Mozer, B.3
-
13
-
-
28444451148
-
A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway
-
Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N: A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nat. Genet. 37(12), 1323-1332 (2005).
-
(2005)
Nat. Genet.
, vol.37
, Issue.12
, pp. 1323-1332
-
-
Nybakken, K.1
Vokes, S.A.2
Lin, T.Y.3
McMahon, A.P.4
Perrimon, N.5
-
14
-
-
73549093581
-
A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1
-
Cully M, Genevet A, Warne P et al.: A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1. Mol. Cell. Biol. 30(2), 481-495.
-
Mol. Cell. Biol.
, vol.30
, Issue.2
, pp. 481-495
-
-
Cully, M.1
Genevet, A.2
Warne, P.3
-
15
-
-
33750887331
-
A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling
-
Friedman A, Perrimon N: A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature 444(7116), 230-234 (2006).
-
(2006)
Nature
, vol.444
, Issue.7116
, pp. 230-234
-
-
Friedman, A.1
Perrimon, N.2
-
16
-
-
0021918375
-
Intrinsic growth control in the imaginal primordia of Drosophila, and the autonomous action of a lethal mutation causing overgrowth
-
Bryant PJ, Levinson P: Intrinsic growth control in the imaginal primordia of Drosophila, and the autonomous action of a lethal mutation causing overgrowth. Dev. Biol. 107(2), 355-363 (1985).
-
(1985)
Dev. Biol.
, vol.107
, Issue.2
, pp. 355-363
-
-
Bryant, P.J.1
Levinson, P.2
-
17
-
-
0025941465
-
The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions
-
Woods DF, Bryant PJ: The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell 66(3), 451-464 (1991).
-
(1991)
Cell
, vol.66
, Issue.3
, pp. 451-464
-
-
Woods, D.F.1
Bryant, P.J.2
-
18
-
-
18144420564
-
A Drosophila model of multiple endocrine neoplasia type 2
-
Read RD, Goodfellow PJ, Mardis ER et al.: A Drosophila model of multiple endocrine neoplasia type 2. Genetics 171(3), 1057-1081 (2005).
-
(2005)
Genetics
, vol.171
, Issue.3
, pp. 1057-1081
-
-
Read, R.D.1
Goodfellow, P.J.2
Mardis, E.R.3
-
19
-
-
35948935013
-
Differing Src signaling levels have distinct outcomes in Drosophila
-
Vidal M, Warner S, Read R, Cagan RL: Differing Src signaling levels have distinct outcomes in Drosophila Cancer Res. 67(21), 10278-10285 (2007).
-
(2007)
Cancer Res.
, vol.67
, Issue.21
, pp. 10278-10285
-
-
Vidal, M.1
Warner, S.2
Read, R.3
Cagan, R.L.4
-
20
-
-
41649092988
-
Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer
-
Acharya CR, Hsu DS, Anders CK et al.: Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA 299(13), 1574-1587 (2008).
-
(2008)
JAMA
, vol.299
, Issue.13
, pp. 1574-1587
-
-
Acharya, C.R.1
Hsu, D.S.2
Anders, C.K.3
-
21
-
-
0033583220
-
C-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
-
Biscardi JS, Maa MC, Tice DA et al.: c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J. Biol. Chem. 274(12), 8335-8343 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.12
, pp. 8335-8343
-
-
Biscardi, J.S.1
Maa, M.C.2
Tice, D.A.3
-
22
-
-
0035823484
-
Functional analysis of Csk and CHK kinases in breast
-
Bougeret C, Jiang S, Keydar I, Avraham H: Functional analysis of Csk and CHK kinases in breast Cancer Cells. J. Biol. Chem. 276(36), 33711-33720 (2001).
-
(2001)
Cancer Cells. J. Biol. Chem.
, vol.276
, Issue.36
, pp. 33711-33720
-
-
Bougeret, C.1
Jiang, S.2
Keydar, I.3
Avraham, H.4
-
23
-
-
34249325876
-
Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: C-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior
-
Dimri M, Naramura M, Duan L et al.: Modeling breast cancer-associated c-Src and EGFR overexpression in human MECs: c-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive behavior. Cancer Res. 67(9), 4164-4172 (2007).
