-
1
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E., Caudy A.A., Hammond S.M., and Hannon G.J. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363.
-
(2001)
Nature
, vol.409
, pp. 363
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
2
-
-
3142703151
-
Induction and biochemical purification of RNA-induced silencing complex from Drosophila S2 cells
-
Caudy A.A. and Hannon G.J. 2004. Induction and biochemical purification of RNA-induced silencing complex from Drosophila S2 cells. Methods Mol. Biol. 265: 59.
-
(2004)
Methods Mol. Biol
, vol.265
, pp. 59
-
-
Caudy, A.A.1
Hannon, G.J.2
-
3
-
-
0036792769
-
Fragile X-related protein and VIG associate with the RNA interference machinery
-
Caudy A.A., Myers M., Hannon G.J., and Hammond S.M. 2002. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev. 16: 2491.
-
(2002)
Genes Dev
, vol.16
, pp. 2491
-
-
Caudy, A.A.1
Myers, M.2
Hannon, G.J.3
Hammond, S.M.4
-
4
-
-
0033551328
-
Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase
-
Cogoni C. and Macino G. 1999. Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase. Nature 399: 166.
-
(1999)
Nature
, vol.399
, pp. 166
-
-
Cogoni, C.1
Macino, G.2
-
5
-
-
0034633770
-
AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals
-
Fagard M., Boutet S., Morel J.B., Bellini C., and Vaucheret H. 2000. AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals. Proc. Natl. Acad. Sci. 97: 11650.
-
(2000)
Proc. Natl. Acad. Sci
, vol.97
, pp. 11650
-
-
Fagard, M.1
Boutet, S.2
Morel, J.B.3
Bellini, C.4
Vaucheret, H.5
-
6
-
-
0024378286
-
The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome
-
Golic K.G. and Lindquist S. 1989. The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59: 499.
-
(1989)
Cell
, vol.59
, pp. 499
-
-
Golic, K.G.1
Lindquist, S.2
-
7
-
-
0038387645
-
In vitro analysis of RNA interference in Drosophila melanogaster
-
Haley B., Tang G., and Zamore P.D. 2003. In vitro analysis of RNA interference in Drosophila melanogaster. Methods 30: 330.
-
(2003)
Methods
, vol.30
, pp. 330
-
-
Haley, B.1
Tang, G.2
Zamore, P.D.3
-
8
-
-
0035694237
-
Identification of essential genes in cultured mammalian cells using small interfering RNAs
-
Harborth J., Elbashir S.M., Bechert K., Tuschl T., and Weber K. 2001. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J. Cell Sci. 114: 4557.
-
(2001)
J. Cell Sci
, vol.114
, pp. 4557
-
-
Harborth, J.1
Elbashir, S.M.2
Bechert, K.3
Tuschl, T.4
Weber, K.5
-
9
-
-
0032443021
-
Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
-
Kennerdell J.R. and Carthew R.W. 1998. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95: 1017.
-
(1998)
Cell
, vol.95
, pp. 1017
-
-
Kennerdell, J.R.1
Carthew, R.W.2
-
10
-
-
0033883114
-
Heritable gene silencing in Drosophila using double-stranded RNA
-
-. 2000. Heritable gene silencing in Drosophila using double-stranded RNA. Nat. Biotechnol. 18: 896.
-
(2000)
Nat. Biotechnol
, vol.18
, pp. 896
-
-
Kennerdell, J.R.1
Carthew, R.W.2
-
11
-
-
0036682990
-
RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E
-
Kennerdell J.R., Yamaguchi S., and Carthew R.W. 2002. RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E. Genes Dev. 16: 1884.
-
(2002)
Genes Dev
, vol.16
, pp. 1884
-
-
Kennerdell, J.R.1
Yamaguchi, S.2
Carthew, R.W.3
-
12
-
-
85015755518
-
Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes
-
in press
-
Kim K., Lee Y.S., and Carthew R.W. 2006. Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes. RNA (in press).