-
(2007)
Cancer Res.
, vol.67
, Issue.9
, pp. 4164-4172
-
-
Dimri, M.1
Naramura, M.2
Duan, L.3
-
24
-
-
34249306702
-
Epidermal growth factor directs sex-specifc steroid signaling through Src activation
-
Hitosugi T, Sasaki K, Sato M, Suzuki Y, Umezawa Y: Epidermal growth factor directs sex-specifc steroid signaling through Src activation. J. Biol. Chem. 282(14), 10697-10706 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.14
, pp. 10697-10706
-
-
Hitosugi, T.1
Sasaki, K.2
Sato, M.3
Suzuki, Y.4
Umezawa, Y.5
-
25
-
-
34249326610
-
C-Src modulates ErbB2 and ErbB3 heterocomplex formation and function
-
Ishizawar RC, Miyake T, Parsons SJ: c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function. Oncogene 26(24), 3503-3510 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.24
, pp. 3503-3510
-
-
Ishizawar, R.C.1
Miyake, T.2
Parsons, S.J.3
-
26
-
-
33847332146
-
EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells
-
Moiseeva EP, Heukers R, Manson MM: EGFR and Src are involved in indole-3-carbinol-induced death and cell cycle arrest of human breast cancer cells. Carcinogenesis 28(2), 435-445 (2007).
-
(2007)
Carcinogenesis
, vol.28
, Issue.2
, pp. 435-445
-
-
Moiseeva, E.P.1
Heukers, R.2
Manson, M.M.3
-
27
-
-
16444382989
-
ErbB2 promotes Src synthesis and stability: Novel mechanisms of Src activation that confer breast cancer metastasis
-
Tan M, Li P, Klos KS et al.: ErbB2 promotes Src synthesis and stability: novel mechanisms of Src activation that confer breast cancer metastasis. Cancer Res. 65(5), 1858-1867 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.5
, pp. 1858-1867
-
-
Tan, M.1
Li, P.2
Klos, K.S.3
-
28
-
-
75949092766
-
SRC-3d4 mediates the interaction of EGFR with FAK to promote cell migration
-
Long W, Yi P, Amazit L et al.: SRC-3d4 mediates the interaction of EGFR with FAK to promote cell migration. Mol. Cell 37(3), 321-332 (2010).
-
(2010)
Mol. Cell
, vol.37
, Issue.3
, pp. 321-332
-
-
Long, W.1
Yi, P.2
Amazit, L.3
-
29
-
-
60549101931
-
Specifc cross-talk between epidermal growth factor receptor and integrin avb5 promotes carcinoma cell invasion and metastasis
-
Ricono JM, Huang M, Barnes LA et al.: Specifc cross-talk between epidermal growth factor receptor and integrin avb5 promotes carcinoma cell invasion and metastasis. Cancer Res. 69(4), 1383-1391 (2009).
-
(2009)
Cancer Res.
, vol.69
, Issue.4
, pp. 1383-1391
-
-
Ricono, J.M.1
Huang, M.2
Barnes, L.A.3
-
30
-
-
33745402375
-
Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells
-
Hiscox S, Morgan L, Green TP et al.: Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. Breast Cancer Res. Treat. 97(3), 263-274 (2006).
-
(2006)
Breast Cancer Res. Treat.
, vol.97
, Issue.3
, pp. 263-274
-
-
Hiscox, S.1
Morgan, L.2
Green, T.P.3
-
31
-
-
4544235743
-
C-Src and cooperating partners in human cancer
-
Ishizawar R, Parsons SJ: c-Src and cooperating partners in human cancer. Cancer Cell 6(3), 209-214 (2004).
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 209-214
-
-
Ishizawar, R.1
Parsons, S.J.2
-
32
-
-
0038393116
-
Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215
-
Vadlamudi RK, Sahin AA, Adam L, Wang RA, Kumar R: Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215. FEBS Lett. 543(1-3), 76-80 (2003).
-
(2003)
FEBS Lett.
, vol.543
, Issue.1-3
, pp. 76-80
-
-
Vadlamudi, R.K.1
Sahin, A.A.2
Adam, L.3
Wang, R.A.4
Kumar, R.5
-
33
-
-
6844259884
-
Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential
-
Mao W, Irby R, Coppola D et al.: Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential. Oncogene 15(25), 3083-3090 (1997). (Pubitemid 28043487)
-
(1997)
Oncogene
, vol.15
, Issue.25
, pp. 3083-3090
-
-
Mao, W.1
Irby, R.2
Coppola, D.3
Fu, L.4
Wloch, M.5
Turner, J.6
Yu, H.7
Garcia, R.8
Jove, R.9
Yeatman, T.J.10
-
34
-
-
31444452060
-
Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing
-
Ferres-Marco D, Gutierrez-Garcia I, Vallejo DM et al.: Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing. Nature 439(7075), 430-436 (2006).
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 430-436
-
-
Ferres-Marco, D.1
Gutierrez-Garcia, I.2
Vallejo, D.M.3
-
36
-
-
0032909884
-
The gene search system A method for effcient detection and rapid molecular identifcation of genes in Drosophila melanogaster
-
Toba G, Ohsako T, Miyata N et al.: The gene search system. A method for effcient detection and rapid molecular identifcation of genes in Drosophila melanogaster. Genetics 151(2), 725-737 (1999).
-
(1999)
Genetics
, vol.151
, Issue.2
, pp. 725-737
-
-
Toba, G.1
Ohsako, T.2
Miyata, N.3
-
37
-
-
3242677215
-
Gene expression systems in Drosophila: A synthesis of time and space
-
McGuire SE, Roman G, Davis RL: Gene expression systems in Drosophila: a synthesis of time and space. Trends Genet. 20(8), 384-391 (2004).
-
(2004)
Trends Genet.
, vol.20
, Issue.8
, pp. 384-391
-
-
McGuire, S.E.1
Roman, G.2
Davis, R.L.3
-
38
-
-
65349121368
-
Notch signalling in cancer stem cells
-
Bolos V, Blanco M, Medina V et al.: Notch signalling in cancer stem cells. Clin. Transl. Oncol. 11(1), 11-19 (2009).
-
(2009)
Clin. Transl. Oncol.
, vol.11
, Issue.1
, pp. 11-19
-
-
Bolos, V.1
Blanco, M.2
Medina, V.3
-
39
-
-
36248953716
-
Mammary stem cells and breast cancer-role of Notch signalling
-
Farnie G, Clarke RB: Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev. 3(2), 169-175 (2007).
-
(2007)
Stem Cell Rev.
, vol.3
, Issue.2
, pp. 169-175
-
-
Farnie, G.1
Clarke, R.B.2
-
40
-
-
73549092704
-
Emerging role of Notch signaling in epidermal differentiation and skin cancer
-
Panelos J, Massi D: Emerging role of Notch signaling in epidermal differentiation and skin cancer. Cancer Biol. Ther. 8(21), 1986-1993 (2009).
-
(2009)
Cancer Biol. Ther.
, vol.8
, Issue.21
, pp. 1986-1993
-
-
Panelos, J.1
Massi, D.2
-
41
-
-
27644593284
-
Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth
-
Moberg KH, Schelble S, Burdick SK, Hariharan IK: Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth. Dev. Cell. 9(5), 699-710 (2005).
-
(2005)
Dev. Cell.
, vol.9
, Issue.5
, pp. 699-710
-
-
Moberg, K.H.1
Schelble, S.2
Burdick, S.K.3
Hariharan, I.K.4
-
42
-
-
27644498439
-
Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila
-
Thompson BJ, Mathieu J, Sung HH et al.: Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev. Cell. 9(5), 711-720 (2005).
-
(2005)
Dev. Cell.
, vol.9
, Issue.5
, pp. 711-720
-
-
Thompson, B.J.1
Mathieu, J.2
Sung, H.H.3
-
43
-
-
0242641565
-
Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
-
Brumby AM, Richardson HE: Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J. 22(21), 5769-5779 (2003).