-
(2006)
RNA
-
-
Kim, K.1
Lee, Y.S.2
Carthew, R.W.3
-
13
-
-
0037711556
-
Making a better RNAi vector for Drosophila: Use of intron spacers
-
Lee Y.S. and Carthew R.W. 2003. Making a better RNAi vector for Drosophila: Use of intron spacers. Methods 30: 322.
-
(2003)
Methods
, vol.30
, pp. 322
-
-
Lee, Y.S.1
Carthew, R.W.2
-
14
-
-
1842816517
-
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
-
Lee Y.S., Nakahara K., Pham J.W., Kim K., He Z., Sontheimer E.J., and Carthew R.W. 2004. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117: 83.
-
(2004)
Cell
, vol.117
, pp. 83
-
-
Lee, Y.S.1
Nakahara, K.2
Pham, J.W.3
Kim, K.4
He, Z.5
Sontheimer, E.J.6
Carthew, R.W.7
-
15
-
-
0345359925
-
Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain
-
Lingel A., Simon B., Izaurralde E., and Sattler M. 2003. Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain. Nature 426: 465.
-
(2003)
Nature
, vol.426
, pp. 465
-
-
Lingel, A.1
Simon, B.2
Izaurralde, E.3
Sattler, M.4
-
16
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu J., Carmell M.A., Rivas F.V., Marsden C.G., Thomson J.M., Song J.J., Hammond S.M., Joshua-Tor L., and Hannon G.J. 2004. Argonaute2 is the catalytic engine of mammalian RNAi. Science 305: 1437.
-
(2004)
Science
, vol.305
, pp. 1437
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
17
-
-
0141868916
-
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
-
Liu Q., Rand T.A., Kalidas S., Du F., Kim H.E., Smith D.P., and Wang X. 2003. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301: 1921.
-
(2003)
Science
, vol.301
, pp. 1921
-
-
Liu, Q.1
Rand, T.A.2
Kalidas, S.3
Du, F.4
Kim, H.E.5
Smith, D.P.6
Wang, X.7
-
18
-
-
33746581711
-
Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes
-
Liu X., Jiang F., Kalidas S., Smith D., and Liu Q. 2006. Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes. RNA 12: 1514.
-
(2006)
RNA
, vol.12
, pp. 1514
-
-
Liu, X.1
Jiang, F.2
Kalidas, S.3
Smith, D.4
Liu, Q.5
-
19
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J., Patkaniowska A., Urlaub H., Luhrmann R., and Tuschl T. 2002. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110: 563.
-
(2002)
Cell
, vol.110
, pp. 563
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
20
-
-
27744590896
-
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
-
Matranga C., Tomari Y., Shin C., Bartel D.P., and Zamore P.D. 2005. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123: 607.
-
(2005)
Cell
, vol.123
, pp. 607
-
-
Matranga, C.1
Tomari, Y.2
Shin, C.3
Bartel, D.P.4
Zamore, P.D.5
-
21
-
-
0037335550
-
Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing
-
Myers J.W., Jones J.T., Meyer T., and Ferrell J.E. 2003. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat. Biotechnol. 21: 324.
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 324
-
-
Myers, J.W.1
Jones, J.T.2
Meyer, T.3
Ferrell, J.E.4
-
22
-
-
0034053414
-
Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics
-
Newsome T.P., Asling B., and Dickson B.J. 2000. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 127: 851.
-
(2000)
Development
, vol.127
, pp. 851
-
-
Newsome, T.P.1
Asling, B.2
Dickson, B.J.3
-
23
-
-
3142729150
-
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
-
Okamura K., Ishizuka A., Siomi H., and Siomi M.C. 2004. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev. 18: 1655.
-
(2004)
Genes Dev
, vol.18
, pp. 1655
-
-
Okamura, K.1
Ishizuka, A.2
Siomi, H.3
Siomi, M.C.4
-
24
-
-
15444368560
-
Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome
-
Orban T.I. and Izaurralde E. 2005. Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome. RNA 11: 459.