-
(2003)
EMBO J.
, vol.22
, Issue.21
, pp. 5769-5779
-
-
Brumby, A.M.1
Richardson, H.E.2
-
44
-
-
0032561176
-
The pipsqueak protein of Drosophila melanogaster binds to GAGA sequences through a novel DNA-binding domain
-
Lehmann M, Siegmund T, Lintermann KG, Korge G: The pipsqueak protein of Drosophila melanogaster binds to GAGA sequences through a novel DNA-binding domain. J. Biol. Chem. 273(43), 28504-28509 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.43
, pp. 28504-28509
-
-
Lehmann, M.1
Siegmund, T.2
Lintermann, K.G.3
Korge, G.4
-
45
-
-
0028178116
-
Lola encodes a putative transcription factor required for axon growth and guidance in Drosophila
-
Giniger E, Tietje K, Jan LY, Jan YN: lola encodes a putative transcription factor required for axon growth and guidance in Drosophila. Development 120(6), 1385-1398 (1994).
-
(1994)
Development
, vol.120
, Issue.6
, pp. 1385-1398
-
-
Giniger, E.1
Tietje, K.2
Jan, L.Y.3
Jan, Y.N.4
-
46
-
-
0038692959
-
Trl-GAGA directly interacts with lola like and both are part of the repressive complex of Polycomb group of genes
-
Mishra K, Chopra VS, Srinivasan A, Mishra RK: Trl-GAGA directly interacts with lola like and both are part of the repressive complex of Polycomb group of genes. Mech. Dev. 120(6), 681-689 (2003).
-
(2003)
Mech. Dev.
, vol.120
, Issue.6
, pp. 681-689
-
-
Mishra, K.1
Chopra, V.S.2
Srinivasan, A.3
Mishra, R.K.4
-
47
-
-
61449245596
-
A Drosophila model for EGFR-Ras and PI3K-dependent human glioma
-
Read RD, Cavenee WK, Furnari FB, Thomas JB: A Drosophila model for EGFR-Ras and PI3K-dependent human glioma. PLoS Genet. 5(2), E1000374 (2009).
-
(2009)
PLoS Genet.
, vol.5
, Issue.2
-
-
Read, R.D.1
Cavenee, W.K.2
Furnari, F.B.3
Thomas, J.B.4
-
48
-
-
34250212943
-
Genetic control of heart function and aging in Drosophila
-
Ocorr K, Perrin L, Lim HY et al.: Genetic control of heart function and aging in Drosophila. Trends Cardiovasc. Med. 17(5), 177-182 (2007).
-
(2007)
Trends Cardiovasc. Med.
, vol.17
, Issue.5
, pp. 177-182
-
-
Ocorr, K.1
Perrin, L.2
Lim, H.Y.3
-
49
-
-
9644278037
-
Insulin regulation of heart function in aging fruit fies
-
Wessells RJ, Fitzgerald E, Cypser JR, Tatar M, Bodmer R: Insulin regulation of heart function in aging fruit fies. Nat. Genet. 36(12), 1275-1281 (2004).
-
(2004)
Nat. Genet.
, vol.36
, Issue.12
, pp. 1275-1281
-
-
Wessells, R.J.1
Fitzgerald, E.2
Cypser, J.R.3
Tatar, M.4
Bodmer, R.5
-
50
-
-
7644239149
-
Drosophila, an emerging model for cardiac disease
-
Bier E, Bodmer R: Drosophila, an emerging model for cardiac disease. Gene 342(1), 1-11 (2004).
-
(2004)
Gene
, vol.342
, Issue.1
, pp. 1-11
-
-
Bier, E.1
Bodmer, R.2
-
51
-
-
0031805934
-
Heart development in Drosophila and vertebrates: Conservation of molecular mechanisms
-
Bodmer R, Venkatesh T V, Heart development in Drosophila and vertebrates: conservation of molecular mechanisms. Dev. Genet. 22(3), 181-186 (1998).
-
(1998)
Dev. Genet.
, vol.22
, Issue.3
, pp. 181-186
-
-
Bodmer, R.1
Venkatesh, T.V.2
-
52
-
-
80055102334
-
Fluorescent labeling of Drosophila heart structures
-
pii
-
Alayari NN, Vogler G, Taghli-Lamallem O et al.: Fluorescent labeling of Drosophila heart structures. J. Vis. Exp. 32, pii 1423 (2009).
-
(2009)
J. Vis. Exp.
, vol.32
, pp. 1423
-
-
Alayari, N.N.1
Vogler, G.2
Taghli-Lamallem, O.3
-
53
-
-
34247257761
-
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging
-
Ocorr K, Reeves NL, Wessells RJ et al.: KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proc. Natl Acad. Sci. USA 104(10), 3943-3948 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, Issue.10
, pp. 3943-3948
-
-
Ocorr, K.1
Reeves, N.L.2
Wessells, R.J.3
-
54
-
-
34249829247
-
Age-related cardiac deterioration: Insights from Drosophila
-
DOI 10.2741/2047
-
Wessells RJ, Bodmer R: Age-related cardiac deterioration: insights from Drosophila. Front. Biosci. 12, 39-48 (2007). (Pubitemid 46852826)
-
(2007)
Frontiers in Bioscience
, vol.12
, Issue.1
, pp. 39-48
-
-
Wessells, R.J.1
Bodmer, R.2
-
55
-
-
4143106947
-
Differential expression of Csk homologous kinase (CHK) in normal brain and brain tumors
-
Kim SO, Avraham S, Jiang S et al.: Differential expression of Csk homologous kinase (CHK) in normal brain and brain tumors. Cancer 101(5), 1018-1027 (2004).
-
(2004)
Cancer
, vol.101
, Issue.5
, pp. 1018-1027
-
-
Kim, S.O.1
Avraham, S.2
Jiang, S.3
-
56
-
-
0037052544
-
Ablation of insulin-producing neurons in fies: Growth and diabetic phenotypes
-
Rulifson EJ, Kim SK, Nusse R: Ablation of insulin-producing neurons in fies: growth and diabetic phenotypes. Science 296(5570), 1118-1120 (2002).
-
(2002)
Science
, vol.296
, Issue.5570
, pp. 1118-1120
-
-
Rulifson, E.J.1
Kim, S.K.2
Nusse, R.3
-
57
-
-
0025865768
-
Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas
-
Khosla S, Patel VM, Hay ID et al.: Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas. J. Clin. Invest. 87(5), 1691-1699 (1991).
-
(1991)
J. Clin. Invest.
, vol.87
, Issue.5
, pp. 1691-1699
-
-
Khosla, S.1
Patel, V.M.2
Hay, I.D.3
-
58
-
-
0027231568
-
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
-
Mulligan LM, Kwok JB, Healey CS et al.: Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature 363(6428), 458-460 (1993).
-
(1993)
Nature
, vol.363
, Issue.6428
, pp. 458-460
-
-
Mulligan, L.M.1
Kwok, J.B.2
Healey, C.S.3
-
59
-
-
2442534006
-
Diagnosis and management of medullary thyroid carcinoma
-
Massoll N, Mazzaferri EL: Diagnosis and management of medullary thyroid carcinoma. Clin. Lab. Med. 24(1), 49-83 (2004).
-
(2004)
Clin. Lab. Med.
, vol.24
, Issue.1
, pp. 49-83
-
-
Massoll, N.1
Mazzaferri, E.L.2
-
60
-
-
0037115405
-
ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, effciently blocks oncogenic RET kinases
-
Carlomagno F, Vitagliano D, Guida T et al.: ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, effciently blocks oncogenic RET kinases. Cancer Res. 62(24), 7284-7290 (2002).
-
(2002)
Cancer Res.