-
(2005)
RNA
, vol.11
, pp. 459
-
-
Orban, T.I.1
Izaurralde, E.2
-
25
-
-
11244279683
-
Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity
-
Parker J.S., Roe S.M., and Barford D. 2004. Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity. EMBO J. 23: 4727.
-
(2004)
EMBO J
, vol.23
, pp. 4727
-
-
Parker, J.S.1
Roe, S.M.2
Barford, D.3
-
26
-
-
27744477630
-
Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway
-
Pham J.W. and Sontheimer E.J. 2005. Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway. J. Biol. Chem. 280: 39278.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 39278
-
-
Pham, J.W.1
Sontheimer, E.J.2
-
27
-
-
1842766252
-
A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila
-
Pham J.W., Pellino J.L., Lee Y.S., Carthew R.W., and Sontheimer E.J. 2004. A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117: 83.
-
(2004)
Cell
, vol.117
, pp. 83
-
-
Pham, J.W.1
Pellino, J.L.2
Lee, Y.S.3
Carthew, R.W.4
Sontheimer, E.J.5
-
28
-
-
0036847540
-
Ribonuclease activity and RNA binding of recombinant human Dicer
-
Provost P., Dishart D., Doucet J., Frendewey D., Samuelsson B., and Radmark O. 2002. Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J. 21: 5864.
-
(2002)
EMBO J
, vol.21
, pp. 5864
-
-
Provost, P.1
Dishart, D.2
Doucet, J.3
Frendewey, D.4
Samuelsson, B.5
Radmark, O.6
-
29
-
-
27744506761
-
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
-
Rand T.A., Petersen S., Du F., and Wang X. 2005. Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123: 621.
-
(2005)
Cell
, vol.123
, pp. 621
-
-
Rand, T.A.1
Petersen, S.2
Du, F.3
Wang, X.4
-
30
-
-
4444302947
-
Crystal structure of Argonaute and its implications for RISC slicer activity
-
Song J.J., Smith S.K., Hannon G.J., and Joshua-Tor L. 2004. Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305: 1434.
-
(2004)
Science
, vol.305
, pp. 1434
-
-
Song, J.J.1
Smith, S.K.2
Hannon, G.J.3
Joshua-Tor, L.4
-
31
-
-
0037188904
-
The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans
-
Tabara H., Yigit E., Siomi H., and Mello C.C. 2002. The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans. Cell 109: 861.
-
(2002)
Cell
, vol.109
, pp. 861
-
-
Tabara, H.1
Yigit, E.2
Siomi, H.3
Mello, C.C.4
-
32
-
-
0032717319
-
The rde-1 gene, RNA interference, and transposon silencing in C. elegans
-
Tabara H., Sarkissian M., Kelly W.G., Fleenor J., Grishok A., Timmons L., Fire A., and Mello C.C. 1999. The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell 99: 123.
-
(1999)
Cell
, vol.99
, pp. 123
-
-
Tabara, H.1
Sarkissian, M.2
Kelly, W.G.3
Fleenor, J.4
Grishok, A.5
Timmons, L.6
Fire, A.7
Mello, C.C.8
-
33
-
-
1642603943
-
RISC assembly defects in the Drosophila RNAi mutant armitage
-
Tomari Y., Du T., Haley B., Schwarz D.S., Bennett R., Cook H.A., Koppetsch B.S., Theurkauf W.E., and Zamore P.D. 2004. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116: 831.
-
(2004)
Cell
, vol.116
, pp. 831
-
-
Tomari, Y.D.T.1
Haley, B.2
Schwarz, D.S.3
Bennett, R.4
Cook, H.A.5
Koppetsch, B.S.6
Theurkauf, W.E.7
Zamore, P.D.8
-
34
-
-
0034877670
-
RNA interference: Listening to the sound of silence
-
Zamore P.D. 2001. RNA interference: Listening to the sound of silence. Nat. Struct. Biol. 8: 746.
-
(2001)
Nat. Struct. Biol
, vol.8
, pp. 746
-
-
Zamore, P.D.1
|