, vol.62
, Issue.24
, pp. 7284-7290
-
-
Carlomagno, F.1
Vitagliano, D.2
Guida, T.3
-
61
-
-
77649214078
-
Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer
-
Wells SA Jr, Gosnell JE, Gagel RF et al.: Vandetanib for the treatment of patients with locally advanced or metastatic hereditary medullary thyroid cancer. J. Clin. Oncol. 28(5), 767-772 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.5
, pp. 767-772
-
-
Wells Jr., S.A.1
Gosnell, J.E.2
Gagel, R.F.3
-
62
-
-
41049102573
-
Identifcation of small molecules rescuing Fragile X syndrome phenotypes in Drosophila
-
Chang S, Bray SM, Li Z et al.: Identifcation of small molecules rescuing Fragile X syndrome phenotypes in Drosophila. Nat. Chem. Biol. 4(4), 256-263 (2008).
-
(2008)
Nat. Chem. Biol.
, vol.4
, Issue.4
, pp. 256-263
-
-
Chang, S.1
Bray, S.M.2
Li, Z.3
-
63
-
-
33746866693
-
Dynamic translational and proteasomal regulation of Fragile X mental retardation protein controls mGluR-dependent long-term depression
-
Hou L, Antion MD, Hu D et al.: Dynamic translational and proteasomal regulation of Fragile X mental retardation protein controls mGluR-dependent long-term depression. Neuron 51(4), 441-454 (2006).
-
(2006)
Neuron
, vol.51
, Issue.4
, pp. 441-454
-
-
Hou, L.1
Antion, M.D.2
Hu, D.3
-
64
-
-
1642336232
-
Metabotropic glutamate receptor activation regulates Fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses
-
Antar LN, Afroz R, Dictenberg JB, Carroll RC, Bassell GJ: Metabotropic glutamate receptor activation regulates Fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. J. Neurosci. 24(11), 2648-2655 (2004).
-
(2004)
J. Neurosci.
, vol.24
, Issue.11
, pp. 2648-2655
-
-
Antar, L.N.1
Afroz, R.2
Dictenberg, J.B.3
Carroll, R.C.4
Bassell, G.J.5
-
65
-
-
0345528532
-
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
-
Weiler IJ, Irwin SA, Klintsova AY et al.: Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc. Natl Acad. Sci. USA 94(10), 5395-5400 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, Issue.10
, pp. 5395-5400
-
-
Weiler, I.J.1
Irwin, S.A.2
Klintsova, A.Y.3
-
66
-
-
33746533924
-
A-synuclein blocks ER-Golgi traffc and Rab1 rescues neuron loss in Parkinson's models
-
Cooper AA, Gitler AD, Cashikar A et al.: A-synuclein blocks ER-Golgi traffc and Rab1 rescues neuron loss in Parkinson's models. Science 313(5785), 324-328 (2006).
-
(2006)
Science
, vol.313
, Issue.5785
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
-
67
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark IE, Dodson MW, Jiang C et al.: Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441(7097), 1162-1166 (2006).
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
-
68
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J, Lee SB, Lee S et al.: Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441(7097), 1157-1161 (2006).
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
-
69
-
-
17844406856
-
A-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
-
Chen L, Feany MB: A-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat. Neurosci. 8(5), 657-663 (2005).
-
(2005)
Nat. Neurosci.
, vol.8
, Issue.5
, pp. 657-663
-
-
Chen, L.1
Feany, M.B.2
-
70
-
-
0347719407
-
Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster
-
Hanai S, Kanai M, Ohashi S et al.: Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster. Proc. Natl Acad. Sci. USA 101(1), 82-86 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.1
, pp. 82-86
-
-
Hanai, S.1
Kanai, M.2
Ohashi, S.3
-
71
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B: Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron 37(6), 911-924 (2003).
-
(2003)
Neuron
, vol.37
, Issue.6
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
72
-
-
0036852712
-
Pharmacological prevention of Parkinson disease in Drosophila
-
Auluck PK, Bonini NM: Pharmacological prevention of Parkinson disease in Drosophila. Nat. Med. 8(11), 1185-1186 (2002).
-
(2002)
Nat. Med.
, vol.8
, Issue.11
, pp. 1185-1186
-
-
Auluck, P.K.1
Bonini, N.M.2
-
73
-
-
0036468432
-
Chaperone suppression of a-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM: Chaperone suppression of a-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295(5556), 865-868 (2002).
-
(2002)
Science
, vol.295
, Issue.5556
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowski, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
74
-
-
0034597833
-
Identifcation of genes that modify ataxin-1-induced neurodegeneration
-
Fernandez-Funez P, Nino-Rosales ML, de Gouyon B et al.: Identifcation of genes that modify ataxin-1-induced neurodegeneration. Nature 408(6808), 101-106 (2000).
-
(2000)
Nature
, vol.408
, Issue.6808
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
De Gouyon, B.3
-
75
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany MB, Bender WW: A Drosophila model of Parkinson's disease. Nature 404(6776), 394-398 (2000).
-
(2000)
Nature
, vol.404
, Issue.6776
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
76
-
-
37549004790
-
Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm
-
Romero E, Cha GH, Verstreken P et al.: Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm. Neuron 57(1), 27-40 (2008).
-
(2008)
Neuron
, vol.57
, Issue.1
, pp. 27-40
-
-
Romero, E.1
Cha, G.H.2
Verstreken, P.3
-
77
-
-
34248994604
-
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
-
Sarkar S, Perlstein EO, Imarisio S et al.: Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. Nat. Chem. Biol. 3(6), 331-338 (2007).
-
(2007)
Nat. Chem. Biol.
, vol.3
, Issue.6
, pp. 331-338
-
-
Sarkar, S.1
Perlstein, E.O.2
Imarisio, S.3
-
78
-
-
11144353613
-
SUMO modifcation of Huntingtin and Huntington's disease pathology
-
Steffan JS, Agrawal N, Pallos J et al.: SUMO modifcation of Huntingtin and Huntington's disease pathology. Science 304(5667), 100-104 (2004).
-
(2004)
Science
, vol.304
, Issue.5667
, pp. 100-104
-
-
Steffan, J.S.1
Agrawal, N.2
Pallos, J.3
-
79
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
Gunawardena S, Her LS, Brusch RG et al.: Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron 40(1), 25-40 (2003).
-
(2003)
Neuron
, vol.40
, Issue.1
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.S.2
Brusch, R.G.3
-
80
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
Steffan JS, Bodai L, Pallos J et al.: Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature 413(6857), 739-743 (2001).
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
-
81
-
-
0034629073
-
Genetic suppression of polyglutamine toxicity in Drosophila
-
Kazemi-Esfarjani P, Benzer S: Genetic suppression of polyglutamine toxicity in Drosophila. Science 287(5459), 1837-1840 (2000).
-
(2000)
Science
, vol.287
, Issue.5459
, pp. 1837-1840
-
-
Kazemi-Esfarjani, P.1
Benzer, S.2
-
82
-
-
0032168160
-
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons
-
Jackson GR, Salecker I, Dong X et al.: Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron 21(3), 633-642 (1998).
-
(1998)
Neuron
, vol.21
, Issue.3
, pp. 633-642
-
-
Jackson, G.R.1
Salecker, I.2
Dong, X.3
-
83
-
-
0037726598
-
Interaction of Akt-phosphorylated ataxin-1 with 14-13-3 mediates neurodegeneration in spinocerebellar ataxia type 1
-
Chen HK, P. Fernandez-Funez, Acevedo SF et al.: Interaction of Akt-phosphorylated ataxin-1 with 14-13-3 mediates neurodegeneration in spinocerebellar ataxia type 1. Cell 113(4), 457-468 (2003).
-
(2003)
Cell
, vol.113
, Issue.4
, pp. 457-468
-
-
Chen, H.K.1
Fernandez-Funez, P.2
Acevedo, S.F.3
-
84
-
-
18544392423
-
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
-
Warrick JM, Paulson HL, Gray-Board GL et al.: Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell 93(6), 939-949 (1998).
-
(1998)
Cell
, vol.93
, Issue.6
, pp. 939-949
-
-
Warrick, J.M.1
Paulson, H.L.2
Gray-Board, G.L.3
-
85
-
-
18144392678
-
ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma
-
Vidal M, Wells S, Ryan A, Cagan R: ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. Cancer Res. 65(9), 3538-3541 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.9
, pp. 3538-3541
-
-
Vidal, M.1
Wells, S.2
Ryan, A.3
Cagan, R.4
|